Penetration of recombinant interleukin-2 across the blood-cerebrospinal fluid barrier.

abstract：OBJECT:Stereotactic radiosurgery is an increasingly used and the least invasive surgical option for patients with trigeminal neuralgia. In this study, the authors investigate the clinical outcomes in patients treated with this procedure. METHODS:Independently acquired data from 220 patients with idiopathic trigeminal ...

journal_title：Journal of neurosurgery

authors： Kao MC

更新日期：2002-01-01 00:00:00

abstract：OBJECT:The objective of this study was to evaluate endovascular stent therapy for carotid artery dissections (CADs). METHODS:Retrospective review of data at Millard Fillmore Gates Hospital identified 43 patients with 44 CADs (intracranial and/or extracranial) treated with carotid artery (CA) stent placement between Ja...

journal_title：Journal of neurosurgery

authors： Ohta H,Natarajan SK,Hauck EF,Khalessi AA,Siddiqui AH,Hopkins LN,Levy EI

更新日期：2011-07-01 00:00:00

abstract：OBJECT:The aim of this study was to determine the clinicopathological features of patients with intracranial bleeding from unsuspected meningioma and to relate these data to surgery-related outcome. METHODS:The authors report on two cases in which hemorrhage of an unsuspected meningioma occurred in the tentorial ridge...

journal_title：Journal of neurosurgery

authors： Bosnjak R,Derham C,Popović M,Ravnik J

更新日期：2005-09-01 00:00:00

abstract：:This report deals with a family in which the maternal grandmother, the mother, and all three male children have port-wine nevi and mega cisterna magna. Two of the three male children have, in addition, congenital communicating hydrocephalus associated with agenesis of the posterior cerebellar vermis. This case of fami...

journal_title：Journal of neurosurgery

authors： Nova HR

更新日期：1979-12-01 00:00:00

abstract：OBJECTIVE:Although the majority of patients with cerebral venous sinus thrombosis (CVST) will improve with anticoagulation therapy, a portion of patients will either present in a comatose state or continue to deteriorate clinically despite early anticoagulation. In these cases, along with treating the underlying thromb...

journal_title：Journal of neurosurgery

authors： Pasarikovski CR,Ku JC,Keith J,Ramjist J,Dobashi Y,Priola SM,da Costa L,Kumar A,Yang VXD

更新日期：2020-10-30 00:00:00

abstract：:OBJECTIVE Mineralized or desiccated colloid cysts pose some unique challenges to endoscopic removal. The extrusion of the solid matrix into the intraventricular compartment has not been previously reported and, as such, no guidance exists regarding its predilection, prevention, and fate. METHODS Postoperative imaging ...

journal_title：Journal of neurosurgery

authors： Abdel Latif AM,Souweidane MM

更新日期：2016-09-01 00:00:00

abstract：:Experimental evaluation of brain abscess has been inhibited by the lack of a simple and reproducible model in small animals. A stereotaxic headholder and slow infusion of 1 microliter of saline, containing a known number of bacteria, were used to produce brain abscess consistently in the rat. The natural history of th...

journal_title：Journal of neurosurgery

authors： Winn HR,Mendes M,Moore P,Wheeler C,Rodeheaver G

更新日期：1979-11-01 00:00:00

abstract：:Forty-two cats were subjected to decerebration, thoracic and lumbar laminectomies, and isolation of the sciatic nerves. Spinal evoked potentials in response to bilateral sciatic nerve stimulation were recorded at L-3, and the spinal cord blood flow (SCBF) was measured by the hydrogen clearance technique. Thoracic cord...

journal_title：Journal of neurosurgery

authors： Chehrazi BB,Scremin O,Decima EE

更新日期：1989-11-01 00:00:00

abstract：OBJECT:Delayed vasospasm is a significant cause of morbidity and mortality after subarachnoid hemorrhage (SAH). Proteomic therapeutics offers a new modality in which biologically active proteins or peptides are transduced into cells via covalent linkage to cell permeant peptides (CPPs). The hypothesis of this study was...

journal_title：Journal of neurosurgery

authors： Furnish EJ,Brophy CM,Harris VA,Macomson S,Winger J,Head GA,Shaver EG

更新日期：2010-03-01 00:00:00

abstract：:Two patients with chronic spinal subdural hematomas are described. Both had a fluctuating clinical course, not previously documented in the literature. Surgical evacuation resulted in almost complete recovery. The pathogenesis of spinal subdural hematoma is discussed and the pertinent literature is reviewed. ...

journal_title：Journal of neurosurgery

authors： Khosla VK,Kak VK,Mathuriya SN

更新日期：1985-10-01 00:00:00

abstract：:Acidophil stem-cell pituitary adenomas account for less than 5% of pituitary tumors. Only 15 cases have previously been reported, with a mean age of occurrence of 38.7 years. A case of this unusual tumor is reported in a prepubertal girl. Clinical symptoms included prominent behavioral disturbance with associated head...

journal_title：Journal of neurosurgery

authors： Marks WA,Brumback RA,Schaefer GB,Pendleton BD,Farris BK,Culbertson JL

更新日期：1989-02-01 00:00:00

abstract：OBJECT:The aim of this study was to compare the outcomes following macrodiscectomy and microsurgery for one-level one-sided lumbar disc excision. METHODS:The authors prospectively studied 114 consecutive patients who underwent microdiscectomy (Group A, 63 patients [36 men, 27 women]) and macrodiscectomy (Group B, 51 p...

journal_title：Journal of neurosurgery

authors： Türeyen K

更新日期：2003-10-01 00:00:00

abstract：OBJECT:Pituitary adenomas represent a large proportion of brain tumors that are increasing in incidence because of improved imaging techniques. Headache is the primary symptom in patients with large tumors (macroadenomas), but is also a symptom in patients with small tumors (microadenomas, tumors < 1.0 cm). The prevale...

journal_title：Journal of neurosurgery

authors： Fleseriu M,Yedinak C,Campbell C,Delashaw JB

更新日期：2009-02-01 00:00:00

abstract：OBJECT:The goal in this study was to review the effects of treatment plan quality on outcomes after radiosurgery for vestibular schwannoma (VS). METHODS:Between July 1988 and August 2005, 390 patients were treated. The results of this experience have been published recently. In this study the authors looked at dosimet...

journal_title：Journal of neurosurgery

authors： Beegle RD,Friedman WA,Bova FJ

更新日期：2007-11-01 00:00:00

abstract：:The authors describe a case of intracranial heterotopic brain located on the medial one-third of the left sphenoid ridge, and enveloped in a huge cystic cavity. The heterotopic brain was resected successfully with satisfactory clinical results. The resected brain was 8 X 4 X 3 cm in diameter, of 7 or 8 months gestatio...

journal_title：Journal of neurosurgery

authors： Marubayashi T,Matsukado Y

更新日期：1978-03-01 00:00:00

abstract：OBJECT:The purpose of this study was to determine if magnetic source (MS) imaging could provide useful information in the planning and performance of gamma knife radiosurgery (GKS) for epilepsy. METHODS:Magnetic source imaging of interictal epileptiform dipoles was studied in 53 epilepsy surgery candidates. All patien...

journal_title：Journal of neurosurgery

authors： Smith JR,King DW,Park YD,Lee MR,Lee GP,Jenkins PD

更新日期：2000-12-01 00:00:00

abstract：:Profound arterial hypotension is a commonly used adjunct in surgery for aneurysms and arteriovenous malformations. Hyperventilation with hypocapnia is also used in these patients to increase brain slackness. Both measures reduce cerebral blood flow (CBF). Of concern is whether CBF is reduced below ischemic thresholds ...

journal_title：Journal of neurosurgery

authors： Boarini DJ,Kassell NF,Sprowell JA,Olin JJ,Coester HC

更新日期：1985-12-01 00:00:00

abstract：:In this paper the authors trace the history of early craniometry, referring to the technique of obtaining cranial measurements for the accurate correlation of external skull landmarks to specific brain regions. Largely drawing on methods from the newly emerging fields of physical anthropology and phrenology in the lat...

journal_title：Journal of neurosurgery

authors： Serletis D,Pait TG

更新日期：2016-06-01 00:00:00

abstract：:The effect of concentrated conditioned medium from each of eight human malignant glioma cell lines on the growth of indicator cells (normal rat kidney fibroblasts (NRK), clone 14) was determined in monolayer and in soft agar assay systems. The conditioned medium from all cell lines was mitogenic in the monolayer assay...

journal_title：Journal of neurosurgery

authors： Rutka JT,Rosenblum ML,Stern R,Ralston HJ 3rd,Dougherty D,Giblin J,DeArmond S

更新日期：1989-12-01 00:00:00

abstract：OBJECT:The goal of this study was to establish the therapeutic window during which delayed therapy with MgSO4 improves neurological motor outcome in rats that have suffered severe traumatic axonal brain injury. METHODS:Severe brain injury was induced in male Sprague-Dawley rats by using the impact-acceleration model o...

journal_title：Journal of neurosurgery

authors： Heath DL,Vink R

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVES:The aim of this work was to investigate the immunohistochemical expression of nestin, a member of the intermediate filament family, in adenohypophysial vasculature during development and progression of pituitary infarction. METHODS:Forty-five nontumorous adenohypophyses and 34 pituitary adenomas of various ...

journal_title：Journal of neurosurgery

authors： Salehi F,Kovacs K,Cusimano MD,Horvath E,Bell CD,Rotondo F,Scheithauer BW

更新日期：2008-01-01 00:00:00

abstract：:OBJECTIVE Access to the third ventricle is a veritable challenge to neurosurgeons. In this context, anatomical and morphometric studies are useful for establishing the limitations and advantages of a particular surgical approach. The transchoroidal approach is versatile and provides adequate exposure of the middle and...

journal_title：Journal of neurosurgery

authors： Vitorino Araujo JL,Veiga JCE,Wen HT,de Andrade AF,Teixeira MJ,Otoch JP,Rhoton AL Jr,Preul MC,Spetzler RF,Figueiredo EG

更新日期：2017-07-01 00:00:00

abstract：:The goals of the present study were to demonstrate the ability of high-resolution ultrasonography to delineate normal nerve fascicles within or around peripheral nerve sheath tumors (NSTs). A blinded examiner evaluated 2 patients with symptomatic upper limb NSTs with high-resolution ultrasonography performed in the pe...

journal_title：Journal of neurosurgery

authors： Simon NG,Cage T,Narvid J,Noss R,Chin C,Kliot M

更新日期：2014-05-01 00:00:00

abstract：:An anatomical study of three microsurgical intraorbital routes to the optic nerve and orbital apex, which can be reached through a fronto-orbital craniotomy, was conducted on cadaver specimens. The structures that could be exposed via the medial, central, or lateral approaches directed through the orbital roof were de...

journal_title：Journal of neurosurgery

authors： Natori Y,Rhoton AL Jr

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:Ossification of pterygoalar and pterygospinous ligaments traversing the superior aspect of the infratemporal fossa results in formation of osseous bars that can obstruct percutaneous needle access to the trigeminal ganglion through the foramen ovale (FO), interfere with lateral mandibular nerve block, and imp...

journal_title：Journal of neurosurgery

authors： Matys T,Ali T,Zaccagna F,Barone DG,Kirollos RW,Massoud TF

更新日期：2019-05-10 00:00:00

abstract：:The authors report a case of multiple meningiomas in a 37-year-old woman with Rubinstein-Taybi syndrome. The patient harbored a bifrontal ossifying meningioma and multiple intracranial meningiomas. She underwent surgery for the frontal ossifying meningioma and a right frontoparietal meningioma. ...

journal_title：Journal of neurosurgery

authors： Verstegen MJ,van den Munckhof P,Troost D,Bouma GJ

更新日期：2005-01-01 00:00:00

abstract：OBJECT:The use of focal brain cooling to eliminate epileptic discharges (EDs) has attracted increasing attention in the scientific community. In this study, the inhibitory effect of selective hippocampal cooling on experimental hippocampal seizures was investigated using a newly devised cooling system with a thermoelec...

journal_title：Journal of neurosurgery

authors： Tanaka N,Fujii M,Imoto H,Uchiyama J,Nakano K,Nomura S,Fujisawa H,Kunitsugu I,Saito T,Suzuki M

更新日期：2008-04-01 00:00:00

abstract：OBJECT:Occipital encephaloceles are relatively frequently encountered. Many investigators have addressed the embryogenesis of these formations, but the dural system has never before been studied. In this retrospective analysis the authors sought to gain a better understanding of the origins of these defects. METHODS:T...

journal_title：Journal of neurosurgery

authors： Bartels RH,Merx JL,van Overbeeke JJ

更新日期：1998-11-01 00:00:00

abstract：:Liposomes have a variety of attributes as a drug delivery system. Targeting of liposomes to specific cells has been investigated by using appropriate cytophilic ligands such as monoclonal antibodies (MAb's). In the present study, liposomes with selective cytotoxicity toward glioma cells were obtained. An MAb which rea...

journal_title：Journal of neurosurgery

authors： Kito A,Yoshida J,Kageyama N,Kojima N,Yagi K

更新日期：1989-09-01 00:00:00

abstract：:The putative mechanism of vagus nerve stimulation (VNS) for medically refractory epilepsy is desynchronization of hippocampal and thalamocortical circuitry; however, the nature of the dose-response relationship and temporal dynamics is poorly understood. For greater elucidation, a study in a nonepileptic rat model was...

journal_title：Journal of neurosurgery

authors： Ilyas A,Toth E,Pizarro D,Riley KO,Pati S

更新日期：2018-11-01 00:00:00