Familial communicating hydrocephalus, posterior cerebellar agenesis, mega cisterna magna, and port-wine nevi. Report on five members of one family.

abstract：OBJECT:The authors compared and characterized several new classes of camptothecin (CPT) analogs (a total of 22 drugs) directed against human and murine glioma cell lines in vitro, trying to identify CPT analogs that can be used for local therapy in future clinical trials. Camptothecin is a naturally occurring alkaloid ...

journal_title：Journal of neurosurgery

authors： Sampath P,Amundson E,Wall ME,Tyler BM,Wani MC,Alderson LM,Colvin M,Brem H,Weingart JD

更新日期：2003-03-01 00:00:00

abstract：:OBJECTIVE Smoking is a known risk factor for aneurysm development and aneurysmal subarachnoid hemorrhage, as well as subsequent vasospasm in both untreated individuals and patients who have undergone surgical clipping of cerebrovascular aneurysms. However, there is a lack of data in the current scientific literature a...

journal_title：Journal of neurosurgery

authors： Futchko J,Starr J,Lau D,Leach MR,Roark C,Pandey AS,Thompson BG

更新日期：2018-04-01 00:00:00

abstract：:Fifty-nine cases of vertebral hemangioma were seen at the Mayo Clinic between 1980 and 1990. Vertebral hemangiomas were discovered incidentally in 35 patients, while pain was the presenting complaint in 13 patients. Five patients presented directly with progressive neurological deficit requiring surgery, and six patie...

journal_title：Journal of neurosurgery

authors： Fox MW,Onofrio BM

更新日期：1993-01-01 00:00:00

abstract：:The authors have presented 81 children with intraspinal tumors, all less than 16 years of age. The clinical features indicated that gait disturbance, pain, and sphincter disturbance are the most prominent complaints. Reflex changes, paralysis, and sensory impairment are the most frequent physical findings. Cerebrospin...

journal_title：Journal of neurosurgery

authors： DeSousa AL,Kalsbeck JE,Mealey J Jr,Campbell RL,Hockey A

更新日期：1979-10-01 00:00:00

abstract：:Ventricular asymmetries after shunt surgery were studied. Right and left ventricular areas from pre-and postoperative computerized tomography scans were measured with a computer digitizing technique, and the respective areas were expressed as a ratio. Measurements were made from the scans of 15 hydrocephalic children ...

journal_title：Journal of neurosurgery

authors： Linder M,Diehl JT,Sklar FH

更新日期：1981-08-01 00:00:00

abstract：:Needle biopsy of the brain utilizing computerized tomography (CT) scan data is an accepted diagnostic technique that has been performed both with and without the aid of stereotaxic frames. Experience with both techniques has resulted in a specific procedure for CT-guided free-hand biopsy which is performed in the CT s...

journal_title：Journal of neurosurgery

authors： Goldstein S,Gumerlock MK,Neuwelt EA

更新日期：1987-09-01 00:00:00

abstract：OBJECT:Patients with subarachnoid hemorrhage (SAH) and their close friends and family may be excessively fearful that the patient will have a recurrence, and such fears could play a critical role in the poor recovery shown by many patients The authors examined whether these fears could account for significant variance ...

journal_title：Journal of neurosurgery

authors： Covey J,Noble AJ,Schenk T

更新日期：2013-10-01 00:00:00

abstract：OBJECT:Carotid artery (CA) angioplasty with stent placement has been proposed as an alternative technique for revascularization in cases of CA stenosis. In this report the authors review the results of a multicenter Phase I study in which they evaluated the safety and feasibility of using a new self-expanding nitinol s...

journal_title：Journal of neurosurgery

authors： Qureshi AI,Suri MF,New G,Wadsworth DC Jr,Dulin J,Hopkins LN

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:Cavernous sinus meningiomas are complex tumors that offer a perpetual challenge to skull base surgeons. The senior author has employed a management strategy for these lesions aimed at maximizing tumor control while minimizing neurological morbidity. This approach emphasizes combining "safe" tumor resection an...

journal_title：Journal of neurosurgery

authors： Gozal YM,Alzhrani G,Abou-Al-Shaar H,Azab MA,Walsh MT,Couldwell WT

更新日期：2020-02-01 00:00:00

abstract：:Intracranial pressure (ICP) and continuous transcranial Doppler ultrasound signals were monitored in 20 head-injured patients and simultaneous synchronous fluctuations of middle cerebral artery (MCA) velocity and B waves of the ICP were observed. Continuous simultaneous monitoring of MCA velocity, ICP, arterial blood ...

journal_title：Journal of neurosurgery

authors： Newell DW,Aaslid R,Stooss R,Reulen HJ

更新日期：1992-03-01 00:00:00

abstract：OBJECT:Motor vehicle accidents (MVAs) are a leading cause of death and disability in young people. Given that a major cause of death from MVAs is traumatic brain injury, and neurosurgeons hold special expertise in this area relative to other members of a trauma team, the authors hypothesized that neurosurgeon populatio...

journal_title：Journal of neurosurgery

authors： Desai A,Bekelis K,Zhao W,Ball PA

更新日期：2012-09-01 00:00:00

abstract：:The authors present a surgical technique for resection of dumbbell tumors of the spine. The transparaspinal exposure combines laminectomy and sectioning of the paraspinal muscles through a transverse incision. The procedure allows total tumor resection by means of a single posterior approach in selected patients, thus...

journal_title：Journal of neurosurgery

authors： Onesti ST,Ashkenazi E,Michelsen WJ

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Although ventricular shunting is an effective therapy for idiopathic normal pressure hydrocephalus (iNPH), the effect of shunt valve type on the incidence of revision surgery is not well defined. To address this issue, shunt revision rates between patients with iNPH receiving a fixed-setting valve (FSV) versu...

journal_title：Journal of neurosurgery

authors： Rinaldo L,Bhargav AG,Nesvick CL,Lanzino G,Elder BD

更新日期：2019-06-07 00:00:00

abstract：:This 32-year-old man had noticed right leg pain for 4 years and developed classic right sciatica after heavy lifting, followed by episodes of buckling of both legs 1 month prior to admission. His medical history included congenital left abducens palsy. Examination revealed a right Lasègue's sign and Fajersztajn's sign...

journal_title：Journal of neurosurgery

authors： Holtzman RN,Jormark SC

更新日期：1996-02-01 00:00:00

abstract：OBJECT:Studies on risk factors for subarachnoid hemorrhage (SAH) show heterogeneity. For example, hypertension has been found to be a significant risk factor in some studies but not in others. The authors hypothesized that differences in the ethnicity of the populations studied could account for these findings. METHOD...

journal_title：Journal of neurosurgery

authors： Krishna V,Kim DH

更新日期：2007-09-01 00:00:00

abstract：:The purpose of this study is to report a surgical technique of nerve transfer to restore radial nerve function after a complete palsy due to a proximal injury to the radial nerve. The authors report the case of a patient who underwent direct nerve transfer of redundant or expendable motor branches of the median nerve ...

journal_title：Journal of neurosurgery

authors： Mackinnon SE,Roque B,Tung TH

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:Removal of jugular foramen (JF) tumors usually requires extensive skull base approaches and is frequently associated with postoperative morbidities such as lower cranial nerve injury. The endoscope-assisted retrosigmoid infralabyrinthine approach is a relatively new approach to tumors extending into the bony ...

journal_title：Journal of neurosurgery

authors： Samii M,Alimohamadi M,Gerganov V

更新日期：2016-04-01 00:00:00

abstract：:Ischemic stroke remains a leading cause of morbidity and death for which few therapeutic options are available. The development of neuroprotective agents, a once promising field of investigation, has failed to translate from bench to bedside successfully. This work reviews the ischemic cascade, agents targeting steps ...

journal_title：Journal of neurosurgery

authors： Turner RC,Dodson SC,Rosen CL,Huber JD

更新日期：2013-05-01 00:00:00

abstract：:Vincent van Gogh's life, letters, and art are the framework for this existential speech about the nature of alienation, as well as its threat to humanity and to the artful practice of medicine. The honest, human voice expressed in van Gogh's art stands in opposition to alienation, which occurs when we divide the world...

journal_title：Journal of neurosurgery

authors： Pelofsky S,Pelofsky R

更新日期：2002-12-01 00:00:00

abstract：OBJECT:In this paper, the authors' goals were to clarify the characteristics of growing unruptured cerebral aneurysms detected by serial MR angiography and to establish the recommended follow-up interval. METHODS:A total of 1002 patients with 1325 unruptured cerebral aneurysms were retrospectively identified. These pa...

journal_title：Journal of neurosurgery

authors： Inoue T,Shimizu H,Fujimura M,Saito A,Tominaga T

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Coverage of the anterior spinal artery (ASA) ostia is a source of considerable consternation regarding flow diversion (FD) in vertebral artery (VA) aneurysms due to cord supply. The authors sought to assess the association between coverage of the ASA, posterior spinal artery (PSA), or lateral spinal artery (L...

journal_title：Journal of neurosurgery

authors： Dmytriw AA,Kapadia A,Enriquez-Marulanda A,Parra-Fariñas C,Kühn AL,Nicholson PJ,Waqas M,Renieri L,Michelozzi C,Foreman PM,Phan K,Yang IH,Tutino VM,Ogilvy CS,Radovanovic I,Harrigan MR,Siddiqui AH,Levy EI,Limbucci N,Co

更新日期：2020-03-27 00:00:00

abstract：:A computer-based system has been developed for the integration and display of computerized tomography (CT) image data in the operating microscope in the correct perspective without requiring a stereotaxic frame. Spatial registration of the CT image data is accomplished by determination of the position of the operating...

journal_title：Journal of neurosurgery

authors： Roberts DW,Strohbehn JW,Hatch JF,Murray W,Kettenberger H

更新日期：1986-10-01 00:00:00

abstract：:The author describes a woman in whom an S1-2 fracture developed after L4-S1 decompression and fusion. Osteoporosis was not present, but the lesion failed to respond to conservative therapy, necessitating surgical extension of the spinal fusion. Although biomechanical complications of lumbosacral fusion are uncommon, p...

journal_title：Journal of neurosurgery

authors： Bose B

更新日期：2003-10-01 00:00:00

abstract：:The case of a 30-year-old woman with Chiari I malformation and a cervicothoracic syrinx is presented. The patient was followed clinically over a 2 1/2-year period. Spontaneous and complete resolution of the syrinx, as documented by serial magnetic resonance studies, was accompanied by only a minimal change in objectiv...

journal_title：Journal of neurosurgery

authors： Jack CR Jr,Kokmen E,Onofrio BM

更新日期：1991-02-01 00:00:00

abstract：:The authors have designed an experiment to detect a hitherto unrecognized interaction between high doses of the glucocorticoid, dexamethasone, and brain irradiation. Eighteen juvenile male rhesus monkeys received 1800 rads to the whole brain in 8.5 minutes. For 1 1/2 days before and 10 1/2 days after the irradiation, ...

journal_title：Journal of neurosurgery

authors： Martins AN,Severance RE,Henry JM,Doyle TF

更新日期：1979-11-01 00:00:00

abstract：:Bilateral and simultaneous sampling of the inferior petrosal sinuses in patients with Cushing's disease has been used to establish the presence and laterality of adrenocorticotropic hormone (ACTH)-producing microadenomas prior to transsphenoidal surgery. Successful preoperative lateralization depends upon equivalent d...

journal_title：Journal of neurosurgery

authors： Zovickian J,Oldfield EH,Doppman JL,Cutler GB Jr,Loriaux DL

更新日期：1988-02-01 00:00:00

abstract：OBJECT:Symptoms from Parkinson's disease improve after surgical ablation of the medial globus pallidus (GPm). Although, in theory, selective chemical ablation of neurons in the GPm could preserve vital structures jeopardized by surgery, the potential of this approach is limited when using traditional techniques of drug...

journal_title：Journal of neurosurgery

authors： Lieberman DM,Corthesy ME,Cummins A,Oldfield EH

更新日期：1999-05-01 00:00:00

abstract：OBJECT:The aim of this study was to evaluate the causes of treatment failure in patients with arteriovenous malformations (AVMs) who underwent radiosurgery, which is increasingly used as a treatment method for selected, surgically high-risk AVMs. Unfortunately, radiosurgical treatment fails in a small but significant p...

journal_title：Journal of neurosurgery

authors： Ellis TL,Friedman WA,Bova FJ,Kubilis PS,Buatti JM

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:Camptocormia is a potentially debilitating condition in the progression of Parkinson's disease (PD). It is described as an abnormal forward flexion while standing that resolves when lying supine. Although the condition is relatively common, the underlying pathophysiology and optimal treatment strategy are unc...

journal_title：Journal of neurosurgery

authors： Chan AK,Chan AY,Lau D,Durcanova B,Miller CA,Larson PS,Starr PA,Mummaneni PV

更新日期：2018-09-14 00:00:00

abstract：OBJECT:The authors sought to determine the incidence, time course, and risk factors for overall adverse radiation effect (ARE) and symptomatic ARE after stereotactic radiosurgery (SRS) for brain metastases. METHODS:All cases of brain metastases treated from 1998 through 2009 with Gamma Knife SRS at UCSF were considere...

journal_title：Journal of neurosurgery

authors： Sneed PK,Mendez J,Vemer-van den Hoek JG,Seymour ZA,Ma L,Molinaro AM,Fogh SE,Nakamura JL,McDermott MW

更新日期：2015-08-01 00:00:00