The science of cerebral ischemia and the quest for neuroprotection: navigating past failure to future success.

abstract：:Of 410 patients with refractory herniated lumbar disc disease treated with intradiscal collagenase, 82 (20%) did not respond to enzyme treatment and subsequently underwent surgery. Failure to improve in 6 to 8 weeks was the predominant cause for surgical intervention (53 patients). Increased pain (18 patients), progre...

journal_title：Journal of neurosurgery

authors： Fisher RG,Bromley JW,Becker GL,Brown M,Mooney V

更新日期：1986-04-01 00:00:00

abstract：:To determine if dexamethasone administered by osmotic pump directly to brain tumors would control peritumoral edema and at the same time suppress tumor growth and prolong survival, the authors studied experimental brain tumors produced in 102 rabbits by implanting VX2 carcinoma cells. Of these, 58 animals were separat...

journal_title：Journal of neurosurgery

authors： Ikeda Y,Carson BS,Lauer JA,Long DM

更新日期：1993-11-01 00:00:00

abstract：OBJECT:Diffuse axonal injury (DAI) is a major complication of traumatic brain injury (TBI) that leads to functional and psychological deficits. Although DAI is frequently underdiagnosed by conventional imaging modalities, it can be demonstrated using diffusion tensor imaging. The aim of this study was to assess the pre...

journal_title：Journal of neurosurgery

authors： Inglese M,Makani S,Johnson G,Cohen BA,Silver JA,Gonen O,Grossman RI

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:Herein, the authors report their experience with intraoperative stimulation mapping to locate the descending subcortical motor pathways in patients undergoing surgery for hemispheric gliomas within or adjacent to the rolandic cortex, with particular description of the morbidity and functional outcomes associa...

journal_title：Journal of neurosurgery

authors： Han SJ,Morshed RA,Troncon I,Jordan KM,Henry RG,Hervey-Jumper SL,Berger MS

更新日期：2018-08-17 00:00:00

abstract：OBJECT:The goal of this study was to assess the accuracy of the routine clinical use of transcranial Doppler (TCD) ultrasonography and SPECT in predicting angiographically demonstrated vasospasm. METHODS:Following receipt of institutional review board approval, the authors reviewed the records of patients with subarac...

journal_title：Journal of neurosurgery

authors： Kincaid MS,Souter MJ,Treggiari MM,Yanez ND,Moore A,Lam AM

更新日期：2009-01-01 00:00:00

abstract：:Ventricular catheter replacement can be challenging, especially in patients with small ventricles. Shunt malfunction due to ventricular catheter obstruction can occur without ventricular enlargement, such as in the setting of slit-ventricle syndrome or benign intracranial hypertension. The authors describe a simple te...

journal_title：Journal of neurosurgery

authors： Omahen DA,Hentschel SJ,Cameron GS

更新日期：2011-09-01 00:00:00

abstract：:OBJECTIVECerebral cavernous malformations (CCMs) are frequently diagnosed vascular malformations of the brain. Although most CCMs are asymptomatic, some can be responsible for intracerebral hemorrhage or seizures. In selected cases, microsurgical resection is the preferred treatment option. Treatment with the unselect...

journal_title：Journal of neurosurgery

authors： Goldberg J,Jaeggi C,Schoeni D,Mordasini P,Raabe A,Bervini D

更新日期：2018-06-15 00:00:00

abstract：OBJECT:To provide greater accuracy in determining the epileptogenic zone during preoperative evaluation, the authors retrospectively examined 123I-iomazenil single-photon emission computed tomography (IMZ SPECT) studies obtained in patients with temporal lobe epilepsy (TLE) in whom there was no evidence of an abnormali...

journal_title：Journal of neurosurgery

authors： Umeoka S,Matsuda K,Baba K,Usui N,Tottori T,Terada K,Usui K,Nakamura F,Inoue Y,Fujiwara T,Mihara T

更新日期：2007-08-01 00:00:00

abstract：OBJECT:The authors report the 3-year results of the Barrow Ruptured Aneurysm Trial (BRAT). The objective of this ongoing randomized trial is to compare the safety and efficacy of microsurgical clip occlusion and endovascular coil embolization for the treatment of acutely ruptured cerebral aneurysms and to compare funct...

journal_title：Journal of neurosurgery

authors： Spetzler RF,McDougall CG,Albuquerque FC,Zabramski JM,Hills NK,Partovi S,Nakaji P,Wallace RC

更新日期：2013-07-01 00:00:00

abstract：:Intracranial occurrence of follicular dendritic cell (FDC) sarcoma, a rare tumor derived from dendritic cells of the lymphoid follicle, has not yet been described. Therefore, the case of a 53-year-old man presenting with an intracranial mass invading the clivus is reported. The diagnosis of FDC sarcoma was confirmed b...

journal_title：Journal of neurosurgery

authors： Hasselblatt M,Sepehrnia A,von Falkenhausen M,Paulus W

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the anatomical consistency, morphology, axonal connectivity, and correlative topography of the dorsal component of the superior longitudinal fasciculus (SLF-I) since the current literature is limited and ambiguous. METHODS:Fifteen normal, adult, formalin-fixed cerebra...

journal_title：Journal of neurosurgery

authors： Komaitis S,Skandalakis GP,Kalyvas AV,Drosos E,Lani E,Emelifeonwu J,Liakos F,Piagkou M,Kalamatianos T,Stranjalis G,Koutsarnakis C

更新日期：2019-03-01 00:00:00

abstract：:The theory of immune surveillance postulates that one function of the immune system is to eliminate small numbers of malignant cells that arise spontaneously within the organism. Although there has been a great deal of both clinical and experimental evidence in favor of thistheory as it applies to general oncology, th...

journal_title：Journal of neurosurgery

authors： Morantz RA,Shain W,Cravioto H

更新日期：1978-07-01 00:00:00

abstract：OBJECT:Cerebral hemispherectomy for intractable seizures has evolved over the past 50 years, and current operations focus less on brain resection and more on disconnection. In addition, cases involving cortical dysplasia and Rasmussen encephalitis are being identified and surgically treated in younger individuals. Few ...

journal_title：Journal of neurosurgery

authors： Cook SW,Nguyen ST,Hu B,Yudovin S,Shields WD,Vinters HV,Van de Wiele BM,Harrison RE,Mathern GW

更新日期：2004-02-01 00:00:00

abstract：OBJECT:Intracranial hemorrhage associated with cerebral hyperperfusion syndrome (CHS) following carotid endarterectomy (CEA) or carotid artery stenting (CAS) is a rare but potentially devastating complication. In the present study the authors evaluated 4494 patients with carotid artery stenosis who had undergone CEA or...

journal_title：Journal of neurosurgery

authors： Ogasawara K,Sakai N,Kuroiwa T,Hosoda K,Iihara K,Toyoda K,Sakai C,Nagata I,Ogawa A,Japanese Society for Treatment at Neck in Cerebrovascular Disease Study Group.

更新日期：2007-12-01 00:00:00

abstract：:Four cases of trigeminal neurinoma are reviewed with particular attention to clinical signs and symptoms, lumbar puncture, electroencephalogram, brain scan, plain skull and tomographic radiographs, and angiographic and pneumoencephalographic findings. Pneumoencephalography, with special tomographic projections to iden...

journal_title：Journal of neurosurgery

authors： Levinthal R,Benston JR

更新日期：1976-11-01 00:00:00

abstract：OBJECT:A growing number of published studies have recently demonstrated the role of resection in overall survival (OS) for patients with gliomas. In this retrospective study, the authors objectively investigated the role of the extent of resection (EOR) in OS in patients with low-grade gliomas (LGGs). METHODS:Between ...

journal_title：Journal of neurosurgery

authors： Ius T,Isola M,Budai R,Pauletto G,Tomasino B,Fadiga L,Skrap M

更新日期：2012-12-01 00:00:00

abstract：:This report describes a new and reliable technique for producing experimental noncommunicating syringomyelia. In 30 rats, 1.2 to 1.6 microliters of kaolin was microinjected into the dorsal columns and central gray matter of the spinal cord at C-6. The inoculations caused transient neurological deficits in four animals...

journal_title：Journal of neurosurgery

authors： Milhorat TH,Nobandegani F,Miller JI,Rao C

更新日期：1993-02-01 00:00:00

abstract：:Calcified cervical intervertebral discs in children are manifestations of an uncommon, distinct disease of unknown cause. Acute symptoms are usually followed by a benign course of spontaneous recovery, frequently culminating in resorption of the calcium. Rarely herniation of the disc may cause neurological complicatio...

journal_title：Journal of neurosurgery

authors： Smith RA,Vohman MD,Dimon JH 3rd,Averett JE Jr,Milsap JH Jr

更新日期：1977-02-01 00:00:00

abstract：:Although posterior plates are increasingly used to manage cervical spinal instability, long-term follow-up evaluation of patients with a critical analysis of efficacy and complications has not been reported. The authors have retrospectively analyzed the outcome in 44 consecutive patients (37 males and seven females, a...

journal_title：Journal of neurosurgery

authors： Fehlings MG,Cooper PR,Errico TJ

更新日期：1994-09-01 00:00:00

abstract：:The expanding use of intrathecal baclofen for spasticity has raised a concern about the treatment of overdose in these patients, since no specific baclofen antagonist is available. Since physostigmine has been reported to reverse the respiratory depression and somnolence due to opiates, the drug was tried for the trea...

journal_title：Journal of neurosurgery

authors： Müller-Schwefe G,Penn RD

更新日期：1989-08-01 00:00:00

abstract：OBJECT:The authors studied the microsurgical anatomy of the ophthalmic artery (OphA), paying particular attention to its possibly dangerous anastomoses with the middle meningeal artery (MMA). METHODS:The microsurgical anatomy of the OphA and its anastomoses with the MMA were studied in 14 vessels from seven adult cada...

journal_title：Journal of neurosurgery

authors： Perrini P,Cardia A,Fraser K,Lanzino G

更新日期：2007-01-01 00:00:00

abstract：OBJECT:Ventricular infection after ventriculostomy placement carries a high mortality rate. Responding to ventriculostomy infection rates, a multidisciplinary performance improvement team was formed, a comprehensive protocol for ventriculostomy placement was developed, and the efficacy was evaluated. METHODS:A best-pr...

journal_title：Journal of neurosurgery

authors： Kubilay Z,Amini S,Fauerbach LL,Archibald L,Friedman WA,Layon AJ

更新日期：2013-03-01 00:00:00

abstract：OBJECT:The use of nicardipine prolonged-release implants (NPRIs) is associated with a significant improvement in the therapy of patients suffering from aneurysmal subarachnoid hemorrhage (aSAH) regarding the occurrence and severity of cerebral vasospasm, new infarcts, and functional outcome (FO). Because quality of lif...

journal_title：Journal of neurosurgery

authors： Barth M,Thomé C,Schmiedek P,Weiss C,Kasuya H,Vajkoczy P

更新日期：2009-05-01 00:00:00

abstract：:The purpose of this study is to report a surgical technique of nerve transfer to restore radial nerve function after a complete palsy due to a proximal injury to the radial nerve. The authors report the case of a patient who underwent direct nerve transfer of redundant or expendable motor branches of the median nerve ...

journal_title：Journal of neurosurgery

authors： Mackinnon SE,Roque B,Tung TH

更新日期：2007-09-01 00:00:00

abstract：OBJECT:Dissections were performed in 100 fresh cadaver palms to determine the frequency with which superficial palmar communication between the median and ulnar nerves occurs and to what extent it might incur iatrogenic injury during endoscopic carpal tunnel release. METHODS:Superficial palmar communication between th...

journal_title：Journal of neurosurgery

authors： Stancić MF,Mićović V,Potocnjak M

更新日期：1999-12-01 00:00:00

abstract：OBJECT:The malignant progression of benign tumors is well documented in gliomas and other systemic lesions. It is also well known that some meningiomas become progressively aggressive despite their original benign status. The theory of clonal evolution is widely believed to explain malignant progression in meningioma; ...

journal_title：Journal of neurosurgery

authors： Al-Mefty O,Kadri PA,Pravdenkova S,Sawyer JR,Stangeby C,Husain M

更新日期：2004-08-01 00:00:00

abstract：OBJECT:The aims of this study were to determine the following: whether there are sex differences in intracerebral hemorrhage (ICH) induced brain injury in rats, whether delayed administration of 17beta-estradiol can reduce ICH-induced brain damage, and whether these effects are estrogen receptor (ER)-dependent. METHOD...

journal_title：Journal of neurosurgery

authors： Nakamura T,Hua Y,Keep RF,Park JW,Xi G,Hoff JT

更新日期：2005-07-01 00:00:00

abstract：:A 24-year-old man presented with a history of recurrent meningitis secondary to cerebrospinal fluid (CSF) rhinorrhea. The patient had bilateral optic disc dysplasia in association with a basal encephalocele, but had no midline facial anomalies. The syndrome is rare, and this is the first report of a patient with this ...

journal_title：Journal of neurosurgery

authors： Bullard DE,Crockard HA,McDonald WI

更新日期：1981-06-01 00:00:00

abstract：:The authors report a case of subarachnoid hemorrhage in an 11-month-old infant with tragic outcome. Radiological investigation showed an anterior communicating aneurysm, and postmortem examination confirmed the aneurysm to be a so-called "berry" aneurysm. There were also typical signs of fibromuscular hyperplasia of t...

journal_title：Journal of neurosurgery

authors： Bolander H,Hassler O,Liliequist B,West KA

更新日期：1978-11-01 00:00:00

abstract：:Consecutive paraffin sections of 105 astrocytomas and 15 oligoastrocytomas were examined for expression of p53, MIB-1 (Ki-67), and proliferating cell nuclear antigen (PCNA). The tumors had been examined previously for genetic abnormalities and by flow cytometry. Regardless of the tumor's stage and grade and the patien...

journal_title：Journal of neurosurgery

authors： Cunningham JM,Kimmel DW,Scheithauer BW,O'Fallon JR,Novotny PJ,Jenkins RB

更新日期：1997-01-01 00:00:00