Noncommunicating syringomyelia following occlusion of central canal in rats. Experimental model and histological findings.

Abstract:

:This report describes a new and reliable technique for producing experimental noncommunicating syringomyelia. In 30 rats, 1.2 to 1.6 microliters of kaolin was microinjected into the dorsal columns and central gray matter of the spinal cord at C-6. The inoculations caused transient neurological deficits in four animals and no deficits in 26 animals. Within 24 hours, kaolin and polymorphonuclear leukocytes entered the central canal and drained rostrally. The clearance of inflammatory products induced a proliferation of ependymal cells and periependymal fibrous astrocytes, which formed synechiae and obstructed the canal at the level of injection and at one or more levels up to C-1. In 22 animals followed for 48 hours or longer, the upper end of the central canal became acutely dilated and formed an ependyma-lined syrinx that enlarged to massive dimensions within 6 weeks. The rostral syrinxes did not communicate with the fourth ventricle and were not associated with hydrocephalus. The histological findings in acute noncommunicating syringomyelia were characterized by progressive stretching and thinning of the ependyma, elongation of intracanalicular septae, and the formation of periependymal edema. After 3 weeks, there was progressive compression of the periependymal tissues associated with stretching of axons, fragmentation of myelin sheaths, and the formation of myelin droplets. These findings and the sequence in which they evolved were identical in most respects to those occurring in acute and subacute noncommunicating hydrocephalus.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Milhorat TH,Nobandegani F,Miller JI,Rao C

doi

10.3171/jns.1993.78.2.0274

subject

Has Abstract

pub_date

1993-02-01 00:00:00

pages

274-9

issue

2

eissn

0022-3085

issn

1933-0693

journal_volume

78

pub_type

杂志文章
  • Human caudate nucleus subdivisions in tinnitus modulation.

    abstract:OBJECTIVE:The object of this study was to define caudate nucleus locations responsive to intraoperative direct electrical stimulation for tinnitus loudness modulation and relate those locations to functional connectivity maps between caudate nucleus subdivisions and auditory cortex. METHODS:Six awake study participant...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2018.10.JNS181659

    authors: Perez PL,Wang SS,Heath S,Henderson-Sabes J,Mizuiri D,Hinkley LB,Nagarajan SS,Larson PS,Cheung SW

    更新日期:2019-02-08 00:00:00

  • Radiosurgery for benign tumors of the spine using the Synergy S with cone-beam computed tomography image guidance.

    abstract:OBJECT:There is a growing body of evidence to support the safe and effective use of spine radiosurgery. However, there is much less experience regarding the use of radiosurgery for the treatment of benign as opposed to malignant spine tumors. This study represents an evaluation of, and reporting on, the technical aspec...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2012.8.GKS12981

    authors: Gerszten PC,Chen S,Quader M,Xu Y,Novotny J Jr,Flickinger JC

    更新日期:2012-12-01 00:00:00

  • Subependymomas of the fourth ventricle. Surgical treatment in 12 cases.

    abstract::Subependymomas of the fourth ventricle are generally considered incidental postmortem findings, and have received scant attention from neurosurgeons. The authors present a surgical series of 12 cases of this disorder diagnosed over a 13-year period. The clinical and radiological findings were reviewed and correlations...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1985.62.4.0508

    authors: Jooma R,Torrens MJ,Bradshaw J,Brownell B

    更新日期:1985-04-01 00:00:00

  • In-hospital mortality and length of hospital stay with craniotomy versus craniectomy for acute subdural hemorrhage: a multicenter, propensity score-matched analysis.

    abstract:OBJECTIVE:The optimal surgical treatment for acute subdural hemorrhage (ASDH) remains controversial. The purpose of this study was to compare outcomes in patients who underwent craniotomy with those in patients who underwent decompressive craniectomy for the treatment of ASDH. METHODS:Using the Japan Trauma Data Bank,...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2019.4.JNS182660

    authors: Shibahashi K,Sugiyama K,Tomio J,Hoda H,Morita A

    更新日期:2019-06-21 00:00:00

  • A new model of transient hindbrain ischemia in gerbils.

    abstract::A model of transient hindbrain ischemia in Mongolian gerbils is described. The vertebrobasilar junction of gerbils was exposed by a transcervical approach through the space between the atlas and occipital bone. The origin of the basilar artery was occluded by a clip, and the local cerebral blood flow (CBF) was measure...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.60.5.1054

    authors: Yamada K,Hayakawa T,Yoshimine T,Ushio Y

    更新日期:1984-05-01 00:00:00

  • Factors predicting language lateralization in patients with perisylvian vascular malformations. Clinical article.

    abstract:OBJECT:The authors conducted a study to determine the factors associated with right-sided language dominance in patients with cerebrovascular malformations. METHODS:Twenty-two patients with either arteriovenous malformations (AVMs [15 cases]) or cavernous malformations (7 cases) underwent functional MR (fMR) imaging s...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2010.2.JNS091595

    authors: Lee DJ,Pouratian N,Bookheimer SY,Martin NA

    更新日期:2010-10-01 00:00:00

  • Thalamic deep brain stimulation for writer's cramp.

    abstract:OBJECT:Writer's cramp is a type of idiopathic focal hand dystonia characterized by muscle cramps that accompany execution of the writing task specifically. In this report, the authors describe the clinical outcome after thalamic deep brain stimulation (DBS) therapy in patients with writer's cramp and present an illustr...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/JNS-07/11/0977

    authors: Fukaya C,Katayama Y,Kano T,Nagaoka T,Kobayashi K,Oshima H,Yamamoto T

    更新日期:2007-11-01 00:00:00

  • Computer-derived density spectral array in detection of mild analog electroencephalographic ischemic pattern changes during carotid endarterectomy.

    abstract::The purpose of this prospective study was twofold: 1) to determine the sensitivity and specificity of computer-derived density spectral array in detecting analog electroencephalographic (EEG) ischemic pattern changes during carotid artery cross-clamping in patients undergoing carotid endarterectomy; and 2) to assess t...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1993.78.6.0884

    authors: Kearse LA Jr,Martin D,McPeck K,Lopez-Bresnahan M

    更新日期:1993-06-01 00:00:00

  • Desmoid-type fibromatoses involving the brachial plexus: treatment options and assessment of c-KIT mutational status.

    abstract:OBJECT:Desmoid-type fibromatoses are a locally invasive soft-tissue lesion that is most commonly encountered in abdominal sites. The tumor also affects head and neck areas, particularly the supraclavicular region, where it may encase and distort the brachial plexus and compromise neurovascular structures. Neurosurgeons...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2006.104.5.749

    authors: Seinfeld J,Kleinschmidt-Demasters BK,Tayal S,Lillehei KO

    更新日期:2006-05-01 00:00:00

  • Posterior fossa volume in children with Chiari malformation Type I.

    abstract:OBJECT:The authors sought to establish whether the volume of the posterior fossa in children suffering from Chiari malformation Type I (CM-I) is smaller than normal, as has been suggested previously. They also investigated the role of syringomyelia in posterior fossa development. METHODS:Both posterior fossa volume (P...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2006.105.2.101

    authors: Sgouros S,Kountouri M,Natarajan K

    更新日期:2006-08-01 00:00:00

  • Cortical plasticity of motor-eloquent areas measured by navigated transcranial magnetic stimulation in patients with glioma.

    abstract::OBJECTIVE The goal of this study was to obtain a better understanding of the mechanisms underlying cerebral plasticity. Coupled with noninvasive detection of its occurrence, such an understanding has huge potential to improve glioma therapy. The authors aimed to demonstrate the frequency of plastic reshaping, find clu...

    journal_title:Journal of neurosurgery

    pub_type: 评论,杂志文章

    doi:10.3171/2016.9.JNS161595

    authors: Conway N,Wildschuetz N,Moser T,Bulubas L,Sollmann N,Tanigawa N,Meyer B,Krieg SM

    更新日期:2017-11-01 00:00:00

  • Facial diplegia revealing ventriculoperitoneal shunt failure in a patient with Crouzon syndrome. Case report.

    abstract::The authors report on the case of a 15-year-old boy with Crouzon syndrome (CS) who presented with headache and facial diplegia. He had undergone several craniofacial interventions and a posterior fossa decompression for tonsillar herniation caused by the CS. A ventriculoperitoneal (VP) shunt had been inserted for hydr...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/PED-07/07/046

    authors: Thines L,Vinchon M,Lahlou A,Pellerin P,Dhellemmes P

    更新日期:2007-07-01 00:00:00

  • A comparative study on ventriculographic and computerized tomography-guided determinations of brain targets in functional stereotaxis.

    abstract::Thalamic, pallidal, and hypothalamic targets were determined in 16 patients by a stereotactic computerized tomography (CT) study using a noninvasive technique with Laitinen's Stereoadapter. At surgery, the Stereoadapter was remounted to the head and the stereotactic CT coordinates were transferred to the Stereoguide w...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1990.73.4.0565

    authors: Hariz MI,Bergenheim AT

    更新日期:1990-10-01 00:00:00

  • Magnetoencephalographic mapping of the language-specific cortex.

    abstract:OBJECT:In this paper the authors introduce a novel use of magnetoencephalography (MEG) for noninvasive mapping of language-specific cortex in individual patients and in healthy volunteers. METHODS:The authors describe a series of six experiments in which normative MEG data were collected and the reliability, validity,...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1999.90.1.0085

    authors: Papanicolaou AC,Simos PG,Breier JI,Zouridakis G,Willmore LJ,Wheless JW,Constantinou JE,Maggio WW,Gormley WB

    更新日期:1999-01-01 00:00:00

  • Do tumor and ventricular volume predict the need for postresection shunting in colloid cyst patients?

    abstract::OBJECTIVE Many colloid cyst patients present with obstructive hydrocephalus that resolves after resection of the cyst. However, a proportion of patients with these cysts will require cerebrospinal fluid shunting after tumor resection, despite resolution of the obstruction at the foramina of Monro. The goal of this stu...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2015.9.JNS151183

    authors: Weaver KJ,McCord M,Neal D,Bova F,Rajon D,Quinones-Hinojosa A,Rahman M

    更新日期:2016-09-01 00:00:00

  • Neuroepithelial cyst of the fourth ventricle. Case report.

    abstract::Developmental cysts lined by neuroepithelium are a distinctive form of neural tube dysgenesis. Neuropathological study of fourth ventricular cysts that caused symptomatic hydrocephalus indicated its neuroepithelial origin. The cyst arose from the ventral surface of cerebellar vermis. Evagination of the rhombencephalic...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1977.46.6.0820

    authors: Sharpe JA,Deck JH

    更新日期:1977-06-01 00:00:00

  • Intraoperative subcortical mapping of a language-associated deep frontal tract connecting the superior frontal gyrus to Broca's area in the dominant hemisphere of patients with glioma.

    abstract:OBJECT:The deep frontal pathway connecting the superior frontal gyrus to Broca's area, recently named the frontal aslant tract (FAT), is assumed to be associated with language functions, especially speech initiation and spontaneity. Injury to the deep frontal lobe is known to cause aphasia that mimics the aphasia cause...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2014.10.JNS14945

    authors: Fujii M,Maesawa S,Motomura K,Futamura M,Hayashi Y,Koba I,Wakabayashi T

    更新日期:2015-06-01 00:00:00

  • The pineal gland: anatomy, physiology, and clinical significance.

    abstract::Since the discovery of melatonin approximately 25 years ago, there has been intense study regarding the details of the structure and function of the pineal gland. This work is reviewed, with particular emphasis on those aspects of importance to human physiology and disease. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.1985.63.3.0321

    authors: Erlich SS,Apuzzo ML

    更新日期:1985-09-01 00:00:00

  • Intrathecal colistin for treatment of highly resistant Pseudomonas ventriculitis. Case report and review of the literature.

    abstract::Nosocomial infections with organisms resistant to multiple antibiotic agents represent an evolving challenge in the intensive care setting, particularly in patients requiring surgical diversion of cerebrospinal fluid. The authors present the case of a 51-year-old woman who endured protracted hospitalization and requir...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.2005.102.5.0915

    authors: Gump WC,Walsh JW

    更新日期:2005-05-01 00:00:00

  • Use of a resorbable sheet in iliac crest reconstruction in a sheep model.

    abstract:OBJECT:Iliac crest bone graft harvesting can result in major complications, the rates of which range from approximately 6 to 8%. The objective of this study was to evaluate the postoperative regeneration of iliac crest donor defects in an animal model after harvesting a full-thickness tricortical graft. METHODS:In ske...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/spi.2002.97.4.0456

    authors: Cornwall GB,Wheeler DL,Thomas KA,Taylor WR,Turner AS

    更新日期:2002-11-01 00:00:00

  • Development of experimental meningeal gliomatosis models in rats.

    abstract::Experimental models of meningeal gliomatosis (MG) have been produced by intracisternal inoculation of rat C6 and 9L glioma cells into Wistar and Fischer 344 rats, respectively. Tumor growth was steady and rapid in both MG models when more than 10(6) tumor cells were implanted. The median survival time of the rats inoc...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1986.65.4.0503

    authors: Yoshida T,Shimizu K,Ushio Y,Hayakawa T,Arita N,Mogami H

    更新日期:1986-10-01 00:00:00

  • Transcranial approach to the orbit: microsurgical anatomy.

    abstract::An anatomical study of three microsurgical intraorbital routes to the optic nerve and orbital apex, which can be reached through a fronto-orbital craniotomy, was conducted on cadaver specimens. The structures that could be exposed via the medial, central, or lateral approaches directed through the orbital roof were de...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1994.81.1.0078

    authors: Natori Y,Rhoton AL Jr

    更新日期:1994-07-01 00:00:00

  • Long-term follow-up studies of Gamma Knife surgery with a low margin dose for vestibular schwannoma.

    abstract:OBJECT:The aim of this study was to assess long-term clinical outcomes in patients who underwent Gamma Knife surgery (GKS) with a low margin dose-14 Gy or less-to treat vestibular schwannoma (VS) unrelated to neurofibromatosis Type II. METHODS:Between December 1994 and December 2001, 200 patients with VSs underwent GK...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2012.7.GKS12783

    authors: Sun S,Liu A

    更新日期:2012-12-01 00:00:00

  • Unoperated subdural hematomas. Long-term follow-up study by brain scan and electroencephalography.

    abstract::The authors report nine patients selected from over 100 patients with subdural hematomas successfully treated without surgery. These patients were followed for as long as 5 years. All had angiographically demonstrated subdural hematomas. Electroencephalograms (EEG) documented well the clinical improvement of the patie...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1976.44.5.0601

    authors: Lusins J,Jaffe R,Bender MB

    更新日期:1976-05-01 00:00:00

  • Comparison of techniques for ventriculoperitoneal shunting in 523 patients with subarachnoid hemorrhage.

    abstract:OBJECTIVE:It is common practice to use a new contralateral bur hole for ventriculoperitoneal shunt (VPS) placement in subarachnoid hemorrhage (SAH) patients with an existing ventriculostomy. At Thomas Jefferson University and Jefferson Hospital for Neuroscience, the authors have primarily used the ventriculostomy site ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2014.6.JNS132638

    authors: Chalouhi N,Whiting A,Anderson EC,Witte S,Zanaty M,Tjoumakaris S,Gonzalez LF,Hasan D,Starke RM,Hann S,Ghobrial GM,Rosenwasser R,Jabbour P

    更新日期:2014-10-01 00:00:00

  • Navigated transcranial magnetic stimulation for preoperative language mapping in a patient with a left frontoopercular glioblastoma.

    abstract::Up to now, navigated transcranial magnetic stimulation (nTMS) has been used for motor mapping in the vicinity of rolandic brain lesions. Recently, nTMS has also been suggested to be useful in mapping human language areas. The authors describe the case of a left-handed patient with a left-side glioblastoma within the...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2012.9.JNS121053

    authors: Sollmann N,Picht T,Mäkelä JP,Meyer B,Ringel F,Krieg SM

    更新日期:2013-01-01 00:00:00

  • ICP patterns and isotope cisternography in patients with communicating hydrocephalus following rupture of intracranial aneurysm.

    abstract::Intracranial pressure (ICP) was continuously recorded, isotope cisternography was performed, and the ventricular system size was evaluated on serial computerized tomography scans in 39 patients. All of these patients had communicating hydrocephalus after subarachnoid hemorrhage (SAH) from rupture of an intracranial an...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1985.62.2.0220

    authors: Hayashi M,Kobayashi H,Kawano H,Handa Y,Yamamoto S,Kitano T

    更新日期:1985-02-01 00:00:00

  • Radiosurgery for trigeminal neuralgia: is sensory disturbance required for pain relief?

    abstract:OBJECT:Over the past 15 years stereotactic radiosurgery has become an accepted surgical option for patients with medically unresponsive trigeminal neuralgia (TN). The mechanism whereby radiosurgery causes pain relief remains unclear. METHODS:A review of recent papers on the radiosurgical management of TN reveals a cor...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/sup.2006.105.7.103

    authors: Pollock BE

    更新日期:2006-12-01 00:00:00

  • Multiple intracranial aneurysms due to Coccidioides immitis infection. Case report.

    abstract::True mycotic (fungal) aneurysms are distinctly uncommon. The case of a young woman with multiple intracranial aneurysms of Coccidioides immitis origin is presented. Coccidioides immitis organisms are not uncommon central nervous system pathogens and usually cause basilar meningitis and hydrocephalus. There are no prev...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1987.66.3.0453

    authors: Hadley MN,Martin NA,Spetzler RF,Johnson PC

    更新日期:1987-03-01 00:00:00

  • Indwelling double-balloon shunt for carotid endarterectomy. Technical note.

    abstract::The authors describe an indwelling intraluminal shunt for carotid endarterectomy. The device is equipped with balloons at both ends to prevent bleeding and to hold the tube in place. The design permits use of a small tube which facilitates insertion, and prevents intimal damage and limitation of exposure of arterial p...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.60.4.0861

    authors: Furui T,Hasuo M

    更新日期:1984-04-01 00:00:00