The pineal gland: anatomy, physiology, and clinical significance.

Abstract:

:Since the discovery of melatonin approximately 25 years ago, there has been intense study regarding the details of the structure and function of the pineal gland. This work is reviewed, with particular emphasis on those aspects of importance to human physiology and disease.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Erlich SS,Apuzzo ML

doi

10.3171/jns.1985.63.3.0321

subject

Has Abstract

pub_date

1985-09-01 00:00:00

pages

321-41

issue

3

eissn

0022-3085

issn

1933-0693

journal_volume

63

pub_type

杂志文章,评审
  • Current and novel practice of stereotactic radiosurgery.

    abstract::Stereotactic radiosurgery emerged as a neurosurgical discipline in order to utilize energy for the manipulation of brain or nerve tissue, with the goal of minimal access and safe and effective care of a spectrum of neurosurgical disorders. Perhaps no other branch of neurosurgery has been so disruptive across the entir...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/2019.2.JNS181712

    authors: Kondziolka D

    更新日期:2019-06-01 00:00:00

  • Unusual case of extradural choroid plexus papilloma of the sacral canal. Case report.

    abstract::An unusual case of a sacral, extradural choroid plexus papilloma involving the S1-3 level is described. This 50-year-old woman presented with a 4-month history of pain involving her right buttock, perineum, and leg. Contrast-enhanced magnetic resonance (MR) imaging of the spine revealed a well-defined, mildly enhancin...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/spi.2002.97.1.0102

    authors: Kurtkaya-Yapicier O,Scheithauer BW,Van Peteghem KP,Sawicki JE

    更新日期:2002-07-01 00:00:00

  • The effect of a PP2A inhibitor on the nuclear receptor corepressor pathway in glioma.

    abstract:OBJECT:Nuclear receptor corepressor (N-CoR) forms a complex that maintains neural stem cells in an undifferentiated state through transcriptional repression. Recently, it has been shown that N-CoR is overexpressed in glioblastoma multiforme (GBM) tumor stem cells and has a putative role in maintaining these cells in an...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2009.11.JNS091272

    authors: Lu J,Zhuang Z,Song DK,Mehta GU,Ikejiri B,Mushlin H,Park DM,Lonser RR

    更新日期:2010-08-01 00:00:00

  • Cavernous hemangioma of the orbit.

    abstract::The clinical and pathological data of 66 patients with orbital cavernous hemangioma are presented. This tumor occurs in females more frequently than in males, and has its peak incidence in early middle age. Visual disability results from a high degree of relative hyperopia or from optic-nerve compression. Postural or ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1979.51.2.0219

    authors: Harris GJ,Jakobiec FA

    更新日期:1979-08-01 00:00:00

  • A methodology for verification of radiotherapy dose calculation.

    abstract:OBJECT:A methodology for dosimetric verification of radiation therapy plans was developed and implemented. Dosimetric accuracy of clinically active intensity-modulated radiotherapy (IMRT) and intensity-modulated radiosurgery (IMRS) programs was assessed using this methodology. METHODS:The methodology included several ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2004.101.supplement 3.0356

    authors: Agazaryan N,Ullrich W,Lee SP,Solberg TD

    更新日期:2004-11-01 00:00:00

  • Effect of country or continent of treatment on outcome after aneurysmal subarachnoid hemorrhage. Clinical article.

    abstract:OBJECT:Prognostic factors for outcome after aneurysmal subarachnoid hemorrhage (SAH) include the clinical and pathological characteristics of the patient and hemorrhage as well as some aspects of treatment. Because treatment can vary between countries and continents, the authors used a large database of patients with S...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2008.10.JNS08184

    authors: Lipsman N,Tolentino J,Macdonald RL

    更新日期:2009-07-01 00:00:00

  • Clinical evaluation of flat-panel detector compared with multislice computed tomography in 65 patients with acute intracranial hemorrhage: initial results. Clinical article.

    abstract:OBJECT:The goal in this study was to compare flat-panel detector (FD) CT with multislice (MS) CT in the visualization of intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), intraventricular hemorrhage, and external ventricular drains (EVDs) to evaluate the diagnostic quality and limitations of the new FD CT ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2010.2.JNS091054

    authors: Struffert T,Eyupoglu IY,Huttner HB,Engelhorn T,Doelken M,Saake M,Ganslandt O,Doerfler A

    更新日期:2010-10-01 00:00:00

  • The second-generation eCLIPs Endovascular Clip System: initial experience.

    abstract::OBJECTIVE Treatment of wide-necked intracranial aneurysms is associated with higher recanalization and complication rates; however, the most commonly used methods are not specifically designed to work in bifurcation lesions. To address these issues, the authors describe the evolution in the design and use of the eCLIP...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,多中心研究

    doi:10.3171/2016.10.JNS161731

    authors: Chiu AH,De Vries J,O'Kelly CJ,Riina H,McDougall I,Tippett J,Wan M,de Oliveira Manoel AL,Marotta TR

    更新日期:2018-02-01 00:00:00

  • Racial phenotypes in moyamoya disease: a comparative analysis of clinical presentation and natural history in a single multiethnic cohort of 250 hemispheres.

    abstract:OBJECTIVE:The authors aimed to determine whether differences exist in presentation and natural history when comparing Asian patients with moyamoya disease (MMD) to those of other ethnicities in North America. METHODS:A database of 137 patients with MMD presenting to their institution between 1994 and 2015 was reviewed...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2019.7.JNS191507

    authors: Feghali J,Xu R,Yang W,Liew J,Tamargo RJ,Marsh EB,Huang J

    更新日期:2019-10-04 00:00:00

  • Dynamic telescopic craniotomy: a cadaveric study of a novel device and technique.

    abstract::OBJECT The authors assessed the feasibility of the dynamic decompressive craniotomy technique using a novel cranial fixation plate with a telescopic component. Following a craniotomy in human cadaver skulls, the telescopic plates were placed to cover the bur holes. The plates allow constrained outward movement of the ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2015.6.JNS15706

    authors: Khanna R,Ferrara L

    更新日期:2016-09-01 00:00:00

  • Assessment of necrotic core with intraplaque hemorrhage in atherosclerotic carotid artery plaque by MR imaging with 3D gradient-echo sequence in patients with high-grade stenosis. Clinical article.

    abstract:OBJECT:The aim of this study was to assess the histopathological differences between advanced atherosclerotic carotid artery (CA) plaques with signal hyperintensity on T1-weighted MR images and those without, focusing on necrotic core size and intraplaque hemorrhage (IPH). METHODS:Thirty-five patients scheduled for ca...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2010.3.JNS091057

    authors: Hishikawa T,Iihara K,Yamada N,Ishibashi-Ueda H,Miyamoto S

    更新日期:2010-10-01 00:00:00

  • The role of NLRP3 in traumatic brain injury and its regulation by pioglitazone.

    abstract:OBJECTIVE:Perilesional edema is a predominant mechanism underlying secondary brain injury after traumatic brain injury (TBI). Perilesional edema is characterized by inflammation, production of proinflammatory cytokines, and migration of peripheral immune cells into the brain. The nucleotide-binding domain and leucine-r...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2019.6.JNS1954

    authors: Yi HJ,Lee JE,Lee DH,Kim YI,Cho CB,Kim IS,Sung JH,Yang SH

    更新日期:2019-09-27 00:00:00

  • Intracranial pressure monitoring with the Neurodur-P epidural sensor: a prospective study in patients with adult hydrocephalus or idiopathic intracranial hypertension.

    abstract:OBJECT:Continuous intracranial pressure (ICP) monitoring using an epidural sensor is a common technique used in selected neurosurgical patients. The aim of this study was to assess the safety and accuracy of the Neurodur-P epidural sensor in the clinical setting. METHODS:The zero drift, as well as the medical and tech...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/JNS/2008/108/5/0934

    authors: Poca MA,Martínez-Ricarte F,Sahuquillo J,Lastra R,Torné R,Armengol MS

    更新日期:2008-05-01 00:00:00

  • Neuroimaging and pathological findings in a child with cerebral sparganosis. Case report.

    abstract::The authors report the case of a 6-year-old boy with cerebral sparganosis due to infection with a plerocercoid tapeworm larva of Spirometra mansoni. Magnetic resonance imaging revealed an area of irregular long T2 signal in the right frontal lobe. When compared with images obtained 2 years earlier, the lesion appeared...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2006.105.6.470

    authors: Bo G,Xuejian W

    更新日期:2006-12-01 00:00:00

  • Effect of slosh mitigation on histologic markers of traumatic brain injury: laboratory investigation.

    abstract:OBJECT:Helmets successfully prevent most cranial fractures and skull traumas, but traumatic brain injury (TBI) and concussions continue to occur with frightening frequency despite the widespread use of helmets on the athletic field and battlefield. Protection against such injury is needed. The object of this study was ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2012.8.JNS12358

    authors: Turner RC,Naser ZJ,Bailes JE,Smith DW,Fisher JA,Rosen CL

    更新日期:2012-12-01 00:00:00

  • Effect of fixed-setting versus programmable valve on incidence of shunt revision after ventricular shunting for idiopathic normal pressure hydrocephalus.

    abstract:OBJECTIVE:Although ventricular shunting is an effective therapy for idiopathic normal pressure hydrocephalus (iNPH), the effect of shunt valve type on the incidence of revision surgery is not well defined. To address this issue, shunt revision rates between patients with iNPH receiving a fixed-setting valve (FSV) versu...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2019.3.JNS183077

    authors: Rinaldo L,Bhargav AG,Nesvick CL,Lanzino G,Elder BD

    更新日期:2019-06-07 00:00:00

  • Endonasal endoscopic transsphenoidal resection of intrinsic third ventricular craniopharyngioma: surgical results.

    abstract::OBJECTIVEIntrinsic third ventricular craniopharyngiomas (IVCs) have been reported by some authors to "pose the greatest surgical challenge" of all craniopharyngiomas (CPAs). A variety of open microsurgical approaches have historically been used for resection of these tumors. Despite increased utilization of the endosc...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2018.5.JNS18198

    authors: Forbes JA,Ordóñez-Rubiano EG,Tomasiewicz HC,Banu MA,Younus I,Dobri GA,Phillips CD,Kacker A,Cisse B,Anand VK,Schwartz TH

    更新日期:2018-11-01 00:00:00

  • Spontaneous cerebellar hematoma associated with chronic cerebellar stimulation. Case report.

    abstract::A 24-year-old man developed a spontaneous cerebellar hematoma 5 years after the implantation of cerebellar electrodes. No vascular malformations were found either intraoperatively or radiographically. The histopathological findings of the cerebellar tissue obtained at biopsy from the region surrounding the electrodes ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1986.65.6.0860

    authors: Zuccarello M,Sawaya R,Lukin R,deCourten-Myers G

    更新日期:1986-12-01 00:00:00

  • Cognitive impairment and adjustment in patients without neurological deficits after aneurysmal SAH and early operation.

    abstract::The mortality rate has recently been reduced to only a small percentage of patients selected for early aneurysm surgery. Despite recovery without neurological deficits, however, a diffuse encephalopathy may remain, with emotional and psychological sequelae that will interfere with rehabilitation and social reintegrati...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1985.62.5.0673

    authors: Ljunggren B,Sonesson B,Säveland H,Brandt L

    更新日期:1985-05-01 00:00:00

  • Reduction of spinal cord injury by administration of iloprost, a stable prostacyclin analog.

    abstract::To investigate whether iloprost, a stable analog of prostacyclin, is useful for the prevention of posttraumatic spinal cord injury, we examined its effects on compression trauma-induced spinal cord injury in rats. Spinal cord injury was induced by applying a 20-g weight for 20 minutes to the spinal cord at the level o...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1997.86.6.1007

    authors: Taoka Y,Okajima K,Uchiba M,Murakami K,Harada N,Johno M,Naruo M,Okabe H,Takatsuki K

    更新日期:1997-06-01 00:00:00

  • Coccidioidomycotic brain abscess. Case report.

    abstract::Coccidioidomycosis is an infection originating in the San Joaquim Valley of southern California, but now seen with increasing frequency throughout southern California and the southwestern United States. Central nervous system involvement is usually manifested as meningitis. The authors present the case of a young man ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1994.80.1.0140

    authors: Mendel E,Milefchik EN,Ahmadi J,Gruen P

    更新日期:1994-01-01 00:00:00

  • Cavernous angioma of the geniculate ganglion.

    abstract::Intracranial extraaxial cavernous angiomas are rare vascular malformations. Their occurrence at the geniculate ganglion of the facial nerve within the temporal bone is exceptional. The authors describe a 35-year-old man who developed a slowly progressing facial palsy. Initial cranial MR imaging showed no pathological ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/JNS/2008/109/11/0893

    authors: Capelle HH,Nakamura M,Lenarz T,Brandis A,Haubitz B,Krauss JK

    更新日期:2008-11-01 00:00:00

  • Risk factors governing the development of cerebral vein and dural sinus thrombosis after craniotomy in patients with intracranial tumors.

    abstract::OBJECTIVE Neurosurgical intervention may increase the risk of developing cerebral vein and dural sinus thrombosis (CVT). The clinical management of CVT in postoperative patients remains unclear. This retrospective study explores the disease occurrence, associated risk factors, and outcomes in patients with tumors who ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2016.11.JNS161871

    authors: Gessler F,Bruder M,Duetzmann S,Tritt S,Bernstock JD,Seifert V,Senft C

    更新日期:2018-02-01 00:00:00

  • Choroid plexus papillomas: long-term follow-up results in a surgically treated series.

    abstract::The medical records and histological specimens from 26 patients with choroid plexus papillomas operated on at one institution were reviewed retrospectively. Four patients died perioperatively, and 21 of the remaining 22 patients were followed through March, 1986; the patient lost to follow-up review was last seen 14 y...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1988.69.6.0843

    authors: McGirr SJ,Ebersold MJ,Scheithauer BW,Quast LM,Shaw EG

    更新日期:1988-12-01 00:00:00

  • Symptomatic C1-2 fusion failure due to a fracture of the lateral C-1 posterior arch in a patient with rheumatoid arthritis. Case report and review of the literature.

    abstract::The authors report a case in which the lateral C-1 arch fractured in a patient with rheumatoid arthritis and an intact fusion mass; this patient had previously undergone a C1-2 Brooks-type fusion. This unique complication occurred secondary to continued resorption of the C1-2 rheumatoid pannus. Two years after occipit...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/spi.2001.94.1.0137

    authors: Ecker RD,Dekutoski MB,Ebersold MJ

    更新日期:2001-01-01 00:00:00

  • Spontaneous regression of a herniated cervical disc in a patient with myelopathy. Case report.

    abstract::The authors present a case of spontaneous regression of a herniated cervical nucleus pulposus in a patient with myelopathy. This 37-year-old woman developed sudden quadriparesis; she had reported no history of trauma. Magnetic resonance (MR) imaging revealed a large disc herniation and increased signal intensity of th...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/spi.1999.90.1.0138

    authors: Song JH,Park HK,Shin KM

    更新日期:1999-01-01 00:00:00

  • The use of clip-suture in thoracic sympathectomy. Technical note.

    abstract::A technique is described for using a clip-suture to expedite handling of the divided sympathetic chain in a deep, small upper-thoracic exposure. No late failures were experienced in 23 patients with hyperhydrosis surgically treated using this technique. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1994.81.3.0482

    authors: Beatty RA

    更新日期:1994-09-01 00:00:00

  • Modified stereotactic insertion of the Ommaya reservoir. Technical note.

    abstract::Ommaya reservoirs are used primarily for the repeated injection of intrathecal chemotherapy for leptomeningeal metastasis from hematopoietic and solid malignancies. Insertion of this device in a relatively large nondisplaced ventricle is not a difficult task, but challenges arise when the ventricle is small and/or dis...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2000.92.6.1050

    authors: Al-Anazi A,Bernstein M

    更新日期:2000-06-01 00:00:00

  • Synergistic effect of basic fibroblast growth factor and methylprednisolone on neurological function after experimental spinal cord injury.

    abstract::The authors evaluated the effects of exogenous basic fibroblast growth factor (bFGF) in combination with intravenous methylprednisolone on neurological function and cord angiogenesis in a model of spinal cord injury. Cord injury was produced by extradural clip compression through a T-1 laminectomy. Rats were randomize...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1995.83.1.0105

    authors: Baffour R,Achanta K,Kaufman J,Berman J,Garb JL,Rhee S,Friedmann P

    更新日期:1995-07-01 00:00:00

  • Phase I trial of caudate deep brain stimulation for treatment-resistant tinnitus.

    abstract:OBJECTIVE:The objective of this open-label, nonrandomized trial was to evaluate the efficacy and safety of bilateral caudate nucleus deep brain stimulation (DBS) for treatment-resistant tinnitus. METHODS:Six participants underwent DBS electrode implantation. One participant was removed from the study for suicidality u...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2019.4.JNS19347

    authors: Cheung SW,Racine CA,Henderson-Sabes J,Demopoulos C,Molinaro AM,Heath S,Nagarajan SS,Bourne AL,Rietcheck JE,Wang SS,Larson PS

    更新日期:2019-09-24 00:00:00