Production of experimental brain abscess in the rat.

Abstract:

:Experimental evaluation of brain abscess has been inhibited by the lack of a simple and reproducible model in small animals. A stereotaxic headholder and slow infusion of 1 microliter of saline, containing a known number of bacteria, were used to produce brain abscess consistently in the rat. The natural history of the brain abscess produced by this technique closely simulated that found in the human clinical situation.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Winn HR,Mendes M,Moore P,Wheeler C,Rodeheaver G

doi

10.3171/jns.1979.51.5.0685

subject

Has Abstract

pub_date

1979-11-01 00:00:00

pages

685-90

issue

5

eissn

0022-3085

issn

1933-0693

journal_volume

51

pub_type

杂志文章
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