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Alopecia in Children Following Living Related Liver Transplantation.

Abstract：

INTRODUCTION:Alopecia is a common complication in patients following kidney transplantation; however, reports regarding liver transplantation patients are still few. METHODS:This study followed 111 children who underwent living related liver transplantation. Alopecia patients and its possible risk factors were analyzed. RESULTS:Alopecia occurred in 3 patients (2.7%). Underlying diseases were biliary atresia and Alagille syndrome. Clinically significant alopecia (universal alopecia) occurred in 1 patient with Alagille syndrome. All patients received tacrolimus as their immunosuppression drug. None of the patients who received cyclosporine experienced alopecia. The onset of alopecia ranged from 7 to 28 months after transplantation. Alopecia was treated with a topical corticosteroid and topical tacrolimus, but 1 patient with clinically severe alopecia required conversion from tacrolimus to cyclosporine A. CONCLUSIONS:Alopecia is 1 complication seen in children receiving tacrolimus therapy following living donor liver transplant. Prompt management of this cosmetic complication should be done to ensure patients' compliance to medication regimen.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Alatas FS,Matsuura T,Yoshimaru K,Kadim M,Taguchi T

doi

10.1016/j.transproceed.2020.05.020

subject

Has Abstract

pub_date

2021-01-01 00:00:00

pages

228-232

issue

1

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(20)30152-4

journal_volume

53

pub_type

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