Abstract:
OBJECTIVE:This study aimed to describe end-of-life (EOL) care in individuals with bipolar disorder (BD) who died of cancer compared with mentally healthy individuals. METHODS:This was a nationwide cohort study of all adult individuals who died of cancer in hospitals in France between 2013 and 2016. Outcomes were compared between individuals with BD and mentally healthy individuals in the last month of life including palliative care and high-intensity EOL care (chemotherapy, artificial nutrition, and other interventions). A subanalysis explored differences between patients with BD and patients with schizophrenia. RESULTS:The study included 2015 individuals with BD and 222,477 mentally healthy controls. Compared with the controls, individuals with BD died 5 years earlier, more often had comorbidities and thoracic cancer, and had fewer metastases, but did not have shorter delays from cancer diagnosis to death. After matching and adjustment for covariates, individuals with BD more often received palliative care in the last 3 days of life (25% versus 13%, p < .001) and less high-intensity care (e.g., chemotherapy 12% versus 15%, p = .004), but more artificial nutrition (6% versus 4.6%, p = .003). Compared with the schizophrenia comparison group, chemotherapy was received more by individuals with BD in the last 14 days of life (12.5% for BD versus 9.4%, p < .001). CONCLUSIONS:Individuals with BD were more likely to receive palliative care and less likely to receive high-intensity EOL care, except for artificial nutrition. These results may not be specific to BD, as no difference was found between patients with BD and schizophrenia except for chemotherapy.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Fond G,Baumstarck K,Auquier P,Pauly V,Bernard C,Orleans V,Llorca PM,Lancon C,Salas S,Boyer Ldoi
10.1097/PSY.0000000000000839subject
Has Abstractpub_date
2020-09-01 00:00:00pages
722-732issue
7eissn
0033-3174issn
1534-7796journal_volume
82pub_type
杂志文章abstract:OBJECTIVES:To determine if: 1) depressed patients with a recent acute myocardial infarction (AMI) have higher nighttime heart rate (HR) than nondepressed patients, and 2) elevated nighttime HR is associated with decreased survival post AMI. Depression is a risk factor for mortality post AMI. It is also associated with ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181835ca3
更新日期:2008-09-01 00:00:00
abstract::In a study designed to identify the electrophysiologic characteristics of the Transcendental Meditation Program, 52 periods of spontaneous respiratory suspension (RS) were observed in 18 subjects during the practice of this program. These periods were correlated with some but not all the subjective experiences of pure...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198405000-00008
更新日期:1984-05-01 00:00:00
abstract::Two separate studies assessed the influence on menstrual distress and related inhibition of such variables as predictability of onset, dispositional susceptibility to cultural expectations, and the attentional focus provided by labels. Greater predictability of onset was associated with more positive feedlings about m...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197908000-00004
更新日期:1979-08-01 00:00:00
abstract::Recent technologic advances have permitted the observation of rapid and significant increases in blood pressure (BP) during verbal communication. The magnitude of the increase in BP is influenced by rate of speech, audience size, status, affective content, environmental setting, and resting BP. The current study evalu...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198601000-00008
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:Persons with elevated blood pressure (BP) show dampened emotional responses to affect-laden stimuli. We sought to further examine cardiovascular-emotional dampening by examination of the relationship between resting hemodynamic measures and recognition of emotion in an African American community-based sample....
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e318235ed55
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To test the reactivity hypothesis using blood pressure data collected 12 years after baseline. This study examined whether blood pressure reactions to acute mental stress predicted future blood pressure resting levels, as well as the temporal drift in resting blood pressure, and whether the prediction was aff...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182359808
更新日期:2011-11-01 00:00:00
abstract::The study of depression in cancer patients has been hampered by difficulty in establishing diagnostic criteria, since neurovegetative signs and symptoms may be attributable either to depression or physical illness. Confusion has also arisen in defining the boundary between "normal" grieving with illness, and "abnormal...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198405000-00002
更新日期:1984-05-01 00:00:00
abstract:OBJECTIVE:To assess the biological correlates of effort-reward imbalance and overcommitment to work using measurements over the working day. METHODS:Participants were 197 working men and women aged 45 to 59 years, recruited from the Whitehall II epidemiological cohort. Salivary cortisol was sampled on waking, 30 minut...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000126198.67070.72
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:Macrophage migration inhibitory factor (MIF), a protein secreted by immune cells and the pituitary gland, may be associated with coronary artery disease (CAD) and the mental state of coronary patients. The first origin of MIF suggests positive, the second negative associations. The aim of this study was to ex...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/PSY.0b013e31802b8750
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To describe factors influencing chest pain expression in patients with cardiac or noncardiac disease. METHODS:The authors conducted a case presentation and review of literature. RESULTS:Causes of chest pain are diverse. Psychologic factors influence chest pain expression commonly in patients with or without...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/01.psy.0000146330.80895.77
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:The influence of low socioeconomic status on cardiovascular disease may be mediated in part by sustained activation of stress-related autonomic and neuroendocrine processes. We hypothesized that low socioeconomic status would be associated with heightened ambulatory blood pressure and cortisol output over th...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000035717.78650.a1
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVES:To hypothesize in a new and different population that administrative database (ADB) screening would identify somatizing patients by increasing numbers of visits, female gender, and greater percent of International Classification of Diseases, 9th Edition (ICD-9) primary diagnosis codes in musculoskeletal, ner...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31819cc783
更新日期:2009-04-01 00:00:00
abstract::Seventy-two healthy males were divided into Type A and Type B groups using the Jenkins Activity Survey. Subjects were subdivided further into high and low self-awareness categories on the private self-consciousness factor of the Self-Consciousness Scale. After random assignment to consume alcohol (0.85 g/kg) or a plac...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006842-198807000-00005
更新日期:1988-07-01 00:00:00
abstract::Twenty young male coffee-drinkers consumed 150 mg of caffeine in decaffeinated coffee three times a day for 8 days. On days 3, 4, 7, and 8, caffeine or a placebo was administered in the laboratory at 11 A.M., 8 A.M., 11 A.M., and 8 A.M., respectively, in a randomized double-blind crossover design. There was a blood pr...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006842-199005000-00007
更新日期:1990-05-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to describe the sequence of psychosocial events and infections preceding the onset of chronic fatigue syndrome (CFS). This information was related to the temporal development of crucial symptoms in relation to the onset of, namely, fatigue, sadness, irritability, pain, and feelin...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199905000-00009
更新日期:1999-05-01 00:00:00
abstract::Depression is a well-known reaction to separation in all species of macaques studied except the bonnet (M. radiata), in whom this reaction has never before been observed. We have produced the depressive response of postural collapse and social withdrawal in a bonnet infant by altering the social structure of the group...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197802000-00008
更新日期:1978-02-01 00:00:00
abstract:OBJECTIVE:Numerous theories have proposed that acute and chronic stressors may exert a cumulative effect on life-span health by causing biological "wear and tear," or allostatic load, which in turn promotes disease. Very few studies have directly tested such models, though, partly because of the challenges associated w...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000534
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:Our objectives were to test whether Conscientiousness, the other 4 domains of the Five-Factor Model, and their facets predicted mortality in older, frail individuals. METHODS:Controlling for demographic and health measures, we used Cox regression to test whether the NEO Five-Factor Inventory (NEO-FFI) Neuro...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000181272.58103.18
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:Although the association between major depressive disorder (MDD) and future cardiovascular disease (CVD) is established, less is known about the relationship between CVD risk factors and future depression, and no studies have examined MDD subtypes. Our objective was to determine whether hypertension, tobacco ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000583
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:Depression and anxiety are considered risk factors for cardiovascular disease (CVD). The explanatory mechanisms, however, are still to be characterized. One proposed pathophysiological pathway is dysregulation of the autonomic nervous system, including heightened sympathetic nervous system activity. This stud...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000144
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:Little is known about how patients who seek medical help for benign palpitations can be distinguished from those with clinically significant arrhythmias. This study tested whether patients with arrhythmia can be distinguished from those who are aware of sinus rhythm or extrasystoles on the basis of sex, preva...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-200009000-00014
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:This study aimed to examine associations among race, the accumulation of multiple forms of discriminatory experiences (i.e., "pervasive discrimination"), and allostatic load (AL) in African Americans and whites in midlife. METHODS:Using data collected in 2004 to 2006 from 226 African American and 978 white a...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000788
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:Somatic symptom disorder (SSD) often co-occurs with major depressive disorder (MDD). Both conditions share common psychobiological and biobehavioral characteristics, but little is known about differential patterns in brain function. In this study, we compared resting-state functional brain connectivity betwee...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000490
更新日期:2017-11-01 00:00:00
abstract::Growth of syngeneic P815 mastocytoma in DBA/2J male mice was evaluated following social and physical stress exposure. Although social isolation following tumor cell transplantation enhanced tumor growth, it appeared that it was the abrupt change in social conditions, rather than the isolation per se which was responsi...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198005000-00005
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVE:We investigated whether perception of subjective asthma symptoms can be brought under control of biomedically irrelevant cues in the environment, i.e., whether subjective asthma symptoms can be learned in response to harmless stimuli. METHODS:Twenty patients with asthma and 20 healthy participants were prese...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000160470.43167.e2
更新日期:2005-05-01 00:00:00
abstract::Semantics and history of psychosomatic medicine are not popular topics nowadays, if they ever were; yet both of them constitute indispensable facets of any discipline that lays claim to a separate identity, as psychosomatics does. The latter, being an inchoate and inherently complex field of study, is especially in ne...
journal_title:Psychosomatic medicine
pub_type: 历史文章,杂志文章
doi:10.1097/00006842-198403000-00007
更新日期:1984-03-01 00:00:00
abstract:OBJECTIVE:To examine the potential moderating role of DRD2 polymorphism (rs1800497) in the association between stressful life events and depressive symptoms among young adults. Although stressful life events, such as divorce, unemployment, and serious illness in the family, are generally associated with negative health...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/psy.0b013e31806bf365
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:Acute myocardial infarction is often accompanied by anxiety, but the effect of this emotion on recovery is unclear. The purpose of this study was to determine the association between patient anxiety early after acute myocardial infarction and the incidence of subsequent in-hospital complications. METHODS:We ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/00006842-199609000-00001
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVES:Beyond male/female binaries, gender roles represent masculine and feminine traits that we assimilate and enact throughout life span development. Bem proposed that "androgynous" individuals adeptly adapt to different contexts by alternating from a strong repertoire of both masculine and feminine gender roles....
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000351
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVES:Research suggests that individuals with posttraumatic stress disorder (PTSD) are more likely to develop medical conditions and other stress-related psychiatric disorders. Given these findings and others suggesting that PTSD victims may have altered neuroendocrine and immune systems, the hypothesis that Vietn...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章
doi:10.1097/00006842-199905000-00019
更新日期:1999-05-01 00:00:00