Cardiovascular Risk Factors as Differential Predictors of Incident Atypical and Typical Major Depressive Disorder in US Adults.

Abstract:

OBJECTIVE:Although the association between major depressive disorder (MDD) and future cardiovascular disease (CVD) is established, less is known about the relationship between CVD risk factors and future depression, and no studies have examined MDD subtypes. Our objective was to determine whether hypertension, tobacco use, and body mass index (BMI) differentially predict atypical and typical MDD in a national sample of US adults. METHODS:We examined prospective data from 22,915 adults with no depressive disorder history at baseline who participated in Wave 1 (2001-2002) and Wave 2 (2004-2005) of the National Epidemiologic Survey on Alcohol and Related Conditions. CVD risk factors (Wave 1) and incident MDD subtypes (Wave 2) were determined by structured interviews. RESULTS:There were 252 patients with atypical MDD and 991 patients with typical MDD. In fully adjusted models, baseline hypertension (odds ratio [OR] = 0.57, 95% confidence interval [CI] = 0.43-0.76), former tobacco use (OR = 1.46, 95% CI = 1.20-1.78), and BMI (OR = 1.32, 95% CI = 1.25-1.40; all p < .001) predicted incident atypical MDD versus no MDD, whereas no CVD risk factor predicted incident typical MDD. Baseline hypertension (OR = 0.52, 95% CI = 0.39-0.70), former tobacco use (OR = 1.53, 95% CI = 1.22-1.93), and BMI (OR = 1.26, 95% CI = 1.18-1.36; all p < .001) also predicted incident atypical MDD versus typical MDD. CONCLUSIONS:Our study is the first to report that CVD risk factors differentially predict MDD subtypes, with hypertension (protective factor), former tobacco use (risk factor), and BMI (risk factor) being stronger predictors of incident atypical versus typical MDD. Such evidence could provide insights into the etiologies of MDD subtypes and inform interventions tailored to MDD subtype.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Patel JS,Berntson J,Polanka BM,Stewart JC

doi

10.1097/PSY.0000000000000583

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

508-514

issue

6

eissn

0033-3174

issn

1534-7796

journal_volume

80

pub_type

杂志文章
  • Altruistic social interest behaviors are associated with better mental health.

    abstract:OBJECTIVE:This study investigated whether altruistic social interest behaviors such as engaging in helping others were associated with better physical and mental health in a stratified random sample of 2016 members of the Presbyterian Church throughout the United States. METHODS:Mailed questionnaires evaluated giving ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000079378.39062.d4

    authors: Schwartz C,Meisenhelder JB,Ma Y,Reed G

    更新日期:2003-09-01 00:00:00

  • Intervention for minor depression in primary care patients.

    abstract::This study examines the effectiveness of an intervention for minor depression in primary care patients. One hundred fifty public care medical patients were randomly assigned to either an 8-week cognitive-behavioral course intended to help them use pleasant activities, constructive thinking, and interpersonal relations...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199403000-00009

    authors: Miranda J,Muñoz R

    更新日期:1994-03-01 00:00:00

  • Aerobic fitness level and reactivity to psychosocial stress: physiological, biochemical, and subjective measures.

    abstract::Aerobic fitness is associated with numerous physiological adaptations which permit physical stress to be coped with more efficiently. The present experiment examined whether aerobic fitness influences emotional response. Heart rate, biochemical measures (catecholamines, cortisol, prolactin, lactic acid), and self-repo...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198306000-00003

    authors: Sinyor D,Schwartz SG,Peronnet F,Brisson G,Seraganian P

    更新日期:1983-06-01 00:00:00

  • Depressed mood and other psychiatric manifestations of Cushing's syndrome: relationship to hormone levels.

    abstract::Thirty-five consecutive patients with Cushing's syndrome were studied prospectively prior to treatment. A consistent constellation of psychiatric disturbances was found, including impairments in affect (depressed mood and crying), cognitive functions (decreased concentration and memory), and vegetative functions (decr...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198102000-00002

    authors: Starkman MN,Schteingart DE,Schork MA

    更新日期:1981-02-01 00:00:00

  • Diagnostic groups and depressed mood as predictors of 22-month mortality in medical inpatients.

    abstract:OBJECTIVE:While depression has been found to predict mortality in acute myocardial infarction, results from many other groups of medical patients are inconclusive. It is, therefore, unclear whether depression also predicts mortality in the typical mixed patient populations treated on medical hospital wards and whether ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199809000-00011

    authors: Herrmann C,Brand-Driehorst S,Kaminsky B,Leibing E,Staats H,Rüger U

    更新日期:1998-09-01 00:00:00

  • Another Step Toward Clarifying the Benefits and Burdens of Selective Serotonin Reuptake Inhibitors.

    abstract::Selective serotonin reuptake inhibitors (SSRIs) have substantial beneficial effects for the treatment of major depressive mood disorders and other conditions but can also result in unwanted clinical outcomes. One of the reported disadvantages of SSRIs, based on cross-sectional studies, is their adverse effects on glyc...

    journal_title:Psychosomatic medicine

    pub_type: 评论,社论

    doi:10.1097/PSY.0000000000000735

    authors: Wulsin LR

    更新日期:2019-09-01 00:00:00

  • Smoking status and nicotine administration differentially modify hemodynamic stress reactivity in men and women.

    abstract:OBJECTIVES:To investigate the impact of cigarette smoking and oral contraceptive (OC) use on hemodynamic stress responses of women. Also, to examine gender differences in stress reactivity as a function of smoking status and acute nicotine administration. METHODS:Thirty men and 46 women, differing in smoking status an...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199705000-00012

    authors: Girdler SS,Jamner LD,Jarvik M,Soles JR,Shapiro D

    更新日期:1997-05-01 00:00:00

  • It's more than sex: exploring the dyadic nature of sleep and implications for health.

    abstract::Sleep is a critical health behavior and one that is typically shared between husbands and wives or romantic partners. However, the science of sleep has traditionally conceptualized and evaluated sleep at the level of the individual. Considering the social context of sleep represents a significant shift in sleep resear...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/PSY.0b013e3181de7ff8

    authors: Troxel WM

    更新日期:2010-07-01 00:00:00

  • Sleep disorder and psychobiological symptomatology in male psychiatric outpatients and male nonpatients.

    abstract::Sleep disturbance was studied in relation to psychiatric and physical symptoms for 214 male psychiatric outpatients and 248 male nonpatients. Our self-report instrument required that subjects describe the frequency of symptoms precisely on a five-point scale from "every day" to "not at all." Percentages are based on t...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197611000-00002

    authors: Sweetwood HL,Kripke DF,Grant I,Yager J,Gerst MS

    更新日期:1976-11-01 00:00:00

  • Chronic interpersonal stress predicts activation of pro- and anti-inflammatory signaling pathways 6 months later.

    abstract:OBJECTIVE:To understand the mechanisms underlying chronic interpersonal difficulties and their detrimental influence on mental and physical health. METHODS:A total of 103 healthy young women (mean age = 17 years) were administered a structured interview to assess the degree of chronic interpersonal stress in their liv...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e318190d7de

    authors: Miller GE,Rohleder N,Cole SW

    更新日期:2009-01-01 00:00:00

  • Classical conditioning of insulin effects in healthy humans.

    abstract:OBJECTIVE:Classical conditioning of insulin effects was examined in healthy humans using a placebo-controlled design. This study examined whether subjects who experienced a conditioned stimulus (CS) paired with insulin in the acquisition phase of a conditioning protocol would show a conditioned decrease of blood glucos...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199907000-00004

    authors: Stockhorst U,Gritzmann E,Klopp K,Schottenfeld-Naor Y,Hübinger A,Berresheim HW,Steingrüber HJ,Gries FA

    更新日期:1999-07-01 00:00:00

  • Impaired central processing of emotional faces in anorexia nervosa.

    abstract:OBJECTIVES:To elucidate the potential relationship between classification of emotional faces and impaired central processing in eating disorders and to investigate the potential mediatory role of alexithymia and depression in this relationship. METHODS:Visual-evoked potentials (VEPs) to emotional faces and classificat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31817e41e6

    authors: Pollatos O,Herbert BM,Schandry R,Gramann K

    更新日期:2008-07-01 00:00:00

  • Association of depressive and anxiety symptoms with 24-hour urinary catecholamines in individuals with untreated high blood pressure.

    abstract:OBJECTIVE:Depression and anxiety are considered risk factors for cardiovascular disease (CVD). The explanatory mechanisms, however, are still to be characterized. One proposed pathophysiological pathway is dysregulation of the autonomic nervous system, including heightened sympathetic nervous system activity. This stud...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000144

    authors: Paine NJ,Watkins LL,Blumenthal JA,Kuhn CM,Sherwood A

    更新日期:2015-02-01 00:00:00

  • Psychomotor coordination and intelligence in childhood and health in adulthood--testing the system integrity hypothesis.

    abstract:OBJECTIVES:To examine associations between intelligence and psychomotor coordination in childhood and risk of psychological distress, poorer self-rated health, and obesity in adulthood. To investigate whether psychomotor coordination as a potential marker of the construct "system integrity" explains associations betwee...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181a63b2e

    authors: Gale CR,Batty GD,Cooper C,Deary IJ

    更新日期:2009-07-01 00:00:00

  • Critical life events, infections, and symptoms during the year preceding chronic fatigue syndrome (CFS): an examination of CFS patients and subjects with a nonspecific life crisis.

    abstract:OBJECTIVE:The purpose of this study was to describe the sequence of psychosocial events and infections preceding the onset of chronic fatigue syndrome (CFS). This information was related to the temporal development of crucial symptoms in relation to the onset of, namely, fatigue, sadness, irritability, pain, and feelin...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199905000-00009

    authors: Theorell T,Blomkvist V,Lindh G,Evengård B

    更新日期:1999-05-01 00:00:00

  • Parental history of hypertension and coping responses predict blood pressure changes in black college volunteers undergoing a speaking task about perceptions of racism.

    abstract:OBJECTIVE:This investigation explored the relationship of coping responses and parental history of hypertension to task-induced blood pressure changes. MATERIALS AND METHODS:The sample consisted of 215 black college student volunteers (median age = 25.95 y). During the speaking task, participants responded to standard...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000097331.10458.f1

    authors: Clark R

    更新日期:2003-11-01 00:00:00

  • Telecommunications technology as an aid to family caregivers of persons with dementia.

    abstract:OBJECTIVE:The aging of the population implies that an increased number of people are going to need some form of care or assistance. Caregiving poses a range of physical, emotional, and financial demands and often causes burden and stress for family members. This article describes how technology can be used to provide s...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-200205000-00011

    authors: Czaja SJ,Rubert MP

    更新日期:2002-05-01 00:00:00

  • Socioeconomic status, antioxidant micronutrients, and correlates of oxidative damage: the Coronary Artery Risk Development in Young Adults (CARDIA) study.

    abstract:OBJECTIVE:To examine whether socioeconomic status (SES) (education, occupation, income), is associated both cross sectionally and prospectively with circulating concentrations of a) two correlates of oxidative damage, F(2)-isoprostanes (F(2)-IsoPs) and gamma-glutamyltransferase (GGT); and b) antioxidant nutrients (asco...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31819e7526

    authors: Janicki-Deverts D,Cohen S,Matthews KA,Gross MD,Jacobs DR Jr

    更新日期:2009-06-01 00:00:00

  • Domain and facet personality predictors of all-cause mortality among Medicare patients aged 65 to 100.

    abstract:OBJECTIVES:Our objectives were to test whether Conscientiousness, the other 4 domains of the Five-Factor Model, and their facets predicted mortality in older, frail individuals. METHODS:Controlling for demographic and health measures, we used Cox regression to test whether the NEO Five-Factor Inventory (NEO-FFI) Neuro...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000181272.58103.18

    authors: Weiss A,Costa PT Jr

    更新日期:2005-09-01 00:00:00

  • Depressed mood and flow-mediated dilation: a systematic review and meta-analysis.

    abstract:OBJECTIVE:This systematic and quantitative review evaluates the literature on associations between depressed mood and flow-mediated dilation (FMD), a measure of endothelial function, in adults. METHODS:Published English-language articles (through December 2010) were identified from literature searches, assessed for da...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/PSY.0b013e31821db79a

    authors: Cooper DC,Tomfohr LM,Milic MS,Natarajan L,Bardwell WA,Ziegler MG,Dimsdale JE

    更新日期:2011-06-01 00:00:00

  • Classic conditioning and dysfunctional cognitions in patients with panic disorder and agoraphobia treated with an implantable cardioverter/defibrillator.

    abstract:OBJECTIVE:A model for the development of anxiety disorders (panic disorder with or without agoraphobia) is needed. Patients with an implantable cardioverter/defibrillator (ICD) are exposed to repeated electric shocks. If the theory of anxiety development by aversive classic conditioning processes is valid, these repeat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-200103000-00006

    authors: Godemann F,Ahrens B,Behrens S,Berthold R,Gandor C,Lampe F,Linden M

    更新日期:2001-03-01 00:00:00

  • Linguistic Agency and Life-Span Longevity.

    abstract:OBJECTIVES:Agency has been conceptualized as a drive toward mastery, control, and effective self-management. Such an agentic approach to life and its challenges may be life-prolonging, a hypothesis not previously investigated. METHOD:In four studies, individual differences in agency were assessed in terms of the frequ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000337

    authors: Robinson MD,Bair JL,Persich MR,Moen NR

    更新日期:2016-09-01 00:00:00

  • Depression can be induced in a bonnet macaque infant.

    abstract::Depression is a well-known reaction to separation in all species of macaques studied except the bonnet (M. radiata), in whom this reaction has never before been observed. We have produced the depressive response of postural collapse and social withdrawal in a bonnet infant by altering the social structure of the group...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197802000-00008

    authors: Kaufman IC,Stynes AJ

    更新日期:1978-02-01 00:00:00

  • Does anxiety affect risk of dementia? Findings from the Caerphilly Prospective Study.

    abstract:OBJECTIVE:To examine the association of anxiety with incident dementia and cognitive impairment not dementia (CIND). METHODS:We conducted a prospective study of men aged 48 to 67 years at baseline anxiety assessment; we measured cognition 17 years later. We studied 1481 men who were either eligible for examination or ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181a6177c

    authors: Gallacher J,Bayer A,Fish M,Pickering J,Pedro S,Dunstan F,Ebrahim S,Ben-Shlomo Y

    更新日期:2009-07-01 00:00:00

  • Globus sensation and psychopathology in men: the Vietnam experience study.

    abstract:OBJECTIVE:To assess whether globus is associated with psychopathology in men. Globus-a persistent sensation of having a lump in the throat with no detectable physical cause-has long been thought a predominantly female disorder. Several small studies, based wholly or largely on women, suggested that globus is associated...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181bc7739

    authors: Gale CR,Wilson JA,Deary IJ

    更新日期:2009-11-01 00:00:00

  • Compliance with saliva sampling protocols: electronic monitoring reveals invalid cortisol daytime profiles in noncompliant subjects.

    abstract:OBJECTIVE:Ambulatory saliva collections for subsequent analysis of free cortisol levels are now frequently applied to measure adrenocortical activity in healthy subjects and patient populations. Despite the prime importance of accurate timing of saliva collection outside the laboratory, no data are available on the com...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000058374.50240.bf

    authors: Kudielka BM,Broderick JE,Kirschbaum C

    更新日期:2003-03-01 00:00:00

  • Tetrahydrocortisol/tetrahydrocortisone ratio (H4F/H4E) as an indicator of depressive feelings.

    abstract::Tetrahydrocortisol (H4F) and tetrahydrocortisone (H4E) were determined for a group of 15 depressed patients and 25 normal controls following the administration of cortisol-4-C14. The ratio, H4F/H4E, was significantly greater for the depressed patients than for the normal controls (P less than 0.001), although the sum ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197601000-00003

    authors: Persky H

    更新日期:1976-01-01 00:00:00

  • Cortisol excretion during the defense reaction in humans.

    abstract::Twelve subjects with specific phobias were exposed to slides with a phobic or a neutral content while cortisol excretion, electrodermal activity, and distress-ratings were studied. Six subjects fearful of blood and mutilation, and six of snakes or spiders, were presented with two sets of ten different slides (phobic o...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198507000-00001

    authors: Fredrikson M,Sundin O,Frankenhaeuser M

    更新日期:1985-07-01 00:00:00

  • Hostility is associated with visceral, but not subcutaneous, fat in middle-aged African American and white women.

    abstract:OBJECTIVE:To examine the cross-sectional association between hostility and measures of abdominal fat (visceral, subcutaneous) in middle-aged African American and white women. Because fat-patterning characteristics are known to differ by race, we were particularly interested in examining whether these associations were ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181ad13a7

    authors: Lewis TT,Everson-Rose SA,Karavolos K,Janssen I,Wesley D,Powell LH

    更新日期:2009-09-01 00:00:00

  • Neuroticism and cardiovascular disease mortality: socioeconomic status modifies the risk in women (UK Health and Lifestyle Survey).

    abstract:OBJECTIVE:The association between personality traits and mortality might differ as a function of socioeconomic status (SES). Our aim was to evaluate the all-cause, cardiovascular disease (CVD), and cancer mortality risk associated with neuroticism or extraversion and their interactions with SES in a representative samp...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31825c85ca

    authors: Hagger-Johnson G,Roberts B,Boniface D,Sabia S,Batty GD,Elbaz A,Singh-Manoux A,Deary IJ

    更新日期:2012-07-01 00:00:00