Abstract:
OBJECTIVE:Somatic symptom disorder (SSD) often co-occurs with major depressive disorder (MDD). Both conditions share common psychobiological and biobehavioral characteristics, but little is known about differential patterns in brain function. In this study, we compared resting-state functional brain connectivity between SSD and MDD using quantitative electroencephalography. METHODS:Fifteen patients with SSD (SSD group), 15 patients with MDD (MDD group), and 15 healthy volunteers (healthy control [HC] group) participated in this study. Participants were assessed with quantitative electroencephalography using a 21-channel electroencephalogram system. Electroencephalogram coherence in the theta frequency range (3.5-7.5 Hz) was assessed between the following seven electrode pairs: Fp1 and Fp2, F7 and T3, F8 and T4, T5 and P3, P4 and T6, P3 and Pz, and Pz and P4. Differences in coherence between groups were analyzed using analysis of variance. RESULTS:Theta coherence between the F7 and T3 electrodes was lower in the SSD group than the MDD and HC groups (F(2,42) = 6.67, p = .0030). Theta coherence between the T5 and P3 electrodes was lower in the SSD and MDD groups than the HC group (F(2,42) = 5.65, p = .0067). Theta coherence between the Pz and P4 electrodes was lower in the SSD group than the MDD group (F(2,42) = 6.41, p = .0037). CONCLUSIONS:Both SSD and MDD patients commonly showed decreased functional connectivity within the left temporoparietal junction, which has neurophysiological implications for cognitive-attentional processing and social interaction. Frontostriatal circuit dysfunction affects processes that control perception and emotion, as well as misperception of somatosensory data in the parietal somatosensory area, and is more likely to be a neuropathology of SSD than MDD.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Ahn J,Han DH,Hong JS,Min KJ,Lee YS,Hahm BJ,Kim SMdoi
10.1097/PSY.0000000000000490subject
Has Abstractpub_date
2017-11-01 00:00:00pages
982-987issue
9eissn
0033-3174issn
1534-7796journal_volume
79pub_type
杂志文章abstract::A general population sample of 100 primigravid women was studied prospectively to describe the changes in eating that occur in pregnancy with particular reference to cravings and aversions and the behavior and attitudes characteristic of clinical eating disorders. Assessment was by standardized interview. Dietary crav...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199211000-00006
更新日期:1992-11-01 00:00:00
abstract::This investigation assessed the syndromal nature of menstrual cycle changes in women who experience significant cyclicity of mood by exploring the time course of different symptoms in relation to endocrinologically defined segments of the menstrual cycle. Participants were accepted into the protocol on the basis of a ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198903000-00007
更新日期:1989-03-01 00:00:00
abstract::The prevalence of essential hypertension is higher among blacks than whites. One reason for this difference may be that blacks are more reactive to stressors that produce vasoconstrictive responses. Two studies were conducted to test this hypothesis, one with 10- to 14-year-old males (20 whites, 20 blacks) and one wit...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199005000-00003
更新日期:1990-05-01 00:00:00
abstract:OBJECTIVE:In this case study, we describe the effects of a particular individual's concentration/meditation technique on autonomic nervous system activity and the innate immune response. The study participant holds several world records with regard to tolerating extreme cold and claims that he can influence his autonom...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182583c6d
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:Trauma is associated with increased risk for anxiety disorders such as posttraumatic stress disorder (PTSD). To further understand biologic mechanisms of PTSD, we examined the dark-enhanced startle response, a psychophysiological correlate of anxiety, and heart rate variability (HRV) in traumatized individual...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e318240803a
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:Brain-gut-microbiota interactions may play an important role in human health and behavior. Although rodent models have demonstrated effects of the gut microbiota on emotional, nociceptive, and social behaviors, there is little translational human evidence to date. In this study, we identify brain and behavior...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000493
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:To examine the association between personality traits and longevity. METHODS:Using the Guilford-Zimmerman Temperament Survey, personality traits were assessed in 2359 participants (38% women; age = 17 to 98 years, mean = 50 years) from the Baltimore Longitudinal Study of Aging, starting in 1958. Over the dur...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31817b9371
更新日期:2008-07-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/PSY.0b013e31823d38bc
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:Persons with elevated blood pressure (BP) show dampened emotional responses to affect-laden stimuli. We sought to further examine cardiovascular-emotional dampening by examination of the relationship between resting hemodynamic measures and recognition of emotion in an African American community-based sample....
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e318235ed55
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To examine the hypothesis that young adults with major depressive disorder (MDD) would show increased affective bias to painful and nonpainful experimental heat stimuli, as evidenced by an increased responsiveness to warm and hot temperatures. Pain and depression often occur together. Pain is both a sensation...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181656a48
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:Although considerable evidence implicates hostility in the development of coronary artery disease (CAD), the pathogenic mechanisms remain poorly understood. We have developed a psychophysiological model that holds that altered autonomic nervous system function links psychological traits with CAD outcomes. In ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-200105000-00012
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate the construct validity of the five-item Women's Health Initiative Insomnia Rating Scale (WHIIRS) by comparing women taking hormone therapy (HT) versus those taking a placebo and by comparing women known to differ in vasomotor symptoms. METHODS:The WHIIRS was includ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/01.psy.0000151743.58067.f0
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVES:The two objectives are to test the hypothesis that women in a profession with low decision latitude will have greater catecholamine excretion and higher blood pressure than women in a profession with greater decision latitude, and to assess the influence of ethnicity on the occupational comparison. METHODS:...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000222356.71315.8e
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:To assess whether work characteristics and social support are predictors of physical, psychological, and social functioning. METHOD:Work characteristics (Karasek and Siegrist models) and social support at baseline were used to predict health functioning measured by the SF-36 General Health Survey 5 years lat...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199805000-00004
更新日期:1998-05-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000609
更新日期:2018-11-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000024235.11538.9a
更新日期:2002-09-01 00:00:00
abstract::This study's purpose was to examine the extent to which optimism, knowledge, attitudes, and beliefs predict use of HIV testing services in a group of at-risk female adolescents. We prospectively interviewed 124 consecutive girls engaging in risky behaviors before regularly scheduled pediatric clinic appointments at a ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199511000-00006
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVE:While depression has been found to predict mortality in acute myocardial infarction, results from many other groups of medical patients are inconclusive. It is, therefore, unclear whether depression also predicts mortality in the typical mixed patient populations treated on medical hospital wards and whether ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199809000-00011
更新日期:1998-09-01 00:00:00
abstract::Three studies on the relationship between life stresses and premature labor were conducted. The first was a retrospective comparison of life events between a group of women who had had premature labor and a group of controls. It was carried out between 3 and 6 months after the premature delivery to neutralize possible...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198605000-00006
更新日期:1986-05-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199905000-00009
更新日期:1999-05-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199107000-00003
更新日期:1991-07-01 00:00:00
abstract::Previous studies have identified the MMPI-based Cook and Medley hostility scale (Ho) as a predictor of health outcomes. To achieve a better understanding of the construct measured by this scale, Ho items were classified on an a priori basis. Six subsets were identified: Cynicism, Hostile Attributions, Hostile Affect, ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198901000-00005
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:Previous research demonstrated that social environment can influence progression of atherosclerosis in the Watanabe Heritable Hyperlipidemic (WHHL) rabbit. This study examined the effect of social environment on markers of oxidative stress and inflammation to clarify the physiological pathways potentially res...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181646753
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:To assess the relationship among Type D personality, self-efficacy, and medication adherence in patients with coronary heart disease. METHODS:The study design was prospective and observational. Type D personality, self-efficacy for illness management behaviors, and medication adherence were measured 3 weeks ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31823a5b2f
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:This investigation explored the relationship of coping responses and parental history of hypertension to task-induced blood pressure changes. MATERIALS AND METHODS:The sample consisted of 215 black college student volunteers (median age = 25.95 y). During the speaking task, participants responded to standard...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000097331.10458.f1
更新日期:2003-11-01 00:00:00
abstract::The association of peripheral arterial disease (PAD) with hostility, a component of Type A behavior, has not been investigated. Previous studies have found an association between coronary arterial disease and hostility. We used Doppler tests to define PAD as consisting of a resting index less than 0.9, absence of post...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198905000-00003
更新日期:1989-05-01 00:00:00
abstract::Thirty adults willing their body at death to medical science were compared on a number of personality variables with 30 nondonors, both groups equated for age, education, and socioeconomic status. Donors are internally directed, masters of their fate; nondonors rely on chance or luck to explain outcome. A more defin...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197507000-00004
更新日期:1975-07-01 00:00:00
abstract:OBJECTIVES:African Americans are characterized by higher heart rate variability (HRV), a finding ostensibly associated with beneficial health outcomes. However, these findings are at odds with other evidence that blacks have worse cardiovascular outcomes. Here, we examine associations in a large cohort from the ELSA-Br...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000359
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To determine whether the relationship between interleukin (IL)-6 and depressive symptoms is moderated by participation in moderate-intensity physical activity in a sample of primary care patients. Elevated inflammation has been associated with a number of poor health outcomes. Depressive symptoms may be relat...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182108412
更新日期:2011-04-01 00:00:00
abstract::Rats with a genetic susceptibility to experimental hypertension were exposed daily for 13 weeks to a conflict situation that resulted in food deprivation and the application of electric shock. Other subjects were either food deprived, shocked, both food deprived and shocked but without conflict, or not experimentally ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197509000-00004
更新日期:1975-09-01 00:00:00