Abstract:
OBJECTIVE:Macrophage migration inhibitory factor (MIF), a protein secreted by immune cells and the pituitary gland, may be associated with coronary artery disease (CAD) and the mental state of coronary patients. The first origin of MIF suggests positive, the second negative associations. The aim of this study was to explore the direction of the association of MIF with CAD and of MIF with exhaustion, if any. METHODS:Participants were 194 patients who had been recently treated by percutaneous coronary intervention (PCI) and who were exhausted at the start of the study. Half entered a behavioral intervention program. MIF, C-reactive protein, interleukin (IL)-6, IL-1 receptor antagonist, and neopterin were measured in blood collected 6 weeks after PCI (baseline) and 6 and 18 months after baseline. A single measurement of MIF was also available for 129 age- and sex-matched healthy individuals (reference group). RESULTS:At baseline, MIF in patients undergoing PCI was significantly lower than in the reference group (p < .01). New cardiac events occurred twice as often in the lowest quartile than in the highest quartile of MIF concentrations. However, the association was not significant (chi(2) = 2.27; df = 3; p = .52). During follow up, MIF concentrations increased significantly in patients undergoing PCI (p < .001). At 18 months, MIF concentrations were significantly lower in the exhausted patients than in the nonexhausted patients (p = .02). hsCRP, IL-1ra, IL-6, and neopter in concentrations did not change over this time period. CONCLUSIONS:The data are suggestive of a negative association of MIF with CAD and of MIF with exhaustion. The observation that those patients who remained exhausted had lower concentrations of MIF fits into earlier observations that suggested that exhausted coronary patients may be characterized by a hypoactivity of the hypothalamic-pituitary-adrenocortical axis.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Kwaijtaal M,van der Ven AJ,van Diest R,Bruggeman CA,Bär FW,Calandra T,Appels A,Sweep FCdoi
10.1097/PSY.0b013e31802b8750subject
Has Abstractpub_date
2007-01-01 00:00:00pages
68-73issue
1eissn
0033-3174issn
1534-7796pii
69/1/68journal_volume
69pub_type
杂志文章,多中心研究,随机对照试验abstract::Factor analysis of responses from 1002 men and women were used to define two subscales of the Cook and Medley Hostility Scale. Both the Cynicism and the Paranoid Alienation subscale described attitudes of mistrust and alienation, and both were correlated with MMPI factors measuring aspects of psychopathology. It was s...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198603000-00014
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abstract::The association of apolipoprotein E (apoE) polymorphism with temperament and Type A behavior was studied in 1577 randomly selected healthy children, adolescents, and young adults during a follow-up period of 9 years. Temperament was correlated with apoE phenotypes. Motor activity, even hyperactivity, in childhood and ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/00006842-199303000-00004
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abstract:OBJECTIVE:Attitudes have a potential role to play in the experience of menopause. The objective of this study was to examine the degree to which attitudes toward menopause and aging vary across ethnic groups and menopausal status (ie, premenopausal through postmenopausal). METHODS:More than 16,000 women were interview...
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pub_type: 杂志文章
doi:10.1097/00006842-199911000-00023
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abstract:OBJECTIVES:To elucidate the potential relationship between classification of emotional faces and impaired central processing in eating disorders and to investigate the potential mediatory role of alexithymia and depression in this relationship. METHODS:Visual-evoked potentials (VEPs) to emotional faces and classificat...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31817e41e6
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abstract:OBJECTIVE:To examine the association between dietary folate, riboflavin, vitamin B-6, and vitamin B-12 and depressive symptoms in a group of adolescents. METHODS:This cross-sectional study, conducted in all public junior high schools in Naha City and Nago City, Okinawa, Japan, included 3,067 boys and 3,450 girls aged ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181f02f15
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abstract:OBJECTIVE:To investigate the risks of acute organ dysfunction and death in intensive care unit (ICU) patients with schizophrenia. METHODS:Using a retrospective matched cohort design, we compared 203 schizophrenic patients to 2036 demographically matched (1:10) nonschizophrenic patients with first-time ICU admission be...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182280016
更新日期:2011-09-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199805000-00004
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abstract:OBJECTIVE:An attachment model was used to understand how maternal sensitivity and adverse childhood experiences are related to somatization. METHODS:We examined maternal sensitivity at 6 and 18 months and somatization at 5 years in 292 children in a longitudinal cohort study. We next examined attachment insecurity and...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000437
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199411000-00010
更新日期:1994-11-01 00:00:00
abstract::The Rosenberg Self-Esteem Scale, Beck Depression Inventory, and Sullivan Diabetic Adjustment Scale were administered to 105 adolescent girls with diabetes. Results indicate that levels of self-esteem and depression highly correlate with the level of adjustment as assessed on the Diabetic Adjustment Scale (DAS). That i...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197903000-00006
更新日期:1979-03-01 00:00:00
abstract:OBJECTIVE:To assess whether a life-style physical activity intervention improved antibody response to a pneumococcal vaccination in sedentary middle-aged women. METHODS:Eighty-nine sedentary women completed a 16-week exercise (physical activity consultation, pedometer, telephone/e-mail prompts; n = 44) or control (adv...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/PSY.0b013e3182a0b664
更新日期:2013-10-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000138116.12495.a2
更新日期:2004-09-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000188576.54698.36
更新日期:2005-11-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197806000-00004
更新日期:1978-06-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000221229.43272.9d
更新日期:2006-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/PSY.0000000000000603
更新日期:2018-07-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197908000-00004
更新日期:1979-08-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2004-07-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198605000-00006
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doi:10.1097/PSY.0b013e3181f60fcc
更新日期:2010-11-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182572599
更新日期:2012-05-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197910000-00003
更新日期:1979-10-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31814d4e6a
更新日期:2007-09-01 00:00:00
abstract::This paper examines the relation of two personality characteristics (dominance and anger) to hormones in normally aging men. The relation of the Jackson Personality Research Form E Dominance subscale and the Spielberger Anger Expression scale to serum levels of 17 endocrine variables, including testosterone (T) and di...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199107000-00003
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:To determine why lower social integration predicts higher mortality in patients with coronary heart disease (CHD). METHODS:The association between social integration and mortality was examined prospectively in 1019 outpatients with stable CHD from the Heart and Soul Study. Baseline social integration was ass...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000100
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:Accurate perception of asthma episodes increases the likelihood that they will be managed effectively. The purpose of the study was to examine the effect of feedback in a signal detection task on perception of increased airflow obstruction in children with persistent asthma. METHODS:The effect of feedback tr...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/PSY.0b013e3182a8bcde
更新日期:2013-10-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
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更新日期:1998-09-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/PSY.0b013e3181cbd38b
更新日期:2010-02-01 00:00:00
abstract::A sample consisting of 54 patients and 31 dentists of Chinese, Anglo-American, and Scandinavian ethnic origin were interviewed about their ways of coping with pain. Instruments designed to assess pain coping were constructed from the descriptions elicited by the interviews. The interview data thus served as the basis ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199003000-00005
更新日期:1990-03-01 00:00:00