Exhaustion is associated with low macrophage migration inhibitory factor expression in patients with coronary artery disease.

Abstract:

OBJECTIVE:Macrophage migration inhibitory factor (MIF), a protein secreted by immune cells and the pituitary gland, may be associated with coronary artery disease (CAD) and the mental state of coronary patients. The first origin of MIF suggests positive, the second negative associations. The aim of this study was to explore the direction of the association of MIF with CAD and of MIF with exhaustion, if any. METHODS:Participants were 194 patients who had been recently treated by percutaneous coronary intervention (PCI) and who were exhausted at the start of the study. Half entered a behavioral intervention program. MIF, C-reactive protein, interleukin (IL)-6, IL-1 receptor antagonist, and neopterin were measured in blood collected 6 weeks after PCI (baseline) and 6 and 18 months after baseline. A single measurement of MIF was also available for 129 age- and sex-matched healthy individuals (reference group). RESULTS:At baseline, MIF in patients undergoing PCI was significantly lower than in the reference group (p < .01). New cardiac events occurred twice as often in the lowest quartile than in the highest quartile of MIF concentrations. However, the association was not significant (chi(2) = 2.27; df = 3; p = .52). During follow up, MIF concentrations increased significantly in patients undergoing PCI (p < .001). At 18 months, MIF concentrations were significantly lower in the exhausted patients than in the nonexhausted patients (p = .02). hsCRP, IL-1ra, IL-6, and neopter in concentrations did not change over this time period. CONCLUSIONS:The data are suggestive of a negative association of MIF with CAD and of MIF with exhaustion. The observation that those patients who remained exhausted had lower concentrations of MIF fits into earlier observations that suggested that exhausted coronary patients may be characterized by a hypoactivity of the hypothalamic-pituitary-adrenocortical axis.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Kwaijtaal M,van der Ven AJ,van Diest R,Bruggeman CA,Bär FW,Calandra T,Appels A,Sweep FC

doi

10.1097/PSY.0b013e31802b8750

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

68-73

issue

1

eissn

0033-3174

issn

1534-7796

pii

69/1/68

journal_volume

69

pub_type

杂志文章,多中心研究,随机对照试验
  • Cynicism and paranoid alienation in the Cook and Medley HO Scale.

    abstract::Factor analysis of responses from 1002 men and women were used to define two subscales of the Cook and Medley Hostility Scale. Both the Cynicism and the Paranoid Alienation subscale described attitudes of mistrust and alienation, and both were correlated with MMPI factors measuring aspects of psychopathology. It was s...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198603000-00014

    authors: Costa PT Jr,Zonderman AB,McCrae RR,Williams RB Jr

    更新日期:1986-03-01 00:00:00

  • Dependence between apolipoprotein E phenotypes and temperament in children, adolescents, and young adults.

    abstract::The association of apolipoprotein E (apoE) polymorphism with temperament and Type A behavior was studied in 1577 randomly selected healthy children, adolescents, and young adults during a follow-up period of 9 years. Temperament was correlated with apoE phenotypes. Motor activity, even hyperactivity, in childhood and ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00006842-199303000-00004

    authors: Keltikangas-Järvinen L,Räikkönen K,Lehtimäki T

    更新日期:1993-03-01 00:00:00

  • Attitudes toward menopause and aging across ethnic/racial groups.

    abstract:OBJECTIVE:Attitudes have a potential role to play in the experience of menopause. The objective of this study was to examine the degree to which attitudes toward menopause and aging vary across ethnic groups and menopausal status (ie, premenopausal through postmenopausal). METHODS:More than 16,000 women were interview...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199911000-00023

    authors: Sommer B,Avis N,Meyer P,Ory M,Madden T,Kagawa-Singer M,Mouton C,Rasor NO,Adler S

    更新日期:1999-11-01 00:00:00

  • Impaired central processing of emotional faces in anorexia nervosa.

    abstract:OBJECTIVES:To elucidate the potential relationship between classification of emotional faces and impaired central processing in eating disorders and to investigate the potential mediatory role of alexithymia and depression in this relationship. METHODS:Visual-evoked potentials (VEPs) to emotional faces and classificat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31817e41e6

    authors: Pollatos O,Herbert BM,Schandry R,Gramann K

    更新日期:2008-07-01 00:00:00

  • Dietary folate, riboflavin, vitamin B-6, and vitamin B-12 and depressive symptoms in early adolescence: the Ryukyus Child Health Study.

    abstract:OBJECTIVE:To examine the association between dietary folate, riboflavin, vitamin B-6, and vitamin B-12 and depressive symptoms in a group of adolescents. METHODS:This cross-sectional study, conducted in all public junior high schools in Naha City and Nago City, Okinawa, Japan, included 3,067 boys and 3,450 girls aged ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181f02f15

    authors: Murakami K,Miyake Y,Sasaki S,Tanaka K,Arakawa M

    更新日期:2010-10-01 00:00:00

  • Increased risks of acute organ dysfunction and mortality in intensive care unit patients with schizophrenia: a nationwide population-based study.

    abstract:OBJECTIVE:To investigate the risks of acute organ dysfunction and death in intensive care unit (ICU) patients with schizophrenia. METHODS:Using a retrospective matched cohort design, we compared 203 schizophrenic patients to 2036 demographically matched (1:10) nonschizophrenic patients with first-time ICU admission be...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182280016

    authors: Shen HN,Lu CL,Yang HH

    更新日期:2011-09-01 00:00:00

  • Psychosocial work characteristics and social support as predictors of SF-36 health functioning: the Whitehall II study.

    abstract:OBJECTIVE:To assess whether work characteristics and social support are predictors of physical, psychological, and social functioning. METHOD:Work characteristics (Karasek and Siegrist models) and social support at baseline were used to predict health functioning measured by the SF-36 General Health Survey 5 years lat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199805000-00004

    authors: Stansfeld SA,Bosma H,Hemingway H,Marmot MG

    更新日期:1998-05-01 00:00:00

  • An Attachment-Based Model of the Relationship Between Childhood Adversity and Somatization in Children and Adults.

    abstract:OBJECTIVE:An attachment model was used to understand how maternal sensitivity and adverse childhood experiences are related to somatization. METHODS:We examined maternal sensitivity at 6 and 18 months and somatization at 5 years in 292 children in a longitudinal cohort study. We next examined attachment insecurity and...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000437

    authors: Maunder RG,Hunter JJ,Atkinson L,Steiner M,Wazana A,Fleming AS,Moss E,Gaudreau H,Meaney MJ,Levitan RD

    更新日期:2017-06-01 00:00:00

  • Modeling and reinforcement of the sick role during childhood predicts adult illness behavior.

    abstract::Previous studies suggest that the ways in which parents respond to children's health complaints (reinforcement) and the ways in which they cope with their own illnesses (modeling) influence the frequency of symptoms, disability days, and health care visits made by these children when they grow up. However, previous st...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199411000-00010

    authors: Whitehead WE,Crowell MD,Heller BR,Robinson JC,Schuster MM,Horn S

    更新日期:1994-11-01 00:00:00

  • Adjustment in diabetic adolescent girls: II. Adjustment, self-esteem, and depression in diabetic adolescent girls.

    abstract::The Rosenberg Self-Esteem Scale, Beck Depression Inventory, and Sullivan Diabetic Adjustment Scale were administered to 105 adolescent girls with diabetes. Results indicate that levels of self-esteem and depression highly correlate with the level of adjustment as assessed on the Diabetic Adjustment Scale (DAS). That i...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197903000-00006

    authors: Sullivan BJ

    更新日期:1979-03-01 00:00:00

  • A life-style physical activity intervention and the antibody response to pneumococcal vaccination in women.

    abstract:OBJECTIVE:To assess whether a life-style physical activity intervention improved antibody response to a pneumococcal vaccination in sedentary middle-aged women. METHODS:Eighty-nine sedentary women completed a 16-week exercise (physical activity consultation, pedometer, telephone/e-mail prompts; n = 44) or control (adv...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PSY.0b013e3182a0b664

    authors: Long JE,Ring C,Bosch JA,Eves F,Drayson MT,Calver R,Say V,Allen D,Burns VE

    更新日期:2013-10-01 00:00:00

  • Regional prevalence of fatiguing illnesses in the United States before and after the terrorist attacks of September 11, 2001.

    abstract:OBJECTIVE:Stress or emotional traumas are considered risk factors for unexplained fatiguing illnesses. From July to December 2001, the Centers for Disease Control and Prevention conducted a multigeographical pilot study to test the feasibility of a survey to estimate the prevalence of fatiguing illnesses in the United ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000138116.12495.a2

    authors: Heim C,Bierl C,Nisenbaum R,Wagner D,Reeves WC

    更新日期:2004-09-01 00:00:00

  • Socioeconomic position, cognitive function, and clustering of cardiovascular risk factors in adolescence: findings from the Mater University Study of Pregnancy and its outcomes.

    abstract:OBJECTIVES:The objectives of this study were to examine the extent of clustering of smoking, high levels of television watching, overweight, and high blood pressure among adolescents and whether this clustering varies by socioeconomic position and cognitive function. METHODS:This study was a cross-sectional analysis o...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000188576.54698.36

    authors: Lawlor DA,O'Callaghan MJ,Mamun AA,Williams GM,Bor W,Najman JM

    更新日期:2005-11-01 00:00:00

  • Patterning of cognitive and somatic processes in the self-regulation of anxiety: effects of meditation versus exercise.

    abstract::Davidson and Schwartz (1) have proposed a psychobiological analysis of anxiety that emphasizes the patterning of multiple processes in the generation and self-regulation of this state. The present article specifically reviews recent research on cognitive and somatic components of anxiety. A dual component scale which ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197806000-00004

    authors: Schwartz GE,Davidson RJ,Goleman DJ

    更新日期:1978-06-01 00:00:00

  • Altered blood coagulation in patients with posttraumatic stress disorder.

    abstract:OBJECTIVE:Posttraumatic stress disorder (PTSD) has been associated with an increased cardiovascular risk, though the pathophysiologic mechanisms involved are elusive. A hypercoagulable state before occurrence of coronary thrombosis contributes to atherosclerosis development. We investigated whether PTSD would be associ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000221229.43272.9d

    authors: von Känel R,Hepp U,Buddeberg C,Keel M,Mica L,Aschbacher K,Schnyder U

    更新日期:2006-07-01 00:00:00

  • Vagal Mediation of Low-Frequency Heart Rate Variability During Slow Yogic Breathing.

    abstract:OBJECTIVE:Changes in heart rate variability (HRV) associated with breathing (respiratory sinus arrhythmia) are known to be parasympathetically (vagally) mediated when the breathing rate is within the typical frequency range (9-24 breaths per minute [bpm]; high-frequency HRV). Slow yogic breathing occurs at rates below ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000603

    authors: Kromenacker BW,Sanova AA,Marcus FI,Allen JJB,Lane RD

    更新日期:2018-07-01 00:00:00

  • Predictability, attentional focus, sex role orientation, and menstrual-related stress.

    abstract::Two separate studies assessed the influence on menstrual distress and related inhibition of such variables as predictability of onset, dispositional susceptibility to cultural expectations, and the attentional focus provided by labels. Greater predictability of onset was associated with more positive feedlings about m...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197908000-00004

    authors: Chernovetz ME,Jones WH,Hansson RO

    更新日期:1979-08-01 00:00:00

  • Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm).

    abstract:OBJECTIVE:Melissa officinalis (lemon balm) is contemporaneously used as a mild sedative and/or calming agent. Although recent research has demonstrated modulation of mood in keeping with these roles, no studies to date have directly investigated the effects of this herbal medication on laboratory-induced psychological ...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.psy.0000132877.72833.71

    authors: Kennedy DO,Little W,Scholey AB

    更新日期:2004-07-01 00:00:00

  • Life stresses and premature labor: real connection or artifactual findings?

    abstract::Three studies on the relationship between life stresses and premature labor were conducted. The first was a retrospective comparison of life events between a group of women who had had premature labor and a group of controls. It was carried out between 3 and 6 months after the premature delivery to neutralize possible...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198605000-00006

    authors: Omer H,Friedlander D,Palti Z,Shekel I

    更新日期:1986-05-01 00:00:00

  • Momentary work worries, marital disclosure, and salivary cortisol among parents of young children.

    abstract:OBJECTIVE:To investigate whether worries about work are linked to people's own cortisol levels and their spouses' cortisol levels in everyday life and whether marital factors may moderate these links. Although research has shown that satisfying marriages can buffer the physiological effects of everyday stress, the spec...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181f60fcc

    authors: Slatcher RB,Robles TF,Repetti RL,Fellows MD

    更新日期:2010-11-01 00:00:00

  • A randomized, wait-list controlled clinical trial: the effect of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients.

    abstract:OBJECTIVE:The objective of this study was to assess the effects of participation in a mindfulness meditation-based stress reduction program on mood disturbance and symptoms of stress in cancer outpatients. METHODS:A randomized, wait-list controlled design was used. A convenience sample of eligible cancer patients enro...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-200009000-00004

    authors: Speca M,Carlson LE,Goodey E,Angen M

    更新日期:2000-09-01 00:00:00

  • Daily psychological demands are associated with 6-year progression of carotid artery atherosclerosis: the Pittsburgh Healthy Heart Project.

    abstract:OBJECTIVE:We examine associations between the perception of ongoing psychological demands by ecological momentary assessment (EMA) and 6-year changes in carotid artery atherosclerosis by ultrasonography. METHODS:A total of 270 initially healthy participants collected ambulatory blood pressure (ABP) and recorded their ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182572599

    authors: Kamarck TW,Shiffman S,Sutton-Tyrrell K,Muldoon MF,Tepper P

    更新日期:2012-05-01 00:00:00

  • Psychological correlates of progression of atherosclerosis in men.

    abstract::Patients who underwent repetitive repetitive coronary angiograms at an average interval of 17 months completed the Jenkins Activity Survey (n = 66) and were given the Rosenman diagnostic interview to measure Type A behavior (n = 45). Significant progression of coronary artery disease was judged to be an increase in oc...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197910000-00003

    authors: Krantz DS,Sanmarco MI,Selvester RH,Matthews KA

    更新日期:1979-10-01 00:00:00

  • Is cancer risk associated with anger control and negative affect? Findings from a prospective cohort study.

    abstract:OBJECTIVE:To examine the associations between anger control and negative affect and the risk of five common cancers and total cancers. Possible associations between emotional states and the risk of cancer have long been postulated. METHODS:Prospective cohort study with average follow-up of 9 years. A total of 19,730 a...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31814d4e6a

    authors: White VM,English DR,Coates H,Lagerlund M,Borland R,Giles GG

    更新日期:2007-09-01 00:00:00

  • The relation between dominance, anger, and hormones in normally aging men: results from the Massachusetts Male Aging Study.

    abstract::This paper examines the relation of two personality characteristics (dominance and anger) to hormones in normally aging men. The relation of the Jackson Personality Research Form E Dominance subscale and the Spielberger Anger Expression scale to serum levels of 17 endocrine variables, including testosterone (T) and di...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199107000-00003

    authors: Gray A,Jackson DN,McKinlay JB

    更新日期:1991-07-01 00:00:00

  • Social integration and mortality in patients with coronary heart disease: findings from the Heart and Soul Study.

    abstract:OBJECTIVE:To determine why lower social integration predicts higher mortality in patients with coronary heart disease (CHD). METHODS:The association between social integration and mortality was examined prospectively in 1019 outpatients with stable CHD from the Heart and Soul Study. Baseline social integration was ass...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000100

    authors: Kreibig SD,Whooley MA,Gross JJ

    更新日期:2014-10-01 00:00:00

  • Effects of feedback on the perception of inspiratory resistance in children with persistent asthma: a signal detection approach.

    abstract:OBJECTIVE:Accurate perception of asthma episodes increases the likelihood that they will be managed effectively. The purpose of the study was to examine the effect of feedback in a signal detection task on perception of increased airflow obstruction in children with persistent asthma. METHODS:The effect of feedback tr...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PSY.0b013e3182a8bcde

    authors: Harver A,Kotses H,Ersek J,Humphries CT,Ashe WS Jr,Black HR 2nd

    更新日期:2013-10-01 00:00:00

  • Are hostility and anxiety associated with carotid atherosclerosis in healthy postmenopausal women?

    abstract:OBJECTIVE:In this article, we evaluated the prospective association between measures of trait anger, hostility, and anxiety and indices of carotid atherosclerosis in 200 healthy middle-aged postmenopausal women. METHODS:Starting in 1983, 541 premenopausal women were evaluated for their levels of standard cardiovascula...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199809000-00021

    authors: Matthews KA,Owens JF,Kuller LH,Sutton-Tyrrell K,Jansen-McWilliams L

    更新日期:1998-09-01 00:00:00

  • Conditioned pharmacotherapeutic effects: a preliminary study.

    abstract:OBJECTIVE:To test the hypothesize that psoriasis patients treated under a partial schedule of pharmacologic (corticosteroid) reinforcement would show less severe symptoms and relapse than those given the same amount of drug under standard conditions. Behavioral conditioning as an inherent component of many pharmacother...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/PSY.0b013e3181cbd38b

    authors: Ader R,Mercurio MG,Walton J,James D,Davis M,Ojha V,Kimball AB,Fiorentino D

    更新日期:2010-02-01 00:00:00

  • Ethnographic assessment of pain coping perceptions.

    abstract::A sample consisting of 54 patients and 31 dentists of Chinese, Anglo-American, and Scandinavian ethnic origin were interviewed about their ways of coping with pain. Instruments designed to assess pain coping were constructed from the descriptions elicited by the interviews. The interview data thus served as the basis ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199003000-00005

    authors: Moore R

    更新日期:1990-03-01 00:00:00