Changing the paradigm of organ utilization from PHS increased-risk donors: an opportunity whose time has come?

abstract：:The aging of the on-dialysis population raises the issue of whether to propose elderly patients for kidney transplantation and how to manage their immunosuppression. This study aimed to analyze the outcome of kidney transplantation on an Italian series of elderly recipients. We included in this retrospective study all...

journal_title：Clinical transplantation

authors： Neri F,Furian L,Cavallin F,Ravaioli M,Silvestre C,Donato P,La Manna G,Pinna AD,Rigotti P

更新日期：2017-10-01 00:00:00

abstract：:Based on native CT scans of the pelvic region using a standardized calcification score, evaluation of iliac vascular calcification was performed between 2008 and 2012 prior to listing for renal transplantation in 205 patients with chronic kidney disease. Vascular calcification showed a decrease from proximal to distal...

journal_title：Clinical transplantation

authors： Kahn J,Ram LM,Eberhard K,Groselj-Strele A,Obermayer-Pietsch B,Müller H

更新日期：2017-03-01 00:00:00

abstract：:Splenic artery "steal" syndrome after orthotopic liver transplantation (OLT) is an important cause of graft dysfunction. Direct pressure measurement in the hepatic (HA) and radial artery (RA) may identify patients at risk allowing its prevention. This observational study compared radial and hepatic mean arterial press...

journal_title：Clinical transplantation

authors： Wojcicki M,Pakosz-Golanowska M,Lubikowski J,Post M,Jarosz K,Milkiewicz P

更新日期：2012-03-01 00:00:00

abstract：:Xenotransplantation is a potential strategy to overcome the shortage of human donor organs. As this technique has a major medical and psychological impact on patients and their family and friends, the attitude of patients currently waiting for organ transplantation is important. Therefore, we conducted a survey on the...

journal_title：Clinical transplantation

authors： Stadlbauer V,Stiegler P,Müller S,Schweiger M,Sereingg M,Tscheliessnigg KH,Freidl W

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Arterial stiffness and left ventricular hypertrophy (LVH) are major independent risk factors for cardiovascular disease in healthy and renal population. In this study, we aimed to investigate comparative long-term effects of renal transplantation (RTx) and of hemodialysis (HD) on both arterial stiffness and ...

journal_title：Clinical transplantation

authors： Keven K,Calayoglu R,Sengul S,Dincer I,Kutlay S,Erturk S,Erbay B,Nergizoglu G

更新日期：2008-05-01 00:00:00

abstract：:Skin cancer is a common, potentially life-threatening malignancy in organ transplant recipients (OTR), and it is important for transplant physicians to be aware of patient history of skin cancer. Patient self-report represents a quick method of obtaining past medical history of skin cancer but no study has validated t...

journal_title：Clinical transplantation

authors： Dybbro E,Mihalis E,Hirose R,Arron ST

更新日期：2012-03-01 00:00:00

abstract：:The potential influence of racially or ethnically diverse cultural perspectives on patient compliance with post-transplant treatments is discussed. Domains of competency regarding culturally sensitive clinical practice are outlined to assist providers in better understanding the perspectives that may influence the vie...

journal_title：Clinical transplantation

authors： Prieto LR,Miller DS,Gayowski T,Marino IR

更新日期：1997-12-01 00:00:00

abstract：:Based on the results achieved in single human hand transplantations, we decided to perform the first double hand transplantation with a conventional immunosuppressive protocol in a patient with a high potential for functional recovery. Two years after transplantation the efficacy and the safety of this immunosuppressi...

journal_title：Clinical transplantation

authors： Petruzzo P,Revillard JP,Kanitakis J,Lanzetta M,Hakim NS,Lefrançois N,Owen E,Dubernard JM

更新日期：2003-10-01 00:00:00

abstract：INTRODUCTION:A long-term prospective randomized trial evaluating alemtuzumab, a humanized anti-CD52 monoclonal antibody, in a predominantly non-Caucasian population has yet to be reported. METHODS:Ninety deceased donor (DD) first renal transplant recipients were randomized into three different antibody induction group...

journal_title：Clinical transplantation

authors： Ciancio G,Burke GW,Gaynor JJ,Roth D,Kupin W,Rosen A,Cordovilla T,Tueros L,Herrada E,Miller J

更新日期：2008-03-01 00:00:00

abstract：:Using lacerated livers for liver transplantation (LTx) can add an option to the extended donor criteria. We present an LTx case using a severely lacerated liver and review of the literature for reported cases. We used a high-grade lacerated liver from a 19-yr-old brain-dead patient caused by traffic accident. The live...

journal_title：Clinical transplantation

authors： Mehrabi A,Fonouni H,Ahmadi R,Schmied BM,Müller SA,Welsch T,Hallscheidt P,Zeier M,Weitz J,Schmidt J

更新日期：2009-06-01 00:00:00

abstract：INTRODUCTION:Atherosclerosis is a serious complication and leading cause of mortality in renal transplant recipients (RTRs). Hyperlipidemia may be associated with progression of renal disease and chronic allograft dysfunction. Similarities in the pathogenesis of glomerulosclerosis and atherosclerosis have been proposed...

journal_title：Clinical transplantation

authors： Kahraman S,Kiykim AA,Altun B,Gençtoy G,Arici M,Gulsun M,Erdem Y,Yasavul U,Turgan C,Cağlar S

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The purpose of this work was to investigate the association of vertebral and peripheral fractures 10 yr after grafting with bone metabolic markers and body mass density (BMD). PATIENTS AND METHODS:One hundred thirty-eight recipients with stable graft function were included in a cross-sectional study. Graft ...

journal_title：Clinical transplantation

authors： Jiménez S,Marcén R,Vaamonde C,Caballero C,Fernández-Rodríguez A,Villafruela JJ,Galeano C,Teruel JL,Quereda C

更新日期：2016-02-01 00:00:00

abstract：:The exact mechanism of acute and chronic allograft rejection still remains unclear. The chemokine SDF-1 as mediator of allograft rejection has been under intensive investigation in liver, cardiac and bone marrow transplantation, whereas in renal transplantation, there are no reports about SDF-1 to date. This study was...

journal_title：Clinical transplantation

authors： Hoffmann U,Banas B,Krüger B,Banas M,Bergler T,Böger C,Kammerl M,Obed A,Rümmele P,Segerer S,Riegger GA,Krämer BK

更新日期：2006-11-01 00:00:00

abstract：:This study investigated the association between religious beliefs and opinions on xenotransplantation among students from three different countries. A lower proportion of religious students accepted xenotransplantation than did non-religious students. A higher proportion of Protestant students seemed to accept xenotra...

journal_title：Clinical transplantation

authors： Hagelin J,Hau J,Schapiro SJ,Suleman MA,Carlsson HE

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Short-term survival after kidney transplantation is excellent, but long-term survival remains low and is equivalent to non-end-stage renal disease patients with many invasive malignancies. The aim of the study was to explore vitamin D status in the early phase after transplantation as a prognostic marker for...

journal_title：Clinical transplantation

authors： Thorsen IS,Bleskestad IH,Åsberg A,Hartmann A,Skadberg Ø,Brede C,Ueland T,Pasch A,Reisaeter AV,Gøransson LG

更新日期：2019-05-01 00:00:00

abstract：:Obesity and weight gain are serious concerns after solid organ transplantation (Tx); however, no unbiased comparison regarding body weight parameter evolution across organ groups has yet been performed. Using data from the prospective nationwide Swiss Transplant Cohort Study, we compared the evolution of weight parame...

journal_title：Clinical transplantation

authors： Beckmann S,Nikolic N,Denhaerynck K,Binet I,Koller M,Boely E,De Geest S,Psychosocial Interest Group, Swiss Transplant Cohort Study.

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND/AIMS:There remains a critical shortage of cadaveric organs. At a large inner city level one trauma centre, several strategies were devised and combined to (a). optimize the physiologic status of potential donors, (b). promote awareness of the donation process among health care professionals and (c). perform ...

journal_title：Clinical transplantation

authors： Roth BJ,Sher L,Murray JA,Belzberg H,Mateo R,Heeran A,Romero J,Mone T,Chan L,Selby R

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIM:The aim of this study was to determine whether the expression of CD25, CD28 and CD38 (which reflects the degree of T-cell activation) by peripheral blood mononuclear cells constitutes a useful means of measuring the immune status of liver transplant recipients. METHODS:Fifty-two patients enrolled in a p...

journal_title：Clinical transplantation

authors： Boleslawski E,BenOthman S,Grabar S,Correia L,Podevin P,Chouzenoux S,Soubrane O,Calmus Y,Conti F

更新日期：2008-07-01 00:00:00

abstract：:Immunosuppression leaves transplanted patients at particular risk for severe acute respiratory syndrome 2 (SARS-CoV-2) infection. The specific features of coronavirus disease 2019 (COVID-19) in immunosuppressed patients are largely unknown and therapeutic experience is lacking. Seven transplanted patients (two liver, ...

journal_title：Clinical transplantation

authors： Bösch F,Börner N,Kemmner S,Lampert C,Jacob S,Koliogiannis D,Stangl M,Michel S,Kneidinger N,Schneider C,Fischereder M,Irlbeck M,Denk G,Werner J,Angele MK,Guba MO

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Previous studies indicate that obesity is a risk factor in renal transplantation. However, these analyses did not control for variable donor factors that may strongly influence outcome. To control for donor variables such as age, cause of death, procurement techniques, preservation methods, cold ischaemia ti...

journal_title：Clinical transplantation

authors： Yamamoto S,Hanley E,Hahn AB,Isenberg A,Singh TP,Cohen D,Conti DJ

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Cardiac allograft vasculopathy (CAV) limits survival after heart transplantation (HTx). Between immunologic and non-immunologic factors, reactive oxygen species generation has been proposed as pathogenetic mechanism. This study was aimed at evaluating redox status in HTx recipients and verifying whether it c...

journal_title：Clinical transplantation

authors： De Chiara B,Bigi R,Campolo J,Parolini M,Turazza F,Masciocco G,Frigerio M,Fiorentini C,Parodi O

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVES:Autologous islet transplantation (IAT) following pancreatectomy is now a recognized, albeit highly specialized procedure carried out in a small number of centers worldwide. Current clinical principles and best practice with emphasis on examining the technical aspects of surgery in centers with significant IA...

journal_title：Clinical transplantation

authors： Kumar R,Chung WY,Dennison AR,Garcea G

更新日期：2016-04-01 00:00:00

abstract：:Transplant eligibility for tobacco and/or marijuana using candidates varies among transplant centers. This study compared the impact of marijuana use and tobacco use on kidney transplant recipient outcomes. Kidney transplant recipients at a single center from 2001 to 2015 were reviewed for outcomes of all-cause graft ...

journal_title：Clinical transplantation

authors： Fabbri KR,Anderson-Haag TL,Spenningsby AM,Israni A,Nygaard RM,Stahler PA

更新日期：2019-10-01 00:00:00

abstract：:These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation will review the current state of the art of donor-derived infections. Specifically, the guideline will summarize standardized definitions and approaches to defining imputability, updated data on the e...

journal_title：Clinical transplantation

authors： Wolfe CR,Ison MG,AST Infectious Diseases Community of Practice.

更新日期：2019-09-01 00:00:00

abstract：INTRODUCTION:Previously, increasing age has been a part of the exclusion criteria used when determining eligibility for a pancreas transplant. However, the analysis of pancreas transplantation outcomes based on age groupings has largely been based on single-center reports. METHODS:A UNOS database review of all adult p...

journal_title：Clinical transplantation

authors： Siskind E,Maloney C,Akerman M,Alex A,Ashburn S,Barlow M,Siskind T,Bhaskaran M,Ali N,Basu A,Molmenti E,Ortiz J

更新日期：2014-09-01 00:00:00

abstract：:Acute renal failure (ARF) is a common and severe complication after liver transplantation (LT). The aim of this study was to ascertain the impact of ARF requiring dialysis in the outcome of LT and to analyze the risk factors leading to this event in the early post-operative period. From October 1988 to December 1994, ...

journal_title：Clinical transplantation

authors： Bilbao I,Charco R,Balsells J,Lazaro JL,Hidalgo E,Llopart L,Murio E,Margarit C

更新日期：1998-04-01 00:00:00

abstract：:Enteric drainage of secretions by anastomosing the donor duodenum to the recipient's small bowel has become common in pancreatic transplantation. While it eliminates many problems, endoscopic access to the transplanted duodenum and pancreas is made difficult. After a pancreas kidney transplant, the patient presented w...

journal_title：Clinical transplantation

authors： Green BT,Tuttle-Newhall J,Suhocki P,Smith SR,O'Connor JB

更新日期：2004-02-01 00:00:00

abstract：:Tacrolimus (TAC) is a useful immunosuppressive agent in the prevention of rejection. However, the blood level between its therapeutic and toxic levels is narrow such that its nephrotoxicity is a problem. Moreover, its bioavailability and pharmacokinetics are highly variable. We experienced a case of acute nephrotoxici...

journal_title：Clinical transplantation

authors： Watanabe S,Yamaguchi Y,Hattori M,Chikamoto H,Matsumoto N,Suzuki T,Oonishi M,Horita S,Tokumoto T,Tanabe K,Shiraga H,Toma H,Ito K

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Pharmacologic stress testing is utilized in preference to exercise stress echocardiography (ESE) for cardiac risk evaluation in potential renal transplant recipients due to the perceived lower feasibility of ESE for achieving adequate workload and target heart rate (THR) in this population. METHODS:Consecut...

journal_title：Clinical transplantation

authors： Nerlekar N,Mulley W,Rehmani H,Ramkumar S,Cheng K,Vasanthakumar SA,Rashid H,Barton T,Nasis A,Meredith IT,Moir S,Mottram PM

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Chronic renal failure (CRF) is a common complication of calcineurin inhibitor (CNI)-based immunosuppression following cardiac transplantation (HTx). The aim of this prospective study was to evaluate the impact of an immunosuppressive conversion from CNIs to mycophenolate mofetil (MMF) and steroids in cardiac...

journal_title：Clinical transplantation

authors： Groetzner J,Kaczmarek I,Schirmer J,Uberfuhr P,Gulbins H,Daebritz S,Meiser B,Reichart B

更新日期：2008-09-01 00:00:00