Abstract：
:Splenic artery "steal" syndrome after orthotopic liver transplantation (OLT) is an important cause of graft dysfunction. Direct pressure measurement in the hepatic (HA) and radial artery (RA) may identify patients at risk allowing its prevention. This observational study compared radial and hepatic mean arterial pressures (MAP) measured during 100 OLTs performed in 99 recipients, in whom the HA was considered suitable for the anastomosis. A difference of ≥5 mmHg between the radial and hepatic MAP was arbitrarily chosen as the criterion for inflow modulation. Seven patients fulfilled this criterion showing a MAP gradient that was significantly different compared to the others (-10.8±3.3 vs. 2.6±5.0; p<0.0001). They underwent splenic artery ligation (n=5), arcuate ligament division (n=1) and aortohepatic bypass grafting (n=1) that all resulted in immediate normalization of the arterial inflow pressure to the graft. The splenic artery "steal" syndrome occurred in one patient (day 2 after OLT) in whom the mean HA pressure normalized during OLT following arcuate ligament division, suggesting pathology within the graft as the most likely etiology. Our results indicate that radial MAP can reflect the hepatic MAP during OLT. If a substantial pressure gradient is found, it can be corrected by intraoperative splenic artery ligation or arcuate ligament division.
journal_name
Clin Transplantjournal_title
Clinical transplantationauthors
Wojcicki M,Pakosz-Golanowska M,Lubikowski J,Post M,Jarosz K,Milkiewicz Pdoi
10.1111/j.1399-0012.2011.01478.xsubject
Has Abstractpub_date
2012-03-01 00:00:00pages
223-8issue
2eissn
0902-0063issn
1399-0012journal_volume
26pub_type
杂志文章abstract：:Tacrolimus (TAC) is a calcineurin inhibitor that is used for cardiac allograft rejection. Efficacy and safety data of a combined TAC/mycophenolate mofetil (MMF) therapy in comparison with a TAC/cortisone therapy in heart recipients are lacking. We analysed the clinical outcome of 41 patients who received TAC in combin...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2006.00504.x
更新日期：2006-07-01 00:00:00
abstract：:The purpose of this study was to compare CsA dose monitoring with trough levels (T0) vs. levels obtained 6 h after the morning dose of CsA (T6), with respect to the incidence of acute rejection and renal dysfunction, and the cumulative dose, as well as the cost of CsA after heart transplantation. Twenty consecutive ad...
journal_title：Clinical transplantation
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:Urinary tract infections (UTIs) account for significant morbidity after kidney transplantation (KT). Screening for asymptomatic bacteruria (AB) has proven to be beneficial in certain population including pregnant women; however, it is not well-studied in KT population. We reviewed the incidence, clinical feat...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.12954
更新日期：2017-05-01 00:00:00
abstract：:Reducing acute care utilization is a means of improving long-term patient outcomes. We sought to assess high inpatient (IP) admission and standalone emergency department (ED) utilization within a 9-month period post-kidney transplantation and to identify mutable factors to reduce utilization. In this ten-year retrospe...
journal_title：Clinical transplantation
pub_type： 临床试验,杂志文章
doi：10.1111/ctr.13522
更新日期：2019-05-01 00:00:00
abstract：:Optimization of maintenance immunosuppression (mIS) regimens in the transplant recipient requires a balance between sufficient potency to prevent rejection and avoidance of excessive immunosuppression to prevent toxicities and complications. The optimal regimen after simultaneous liver-kidney (SLK) transplantation rem...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.14036
更新日期：2020-10-01 00:00:00
abstract：:Mycophenolic acid (MPA) dose reduction is associated with increased risk of rejection and graft loss in renal transplantation. This analysis investigated the impact of MPA dose changes with enteric-coated mycophenolate sodium (EC-MPS) or mycophenolate mofetil (MMF) in de novo heart transplant recipients. In a 12-month...
journal_title：Clinical transplantation
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/j.1399-0012.2008.00887.x
更新日期：2008-11-01 00:00:00
abstract：:The effect of HLA-DR3 gene expression was studied in black cadaveric renal allograft recipients of organs from the same donor race. From January 1984 to June 1992, 70 patients received cadaveric renal allografts at the Medical University of Southern Africa (MEDUNSA). The average age and F:M ratio was 30 years and 1: 1...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:Sarcopenia frequently occurs in cirrhotic patients who are waiting for liver transplantation (LT). This disease is associated with increased morbidity and mortality rates during the LT period. Recently, the careful assessment of nutritional status for end-stage liver disease patients has received a great deal of atten...
journal_title：Clinical transplantation
pub_type： 杂志文章,评审
doi：10.1111/ctr.13741
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:International data on training, work, and lifestyle of transplant physicians and surgeons are scarce. Such data might help in development of uniform education paths and provide insights for young clinicians interested in this field. This study aimed at the evaluation of these data in all transplant-associate...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.12786
更新日期：2016-09-01 00:00:00
abstract：:Aboriginals experience high rates of end-stage renal disease (ESRD) and are less likely to receive a kidney transplant from a living donor. We hypothesized that higher rates of hypertension and diabetes in Aboriginal communities would result in fewer potential living donors coming forward and more exclusions for medic...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2011.01491.x
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:Although innate immunity is crucial to host defense against pathogens, the extent to which innate immune mechanisms participate in the rejection of allogenic tissues in humans is unknown. We hypothesize that activation of innate immunity through Toll-like receptors (TLRs) critically regulates the development...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2005.00436.x
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Vascular thrombosis is the most common cause of early graft loss after transplantation. Routine grayscale and Doppler ultrasound frequently fail to adequately visualize vascular compromise. Contrast-enhanced ultrasound is a novel approach to identifying these complications. METHODS:This was a pro...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.13733
更新日期：2019-12-01 00:00:00
abstract：:Ischemia reperfusion injury (IRI) is an early, non-specific inflammatory response that follows perfusion of warm blood into a cold asanguinous organ following transplantation. The occurrence of IRI may have a pivotal impact on acute and long-term renal allograft function. Initially, IRI contributes to delayed graft fu...
journal_title：Clinical transplantation
pub_type： 杂志文章,评审
doi：10.1111/ctr.12121
更新日期：2013-07-01 00:00:00
abstract：:Anti-Xa monitoring for low molecular weight heparin (LMWH) is currently recommended in obese, renally impaired, and pregnant patients. Substantial evidence indicates that solid organ transplant (SOT) patients are at an increased risk of renal impairment, thus representing a population at risk of LMWH accumulation. The...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.12240
更新日期：2013-11-01 00:00:00
abstract：:Post-transplant lymphoproliferative disorders (PTLDs) are a heterogeneous set of complications of organ transplantation associated with poor patient prognosis. We analyzed the clinicopathological features of PTLDs in 43 adult and pediatric recipients of solid organ or bone marrow transplantation at a large transplant ...
journal_title：Clinical transplantation
pub_type： 临床试验,杂志文章
doi：10.1111/j.1399-0012.2010.01392.x
更新日期：2012-01-01 00:00:00
abstract：:There is limited information regarding the role of flow cytometry crossmatching (FCXM) in primary cadaver kidney allografting and even less about B cell reactivity and graft survival (GS). Furthermore, there is little or no published data concerning reaction strength (cutoff value), the effect of historic sera reactio...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：BACKGROUND:With the growing numbers of liver transplant recipients, it is increasingly important to understand the risks of de novo malignancy after liver transplantation. AIM:To characterize the incidence of de novo malignancy after liver transplantation compared with a control non-transplant population. METHODS:We ...
journal_title：Clinical transplantation
pub_type： 临床试验,杂志文章
doi：10.1111/ctr.12171
更新日期：2013-07-01 00:00:00
abstract：:Cytomegalovirus (CMV) infection complicates the post-operative course of patients receiving solid organ transplants. While ganciclovir has significantly reduced the direct effects of CMV infection, some patients cannot tolerate the optimal therapeutic exposure required for CMV prevention and treatment. Few reports dir...
journal_title：Clinical transplantation
pub_type： 杂志文章,评审
doi：10.1111/j.1399-0012.2008.00942.x
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND:The accurate estimation of liver volume and right/left ratio in donor candidates is critical, but there is no method using portal vein (PV) flow. METHODS:Of 125 donor candidates, right/left liver volume ratio was estimated using ultrasound (US)-PV area ratio and Doppler US-PV flow ratio, and the results wer...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.13050
更新日期：2017-09-01 00:00:00
abstract：:The donation of organs and tissues for the benefit of another person is an altruistic act and one that is a guaranteed option for the next-of-kin through various national Required Request legislations. At the Washington Hospital Center we have developed an approach that permits organ recovery from non-heart beating do...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：BACKGROUND:It is unclear whether sirolimus, a newer immunosuppressive agent, widely used in renal transplantation, affects male sex hormone levels or sexual function. METHODS:Sex hormone profiles in male renal transplant recipients were obtained and compared between a sirolimus-treated group and a group not on sirolim...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2005.00257.x
更新日期：2005-04-01 00:00:00
abstract：:An exploratory, post hoc analysis was performed using data from a prospective, multicenter, open-label, randomized, two-period (14 d per period), two-sequence, crossover, steady-state pharmacokinetic study comparing generic tacrolimus (Sandoz) vs. reference tacrolimus in stable renal transplant patients receiving thei...
journal_title：Clinical transplantation
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/ctr.12256
更新日期：2013-11-01 00:00:00
abstract：:Donor lung allocation in the United States focuses on decreasing waitlist mortality and improving recipient outcomes. The implementation of allocation policy to match deceased donor lungs to waitlisted patients occurs through a unique partnership between government and private organizations, namely the Organ Procureme...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.13873
更新日期：2020-07-01 00:00:00
abstract：:Urinary tract infections (UTIs) are the most common infectious complication following renal transplantation. Previous studies uniformly report that renal transplant recipients develop UTIs more often than the general population, but widely differ on how frequently UTIs occur after transplantation. These studies also d...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2005.00327.x
更新日期：2005-04-01 00:00:00
abstract：:The potential influence of racially or ethnically diverse cultural perspectives on patient compliance with post-transplant treatments is discussed. Domains of competency regarding culturally sensitive clinical practice are outlined to assist providers in better understanding the perspectives that may influence the vie...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：:In Norway living kidney donors account for approximately 40% of all renal transplants. There is a shortage of information about how living kidney donors experience the donation process during the initial recovery from surgery. The aim of this study was to explore physical and psychosocial issues related to the experie...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2004.00304.x
更新日期：2005-02-01 00:00:00
abstract：:In the general population, obesity is associated with an increased risk of developing hypertension (HTN), type 2 diabetes mellitus (DM), and end-stage renal disease (ESRD). Therefore, most transplant centers have a body mass index (BMI) threshold for accepting living kidney donors. But there have been no studies of po...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.13360
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine whether bacterial contamination of islets affects graft success after total pancreatectomy with islet autotransplantation (TPIAT). BACKGROUND:Factors associated with insulin independence after TPIAT are inconclusive. Although bacterial contamination does not preclud...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.12842
更新日期：2016-11-01 00:00:00
abstract：:Adverse symptoms of immunosuppressants (ASI) impact quality of life (QOL) in solid organ transplant recipients; however, standardized approaches for active ASI surveillance and intervention are lacking. While management is highly clinician dependent, clinician views remain largely unexplored. We surveyed Canadian Soci...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.12940
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:A questionnaire study was designed to determine whether the quality of life benefit provided by receiving a kidney-pancreas (KP) transplant increased the incentive to return to work, compared with patients receiving a kidney alone (KA) transplant. METHODS:A confidential questionnaire was sent to 58 patients...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2004.00115.x
更新日期：2004-02-01 00:00:00
