Abstract:
BACKGROUND:A questionnaire study was designed to determine whether the quality of life benefit provided by receiving a kidney-pancreas (KP) transplant increased the incentive to return to work, compared with patients receiving a kidney alone (KA) transplant. METHODS:A confidential questionnaire was sent to 58 patients with insulin-dependent diabetes mellitus who had functioning grafts at least 6 months post-transplant. Thirty-eight patients had received a KP transplant and 20 patients, a KA transplant. RESULTS:Eighty-three percent of patients returned the questionnaire (87% of KP and 75% of KA patients [p: non-significant (ns)]. The pre-transplant demographic variables of age, gender, educational status, and need for dialysis, were equivalent between the KP and KA groups, respectively (p: ns). At the time of transplantation 39% of KP patients and 33% of KA patients were employed at least 20 h/wk (p: ns). However, post-transplant significantly more KP patients (73%) were working compared with KA patients (27%, p: 0.04). Additionally, pre-transplant employment was independently associated with post-transplant work status (p: 0.01). CONCLUSION:These data suggest that the improvement in quality of life associated with pancreas transplantation provide an added incentive for diabetics with renal insufficiency to seek employment.
journal_name
Clin Transplantjournal_title
Clinical transplantationauthors
Knight RJ,Daly Ldoi
10.1111/j.1399-0012.2004.00115.xsubject
Has Abstractpub_date
2004-02-01 00:00:00pages
49-52issue
1eissn
0902-0063issn
1399-0012journal_volume
18pub_type
杂志文章abstract::We examined the UNOS database from 7/15/00-7/17/05 for Regional deceased donor liver utilization. For each region, we performed logistic regression and derived odds ratios (OR) for donor characteristics associated with livers being transplanted outside of the region or not transplanted at all. Regions with smallest an...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-0012.2010.01214.x
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate the efficacy of lamivudine (LAM) monoprophylaxis for patients with non-replicating hepatitis B virus (HBV) infection at orthotopic liver transplantation (OLT). METHODS:Among 128 liver recipients with HBV infection between 1994 and 2004 transplanted at our institution, 6...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-0012.2006.00557.x
更新日期:2007-03-01 00:00:00
abstract::Islet yield is an important predictor of acceptable glucose control after total pancreatectomy with islet autotransplantation (TP-IAT). We assessed if pancreas volume calculated with preoperative MRI could assess islet yield and postoperative outcomes. We reviewed dynamic MRI studies from 154 adult TP-IAT patients (20...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.14008
更新日期:2020-08-01 00:00:00
abstract::The majority of kidney transplant recipients die from cardiovascular events. Physical activity may be a modifiable risk factor for cardiovascular disease following transplant. The goal of our study was to examine adherence to a physical activity intervention following kidney transplant and its impact on metabolic para...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.12553
更新日期:2015-06-01 00:00:00
abstract::Idiopathic interstitial pneumonia (IIP) can occur after stem cell transplantation, but the aetiology is unknown. Based on the association between angiitis syndrome and Helicobacter pylori infection, we identified possible risk factors common to these two conditions. Among 83 patients who underwent stem cell transplant...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1034/j.1399-0012.2003.00053.x
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND AND AIMS:Ischemia-reperfusion injury impacts early liver graft function. Interleukin 6 (IL-6) as early as at reperfusion has shown to predict in-hospital complications, but its impact on vascular complications and long-term outcomes is not ascertained. METHODS:A retrospective study was conducted on all cons...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.13357
更新日期:2018-09-01 00:00:00
abstract::Although many report intra-operative cardiac arrests (ICAs) in liver transplantation (LT), the incidence, major causes, and outcome remain unclear. We aimed to investigate retrospectively, the incidence, nature, and outcome of ICA in Asian population and to identify risk factors for ICA. Consecutive 1071 LTs in an ins...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.12085
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:There have been no published data on use of the the newer immunosuppressants tacrolimus and mycophenolate mofetil (MMF) in high immunological risk renal transplantation. We therefore undertook a prospective study to systematically assess outcomes using these agents as part of an aggressive immunosuppressive ...
journal_title:Clinical transplantation
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1399-0012.2005.00275.x
更新日期:2005-02-01 00:00:00
abstract::Enteric drainage of secretions by anastomosing the donor duodenum to the recipient's small bowel has become common in pancreatic transplantation. While it eliminates many problems, endoscopic access to the transplanted duodenum and pancreas is made difficult. After a pancreas kidney transplant, the patient presented w...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-0012.2004.00111.x
更新日期:2004-02-01 00:00:00
abstract::The infectious disease coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization in March 2020. The impact of COVID-19 on solid organ transplantations, including heart transplantation, is currently unclear. Many transplant programs have been forced to swiftly re-evaluate and adapt th...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.14042
更新日期:2020-09-01 00:00:00
abstract::Flow cytometry crossmatch (FCXM) is a more sensitive technique than classical complement-dependent cytotoxicity (CDC) for the detection of donor-directed antibody before renal transplantation. Nevertheless, the role of FCXM in predicting long-term survival of kidney grafts is still unclear. The purpose of our study wa...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-0012.2004.00226.x
更新日期:2004-10-01 00:00:00
abstract::Endothelial cells (ECs) are involved in allograft rejection and are prime targets, but also key players. HLA antigens are the most prominent targets of alloantibodies in transplantation. Alloantibodies against other antigens such as ABO blood group antigens and non-HLA antigens could also be demonstrated. Alloantibodi...
journal_title:Clinical transplantation
pub_type: 杂志文章,评审
doi:10.1111/j.1399-0012.2012.01675.x
更新日期:2012-07-01 00:00:00
abstract::Research with human transplant recipients has shown that mycophenolate mofetil (MMF) is a powerful and selective immunosuppressant for maintenance therapy following renal transplantation. An additional body of work suggests that it might also be a valuable tool for arresting ongoing rejection episodes. One randomized,...
journal_title:Clinical transplantation
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1996-02-01 00:00:00
abstract::An increasing number of patients and families are utilizing online crowdfunding to support their medical expenses related to organ transplantation. The factors influencing the success of crowdfunding campaigns are poorly understood. Crowdfunding campaigns were abstracted from a popular crowdfunding web site. Campaigns...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.13267
更新日期:2018-06-01 00:00:00
abstract::We report of twins who underwent hematopoietic stem cell transplantation (HSCT) for neonatal acute leukemia. Hospitalized in the same room from the time the first one demonstrated respiratory symptoms, they both developed Pneumocystis jiroveci (formerly carinii) pneumonia (PCP) 2 wk apart. This observation suggests th...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-0012.2005.00346.x
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:In an effort to increase organ donation, the Department of Health and Human Services issued the Final Rule in 1998. The Health Care Financing Administration (HCFA) later required hospitals to notify organ procurement organizations (OPO) of all deaths and imminent deaths in order to remain eligible for Medica...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1034/j.1399-0012.2002.01102.x
更新日期:2002-06-01 00:00:00
abstract::The progression of HCV-related disease is particularly aggressive in the post-transplantation setting. Recipients with recurrent HCV infection undergo repeated liver biopsies in order to estimate disease progression. A strong association was found between serum immunoglobulins levels and hepatic fibrosis in non-transp...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-0012.2007.00657.x
更新日期:2007-05-01 00:00:00
abstract::We prospectively studied efficacy and safety outcomes of two 10-mg doses of intravenous basiliximab on day 0 and day 4 for induction therapy in 17 consecutive de novo heart transplant recipients. By the 2-week assessment post-transplant, there were no deaths, graft failures, or acute cellular rejections (ACRs) ISHLT g...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.13132
更新日期:2017-12-01 00:00:00
abstract::Distinct histopathologic changes occur in acute cellular rejection (ACR), antibody-mediated rejection (AMR), and biopsy-negative rejection (BNR). Cardiovascular magnetic resonance (CMR)-based myocardial tissue characterization can be used to quantify these changes. We assessed T1, T2, and extracellular volume fraction...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.13704
更新日期:2019-10-01 00:00:00
abstract::Obesity has reached epidemic proportions in the USA. Consequently, there are an increasing number of potential organ donors that are obese, but would otherwise be appropriate donors for pancreas transplantation (PTx). This is a retrospective study of all PTx performed at Indiana University between 2003 and 2009 (n = 3...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-0012.2011.01419.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:The objective of this retrospective study was to characterize the neutrophil to lymphocyte ratio (NLR) on the waitlist and determine its prognostic utility in liver transplantation (LT) for hepatocellular carcinoma (HCC) with special focus on longitudinal data. Biomarkers such as pre-operative NLR have been s...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.13743
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Severe systemic hypertension (HTN) is a risk factor for perioperative cardiovascular complications; however, its impact at the time of kidney transplantation (KTX) is not well defined. METHODS:A retrospective cohort study of adult kidney-only transplant recipients between October 2009 and December 2012 was ...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.12579
更新日期:2015-09-01 00:00:00
abstract::Therapeutic living donor nephrectomy is defined as a nephrectomy that is performed as therapy for an underlying medical condition. The patient directly benefits from having their kidney removed, but the kidney is deemed transplantable. The kidney is subsequently used as an allograft for an individual with advanced ren...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.13715
更新日期:2019-12-01 00:00:00
abstract::Cell-mediated responses to xenoantigens are different from those to alloantigens. CD4+ T cells are especially important in xenoresponses and depletion of CD4+ T cells can prolong survival of xenografts better than allografts in some circumstances. The difference between the two responses is due in part to the relative...
journal_title:Clinical transplantation
pub_type: 杂志文章,评审
doi:
更新日期:1994-04-01 00:00:00
abstract:BACKGROUND:In adult living-donor liver transplantation (LDLT), the assessment of the graft functional reserve is very important. We evaluated the graft functional reserve by technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl-human serum albumin ((99m)Tc-GSA) liver scintigraphy. PATIENTS AND METHOD:From May ...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-0012.2008.00933.x
更新日期:2009-03-01 00:00:00
abstract::Citrullinaemia is a rare autosomal recessive disorder due to a deficiency of argininosuccinate synthetase (ASS). While the clinical course of the adult onset form (Type II) is unpredictable, many patients undergo sudden deterioration with progressive cerebral oedema. Two patients with Type II citrullinaemia were refer...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::Transplantation tolerance is the ultimate goal of organ transplantation. Natural regulatory T cells (Treg) have been expected to reach clinical applications for tolerance induction because their initial description. More than ten yr later, Treg have started moving from experimental animal models into clinical applicat...
journal_title:Clinical transplantation
pub_type: 杂志文章,评审
doi:10.1111/j.1399-0012.2009.01103.x
更新日期:2009-12-01 00:00:00
abstract::Differentiating acute pyelonephritis (APN) from acute rejection (AR) in renal allograft biopsies can sometimes be difficult because of overlapping clinical and histologic features, lack of positive urine cultures,and variable response to antibiotics. We wanted to study differential gene expression between AR and APN u...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.12795
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Lung perfusions after single lung transplantation (SLT) have not been fully clarified in patients with interstitial lung disease (ILD). The present study aimed to investigate temporal changes in native lung perfusion and their associated clinical factors in patients with ILD who have undergone SLT. METHODS:...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.12701
更新日期:2016-04-01 00:00:00
abstract::Porto-pulmonary hypertension with moderate or severe pulmonary arterial hypertension (PAH) is viewed as a contraindication to liver transplantation (LT) because of associated poor outcomes; however, patients with biliary atresia (BA) are generally good candidates for LT. Ten patients with moderate/severe PAH underwent...
journal_title:Clinical transplantation
pub_type: 杂志文章
doi:10.1111/ctr.12415
更新日期:2014-09-01 00:00:00