Cell-mediated xenoresponses: strong or weak?

abstract：:Clinical outcomes are generally worse for black vs nonblack renal allograft recipients. In BENEFIT and BENEFIT-EXT, recipients were randomized to belatacept more intense-based, belatacept less intense-based, or cyclosporine-based immunosuppression. At year 7, belatacept was associated with superior graft survival vs c...

journal_title：Clinical transplantation

authors： Florman S,Vincenti F,Durrbach A,Abouljoud M,Bresnahan B,Garcia VD,Mulloy L,Rice K,Rostaing L,Zayas C,Calderon K,Meier-Kriesche U,Polinsky M,Yang L,Medina Pestana J,Larsen CP

更新日期：2018-04-01 00:00:00

abstract：:Obesity has reached epidemic proportions in the USA. Consequently, there are an increasing number of potential organ donors that are obese, but would otherwise be appropriate donors for pancreas transplantation (PTx). This is a retrospective study of all PTx performed at Indiana University between 2003 and 2009 (n = 3...

journal_title：Clinical transplantation

authors： Fridell JA,Mangus RS,Taber TE,Goble ML,Milgrom ML,Good J,Vetor R,Powelson JA

更新日期：2011-05-01 00:00:00

abstract：:These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation will review the current state of the art of donor-derived infections. Specifically, the guideline will summarize standardized definitions and approaches to defining imputability, updated data on the e...

journal_title：Clinical transplantation

authors： Wolfe CR,Ison MG,AST Infectious Diseases Community of Practice.

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Chronic renal failure (CRF) is a common complication of calcineurin inhibitor (CNI)-based immunosuppression following cardiac transplantation (HTx). The aim of this prospective study was to evaluate the impact of an immunosuppressive conversion from CNIs to mycophenolate mofetil (MMF) and steroids in cardiac...

journal_title：Clinical transplantation

authors： Groetzner J,Kaczmarek I,Schirmer J,Uberfuhr P,Gulbins H,Daebritz S,Meiser B,Reichart B

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Renal transplantation is an excellent therapeutic alternative for end-stage renal diseases. Nevertheless, the cardiac function is often impaired in renal-transplant patients (RTR) and importantly determines their prognosis. Adrenomedullin (ADM), a peptide involved in cardiovascular homeostasis, is believed t...

journal_title：Clinical transplantation

authors： Geny B,Ellero B,Chakfé N,Kretz JG,Brandenberger G,Piquard F

更新日期：2006-05-01 00:00:00

abstract：:There is no recommendation regarding the type of induction therapy to use in ABO-incompatible (ABOi) kidney transplantation. The aim of this retrospective study was to compare the outcome of ABOi living donor kidney transplant (LDKT) recipients who received either polyclonal antibodies or anti-interleukin-2 receptor (...

journal_title：Clinical transplantation

authors： Del Bello A,Divard G,Belliere J,Congy-Jolivet N,Lanfranco L,Ricard R,Delas A,Colombat M,Esposito L,Hebral AL,Cointault O,Lefaucheur C,Loupy A,Kamar N

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Aortoiliac pathology in kidney allograft recipients is not rare but treatment timing is controversial. As most publications on this topic are case reports its difficult to evaluate long-term outcomes of those clinical challenges. Herein we report long-term results of these procedures. METHODS:From 1970 to...

journal_title：Clinical transplantation

authors： Tsivian M,Neri F,Nardo B,Bertelli R,Cavallari G,Fuga G,Faenza A

更新日期：2009-03-01 00:00:00

abstract：:The exact mechanism of acute and chronic allograft rejection still remains unclear. The chemokine SDF-1 as mediator of allograft rejection has been under intensive investigation in liver, cardiac and bone marrow transplantation, whereas in renal transplantation, there are no reports about SDF-1 to date. This study was...

journal_title：Clinical transplantation

authors： Hoffmann U,Banas B,Krüger B,Banas M,Bergler T,Böger C,Kammerl M,Obed A,Rümmele P,Segerer S,Riegger GA,Krämer BK

更新日期：2006-11-01 00:00:00

abstract：:The frequent scarcity of organ donors has made it necessary to consider transplantation of organs that may have the potential to transmit hepatitis B virus (HBV) to the recipient. Previous reports have documented the probability of infection of particular recipient populations with transplanted livers from hepatitis B...

journal_title：Clinical transplantation

authors： Dodson SF

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Multidrug-resistant (MDR) gram-negative bacteria are a growing threat to solid organ transplantation (SOT) patients in the intensive care unit (ICU). We aimed to examine the mortality rates of gram-negative MDR bacterial infection in SOT patients compared with patient population undergoing other cardiothorac...

journal_title：Clinical transplantation

authors： Biderman P,Bugaevsky Y,Ben-Zvi H,Bishara J,Goldberg E

更新日期：2015-09-01 00:00:00

abstract：:This paper describes 108 consecutively treated patients receiving 109 cadaveric (CD) and living donor (LD) renal allografts using a protocol of quadruple sequential immunosuppression with a rabbit anti-human thymocyte IgG (Thymoglobuline), azathioprine, tapering corticosteroids, and delayed introduction of cyclosporin...

journal_title：Clinical transplantation

authors： Guttmann RD,Flemming C

更新日期：1997-06-01 00:00:00

abstract：:Pancreas retransplantation has become more frequent and represents a technical challenge for surgeons. Knowledge of alternative surgical options could be useful in difficult cases. We present a case of brutal diabetes mellitus in a patient with severe vascular disease that underwent a third pancreas transplant. Diffic...

journal_title：Clinical transplantation

authors： Garcia-Roca R,Humar A,Sturdevant M,Kobayashi T,Dunn T,Kandaswamy R,Sutherland D

更新日期：2010-05-01 00:00:00

abstract：:We have developed a practical conditioning regimen without anti-thymocyte globulin (ATG), irradiation, or other myeloablative alkylating agent for low-income countries in which patients with severe aplastic anemia (SAA), who usually have heavily transfused and a prolonged disease history. The application of ATG, Busul...

journal_title：Clinical transplantation

authors： Wang SB,Li L,Pan XH,Hu DM,Peng LH,Liu L,Xie ZJ,Yin B,Sun XJ,Yu J,Liang Y

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Numerous studies of steroid withdrawal have been carried out in kidney and liver transplant recipients, but only a few in pancreas transplant recipients. Yet, pancreas transplant recipients could have significant long-term benefits from steroid withdrawal. METHODS:We performed a retrospective analysis to de...

journal_title：Clinical transplantation

authors： Humar A,Parr E,Drangstveit MB,Kandaswamy R,Gruessner AC,Sutherland DE

更新日期：2000-02-01 00:00:00

abstract：:The development of post-transplant lymphoproliferative disorders (PTLD) is a well-recognized complication of solid organ transplantation in patients receiving immunosuppressive therapy. The literature on PTLD in live renal allograft recipients is scarce and most of the data pertains to PTLD in cadaveric transplants. A...

journal_title：Clinical transplantation

authors： Jain M,Badwal S,Pandey R,Srivastava A,Sharma RK,Gupta RK

更新日期：2005-10-01 00:00:00

abstract：INTRODUCTION:Transfusion protocols are not well-studied for pediatric patients with acute liver failure (ALF). This study evaluates the utility of an international normalized ratio (INR)-based transfusion threshold for these patients. METHODS:Forty-four ALF pediatric patients from 2009 to 2018 were reviewed and divide...

journal_title：Clinical transplantation

authors： Lee A,Mendoza J,Brubaker AL,Stoltz DJ,McKenzie R,Bonham CA,Esquivel CO,Gallo AE

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:There are limited published data concerning the effects of different immunosuppressive regimens on the development of polyomavirus (BKV) viremia. We examined the risk of developing BKV viremia in kidney transplant recipients receiving everolimus (EVR) or mycophenolic acid (MPA) as maintenance therapy. METHO...

journal_title：Clinical transplantation

authors： Moscarelli L,Caroti L,Antognoli G,Zanazzi M,Di Maria L,Carta P,Minetti E

更新日期：2013-07-01 00:00:00

abstract：:We performed a systematic search of the literature using the MEDLINE (through 2006) database to identify the patient-reported outcome measures of quality of life (QOL) used most often in the renal transplant literature. After applying limits and reviewing references, we identified 338 renal transplant articles with a ...

journal_title：Clinical transplantation

authors： Butt Z,Yount SE,Caicedo JC,Abecassis MM,Cella D

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder characterized by premature mortal cardiovascular complications. Liver transplantation (LT) is the only curative treatment option. In this study, the long-term clinical follow-up data of 8 patients who underwent LT with a diagnosis o...

journal_title：Clinical transplantation

authors： Gulsoy Kirnap N,Kirnap M,Bascil Tutuncu N,Moray G,Haberal M

更新日期：2019-12-01 00:00:00

abstract：:Chronic allograft nephropathy (CAN) leads to the majority of late graft loss following renal transplantation. Detection of CAN is often too late to permit early intervention and successful management. Most current strategies for managing CAN rely on minimizing or eliminating calcineurin inhibitors (CNIs) once CAN has ...

journal_title：Clinical transplantation

authors： Campistol JM,Boletis IN,Dantal J,de Fijter JW,Hertig A,Neumayer HH,Oyen O,Pascual J,Pohanka E,Ruiz JC,Scolari MP,Stefoni S,Serón D,Sparacino V,Arns W,Chapman JR

更新日期：2009-11-01 00:00:00

abstract：:Because the safety of living organ donors is essential, we have been performing donor kidney biopsy before donation in cases where decision-making regarding suitability is marginal. To clarify the degree to which pathological change in the kidney can be predicted on the basis of clinical data obtained non-invasively, ...

journal_title：Clinical transplantation

authors： Okamoto M,Koshino K,Nobori S,Ushigome H,Okajima H,Urasaki K,Yoshimura N

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:The purpose of our study was to evaluate the diagnostic value of serum galactomannan antigen (GM) testing combined with chest computed tomography (CT) of invasive pulmonary aspergillosis (IPA) in pediatric patients after hematopoietic stem cell transplantation. METHODS:A retrospective nested case-control stu...

journal_title：Clinical transplantation

authors： Qiu KY,Liao XY,Huang K,Xu HG,Li Y,Fang JP,Zhou DH

更新日期：2019-08-01 00:00:00

abstract：:Flow cytometric assay (FCA) was used to detect a cytomegalovirus (CMV) specific antigen (pp65) in CMV-infected fibroblast cells and in leukocytes of kidney recipients. FCA distinguished clearly between the infected and non-infected fibroblast cells. Regarding transplant patients, the FCA was positive when the number o...

journal_title：Clinical transplantation

authors： Essa S,Pacsa AS,Al-Attiyah R,El-Shazly A,Raghupathy R,Said T

更新日期：2000-04-01 00:00:00

abstract：:Granulomatous interstitial nephritis (GIN) is a rare histologic diagnosis in renal allografts. We report three cases with GIN. Case 1: a 37-yr-old woman received a kidney from her mother. On follow-up 15 months later, serum creatinine was increased and a graft biopsy showed epithelioid granuloma in the center of massi...

journal_title：Clinical transplantation

authors： Hotta K,Fukasawa Y,Sasaki H,Seki T,Togashi M,Harada H

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Quantitative analysis of the Epstein-Barr virus (EBV) genome has been recently reported to be helpful for early identification of EBV viremia which could reduce the risk of post-transplantation lymphoproliferative disorder (PTLD). AIM:To demonstrate the significance of serial monitoring of EBV genome load b...

journal_title：Clinical transplantation

authors： Matsukura T,Yokoi A,Egawa H,Kudo T,Kawashima M,Hirata Y,Tanaka H,Kagajo K,Wada H,Tanaka K

更新日期：2002-04-01 00:00:00

abstract：:Considering the relevance of the migratory processes in Western societies, the attitudes toward organ donation after death are analyzed by means of a survey applied to a representative random sample of the resident immigrant population in Spain, comprising 1202 subjects (estimated margin of error of ± 2.88%, p = q, p ...

journal_title：Clinical transplantation

authors： López JS,Valentín MO,Scandroglio B,Coll E,Martín MJ,Sagredo E,Martínez JM,Serna E,Matesanz R

更新日期：2012-05-01 00:00:00

abstract：INTRODUCTION:Recent immunosuppression with tacrolimus and mycophenolate mofetil has improved the results of renal transplantation. In this study, we analyzed the effect and safety of basiliximab as an induction therapy. MATERIAL AND METHODS:Forty-nine kidney recipients were given tacrolimus, mycophenolate mofetil and ...

journal_title：Clinical transplantation

authors： Miura M,Harada H,Fukuzawa N,Iwami D,Taniguchi A,Seki T,Togashi M,Ogawa Y,Satoh H,Hirano T

更新日期：2005-01-01 00:00:00

abstract：:We examined the UNOS database from 7/15/00-7/17/05 for Regional deceased donor liver utilization. For each region, we performed logistic regression and derived odds ratios (OR) for donor characteristics associated with livers being transplanted outside of the region or not transplanted at all. Regions with smallest an...

journal_title：Clinical transplantation

authors： Hayashi PH,Axelrod DA,Galanko J,Salvalaggio PR,Schnitzler M

更新日期：2011-01-01 00:00:00

abstract：:The long-term side effects of lifelong steroid immunosuppression are well documented, therefore, steroid withdrawal (SW) if safe would clearly be of benefit. From 1987-1996, 470 kidney transplants were performed at our institution. During this time period, steroid withdrawal was offered to a select group of patients (...

journal_title：Clinical transplantation

authors： Sanfey H,Haussman G,Isaacs I,Ishitani M,Lobo P,McCullough C,Pruett T

更新日期：1997-10-01 00:00:00

abstract：:Invasive fungal infections are a feared complication in kidney transplant recipients (KTRs). Here we present the University of Wisconsin experience with 5 invasive fungal infections-aspergillosis, cryptococcosis, histoplasmosis, blastomycosis, and coccidioidomycosis-in KTRs transplanted between 01/01/1994 and 06/30/20...

journal_title：Clinical transplantation

authors： Parajuli S,Wick A,Pandeya S,Astor BC,Smith J,Djamali A,Mandelbrot DA

更新日期：2018-07-01 00:00:00