A randomized trial of thymoglobulin vs. alemtuzumab (with lower dose maintenance immunosuppression) vs. daclizumab in renal transplantation at 24 months of follow-up.

abstract：:The concept of a narrow therapeutic window has guided the management of transplant recipients on cyclosporine immunosuppression since its inception more than a decade ago. The need to maintain immunosuppression and avoid toxicity imposed the requirement of monitoring cyclosporine levels within a limited range. The use...

journal_title：Clinical transplantation

authors： Takasugi M,Takasugi JK,Barba L

更新日期：1995-04-01 00:00:00

abstract：:The aging of the on-dialysis population raises the issue of whether to propose elderly patients for kidney transplantation and how to manage their immunosuppression. This study aimed to analyze the outcome of kidney transplantation on an Italian series of elderly recipients. We included in this retrospective study all...

journal_title：Clinical transplantation

authors： Neri F,Furian L,Cavallin F,Ravaioli M,Silvestre C,Donato P,La Manna G,Pinna AD,Rigotti P

更新日期：2017-10-01 00:00:00

abstract：:Obese transplant recipients (BMI ≥ 30 kg/m2 ) have decreased posttransplant patient and graft survival compared with their nonobese counterparts. At the same time, many prednisone-related side effects (eg, new-onset diabetes) are similar to those associated with obesity. Using SRTR data, we studied outcomes associated...

journal_title：Clinical transplantation

authors： Matas AJ,Vock DM

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:To assess the diagnostic value of magnetic resonance cholangiography (MRC) when evaluating biliary complications in a large series of liver transplants. METHODS:One hundred and twenty-nine patients prospectively underwent magnetic resonance (MR) imaging and MR cholangiography at 1.5-T device after orthotopi...

journal_title：Clinical transplantation

authors： Boraschi P,Donati F,Gigoni R,Volpi A,Salemi S,Filipponi F,Falaschi F

更新日期：2010-07-01 00:00:00

abstract：:In this single-institution study, we compared outcomes in diabetic recipients of living donor (LD) kidney transplants that did vs. did not undergo a subsequent pancreas transplant. Of 307 diabetic recipients who underwent LD kidney transplants from January 1, 1995, through December 31, 2003, a total of 175 underwent a...

journal_title：Clinical transplantation

authors： Kleinclauss F,Fauda M,Sutherland DE,Kleinclauss C,Gruessner RW,Matas AJ,Kasiske BL,Humar A,Kandaswamy R,Kaul S,Gruessner AC

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Angiotensin converting enzyme (ACE) inhibitors have been successfully used for treatment of proteinuria after renal transplantation (RTx). Factors possibly responsible for the great inter-patient variance of the antiproteinuric effect (APE) have not yet been investigated in renal-transplanted patients. METH...

journal_title：Clinical transplantation

authors： Lufft V,Kliem V,Hamkens A,Bleck JS,Eisenberger U,Petersen R,Ehlerding G,Maschek H,Pichlmayr R,Brunkhorst R

更新日期：1998-10-01 00:00:00

abstract：:Patients with failing Fontan physiology and liver cirrhosis are being considered for combined heart and liver transplantation. We performed a retrospective review of our experience with en bloc combined heart and liver transplantation in Fontan patients > 10 years old from 2006 to 18 per Institutional Review Board app...

journal_title：Clinical transplantation

authors： Vaikunth SS,Concepcion W,Daugherty T,Fowler M,Lutchman G,Maeda K,Rosenthal DN,Teuteberg J,Woo YJ,Lui GK

更新日期：2019-06-01 00:00:00

abstract：:The current pandemic SARS-CoV-2 has required an unusual allocation of resources that can negatively impact chronically ill patients and high-complexity procedures. Across the European Reference Network on Pediatric Transplantation (ERN TransplantChild), we conducted a survey to investigate the impact of the COVID-19 o...

journal_title：Clinical transplantation

authors： Doná D,Torres Canizales J,Benetti E,Cananzi M,De Corti F,Calore E,Hierro L,Ramos Boluda E,Melgosa Hijosa M,Garcia Guereta L,Pérez Martínez A,Barrios M,Costa Reis P,Teixeira A,Lopes MF,Kaliciński P,Branchereau S,Boyer O

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:As Gastroesophageal reflux disease (GORD) affects long-term survival in lung transplant recipients, the aim of this observational prospective study was to analyze the efficacy of The Reflux Symptom Index Questionnaire (RSI) compared to the esophageal impedance test. METHODS:Both esophageal impedance studies ...

journal_title：Clinical transplantation

authors： Soresi S,Zeriouh M,Sabashnikov A,Mc Dermott G,Weymann A,Wippermann J,Wahlers T,Reed A,Carby M,Simon AR,Popov AF

更新日期：2016-01-01 00:00:00

abstract：:Tuberculosis remains one of the most serious infections after organ transplantation. Isoniazid prophylaxis for liver transplant recipients with a history of tuberculosis is generally recommended. However, its benefit is controversial because of potential hepatotoxicity of isoniazid. It is crucial to determine appropri...

journal_title：Clinical transplantation

authors： Nagai S,Fujimoto Y,Taira K,Egawa H,Takada Y,Kiuchi T,Tanaka K

更新日期：2007-03-01 00:00:00

abstract：:The infectious disease coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization in March 2020. The impact of COVID-19 on solid organ transplantations, including heart transplantation, is currently unclear. Many transplant programs have been forced to swiftly re-evaluate and adapt th...

journal_title：Clinical transplantation

authors： Hsu JJ,Al-Saffar F,Ardehali R,Baas AS,Carlson M,Cruz D,Deng M,Fan A,Fraschilla S,Gaynor P,Kamath M,Kubak BM,Schaenman J,Stimpson E,Vucicevic D,Ardehali A,Nsair A

更新日期：2020-09-01 00:00:00

abstract：:Tacrolimus (TAC) is a calcineurin inhibitor that is used for cardiac allograft rejection. Efficacy and safety data of a combined TAC/mycophenolate mofetil (MMF) therapy in comparison with a TAC/cortisone therapy in heart recipients are lacking. We analysed the clinical outcome of 41 patients who received TAC in combin...

journal_title：Clinical transplantation

authors： Fuchs U,Tenderich G,Zittermann A,Szabados F,Minami K,Koerfer R

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:The colloid-based University of Wisconsin (UW) preservation solution has been used extensively in clinical pancreas transplantation. Experimental studies support the use of the crystalloid-based histidine-tryptophan-ketoglutarate (HTK) preservation solution for this purpose. AIM:We report our initial experi...

journal_title：Clinical transplantation

authors： Potdar S,Malek S,Eghtesad B,Shapiro R,Basu A,Patel K,Broznick B,Fung J

更新日期：2004-12-01 00:00:00

abstract：:Sezer S, Ozdemir FN, Akcay A, Arat Z, Boyacioglu S, Haberal M. Renal transplantation offers a better survival in HCV-infected ESRD patients. Clin Transplant 2004 DOI: 10.1111/j.1399-0012.2004.00252. Abstract: The presence of hepatitis C virus (HCV) infection has been found to adversely affect the morbidity and mortali...

journal_title：Clinical transplantation

authors： Sezer S,Ozdemir FN,Akcay A,Arat Z,Boyacioglu S,Haberal M

更新日期：2004-10-01 00:00:00

abstract：:As there are other lesions in the cardiac allografts of long-term survivors, it is best to refer to the vascular lesion as "graft vascular disease". Graft vascular disease may be evident as early as 3 months after cardiac transplantation and may cause death in the recipient as late as 22 years post-transplant. The dis...

journal_title：Clinical transplantation

authors： Billingham ME

更新日期：1994-06-01 00:00:00

abstract：:Because the safety of living organ donors is essential, we have been performing donor kidney biopsy before donation in cases where decision-making regarding suitability is marginal. To clarify the degree to which pathological change in the kidney can be predicted on the basis of clinical data obtained non-invasively, ...

journal_title：Clinical transplantation

authors： Okamoto M,Koshino K,Nobori S,Ushigome H,Okajima H,Urasaki K,Yoshimura N

更新日期：2010-07-01 00:00:00

abstract：:Sarcopenia frequently occurs in cirrhotic patients who are waiting for liver transplantation (LT). This disease is associated with increased morbidity and mortality rates during the LT period. Recently, the careful assessment of nutritional status for end-stage liver disease patients has received a great deal of atten...

journal_title：Clinical transplantation

authors： Nam NH,Kaido T,Uemoto S

更新日期：2019-12-01 00:00:00

abstract：:Liver transplantation for hepatitis B virus (HBV)-related liver disease has changed from a contraindication to outcomes comparable with non-HBV-related liver transplantations during the last two decades. Mainly the implementation of immunoprophylaxis with hepatitis B immunoglobulin (HBIG) and the use of nucleoside ana...

journal_title：Clinical transplantation

authors： Eisenbach C,Sauer P,Mehrabi A,Stremmel W,Encke J

更新日期：2006-01-01 00:00:00

abstract：:These updated guidelines from the American Society of Transplantation Infectious Diseases Community of Practice provide recommendations for the diagnosis and management of Candida infections in solid organ transplant recipients. Candida infections manifest primarily as candidemia and invasive candidiasis and cause con...

journal_title：Clinical transplantation

authors： Aslam S,Rotstein C,AST Infectious Disease Community of Practice.

更新日期：2019-09-01 00:00:00

abstract：:Flow cytometry crossmatch (FCXM) is a more sensitive technique than classical complement-dependent cytotoxicity (CDC) for the detection of donor-directed antibody before renal transplantation. Nevertheless, the role of FCXM in predicting long-term survival of kidney grafts is still unclear. The purpose of our study wa...

journal_title：Clinical transplantation

authors： Rebibou JM,Bittencourt MC,Saint-Hillier Y,Chabod J,Dupont I,Bittard H,Chalopin JM,Hervé P,Tiberghien P

更新日期：2004-10-01 00:00:00

abstract：:Calcineurin inhibitors (CNI) are the mainstay of immunosuppression after liver transplantation (LT), but CNIs are associated with significant nephrotoxicity. Recently, mTOR inhibitors such as sirolimus and everolimus (EVR) have been used with or without CNIs in LT recipients for their renal-sparing effect. We conducte...

journal_title：Clinical transplantation

authors： Lin M,Mittal S,Sahebjam F,Rana A,Sood GK

更新日期：2017-02-01 00:00:00

abstract：:Research with human transplant recipients has shown that mycophenolate mofetil (MMF) is a powerful and selective immunosuppressant for maintenance therapy following renal transplantation. An additional body of work suggests that it might also be a valuable tool for arresting ongoing rejection episodes. One randomized,...

journal_title：Clinical transplantation

authors：

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Numerous studies of steroid withdrawal have been carried out in kidney and liver transplant recipients, but only a few in pancreas transplant recipients. Yet, pancreas transplant recipients could have significant long-term benefits from steroid withdrawal. METHODS:We performed a retrospective analysis to de...

journal_title：Clinical transplantation

authors： Humar A,Parr E,Drangstveit MB,Kandaswamy R,Gruessner AC,Sutherland DE

更新日期：2000-02-01 00:00:00

abstract：:Distinct histopathologic changes occur in acute cellular rejection (ACR), antibody-mediated rejection (AMR), and biopsy-negative rejection (BNR). Cardiovascular magnetic resonance (CMR)-based myocardial tissue characterization can be used to quantify these changes. We assessed T1, T2, and extracellular volume fraction...

journal_title：Clinical transplantation

authors： Miller RJH,Thomson L,Levine R,Dimbil SJ,Patel J,Kobashigawa JA,Kransdorf E,Li D,Berman DS,Tamarappoo B

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Thrombosis of the pancreas after transplantation is the most common cause of relaparotomy and resultant graft loss. There is currently no standard protocol consistently proven to prevent thrombosis following transplantation. Our objective was to determine whether our protocol of post-operative low-dose int...

journal_title：Clinical transplantation

authors： Aboalsamh G,Anderson P,Al-Abbassi A,McAlister V,Luke PP,Sener A

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Lung perfusions after single lung transplantation (SLT) have not been fully clarified in patients with interstitial lung disease (ILD). The present study aimed to investigate temporal changes in native lung perfusion and their associated clinical factors in patients with ILD who have undergone SLT. METHODS:...

journal_title：Clinical transplantation

authors： Sokai A,Handa T,Chen F,Tanizawa K,Aoyama A,Kubo T,Ikezoe K,Nakatsuka Y,Oguma T,Hirai T,Nagai S,Chin K,Date H,Mishima M

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:In adult living-donor liver transplantation (LDLT), the assessment of the graft functional reserve is very important. We evaluated the graft functional reserve by technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl-human serum albumin ((99m)Tc-GSA) liver scintigraphy. PATIENTS AND METHOD:From May ...

journal_title：Clinical transplantation

authors： Iida T,Isaji S,Yagi S,Hori T,Taniguchi K,Ohsawa I,Mizuno S,Usui M,Sakurai H,Yamagiwa K,Yamakado K,Uemoto S

更新日期：2009-03-01 00:00:00

abstract：:Cell-mediated responses to xenoantigens are different from those to alloantigens. CD4+ T cells are especially important in xenoresponses and depletion of CD4+ T cells can prolong survival of xenografts better than allografts in some circumstances. The difference between the two responses is due in part to the relative...

journal_title：Clinical transplantation

authors： Auchincloss H Jr

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Intra-abdominal fibromatosis often involves the mesentery root which is non-resectable by conventional surgery. Multivisceral transplant (MVT), as a potential cure to non-resectable fibromatosis, has rarely been reported and the prognosis is unknown. METHODS:Six patients who underwent MVT for intra-abdomina...

journal_title：Clinical transplantation

authors： Chi Z,Mangus RS,Kubal CA,Chen S,Lin J

更新日期：2018-03-01 00:00:00

abstract：:Chronic allograft nephropathy (CAN) is a major problem after renal transplantation and chronic inflammation can be one of its promoters. C-reactive protein (CRP) is an important marker of inflammation and atherosclerosis. We retrospectively analyzed the predictive role of serum CRP levels on the development of CAN and...

journal_title：Clinical transplantation

authors： Sezer S,Akcay A,Ozdemir FN,Kulah E,Arat Z,Haberal M

更新日期：2004-12-01 00:00:00