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The human immunodeficiency virus-reverse transcriptase inhibition activity of novel pyridine/pyridinium-type fullerene derivatives.

Abstract：

:In the present study, we describe the synthesis of a novel set of pyridine/pyridinium-type fullerene derivatives. The products were assessed for human immunodeficiency virus-reverse transcriptase inhibition activities. All novel fullerene derivatives showed potent human immunodeficiency virus-reverse transcriptase inhibition without cytotoxicity.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Yasuno T,Ohe T,Takahashi K,Nakamura S,Mashino T

doi

10.1016/j.bmcl.2015.05.086

subject

Has Abstract

pub_date

2015-08-15 00:00:00

pages

3226-9

issue

16

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(15)00560-0

journal_volume

25

pub_type

杂志文章

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