Novel vaccine concept based on back-boost effect in viral infection.

Abstract:

:A novel vaccine concept is discussed based on recent evidence of a "back-boost" effect in Influenza infection. The initial immune response to the infection is imprinted through an immune memory pathway. The immune memory in the back-boost mechanism could be used in reversed order as a "forward-boost" in the proposed vaccine concept.

journal_name

Vaccine

journal_title

Vaccine

authors

Kohler H

doi

10.1016/j.vaccine.2015.05.035

subject

Has Abstract

pub_date

2015-06-26 00:00:00

pages

3274-5

issue

29

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(15)00687-8

journal_volume

33

pub_type

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