Abstract:
INTRODUCTION:The diagnostic accuracy of Xpert MTB/RIF (Xpert) in pulmonary tuberculosis (PTB) in children is lower than in adults. In Brazil, the diagnosis of PTB is based on a diagnostic score system (DSS). This study aims to study the role of Xpert in children and adolescents with PTB symptoms. METHODS:cross-sectional study was conducted in 3 referral centers to TB. Children and adolescents (0-19 years old) whose respiratory samples were submitted to Xpert were included. Statistical analysis (bivariate and logistic regression) to assess the simultaneous influence of TB-related variables on the occurrence of Xpert detectable in TB cases was done. To evaluate the agreement or disagreement between Xpert results with acid-fast bacillus (AFB) and cultures, κ method was used (significancy level of 5%). RESULTS:Eighty-eight patients were included in the study and PTB occurred in 43 patients (49%) and Xpert was detectable in 21 patients (24%). Adolescents and positive culture results were independent predictive variables of Xpert positivity. DSS sensitivity compared with the final diagnosis of TB was 100% (95% CI, 88.1-100%), specificity was 97.2% (95% CI, 85.5-99.9%). The accuracy of the method was 98.5% (95% CI, 91.7-99.9%). CONCLUSIONS:Xpert contributed to diagnosis in 9% of patients with AFB and in culture negative cases. DSS indicated relevance for this diagnostic approach of intrathoracic TB (ITB) in reference centers for presenting data both with high sensitivity and specificity.
journal_name
Rev Soc Bras Med Tropjournal_title
Revista da Sociedade Brasileira de Medicina Tropicalauthors
Aurilio RB,Luiz RR,Land MGP,Cardoso CAA,Kritski AL,Sant'Anna CCdoi
10.1590/0037-8682-0205-2020subject
Has Abstractpub_date
2020-09-25 00:00:00pages
e20200205eissn
0037-8682issn
1678-9849pii
S0037-86822020000100351journal_volume
53pub_type
杂志文章abstract:INTRODUCTION:Crotalus envenomations cause serious complications and can be fatal without appropriate treatment. Venom isoforms present and inter/intraspecific variations in the venom composition can result in different symptoms presented by bites by snakes from the same species but from different geographical regions. ...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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更新日期:2019-09-05 00:00:00
abstract:INTRODUCTION:Favorable responses in American tegumentary leishmaniasis (ATL) patients to treatment with 5 mg Sbv/kg/day meglumine antimoniate (MA) has been reported in Rio de Janeiro, but little is known regarding the therapeutic response to low doses in patients from other locations. METHODS:A retrospective review of...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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doi:10.1590/0037-8682-0464-2017
更新日期:2018-11-01 00:00:00
abstract::Some epidemiological characteristics of head lice, Pediculus capitis, were studied using two procedures: cut hair analysis and head inspection. Higher prevalence rates were observed in the middle and at the end of the school terms. Both procedures indicated that children were the main reservoir for this type of pedicu...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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doi:10.1590/s0037-86822007000200022
更新日期:2007-03-01 00:00:00
abstract::Lymphogranuloma venereum (LGV) is an uncommon, contagious, sexually transmitted disease (STD). We report a case of a 17-year-old teenager who presented with a 2-month-old ulcerous vegetant lesion in the right inguinal region. The patient was diagnosed with LGV and received erythromycin treatment. Three months after tr...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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doi:10.1590/s0037-86822012000300029
更新日期:2012-06-01 00:00:00
abstract:INTRODUCTION:We report the larvicidal activity of two formulations from Amanita muscariaagainst Culex quinquefasciatus, as well as the viability of the aqueous extract after storage. METHODS The larvicidal activity of aqueous extract and powder from A. muscaria, and the viability of the aqueous extract after storage, w...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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doi:10.1590/0037-8682-0175-2015
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abstract:INTRODUCTION:This study aimed to analyze social factors involved in the spatial distribution and under-reporting of tuberculosis (TB) in the city of Vitória, Espírito Santo State, Brazil. METHODS:This was an ecological study of the reported cases of TB between 2009 and 2011, according to census tracts. The outcome was...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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doi:10.1590/0037-8682-0015-2018
更新日期:2018-09-01 00:00:00
abstract:INTRODUCTION:Hepatitis B virus (HBV) constitutes an important risk factor for cirrhosis and hepatocellular carcinoma (HCC). The link between circulating microRNAs and HBV has been previously reported, although not as a marker of liver disease progression in chronic hepatitis B (CHB). The aim of this study was to charac...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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doi:10.1590/0037-8682-0416-2016
更新日期:2017-03-01 00:00:00
abstract:INTRODUCTION:The increase in American tegumentary leishmaniasis (ATL) cases in 2005 was due to an outbreak that occurred in the towns of Itapema and Balneário Camboriú. This study aimed to determine the possible presence of infection by Leishmania sp in domestic dogs living in an endemic focus of ATL in the town of Bal...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822010000600023
更新日期:2010-11-01 00:00:00
abstract::This review has three objectives: a) To stimulate further research of this prevalent human infection b) to examine the progress of current diagnostic techniques and c) to emphasise the significance of the flagellate parasite Trypanosoma (Herpetosoma) rangeli in Chagas' Disease endemic areas of South and Central Americ...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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更新日期:1998-03-01 00:00:00
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822007000600012
更新日期:2007-11-01 00:00:00
abstract::During the period October 1992 to July 1995 we measured the osmolarity and pH of ampoules of meglumine antimoniate (glucantime) from lot 9206L-004 (manufactured by Rhodia Farma Ltd, of São Paulo, SP, Brazil) maintained in three temperature conditions namely 4 degrees C, 37 degrees C and ambiental. Although we observed...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86821996000500009
更新日期:1996-09-01 00:00:00
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/0037-8682-0026-2017
更新日期:2018-01-01 00:00:00
abstract::The author presents his personal point of view on the present situation of Chagas' disease control in Latin America countries. He compares the situation with African trypanosomiasis. He comments on the existence of cases in other Continents. He emphasizes the success of the fighting against domiciliated triatomine bug...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章,评审
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更新日期:1997-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2010-09-01 00:00:00
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822009000300003
更新日期:2009-05-01 00:00:00
abstract:INTRODUCTION:Aedes albopictus was first detected in Brazil in 1986. This mosquito species presents a major threat to public health because Brazilian populations have shown substantial vector competence for arboviruses such as dengue and chikungunya. METHODS:We updated the records of Ae. albopictus in several States of...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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更新日期:2015-01-01 00:00:00
abstract::The polypeptides of 46 and 58 kDa were recognized in different T. cruzi strains (Y, WSL and Colombiana) by serum of all chagasic patients studied. These polypeptides were isolated from T. cruzi Y strain and used in ELISA. The sensitivity and specificity were 97.6% [CI 95%: 86-100%] and 100% [CI 95%: 89.3-100%], respec...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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doi:10.1590/s0037-86822000000400006
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abstract:INTRODUCTION:Epidemiological data on the prevalence of extended-spectrum β-lactamases (ESBLs) are scarce in Brazil despite the fact that these data are essential for empirical treatment and control measures. The objective of this study was to evaluate the prevalence of different ESBLs by type and distribution in a tert...
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
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更新日期:2012-03-01 00:00:00
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822007000400006
更新日期:2007-07-01 00:00:00
abstract::Frequency of seropositivity for Toxocara in children from different socioeconomic strata in the city of Brasilia (Brazil) was measured. Six hundred and two children of both sexes, aged one to 12 years were distributed in two socioeconomically distinct groups. The samples of sera of the first group were obtained from b...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
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更新日期:2015-11-01 00:00:00
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/0037-8682-0086-2014
更新日期:2014-07-01 00:00:00
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86822009000100015
更新日期:2009-01-01 00:00:00
abstract::A case of larva migrans or serpiginous linear dermatitis on the scalp of a teenager is reported. An ancylostomid larva was found within a sebaceous gland acinus. The unusual skin site for larva migrans as well as the penetration through the sebaceous gland are highlighted. The probable mechanism by which the parasite ...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章,评审
doi:10.1590/s0037-86821999000200011
更新日期:1999-03-01 00:00:00
abstract::The efficacy of azithromycin and pyrimethamine in experimental infection of mice with Toxoplasma gondii was tested. Daily dosages of 200 mg/kg and 12.5 mg/kg, respectively, were given orally over a period of ten days. The medications were administered in combination or separately. The combined use of the drugs yielded...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
doi:10.1590/s0037-86821999000400011
更新日期:1999-07-01 00:00:00
abstract::Chronic chagasic cardiomyopathy remains a major cause of death due to heart failure in Latin American countries and for which there is currently no effective treatment. While chagasic patients wait for the development of more efficient and less toxic chemotherapeutics for the elimination of Trypanosoma cruzi, a new st...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章,评审
doi:10.1590/s0037-86822004000600012
更新日期:2004-11-01 00:00:00