Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction.

Abstract:

:Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be localized or disseminated by contiguity or vascular invasion. We report a severe case of rhinosinusitis with cutaneous involvement, caused by invasive aspergillosis, in an immunocompetent user of inhaled cocaine. Invasive aspergillosis related to cocaine abuse has not yet been reported in the literature. After itraconazole treatment and surgical debridement, complete clinical remission was achieved. Nasal reconstruction with a skin graft over a silicone prosthesis resulted in a satisfactory esthetic outcome.

journal_name

Rev Soc Bras Med Trop

authors

Azulay-Abulafia L,Sousa MA,Pussanti A,Coimbra DD,Vega H,Bernardes Filho F

doi

10.1590/0037-8682-0086-2014

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

533-6

issue

4

eissn

0037-8682

issn

1678-9849

pii

S0037-86822014000400533

journal_volume

47

pub_type

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