A breakthrough in probiotics: Clostridium butyricum regulates gut homeostasis and anti-inflammatory response in inflammatory bowel disease.

abstract：:Despite the numerous efforts of randomized studies on advanced gastric cancer, no globally accepted standard regimen has yet been established. Two triplet regimens have already demonstrated significant survival prolongation in Western studies. However, the benefit seems to be marginal, and these regimens may be replac...

journal_title：Journal of gastroenterology

authors： Ohtsu A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Vaniprevir is a potent macrocyclic hepatitis C virus (HCV) nonstructural protein 3/4A protease inhibitor. This phase III study evaluated the safety and efficacy of vaniprevir in combination with peginterferon alfa-2b and ribavirin (PR) for 24 weeks compared with PR alone for 48 weeks in treatment-naive Japan...

journal_title：Journal of gastroenterology

authors： Hayashi N,Nakamuta M,Takehara T,Kumada H,Takase A,Howe AY,Ludmerer SW,Mobashery N

更新日期：2016-04-01 00:00:00

abstract：:Black liver is a common finding in Dubin-Johnson syndrome (DJS), which is caused by the lack of multidrug resistance-associated protein 2 (MRP2). Impaired excretion of epinephrine metabolites is believed to be a cause of black liver in DJS. Recently, we experienced a patient with black liver whose serum bilirubin leve...

journal_title：Journal of gastroenterology

authors： Kobayashi Y,Ishihara T,Wada M,Kajihara S,Araki J,Mifuji R,Itani T,Kuroda M,Urawa F,Kaito M,Adachi Y

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:There have only been a few prospective studies investigating risk factors associated with the development of hepatocellular carcinoma (HCC) among chronic hepatitis B patients all over the world, and no study has been conducted in Japanese population. METHODS:A population-based cohort consisting of 19393 sub...

journal_title：Journal of gastroenterology

authors： Kusakabe A,Tanaka Y,Inoue M,Kurbanov F,Tatematsu K,Nojiri S,Joh T,Tsugane S,Mizokami M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Esophageal squamous cell carcinoma (ESCC) is a common cancer type in China. In this study, we aimed to develop aneuploidy markers for diagnosis and prognosis of ESCC. METHODS:Chromosomal aneuploidies were detected in 493 primary tumors and 61 precancerous lesions by fluorescence in situ hybridization with c...

journal_title：Journal of gastroenterology

authors： Hao JJ,Yao HQ,Dai GY,Kang W,Jia XM,Xu X,Cai Y,Zhan QM,Wang GQ,Wang MR

更新日期：2015-02-01 00:00:00

abstract：:A 65-year-old woman was admitted to our hospital with the diagnosis of gallbladder tumor. Right extended hepatic lobectomy plus lymph node dissection of the hepatoduodenal ligament and left hepaticojejunostomy with Roux-en-Y reconstruction was performed in July, 1993. The gallbladder tumor was histologically proven to...

journal_title：Journal of gastroenterology

authors： Suganuma M,Marugami Y,Sakurai Y,Ochiai M,Hasegawa S,Imazu H,Matsubara T,Funabiki T,Kuroda M

更新日期：1997-12-01 00:00:00

abstract：:Positron emission tomography (PET) is widely available and its application with 2-[(18)F] fluoro-2-deoxy-D-glucose ((18)F-FDG) in oncology has become one of the standard imaging modalities in diagnosing and staging of tumors, and monitoring the therapeutic efficacy in hepatic malignancies. Recently, investigators have...

journal_title：Journal of gastroenterology

authors： Tsurusaki M,Okada M,Kuroda H,Matsuki M,Ishii K,Murakami T

更新日期：2014-01-01 00:00:00

abstract：:There have been numerous reports that mucinous cystadenoma of the pancreas can transform to mucinous cystadenocarcinoma after cystenterostomy, but few authors have reported morphological changes long after cystenterostomy for mucinous cystadenoma. A 41-year-old Japanese woman had undergone cystgastrostomy at a nearby ...

journal_title：Journal of gastroenterology

authors： Masatsugu T,Yamaguchi K,Arima T,Chijiiwa K,Tanaka M

更新日期：2002-01-01 00:00:00

abstract：:In a pilot study of direct dissolution therapy of gallstones with methyl tert-butyl ether (MTBE), endoscopic transpapillary catheterization in the gallbladder (ETCG) was performed. Complete dissolution was seen in 8 out of 12 (66%) patients and partial dissolution was seen in 2 (16%) patients. In one of the 8 complete...

journal_title：Journal of gastroenterology

authors： Uchida N,Nakatsu T,Hirabayashi S,Minami A,Fukuma H,Ezaki T,Morshed SA,Fuke C,Ameno K,Ijiri I

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Liver histology is the gold standard for the diagnosis of nonalcoholic steatohepatitis (NASH). Noninvasive, simple, reproducible, and reliable biomarkers are greatly needed to differentiate NASH from nonalcoholic fatty liver disease (NAFLD). METHODS:To construct a scoring system for predicting NASH, 177 Jap...

journal_title：Journal of gastroenterology

authors： Sumida Y,Yoneda M,Hyogo H,Yamaguchi K,Ono M,Fujii H,Eguchi Y,Suzuki Y,Imai S,Kanemasa K,Fujita K,Chayama K,Yasui K,Saibara T,Kawada N,Fujimoto K,Kohgo Y,Okanoue T,Japan Study Group of Nonalcoholic Fatty Liver Disease

更新日期：2011-02-01 00:00:00

abstract：:Involvement of the gastroduodenum is extremely rare in Crohn's disease. For obstructing duodenal Crohn's disease, bypass procedures have traditionally been selected. However, more recently, strictureplasty has become an acceptable surgical option. We treated two Crohn's disease patients with short proximal duodenal st...

journal_title：Journal of gastroenterology

authors： Takesue Y,Yokoyama T,Akagi S,Ohge H,Murakami Y,Imamura Y,Uemura K,Kanehiro T,Matsuura Y

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Musashi-1 (Msi-1) is a RNA-binding protein, known as a putative marker of intestinal stem cells (ISCs). However, little is known about the function of Msi-1 within human intestinal epithelial cells (IECs). Thus, the present study aimed to clarify the role of Msi-1 in differentiation and proliferation of IECs...

journal_title：Journal of gastroenterology

authors： Murayama M,Okamoto R,Tsuchiya K,Akiyama J,Nakamura T,Sakamoto N,Kanai T,Watanabe M

更新日期：2009-01-01 00:00:00

abstract：:Although stomal varices are a rare complication, bleeding stomal varices often need to be treated owing to symptoms of hypovolemic shock, recurrence of stomal bleeding, or deterioration in the quality of life. Various treatment strategies for the management of bleeding stomal varices have thus far been reported. We re...

journal_title：Journal of gastroenterology

authors： Minami S,Okada K,Matsuo M,Kamohara Y,Sakamoto I,Kanematsu T

更新日期：2007-01-01 00:00:00

abstract：:In recent years autoimmune pancreatitis (AIP) has been established as a special type of chronic pancreatitis. It is characterized by its histopathological and immunological features. The morphological hallmarks are periductal infiltration by lymphocytes and plasma cells, granulocytic epithelial lesions with focal dest...

journal_title：Journal of gastroenterology

authors： Klöppel G,Sipos B,Zamboni G,Kojima M,Morohoshi T

更新日期：2007-05-01 00:00:00

abstract：:Two hundred and three patients with Crohn's disease seen at Kyushu University, Fukuoka University, and their affiliated centers from 1973 to 1988 were followed for 4.4 +/- 3.2 years (mean +/- SD), to evaluate the prognosis relative to life span and surgery. Cumulative survival rate and cumulative operation rate were c...

journal_title：Journal of gastroenterology

authors： Iida M,Yao T,Okada M

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Circular RNAs (circRNAs) act as vital regulators of gene expression in a variety of cancers. However, the role of circRNAs in gastric cancer (GC) remains largely unexplored. Herein, we identified that circTMEM87A sponges miR-142-5p to promote GC progression through up-regulating ULK1 expression. METHODS:The...

journal_title：Journal of gastroenterology

authors： Wang H,Sun G,Xu P,Lv J,Zhang X,Zhang L,Wang S,Cao J,Xia Y,Xuan Z,Li B,Huang X,Jiang T,Fang L,Xu Z

更新日期：2020-11-06 00:00:00

abstract：BACKGROUND:Ghrelin, an appetite-promoting peptide secreted from the stomach, is reported to enhance preprandial acid output, possibly through stimulation of the cephalic phase. The present study was designed to clarify the dynamics of ghrelin in H(2) receptor (H(2)R)-null mice by genetic H(2)R knockout. METHODS:Fiftee...

journal_title：Journal of gastroenterology

authors： Arakawa M,Suzuki H,Minegishi Y,Fukushima Y,Masaoka T,Ishikawa T,Hosoda H,Kangawa K,Hibi T

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Previous studies investigating the impact of tumor location on colorectal cancer prognosis only compared two groups by location, e.g., 'right-sided colon vs. left-sided colon,' 'colon vs. rectum,' and 'right-sided (right-sided colon) vs. left-sided (left-sided colon and rectum).' This nationwide multicenter ...

journal_title：Journal of gastroenterology

authors： Shida D,Inoue M,Tanabe T,Moritani K,Tsukamoto S,Yamauchi S,Sugihara K,Kanemitsu Y

更新日期：2020-10-01 00:00:00

abstract：:We report two cirrhotic patients with gastric antral vascular ectasia (GAVE) in whom chronic blood loss presented a major problem. Case 1, a 69-year-old man, had alcoholic liver cirrhosis, and case 2, a 75-year-old woman, had liver cirrhosis associated with hepatitis C virus. The patients required repeated blood trans...

journal_title：Journal of gastroenterology

authors： Yamada M,Nishimura D,Hoshino H,Katada N,Sano H,Kato K

更新日期：1998-08-01 00:00:00

abstract：:We report a 74-year-old man with triple synchronous cancers occurring in the gallbladder, common bile duct, and pancreas. The patient had consulted a nearby physician because of epigastralgia and icterus. On September 30, 1997, the patient was admitted to our department for further evaluation and treatment. Abdominal ...

journal_title：Journal of gastroenterology

authors： Sato K,Maekawa T,Yabuki K,Tamasaki Y,Maekawa H,Kudo K,Sengoku H,Kawa I,Wada R,Matsumoto M

更新日期：2003-01-01 00:00:00

abstract：:We describe a gastric carcinoma cell line that has been maintained in vitro for more than 10 years and retains the capacity to produce a large amount of alpha-fetoprotein. This cell line was isolated from a metastatic lymph node of a 63-year-old male patient with advanced gastric carcinoma (T2N3P0H0M0) who showed high...

journal_title：Journal of gastroenterology

authors： Sekiguchi M,Fujii Y,Saito A,Suzuki T,Shiroko Y,Nakamura H,Hasumi K

更新日期：1995-10-01 00:00:00

abstract：:Perianal fistulae are frequently seen complications in Crohn's disease. Although surgical procedures such as Seton's method have been devised, many patients still suffer from fistulae that are resistant to conventional therapy. We administered oral adsorbent to a patient with disease Crohn's who had a complicated peri...

journal_title：Journal of gastroenterology

authors： Tsujikawa T,Araki Y,Makino J,Uda K,Ihara T,Sasaki M,Fujiyama Y,Bamba T

更新日期：2000-01-01 00:00:00

abstract：:Helicobacter pylori infection has been found to decrease the expression of antral somatostatin and to increase the release of the acid-stimulating hormone gastrin. The reversal of these changes in gut hormones by the eradication of H. pylori, and in-vivo and in-vitro studies in animals either infected with H. pylori o...

journal_title：Journal of gastroenterology

authors： Kaneko H,Konagaya T,Kusugami K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:We carried out this study to evaluate recent clinical features of Wilson's disease (WD) with hepatic presentation, especially in terms of age, degree of liver injury, and association with hepatocellular carcinoma (HCC). METHODS:Sixteen patients with hepatic manifestations were diagnosed with WD in the perio...

journal_title：Journal of gastroenterology

authors： Kumagi T,Horiike N,Michitaka K,Hasebe A,Kawai K,Tokumoto Y,Nakanishi S,Furukawa S,Hiasa Y,Matsui H,Kurose K,Matsuura B,Onji M

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The Japan Society of Diabetes Mellitus reported that the leading cause of death in patients with diabetes mellitus (DM) was chronic liver disease; however, there are limited studies investigating the cause of liver injury in these patients. Our study aimed to clarify the clinicopathological features of liver...

journal_title：Journal of gastroenterology

authors： Shima T,Uto H,Ueki K,Takamura T,Kohgo Y,Kawata S,Yasui K,Park H,Nakamura N,Nakatou T,Tanaka N,Umemura A,Mizuno M,Tanaka J,Okanoue T

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Better diagnosis of metastatic disease has been pursued by oncologists: however, many of the tumor markers have been still controversial. Our purpose was to estimate the usefulness of soluble E-selectin and its ligand sialyl Lewis A for more accurate diagnosis as a combined tumor marker for metastases in col...

journal_title：Journal of gastroenterology

authors： Ito K,Ye CL,Hibi K,Mitsuoka C,Kannagi R,Hidemura K,Ando H,Kasai Y,Akiyama S,Nakao A

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Studies on the risk of osteoporotic fractures related to the use of proton pump inhibitors (PPIs) have been inconsistent. One recent cohort study reported that there was an interaction between PPIs and bisphosphonates (BPs). Thus we performed a case-control study aimed at evaluating the risk of hip fractures...

journal_title：Journal of gastroenterology

authors： Lee J,Youn K,Choi NK,Lee JH,Kang D,Song HJ,Park BJ

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Acute liver failure is a potentially fatal disease of various etiologies for which liver transplantation is the only known curative treatment. Although the decision-making on transplantation is largely dependent on the severity of liver injury (based on predicting a fatal outcome), a statistical analysis to ...

journal_title：Journal of gastroenterology

authors： Mawatari S,Moriuchi A,Ohba F,Kawano T,Oda K,Takikawa Y,Takikawa H,Ido A,Tsubouchi H

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:We recently reported that the presence of a papillary adenocarcinoma (pap) component was an independent risk factor for lymphatic involvement in endoscopically resected early gastric cancer (EGC). This study aimed to investigate the potential association between the presence of a pap component in EGC and lym...

journal_title：Journal of gastroenterology

authors： Sekiguchi M,Kushima R,Oda I,Suzuki H,Taniguchi H,Sekine S,Fukagawa T,Katai H

更新日期：2015-04-01 00:00:00

abstract：:The relationship between sphincter of Oddi pressure and the morphological structure of the sphincter was studied in eight dogs prepared with a duodenal cannula. Sphincter of Oddi manometry was performed in awake animals in three directions, ventral, left dorsal, and right dorsal, using a catheter with three radial sid...

journal_title：Journal of gastroenterology

authors： Takeda T,Tohma H,Yoshida J,Naritomi G,Konomi H,Deng ZL,Kinukawa N,Tanaka M

更新日期：1998-12-01 00:00:00