Vector manometric study of the sphincter of Oddi in the dog: functional and morphological correlation.

Abstract:

:The relationship between sphincter of Oddi pressure and the morphological structure of the sphincter was studied in eight dogs prepared with a duodenal cannula. Sphincter of Oddi manometry was performed in awake animals in three directions, ventral, left dorsal, and right dorsal, using a catheter with three radial side holes for recording at one level. The pressure in the ventral direction (26.6+/-1.06 mmHg) (mean+/-SEM) was significantly lower than that in the left and right dorsal directions (30.6+/-1.42 and 31.2+/-1.23 mmHg, respectively). This functional manometric difference in the three directions correlated closely with the morphological structure of the sphincter of Oddi; the sum of the thickness of the sphincter of Oddi muscle and duodenal proper muscle was greater on the dorsal than on the ventral side. To our knowledge, this is the first report of axial asymmetry in sphincter of Oddi pressure.

journal_name

J Gastroenterol

authors

Takeda T,Tohma H,Yoshida J,Naritomi G,Konomi H,Deng ZL,Kinukawa N,Tanaka M

doi

10.1007/s005350050188

subject

Has Abstract

pub_date

1998-12-01 00:00:00

pages

860-3

issue

6

eissn

0944-1174

issn

1435-5922

journal_volume

33

pub_type

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