Abstract：
:Roundworms of the genus Baylisascaris are natural parasites primarily of wild carnivores, and they can occasionally cause infection in humans and animals. Infection results in visceral larva migrans and/or neural larva migrans, which can be severe or fatal in some animals. Recently, Baylisascaris nematodes isolated from kinkajous (Potos flavus) and previously referred to as Baylisascaris procyonis were renamed as Baylisascaris potosis; however, data regarding the pathogenicity of B. potosis towards animals and humans are lacking. In the present study, we experimentally infected squirrel monkeys (Saimiri sciureus) with B. potosis to determine the suitability of the monkey as a primate model. We used embryonated eggs of B. potosis at two different doses (10,000 eggs and 100,000 eggs) and examined the animals at 30 days post-infection. Histopathological examination showed the presence of B. potosis larvae and infiltration of inflammatory cells around a central B. potosis larvae in the brain, intestines, and liver. Nevertheless, the monkeys showed no clinical signs associated with infection. Parasitological examination revealed the presence of B. potosis larvae in the intestines, liver, lung, muscles, brain, kidney, and diaphragm. Our findings extend the range of species that are susceptible to B. potosis and provide evidence for the zoonotic potential of larva migrans in high dose infections.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Tokiwa T,Tsugo K,Nakamura S,Taira K,Une Ydoi
10.1016/j.parint.2015.03.003subject
Has Abstractpub_date
2015-10-01 00:00:00pages
284-7issue
5eissn
1383-5769issn
1873-0329pii
S1383-5769(15)00055-0journal_volume
64pub_type
杂志文章abstract：:The var genes encode a family of adhesion receptor proteins, Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), which profoundly influence malaria pathogenesis. Only a single var gene is transcribed and one PfEMP1 expressed per P.falciparum parasite. Here we present the in vivo transcript distribution of v...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.07.004
更新日期：2009-12-01 00:00:00
abstract：:The aim of the present study was to examine the frequency and genetic diversity of Blastocystis in cancer patients of a Medical Oncology Department in Aydın, Turkey. Patients' stool samples were examined between January 2013 and February 2014 by both microscopy and culture methods. Culture positive samples were subjec...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2016.02.010
更新日期：2016-12-01 00:00:00
abstract：:The outcome of Plasmodium yoelii 17XL (P.y17XL)-infected BALB/c and DBA/2 mice, ranging from death to spontaneous cure, depends largely on the establishment of effective Th1 and Th2 responses and a successful switch between Th1 and Th2 responses, as well as appropriate functioning of CD4(+)CD25(+)Foxp3(+)regulatory T ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2010.05.005
更新日期：2010-09-01 00:00:00
abstract：:Schistosomiasis is endemic in Indonesia in two isolated areas, Lindu valley and Napu valley, both located in the Province of Central Sulawesi. In 1940, a prevalence survey was initiated in Lake Lindu, which indicated a Schistosoma japonicum infection prevalence of 56% among the population of Anca, Tomado and Langko vi...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2008.04.008
更新日期：2008-09-01 00:00:00
abstract：:The pathogen Borrelia burgdorferi causes Lyme Borreliosis in human and animals world-wide. In Europe the pathogen is transmitted to the host by the vector Ixodes ricinus. The nymph is the primary instar for transmission to humans. We here study the infection rate of five Borrelia genospecies: B. burgdorferi sensu stri...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2007.07.004
更新日期：2008-03-01 00:00:00
abstract：:The third-stage (L3) larvae of Anisakis, which are the etiological agents of human anisakiasis, have been categorized morphologically into Anisakis Type I larvae and Anisakis Type II larvae. Genetic analysis has allowed easy identification of these larvae: Anisakis Type I larvae include the species Anisakis simplex se...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.02.008
更新日期：2011-06-01 00:00:00
abstract：:We report here the molecular characterization and possible function of a cysteine protease (termed HlCPL-A) identified in the midgut of the hard tick Haemaphysalis longicornis. HlCPL-A is a 333 amino acid protein belonging to the papain family of the cysteine protease. A construct encoding proHlCPL-A was expressed in ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.05.003
更新日期：2009-09-01 00:00:00
abstract：:The role of the virulent gene ROP18 polymorphisms is not known in human toxoplasmosis. A total of 320 clinical samples were analyzed. In samples positive for ROP18 gene, we determined by an allele specific PCR, if patients got the upstream insertion positive ROP18 sequence Toxoplasma strain (mouse avirulent strain) or...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2013.10.012
更新日期：2014-04-01 00:00:00
abstract：:Host-parasite interaction during infection with the liver fluke Opisthorchis viverrini plays an important role in opisthorchiasis-associated cholangiocarcinoma via nitric oxide (NO) production. Host cells induce nitric oxide synthase (NOS)-dependent DNA damage and secrete Ras-related C3 botulinum toxin substrate (Rac)...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.06.017
更新日期：2012-03-01 00:00:00
abstract：:The largest subunit of eukaryotic RNA polymerase II (RNA Pol II) of several members of Kinetoplastida order and other early diverging eukaryote contains a serine, tyrosine and proline-rich domain in the carboxyl-terminal instead of the typical heptapeptides repeats found in most eukaryotes. The lack of these repeats s...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(03)00009-6
更新日期：2003-09-01 00:00:00
abstract：:Chagas' disease is caused by the protozoan parasite Trypanosoma cruzi. About 8 million people throughout Latin America are infected causing approximately 10,000 deaths annually. Benznidazole, available as unique 100 mg tablets in many of the endemic countries, is currently the drug of choice for the specific treatment...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2012.09.001
更新日期：2013-02-01 00:00:00
abstract：:Pinworm parasites commonly infect laboratory mice with high prevalence even in well-managed animal colonies. Although often considered as irrelevant, these parasites if undetected may significantly interfere with the experimental settings and alter the interpretation of final results. There are a few reports documenti...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2005.10.005
更新日期：2006-06-01 00:00:00
abstract：:Toxoplasma gondii and Neospora caninum are two closely related protozoan parasites which can cause abortion and significant economic losses in sheep and goats. However, it is yet to know whether black-bone sheep and goats are infected with T. gondii and N. caninum in China. In the present investigation, the seropreval...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2019.102041
更新日期：2020-04-01 00:00:00
abstract：:The protozoan Trypanosoma cruzi is a parasite exposed to several environmental stressors inside its invertebrate and vertebrate hosts. Although stress conditions are involved in its differentiation processes, little information is available about the stress response proteins engaged in these activities. This work repo...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2017.10.009
更新日期：2018-04-01 00:00:00
abstract：:The salmon louse (Lepeophtheirus salmonis (Krøyer 1837)) is an ectoparasitic copepod which represents a major pathogen of wild and farmed salmonid fishes in the marine environment. In order to facilitate research on this ecologically and economically important parasite, a hatchery and culturing system permitting the c...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.08.009
更新日期：2009-12-01 00:00:00
abstract：:Granuloma modulation induced by antigen is an attractive model for vaccination studies of experimental schistosomiasis to test the effect of anti-pathology vaccine. We describe here an immunization procedure with culture derived macrophages-pulsed PIII, a known anionic antigen purified from S. mansoni adult worm, invo...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(02)00031-4
更新日期：2002-09-01 00:00:00
abstract：:We present evidence demonstrating that genes encoding enzymes essential for successful blood-feeding are differentially induced in the midgut of the hard tick Haemaphysalis longicornis. Three serine proteinase genes (HlSP, HlSP2 and HlSP3) isolated from H. longicornis midgut exhibit protein sequence similarity with ot...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2008.08.003
更新日期：2008-12-01 00:00:00
abstract：:Three hundred and forty-nine autopsy cases of schistosomiasis japonica were divided into two groups, based on the pathomorphology. Frequent regressive hepatic lesions such as active schistosomal lesion and destruction of limiting plates characterized the first group. The second group showed reparative hepatic lesions ...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2003.09.004
更新日期：2003-12-01 00:00:00
abstract：:This report describes a rare case of ophthalmic dirofilariasis in a 2-year-old boy with redness, irritation, pain and foreign body sensation in the right eye. Slit lamp examination demonstrated a thread-like whitish nematode in the anterior chamber of the right eye that twisted around itself. The nematode worm (35mm l...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2016.10.022
更新日期：2017-02-01 00:00:00
abstract：:We describe the cloning of a full length calpain-encoding cDNA constructed from two truncated cDNAs isolated from a cDNA library prepared with mRNA isolated from adult worms of the Philippine strain of Schistosoma japonicum. The cDNA sequence is 2.456 kb in length and predicts a protein of 758 residues with a molecula...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(99)00021-5
更新日期：2000-01-01 00:00:00
abstract：:Tick-borne protozoan and rickettsial diseases are a major threat to livestock in tropical and sub-tropical regions of Africa. In this study we investigated the presence and distribution of Theileria spp., Babesia ovis, Anaplasma ovis, Anaplasma phagocytophilum, Ehrlichia ruminantium and SFG Rickettsia in sheep and goa...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2017.11.002
更新日期：2018-04-01 00:00:00
abstract：:Plants rich in condensed tannins are an alternative to chemical anthelmintics to control gastrointestinal nematodes (GINs) in ruminants. Previous functional studies have shown that sainfoin extracts affect the two forms of infective larvae (L3), ensheathed and exsheathed. However, the mechanisms of action remain unkno...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2010.09.011
更新日期：2011-12-01 00:00:00
abstract：:The raccoon dog (Nyctereutes procyonoides viverrinus) is known to acquire canine heartworm (Dirofilaria immitis) infection. We surveyed the prevalence of heartworm infection in free-ranging raccoon dogs in the Nishi-Tama (Tokyo) and Kanagawa areas of Japan. A total of 75 raccoon dog carcasses, including 29 animals fro...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(00)00049-0
更新日期：2000-09-01 00:00:00
abstract：:Neospora caninum is an important cause of abortion in cattle worldwide. Dogs act as final hosts shedding oocysts in the environment. They can also harbour the extraintestinal stage of the parasite and this may be associated with a fairly rare neuromuscular condition. The sera of 781 dogs from the Algiers District were...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.08.008
更新日期：2009-12-01 00:00:00
abstract：:It has been reported that serine repeat antigen (SERA) binds directly to human erythrocyte membranes, inside-out vesicles and intact mouse erythrocytes. Similarly, mAbs specific against SERA are effective in blocking red blood cell (RBC) invasion by P. falciparum merozoites. Furthermore, the N-terminal recombinant SER...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(00)00040-4
更新日期：2000-08-01 00:00:00
abstract：:There has long been a debate as to the specific status of the cestode Taenia asiatica, with some people regarding it as a distinct species and some preferring to recognize it as a strain of Taenia saginata. The balance of current opinion seems to be that T. asiatica is a distinct species. In this study we performed an...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.10.007
更新日期：2010-03-01 00:00:00
abstract：:Brazilian sardine is emerging as a promising species in Aquaculture. This study describes for the first time a case of parasitic infestation by Amyloodinium in Brazilian sardines Sardinella brasiliensis obtained from natural spawning in captivity. The sardines kept in nurseries were naturally parasitized by the amylod...
journal_title：Parasitology international
pub_type：
doi：10.1016/j.parint.2020.102091
更新日期：2020-06-01 00:00:00
abstract：:Schistosoma mansoni enzymes play important roles in host-parasite interactions and are potential targets for immunological and/or pharmacological attack. The aim of this study was to comparatively assess the presence of hydrolytic activities (phosphatases, glycosidases, aminopeptidases) in soluble (SF) and membrane (M...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2016.09.015
更新日期：2017-02-01 00:00:00
abstract：:Gnathostomiasis is an emerging zoonosis in Mexico. However, for most endemic zones, the source of human infection has not been established. During 2000-2003, we investigated 2168 vertebrates (2047 fish, 31 amphibians, 4 reptiles, 19 birds and 67 mammals) from 39 localities distributed in nine states. We registered 7 v...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2004.10.001
更新日期：2005-03-01 00:00:00
abstract：:The salivary glands of Rhipicephalus sanguineus males at stages: unfed (control), at day seven post-attachment, and at days three and seven post-detachment from the host were examined using methods of enzymatic analysis and cell viability. At these stages of feeding, different staining patterns were observed in the ce...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2008.04.012
更新日期：2008-09-01 00:00:00
