Abstract：
:The role of the virulent gene ROP18 polymorphisms is not known in human toxoplasmosis. A total of 320 clinical samples were analyzed. In samples positive for ROP18 gene, we determined by an allele specific PCR, if patients got the upstream insertion positive ROP18 sequence Toxoplasma strain (mouse avirulent strain) or the upstream insertion negative ROP18 sequence Toxoplasma strain (mouse virulent strain). We designed an ELISA assay for antibodies against ROP18 derived peptides from the three major clonal lineages of Toxoplasma. 20 clinical samples were of quality for ROP18 allele analysis. In patients with ocular toxoplasmosis, a higher inflammatory reaction on eye was associated to a PCR negative result for the upstream region of ROP18. 23.3%, 33% and 16.6% of serums from individuals with ocular toxoplasmosis were positive for type I, type II and type III ROP18 derived peptides, respectively but this assay was affected by cross reaction. The absence of Toxoplasma ROP18 promoter insertion sequence in ocular toxoplasmosis was correlated with severe ocular inflammatory response. Determination of antibodies against ROP18 protein was not useful for serotyping in human toxoplasmosis.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Sánchez V,de-la-Torre A,Gómez-Marín JEdoi
10.1016/j.parint.2013.10.012subject
Has Abstractpub_date
2014-04-01 00:00:00pages
463-9issue
2eissn
1383-5769issn
1873-0329pii
S1383-5769(13)00172-4journal_volume
63pub_type
杂志文章abstract：:Plasmodial bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) is a validated antimalarial drug target. In this study, expression of the putative dhfr-ts of Plasmodium ovale rescued the DHFR chemical knockout and a TS null bacterial strain, demonstrating its DHFR and TS catalytic functions. PoDHFR-TS w...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.12.004
更新日期：2012-06-01 00:00:00
abstract：:Dientamoeba fragilis is an intestinal protozoan, an inhabitant of the human gastrointestinal tract, with a worldwide distribution. The reported prevalence of D. fragilis varies worldwide in different populations between 0.3% and 82.9%, and its role as a pathogen is still unclear. The parasite has been identified in th...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102227
更新日期：2021-02-01 00:00:00
abstract：:Fifty members of a novel class of antimicrobial compounds, 2-(4-R-phenoxymethyl)benzoic acid thioureides, were synthesized and characterized with respect to their activities against three parasites of human relevance, namely the protozoa Giardia lamblia and Toxoplasma gondii, and the larval (metacestode) stage of the ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2008.12.003
更新日期：2009-06-01 00:00:00
abstract：:A case of fatal infection caused by larval forms of Taenia martis in a ring-tailed lemur (Lemur catta) living in the Rome zoological garden is described. The animal, living in a semi-natural pen with other 15 conspecific individuals and being fed with fresh fruit and vegetables, yoghurt and eggs, was transported to th...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2014.05.008
更新日期：2014-10-01 00:00:00
abstract：:Two new species of bucephalids (Digenea: Bucephalidae) were found parasitizing freshwater fishes of Argentina. Prosorhynchoides cambapuntaensis sp. n. from Salminus maxillosus (Characidae) is characterised by the tegument covered with two kinds of spines, scale-like spines anteriorly and fine spines posteriorly; uteri...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2004.01.014
更新日期：2004-09-01 00:00:00
abstract：:The third-stage (L3) larvae of Anisakis, which are the etiological agents of human anisakiasis, have been categorized morphologically into Anisakis Type I larvae and Anisakis Type II larvae. Genetic analysis has allowed easy identification of these larvae: Anisakis Type I larvae include the species Anisakis simplex se...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.02.008
更新日期：2011-06-01 00:00:00
abstract：:A cat excreting Echinococcus multilocularis eggs was recently identified in Hokkaido, representing the first such observation in Japan. The cat was raised free-range and frequently ate rodents. Fecal egg examination revealed eggs of taeniids (EPG: 440) and Spirometra spp. (EPG: >1000). PCR targeting part of the mitoch...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2008.07.001
更新日期：2008-12-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(99)00021-5
更新日期：2000-01-01 00:00:00
abstract：:A strategy to engineer a strain of Culex mosquitoes refractory to filarial transmission is described. A requirement for success of the strategy is identification of a flight muscle-specific promoter that functions in the mosquito. A GFP marker gene under the control of the promoter region of the Drosophila melanogaste...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2004.04.002
更新日期：2004-12-01 00:00:00
abstract：:Lymphatic filariasis is endemic in India. Out of 128 million infected individuals worldwide, India accounts for 48 million cases [Manson's Tropical Diseases, 21st Ed. p 1488]. Filariasis can have protean manifestations, but Tropical pulmonary eosinophilia and chyluria are unusual manifestations reported mainly from So...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2007.03.002
更新日期：2007-09-01 00:00:00
abstract：:Owing to the need to combat the spread of acaricide-resistant ticks, the development of long-term biological control has become a hot topic for tick control. In this study, we investigated the pathogenicity of three Beauveria bassiana isolates on the engorged female Rhipicephalus (Boophilus) microplus ticks using diff...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2013.04.008
更新日期：2013-10-01 00:00:00
abstract：:Malaria is caused by five species of Plasmodium in humans. Microscopy is currently used for pathogen detection, requiring considerable training and technical expertise as the parasites are often difficult to differentiate morphologically. Rapid diagnostic tests are as reliable as microscopy and offer faster diagnoses ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2018.01.005
更新日期：2018-06-01 00:00:00
abstract：:The salmon louse (Lepeophtheirus salmonis (Krøyer 1837)) is an ectoparasitic copepod which represents a major pathogen of wild and farmed salmonid fishes in the marine environment. In order to facilitate research on this ecologically and economically important parasite, a hatchery and culturing system permitting the c...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.08.009
更新日期：2009-12-01 00:00:00
abstract：:Fasciolosis is an economically important disease of livestock caused by Fasciola hepatica, Fasciola gigantica, and aspermic Fasciola flukes. The aspermic Fasciola flukes have been discriminated morphologically from the two other species by the absence of sperm in their seminal vesicles. To date, the molecular discrimi...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.12.002
更新日期：2016-06-01 00:00:00
abstract：:Due to the increasing development of anthelmintic resistance in nematodes worldwide, it is important to search for anthelmintic compounds with new modes of action and also to investigate the possibility to combine compounds with possible synergistic effects. There might also be the chance to take advantage of the fact...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2013.05.006
更新日期：2013-12-01 00:00:00
abstract：:The liver fluke, Opisthorchis viverrini, causes serious public-health problems in the Lower Mekong Basin. This study aimed to clarify whether O. viverrini populations may be genetically divided into sub-specific taxa. We collected 6 populations of O. viverrini from different places in Cambodia, Lao PDR, and Thailand, ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2010.02.009
更新日期：2010-06-01 00:00:00
abstract：:The cercariae stages of Prosorhynchus crucibulum and Prosorhynchus aculeatus are morphologically indistinguishable. However, the differentiation of these two species is crucial to understand the transmission dynamics between these primary hosts (mussels) and the secondary hosts (fish). In this way, the objective of th...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.09.004
更新日期：2010-03-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102102
更新日期：2020-06-01 00:00:00
abstract：:Septin4 (Sept4) belongs to Septin family and may be involved in apoptosis, vesicle trafficking and other cell processes. In this study, we attempted to investigate the effect of Sept4 in hepatic fibrosis induced by Schistosoma japonicum. ICR mice infected with S. japonicum for 12weeks were treated with PBS, Ad-ctr and...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.07.002
更新日期：2015-12-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2005.11.053
更新日期：2006-01-01 00:00:00
abstract：:Schistosomiasis is endemic in Indonesia in two isolated areas, Lindu valley and Napu valley, both located in the Province of Central Sulawesi. In 1940, a prevalence survey was initiated in Lake Lindu, which indicated a Schistosoma japonicum infection prevalence of 56% among the population of Anca, Tomado and Langko vi...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2008.04.008
更新日期：2008-09-01 00:00:00
abstract：:Several Sarcocystis spp. have carnivores as definitive host and sarcocysts are common in muscles of herbivores (intermediate host). However, sarcocysts have been found in muscles of wild and domestic carnivores suggesting they are intermediate host for some Sarcocystis spp. Here, we report mature sarcocysts in the mus...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2017.01.021
更新日期：2017-06-01 00:00:00
abstract：:In this work, we characterized the gene encoding iron superoxide dismutase-A (FeSOD-A) in wild-type (WTS) and antimony-resistant (SbR) L. (Viannia) braziliensis and L. (Leishmania) infantum lines, which were selected in vitro. FeSOD-A transcript and protein expression were similar in all tested lines; however, specifi...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2014.11.001
更新日期：2015-04-01 00:00:00
abstract：:Alleviating morbidity due to lymphatic filariasis (LF)-especially in elderly patients who are rather ignorant-is presently the biggest challenge for the national filariasis campaign. We introduced two follow-up schemes and compared each other to address three key programmatic issues (1) locating patients, (2) educatin...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2017.11.005
更新日期：2018-04-01 00:00:00
abstract：:Based on specimens from the gill cavities of one Platichthys stellatus individual collected in the Sea of Japan, we investigated the taxonomic status of the enigmatic caligid genus Pseudolepeophtheirus and its type species, Pseudolepeophtheirus longicauda. In a maximum likelihood (ML) tree based on 18S rRNA gene seque...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102135
更新日期：2020-10-01 00:00:00
abstract：:Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) expressed on the surface of parasitized red blood cells (PRBCs) mediate adhesion of PRBCs to host vascular endothelial receptors and is considered responsible for pathogenesis of severe P. falciparum malaria. The present study was undertaken to measure cell...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2006.11.003
更新日期：2007-03-01 00:00:00
abstract：:This paper presents the morphological, histological, molecular and ultrastructural data on Myxobolus lomi sp. nov., a parasite of the gill filaments of Prochilodus lineatus from the Peixes River (48º06'38″W; 22º 49'53.1″S), São Paulo State, Brazil. From 20 P. lineatus specimens examined, 90.0% (n=18) were infected. Th...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2013.11.008
更新日期：2014-04-01 00:00:00
abstract：:Cystic echinococcosis is a zoonotic disease caused by the larval stage of the cestode Echinococcus granulosus. The drugs commonly used against cystic echinococcosis are benzimidazoles. Unfortunately, 20%-40% of cases do not respond favorably to such chemotherapy. Consequently, the search of new therapeutic alternative...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.06.005
更新日期：2015-10-01 00:00:00
abstract：:Dioctophymosis is the disease caused by the nematode Dioctophyme renale, normally found parasitizing the right kidney of dogs. The absence of symptoms is frequent in parasitized animals. The surgical procedures are commonly performed to treat this disease. This work describes a case involving a canine with renal and e...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102211
更新日期：2021-02-01 00:00:00
abstract：:We report here the molecular characterization and possible function of a cysteine protease (termed HlCPL-A) identified in the midgut of the hard tick Haemaphysalis longicornis. HlCPL-A is a 333 amino acid protein belonging to the papain family of the cysteine protease. A construct encoding proHlCPL-A was expressed in ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.05.003
更新日期：2009-09-01 00:00:00
