当前位置： SCI文献检索 > PARASITOLOGY INTERNATIONAL期刊下所有文献 > Ultrastructural changes in the third-stage, infective larvae of ruminant nematodes treated with sainfoin (Onobrychis viciifolia) extract.

Ultrastructural changes in the third-stage, infective larvae of ruminant nematodes treated with sainfoin (Onobrychis viciifolia) extract.

Abstract：

:Plants rich in condensed tannins are an alternative to chemical anthelmintics to control gastrointestinal nematodes (GINs) in ruminants. Previous functional studies have shown that sainfoin extracts affect the two forms of infective larvae (L3), ensheathed and exsheathed. However, the mechanisms of action remain unknown. The aim of this study was thus to compare ultrastructural changes in ensheathed and exsheathed L3 of two GIN species after in vitro contact with sainfoin extracts using transmission electron microscopy. The main changes identified were an alteration of the hypodermis, the presence of numerous vesicles in the cytoplasm and degeneration and/or death of muscular and intestinal cells. The changes suggested similar and nonspecies-specific lesions in the two nematode species. Comparison of the modifications found in the ensheathed vs. exsheathed L3s revealed different locations of the main cellular changes depending on the larval form. It is hypothesized that these spatial differences in lesions are mainly influenced by the presence of the sheath which favors contact between the active compounds and either the cuticle or the digestive tract. Overall, our observations suggest that the functional changes observed in the biology of GIN L3s after contact with sainfoin extracts are mediated through a direct mode of action, i.e. different interactions between the bioactive plant metabolites and the nematode structure depending on the route of contact.

journal_name

Parasitol Int

journal_title

Parasitology international

authors

Brunet S,Fourquaux I,Hoste H

doi

10.1016/j.parint.2010.09.011

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

419-24

issue

4

eissn

1383-5769

issn

1873-0329

pii

S1383-5769(11)00093-6

journal_volume

60

pub_type

杂志文章

相关文献

PARASITOLOGY INTERNATIONAL文献大全
  • Parasitological and biochemical parameters in Schistosoma mansoni-infected mice treated with methanol extract from the plants Chenopodium ambrosioides, Conyza dioscorides and Sesbania sesban.

    abstract：:This study aims to detect the antischistosomal properties of the plants' Chenopodium ambrosioides, Conyza dioscorides and Sesbania sesban methanol extract against Schistosoma mansoni in infected mice, including determination of total protein and albumin levels and the activities of alanine and aspartate transaminases ...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2011.06.016

    authors： Kamel EG,El-Emam MA,Mahmoud SS,Fouda FM,Bayaumy FE

    更新日期：2011-12-01 00:00:00

  • Intestinally implanted Nippostrongylus brasiliensis adult worms decrease serum paraoxonase-1 activity in rats.

    abstract：:We have previously reported a significant decrease in serum PON1 activity after Nippostrongylus brasiliensis infection in Wistar rats in association with the inflammatory response mounted against the parasite in the migratory phase of infection. However, the roles of intestinal phase and the associated oxidative stres...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2009.03.001

    authors： Farid AS,Shimohira T,Kobayashi I,Sawada J,Horii Y

    更新日期：2009-06-01 00:00:00

  • Genetic characterization of Giardia duodenalis by sequence analysis in humans and animals in Pemba Island, Tanzania.

    abstract：:Giardia duodenalis represents one of the most widespread human enteric parasites: about 200million people in Asia, Africa and Latin America are infected. Giardia exerts a deep impact on public health because of high prevalence and possible effects on growth and cognitive functions in infected children. The major aim o...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2013.11.004

    authors： Di Cristanziano V,Santoro M,Parisi F,Albonico M,Shaali MA,Di Cave D,Berrilli F

    更新日期：2014-04-01 00:00:00

  • Case report: Intestinal perforation and secondary peritonitis due to Acanthocephala infection in a black-bellied pangolin (Phataginus tetradactyla).

    abstract：:A case of Acanthocephala infection in a 5-year-old female rehabilitated and released black-bellied pangolin (Phataginus tetradactyla), which was part of a post-release monitoring program of a pangolin research operation in the Central African Republic, is described. This represents the first report of Acanthocephala i...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2020.102182

    authors： Sist B,Basso W,Hemphill A,Cassidy T,Cassidy R,Gudehus M

    更新日期：2021-02-01 00:00:00

  • Where are the tapeworms?

    abstract：:This review analyzes the literature in search of an answer to the fact that, in general, tapeworms are very difficult to recover. The results and comments of the authors that have searched for Taenia solium, either to define the local prevalence in different countries of Latin America, to assess the efficacy of cestoc...

    journal_title：Parasitology international

    pub_type： 杂志文章,评审

    doi：10.1016/j.parint.2005.11.018

    authors： Flisser A

    更新日期：2006-01-01 00:00:00

  • Ribosomal protein P2 localizes to the parasite zoite-surface and is a target for invasion inhibitory antibodies in Toxoplasma gondii and Plasmodium falciparum.

    abstract：:In the malarial parasite Plasmodium falciparum, the conserved ribosomal stalk protein P2 (PfP2) exhibits extra-ribosomal stage-specific oligomerization and trafficking to the host red cell membrane. Antibodies directed against PfP2 arrested cell division. We sought to examine whether P2 from a closely related Apicompl...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2014.08.006

    authors： Sudarsan R,Chopra RK,Khan MA,Sharma S

    更新日期：2015-02-01 00:00:00

  • Chyluria with proteinuria or filarial nephropathy? An enigma.

    abstract：:Lymphatic filariasis is endemic in India. Out of 128 million infected individuals worldwide, India accounts for 48 million cases [Manson's Tropical Diseases, 21st Ed. p 1488]. Filariasis can have protean manifestations, but Tropical pulmonary eosinophilia and chyluria are unusual manifestations reported mainly from So...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2007.03.002

    authors： Gulati S,Gupta N,Singh NP,Batra S,Garg S,Beniwal P,Kumar S

    更新日期：2007-09-01 00:00:00

  • Seroprevalence of Toxoplasma gondii infection in cattle, horses, pigs and chickens in Japan.

    abstract：:The presence of antibodies to Toxoplasma gondii in livestock and poultry was investigated by latex agglutination tests; samples that agglutinated at dilutions of 1:64 or higher were regarded as positive. Sera were collected from fattening beef cattle (102 Japanese black, 105 crossbreeds and 114 castrated Holstein), cu...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2014.04.003

    authors： Matsuo K,Kamai R,Uetsu H,Goto H,Takashima Y,Nagamune K

    更新日期：2014-08-01 00:00:00

  • Seroprevalence and risk factors associated with Toxoplasma gondii in domestic pigs from Spain.

    abstract：:Serum samples from 2970 (1400 sows, 1570 fattening) pigs, from 100 farms in the 10 main swine production regions in Spain were tested for antibodies against T. gondii by the modified agglutination test (MAT). Antibodies to T. gondii (MAT 1:25 or higher) were detected in 492 pigs (16.6%, 9.7% in fattening pigs and 24.2...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2010.06.001

    authors： García-Bocanegra I,Simon-Grifé M,Dubey JP,Casal J,Martín GE,Cabezón O,Perea A,Almería S

    更新日期：2010-09-01 00:00:00

  • A mathematical model for the transmission of Plasmodium vivax malaria.

    abstract：:We have proposed a mathematical model for the transmission of Plasmodium vivax malaria quantitatively, which is adjusted to the infected region, Guadalcanal, in the Solomon Islands. The simulation of a transmission model will be instrumental in planning the malaria control strategy. A characteristic of the life cycle ...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/s1383-5769(02)00084-3

    authors： Ishikawa H,Ishii A,Nagai N,Ohmae H,Harada M,Suguri S,Leafasia J

    更新日期：2003-03-01 00:00:00

  • Analysis of phosphorylated proteins and inhibition of kinase activity during Giardia intestinalis excystation.

    abstract：:The parasite Giardia intestinalis undergoes a differentiation process that allows it to infect its mammal host. That process is excystation. We examined the importance of protein phosphorylation during the passage from cyst to trophozoite. Cysts obtained from patients with giardiasis were excysted in vitro and the sol...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2009.10.005

    authors： Alvarado ME,Wasserman M

    更新日期：2010-03-01 00:00:00

  • Molecular characterization and phylogenetic analysis of Fasciola gigantica from Nigeria.

    abstract：:Fasciola gigantica is considered the major pathogen causing fasciolosis in Africa; however, molecular characterization of this fluke has not been adequately elucidated. It is important to scientifically elucidate the dispersal history of F. gigantica by analyzing its genetic diversity. Fasciola flukes from Nigeria wer...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2016.10.010

    authors： Ichikawa-Seki M,Tokashiki M,Opara MN,Iroh G,Hayashi K,Kumar UM,Itagaki T

    更新日期：2017-02-01 00:00:00

  • Characterization of thioredoxin glutathione reductase in Schiotosoma japonicum.

    abstract：:Schistosomiasis is one of the most prevalent and serious parasitic diseases in the world and remains an important public health problem in China. Screening and discovery of an effective vaccine candidate or new drug target is crucial for the control of this disease. In this study, we cloned a cDNA encoding Schistosoma...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2012.03.005

    authors： Han Y,Zhang M,Hong Y,Zhu Z,Li D,Li X,Fu Z,Lin J

    更新日期：2012-09-01 00:00:00

  • Complete Mitochondrial genome of an equine intestinal parasite, Triodontophorus brevicauda (Chromadorea: Strongylidae): the first characterization within the genus.

    abstract：:The complete mitochondrial (mt) genome sequence of Triodontophorus brevicauda, an intestinal equine nematode parasite was determined for the first time. The circular T. brevicauda mt genome is 14,305 bp in length and contains 36 genes, of which 12 code for protein, 22 for transfer RNA, and two for ribosomal RNA, and l...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2015.06.006

    authors： Duan H,Gao JF,Hou MR,Zhang Y,Liu ZX,Gao DZ,Guo DH,Yue DM,Su X,Fu X,Wang CR

    更新日期：2015-10-01 00:00:00

  • Supplementary studies on Henneguya guanduensis (Cnidaria: Myxosporea) infecting gills and intestine of Hoplosternum littorale in Brazil: Ultrastructural and molecular data.

    abstract：:Henneguya guanduensis was originally described as a gill parasite of the Hoplosternum litoralle, a siluriform fish belonging to the Callichthyidae family. A study was undertaken with 58 specimens of H. litoralle taken from Batalha River in the state of São Paulo. The fish were collected and examined searching for lesi...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2019.01.009

    authors： Vieira DHMD,Pelegrini LS,Abdallah VD,de Azevedo RK

    更新日期：2019-06-01 00:00:00

  • Hyperapolytic species of Acanthobothrium (Cestoda: Onchoproteocephalidea) from batoids off Argentina.

    abstract：:Two hyperapolytic species of Acanthobothrium Blanchard, 1848 have been collected from Discopyge tschudii Heckel, 1846 and Zapteryx brevirostris (Müller et Henle) along the coast of Argentina. Acanthobothrium stefaniae sp. n. from D. tschudii is a category one species (i.e., it is less than 15 mm in total length, posse...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2018.04.001

    authors： Franzese S,Ivanov VA

    更新日期：2018-08-01 00:00:00

  • Monophyly of Opisthorchis viverrini populations in the lower Mekong Basin, using mitochondrial DNA nad1 gene as the marker.

    abstract：:The liver fluke, Opisthorchis viverrini, causes serious public-health problems in the Lower Mekong Basin. This study aimed to clarify whether O. viverrini populations may be genetically divided into sub-specific taxa. We collected 6 populations of O. viverrini from different places in Cambodia, Lao PDR, and Thailand, ...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2010.02.009

    authors： Thaenkham U,Nuamtanong S,Sa-nguankiat S,Yoonuan T,Touch S,Manivong K,Vonghachack Y,Sato M,Waikagul J

    更新日期：2010-06-01 00:00:00

  • Responses of Squalius cephalus intestinal mucous cells to Pomphorhynchus laevis.

    abstract：:Intestinal mucous cell numbers and their glycoconjugate composition were investigated by histochemical methods in uninfected chub, Squalius cephalus, and in conspecifics naturally parasitised with the acanthocephalan Pomphorhynchus laevis. A sub-population of 42 chub from the River Tiber (Perugia, Italy) were sampled ...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2014.11.018

    authors： Bosi G,Sayyaf Dezfuli B

    更新日期：2015-04-01 00:00:00

  • Activity of several kinds of drugs against Neospora caninum.

    abstract：:Neosporosis caused by Neospora caninum is a serious disease in cattle and dogs worldwide. It is the major cause of abortion and neonatal mortality in cattle. In this study, we evaluated the anti-N. caninum activity of Chinese medicine extracts (curcumin, artemether), herbicides (atrazine, glyphosate), anticoccidiosis ...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2015.08.002

    authors： Qian W,Wang H,Shan D,Li B,Liu J,Liu Q

    更新日期：2015-12-01 00:00:00

  • Peroxiredoxins in malaria parasites: parasitologic aspects.

    abstract：:Malaria is one of the most debilitating and life threatening diseases in tropical regions of the world. Over 500 million clinical cases occur, and 2-3 million people die of the disease each year. Because Plasmodium lacks genuine glutathione peroxidase and catalase, the two major antioxidant enzymes in the eukaryotic c...

    journal_title：Parasitology international

    pub_type： 杂志文章,评审

    doi：10.1016/j.parint.2007.08.001

    authors： Kawazu S,Komaki-Yasuda K,Oku H,Kano S

    更新日期：2008-03-01 00:00:00

  • Establishment of an in vitro transgene expression system in epimastigotes of Trypanosoma congolense.

    abstract：:Trypanosoma congolense epimastigote forms (EMFs) adhere to the tsetse fly proboscis, proliferate, and differentiate into animal-infective metacyclic forms (MCFs). This differentiation step, called metacyclogenesis, is indispensable for the cyclical transmission of the parasite. Although an in vitro metacyclogenesis cu...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2008.12.001

    authors： Sakurai T,Tanaka M,Kawazu S,Inoue N

    更新日期：2009-03-01 00:00:00

  • Genetic diversity and phylogeography of Corynosoma australe Johnston, 1937 (Acanthocephala: Polymorphidae), an endoparasite of otariids from the Americas in the northern and southern hemispheres.

    abstract：:Adult specimens of Corynosoma australe Johnston, 1937 were recorded from the intestines of California sea lions, Zalophus californianus (Lesson), from Baja California Peninsula, Mexico, whereas larval forms were collected from two fish species on the Argentinian coast. Adult specimens of C. australe were morphological...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2020.102205

    authors： García-Varela M,Masper A,Crespo EA,Hernández-Orts JS

    更新日期：2021-02-01 00:00:00

  • Thioureides of 2-(phenoxymethyl)benzoic acid 4-R substituted: a novel class of anti-parasitic compounds.

    abstract：:Fifty members of a novel class of antimicrobial compounds, 2-(4-R-phenoxymethyl)benzoic acid thioureides, were synthesized and characterized with respect to their activities against three parasites of human relevance, namely the protozoa Giardia lamblia and Toxoplasma gondii, and the larval (metacestode) stage of the ...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2008.12.003

    authors： Müller J,Limban C,Stadelmann B,Missir AV,Chirita IC,Chifiriuc MC,Nitulescu GM,Hemphill A

    更新日期：2009-06-01 00:00:00

  • Expression profiles of peroxiredoxins in liver stage of the rodent malaria parasite Plasmodium berghei.

    abstract：:mRNA and protein expression profiles for three peroxiredoxins (TPx-1, TPx-2 and 1-Cys Prx) of liver stage Plasmodium berghei were examined through quantitative reverse transcription-PCR (RT-PCR) and indirect immunofluorescence microscopy assay (IFA). RT-PCR experiments revealed that mRNA expression for the TPx-1 was d...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2012.11.007

    authors： Usui M,Masuda-Suganuma H,Fukumoto S,Angeles JM,Inoue N,Kawazu S

    更新日期：2013-06-01 00:00:00

  • Hemoglobinase activity of a cysteine protease from the ixodid tick Haemaphysalis longicornis.

    abstract：:We report here the molecular characterization and possible function of a cysteine protease (termed HlCPL-A) identified in the midgut of the hard tick Haemaphysalis longicornis. HlCPL-A is a 333 amino acid protein belonging to the papain family of the cysteine protease. A construct encoding proHlCPL-A was expressed in ...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2009.05.003

    authors： Yamaji K,Tsuji N,Miyoshi T,Islam MK,Hatta T,Alim MA,Anisuzzaman,Takenaka A,Fujisaki K

    更新日期：2009-09-01 00:00:00

  • Mitochondrial DNA divergence in populations of the tapeworm Diphyllobothrium nihonkaiense and its phylogenetic relationship with Diphyllobothrium klebanovskii.

    abstract：:Diphyllobothrium nihonkaiense [Y. Yamane, H. Kamo, G. Bylund, J.P. Wilkgren. Diphyllobothrium nihonkaiense sp. nov (Cestoda: Diphyllobothriidae)- revised identification of Japanese broad tapeworm. Shimane J Med Sci 1986;10:29-48.] and Diphyllobothrium klebanovskii [I.V. Muratov, P.S. Posokhov. Causative agent of human...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2008.09.001

    authors： Arizono N,Shedko M,Yamada M,Uchikawa R,Tegoshi T,Takeda K,Hashimoto K

    更新日期：2009-03-01 00:00:00

  • Entamoeba histolytica: Overexpression of the gal/galnac lectin, ehcp2 and ehcp5 genes in an in vivo model of amebiasis.

    abstract：:The parasite Entamoeba histolytica causes intestinal amebiasis and amebic liver abscess as its main extraintestinal manifestation. To study the in vivo events related to inflammation and the interactions between hosts and parasites during amebiasis, we designed a novel model of host-parasite interactions using cellulo...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2016.08.009

    authors： Sánchez V,Serrano-Luna J,Ramírez-Moreno E,Tsutsumi V,Shibayama M

    更新日期：2016-12-01 00:00:00

  • In vivo imaging of trypanosomes for a better assessment of host-parasite relationships and drug efficacy.

    abstract：:The advances in microscopy combined to the invaluable progress carried by the utilization of molecular, immunological or immunochemical markers and the implementation of more powerful imaging technologies have yielded great improvements to the knowledge of the interaction between microorganisms and their hosts, notabl...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2013.07.011

    authors： Goyard S,Dutra PL,Deolindo P,Autheman D,D'Archivio S,Minoprio P

    更新日期：2014-02-01 00:00:00

  • The liver fluke Opisthorchis viverrini expresses nitric oxide synthase but not gelatinases.

    abstract：:Host-parasite interaction during infection with the liver fluke Opisthorchis viverrini plays an important role in opisthorchiasis-associated cholangiocarcinoma via nitric oxide (NO) production. Host cells induce nitric oxide synthase (NOS)-dependent DNA damage and secrete Ras-related C3 botulinum toxin substrate (Rac)...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2011.06.017

    authors： Prakobwong S,Pinlaor P,Charoensuk L,Khoontawad J,Yongvanit P,Hiraku Y,Pinlaor S

    更新日期：2012-03-01 00:00:00

  • Fatal infection with Taenia martis metacestodes in a ring-tailed lemur (Lemur catta) living in an Italian zoological garden.

    abstract：:A case of fatal infection caused by larval forms of Taenia martis in a ring-tailed lemur (Lemur catta) living in the Rome zoological garden is described. The animal, living in a semi-natural pen with other 15 conspecific individuals and being fed with fresh fruit and vegetables, yoghurt and eggs, was transported to th...

    journal_title：Parasitology international

    pub_type： 杂志文章

    doi：10.1016/j.parint.2014.05.008

    authors： De Liberato C,Berrilli F,Meoli R,Friedrich KG,Di Cerbo P,Cocumelli C,Eleni C

    更新日期：2014-10-01 00:00:00