Abstract：
:The parasite Giardia intestinalis undergoes a differentiation process that allows it to infect its mammal host. That process is excystation. We examined the importance of protein phosphorylation during the passage from cyst to trophozoite. Cysts obtained from patients with giardiasis were excysted in vitro and the soluble cytoplasmic proteins were analyzed during the three phases of the process, using a specific staining for phosphoproteins. We found two phosphorylated proteins and identified them with MALDI-TOF as 14-3-3 and Hsp70. Modifications were detected in both proteins, which could indicate a role in differentiation of the parasite. In addition, the inhibition of serine-threonine kinases during excystation specifically affected the cytokinesis of the excyzoite, thus inhibiting the completion of trophozoite formation.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Alvarado ME,Wasserman Mdoi
10.1016/j.parint.2009.10.005subject
Has Abstractpub_date
2010-03-01 00:00:00pages
54-61issue
1eissn
1383-5769issn
1873-0329pii
S1383-5769(09)00131-7journal_volume
59pub_type
杂志文章abstract：:Gyrodactylus medaka n. sp. (Monogenea: Gyrodactylidae) is described from the skin, fins, and gills of medaka Oryzias latipes (Beloniformes: Adrianichthyidae) from Japan. This new species was collected from wild medaka in Hiroshima, Aichi, Saga, and Kumamoto prefectures, and laboratory-reared medaka in Chiba and Aichi ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2018.06.010
更新日期：2018-10-01 00:00:00
abstract：:Miamiensis avidus causes scuticociliatosis in cultured olive flounders (Paralichthys olivaceus), leading to economic losses in aquaculture in Korea. Quantitative evaluation of the viability of M. avidus is important to develop an effective vaccine or chemotherapeutic agent against it. We used a colorimetric assay base...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102093
更新日期：2020-06-01 00:00:00
abstract：:Dioctophymosis is the disease caused by the nematode Dioctophyme renale, normally found parasitizing the right kidney of dogs. The absence of symptoms is frequent in parasitized animals. The surgical procedures are commonly performed to treat this disease. This work describes a case involving a canine with renal and e...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102211
更新日期：2021-02-01 00:00:00
abstract：:Alternative strategies are being designed to identify candidates among drugs already available on the market that could be used in combination to improve the efficacy of Chagas disease treatment. This work evaluates the effect of the association of clomipramine (CLO) with benznidazole (BZN) for the treatment of experi...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2013.02.004
更新日期：2013-06-01 00:00:00
abstract：:Individuals living in malaria endemic areas become clinically immune after multiple re-infections over time and remain infected without apparent symptoms. However, it is unclear why a long period is required to gain clinical immunity to malaria, and how such immunity is maintained. Although malaria infection is report...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2018.01.001
更新日期：2018-06-01 00:00:00
abstract：:European liver fluke (Opisthorchis felineus) and Asian liver fluke (Opisthorchis viverrini) are similar in morphology but comparative pathology of the infections has not been described. We therefore did comparative histopathology of both parasites in an experimental animal model. The study was conducted in 3 groups of...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.08.005
更新日期：2012-03-01 00:00:00
abstract：:Brazilian sardine is emerging as a promising species in Aquaculture. This study describes for the first time a case of parasitic infestation by Amyloodinium in Brazilian sardines Sardinella brasiliensis obtained from natural spawning in captivity. The sardines kept in nurseries were naturally parasitized by the amylod...
journal_title：Parasitology international
pub_type：
doi：10.1016/j.parint.2020.102091
更新日期：2020-06-01 00:00:00
abstract：:Immunodeficient mice were studied to determine their suitability as models in investigating the role of Taenia taeniaeformis larval products in the development of gastric hyperplasia. Recombinant active gene 2 (RAG2)-deficient and severe combined immune-deficient (SCID) mice were studied as candidate animal models. RA...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(01)00108-8
更新日期：2002-03-01 00:00:00
abstract：:Except for imported cases, we have had no new Schistosoma japonicum infection in Japan since 1977. But there are still two habitats of the intermediate snail host: Oncomelania nosophora in the previous endemic areas of Kofu Basin and Obitsu. O. nosophora from Kofu Basin and Obitsu are susceptible to Chinese and Philip...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/s1383-5769(03)00058-8
更新日期：2003-12-01 00:00:00
abstract：:This report describes a rare case of ophthalmic dirofilariasis in a 2-year-old boy with redness, irritation, pain and foreign body sensation in the right eye. Slit lamp examination demonstrated a thread-like whitish nematode in the anterior chamber of the right eye that twisted around itself. The nematode worm (35mm l...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2016.10.022
更新日期：2017-02-01 00:00:00
abstract：:Autophagy is a homeostatic process promoting cell survival in periods of stress. The induction of the autophagic machinery has also been implicated in both innate and adaptive immunity. Leishmania donovani, which is the causative pathogen of visceral leishmaniasis, is an intracellular parasite that invades and multipl...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.07.002
更新日期：2009-12-01 00:00:00
abstract：:Acanthocephalans of the order Echinorhynchida are one of the most diverse groups in their phylum, with approximately 470 species classified into 11 families that largely consist of parasites of freshwater, brackish and marine fishes and, sporadically, reptiles and amphibians distributed worldwide. Previous phylogenies...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102264
更新日期：2020-12-07 00:00:00
abstract：:Schistosomiasis is one of the most prevalent and serious parasitic diseases in the world and remains an important public health problem in China. Screening and discovery of an effective vaccine candidate or new drug target is crucial for the control of this disease. In this study, we cloned a cDNA encoding Schistosoma...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2012.03.005
更新日期：2012-09-01 00:00:00
abstract：:This paper presents the morphological, histological, molecular and ultrastructural data on Myxobolus lomi sp. nov., a parasite of the gill filaments of Prochilodus lineatus from the Peixes River (48º06'38″W; 22º 49'53.1″S), São Paulo State, Brazil. From 20 P. lineatus specimens examined, 90.0% (n=18) were infected. Th...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2013.11.008
更新日期：2014-04-01 00:00:00
abstract：:Alveolar echinococcosis (AE) of the liver caused by the metacestode of the fox tapeworm Echinococcus multilocularis is characterized by a multivesicular structure surrounded by an extensive fibro-inflammatory host reaction. The lesions behave like a slow-growing liver cancer, without sharp limits between the parasitic...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2005.11.053
更新日期：2006-01-01 00:00:00
abstract：:The presence of iron in the extracellular medium is essential for both in vivo and in vitro survival of pathogenic microorganisms, including Trichomonas vaginalis and Tritrichomonas foetus. In these parasites, iron is directly involved in the proliferation, protein expression and activation of critical enzymes. The pu...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2006.08.002
更新日期：2006-12-01 00:00:00
abstract：:The raccoon dog (Nyctereutes procyonoides viverrinus) is known to acquire canine heartworm (Dirofilaria immitis) infection. We surveyed the prevalence of heartworm infection in free-ranging raccoon dogs in the Nishi-Tama (Tokyo) and Kanagawa areas of Japan. A total of 75 raccoon dog carcasses, including 29 animals fro...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(00)00049-0
更新日期：2000-09-01 00:00:00
abstract：:Malaria is one of the most debilitating and life threatening diseases in tropical regions of the world. Over 500 million clinical cases occur, and 2-3 million people die of the disease each year. Because Plasmodium lacks genuine glutathione peroxidase and catalase, the two major antioxidant enzymes in the eukaryotic c...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2007.08.001
更新日期：2008-03-01 00:00:00
abstract：:Schistosoma mansoni enzymes play important roles in host-parasite interactions and are potential targets for immunological and/or pharmacological attack. The aim of this study was to comparatively assess the presence of hydrolytic activities (phosphatases, glycosidases, aminopeptidases) in soluble (SF) and membrane (M...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2016.09.015
更新日期：2017-02-01 00:00:00
abstract：:Marine fishes represent the important components of the diet in the coastal areas of China and they are also natural hosts of various parasites. However, to date, little is known about the occurrence of ascaridoid parasites in the frequently consumed marine fishes in China. In order to determine the presence of ascari...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.11.002
更新日期：2016-04-01 00:00:00
abstract：:Septin4 (Sept4) belongs to Septin family and may be involved in apoptosis, vesicle trafficking and other cell processes. In this study, we attempted to investigate the effect of Sept4 in hepatic fibrosis induced by Schistosoma japonicum. ICR mice infected with S. japonicum for 12weeks were treated with PBS, Ad-ctr and...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.07.002
更新日期：2015-12-01 00:00:00
abstract：:A case of Acanthocephala infection in a 5-year-old female rehabilitated and released black-bellied pangolin (Phataginus tetradactyla), which was part of a post-release monitoring program of a pangolin research operation in the Central African Republic, is described. This represents the first report of Acanthocephala i...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102182
更新日期：2021-02-01 00:00:00
abstract：:Plants rich in condensed tannins are an alternative to chemical anthelmintics to control gastrointestinal nematodes (GINs) in ruminants. Previous functional studies have shown that sainfoin extracts affect the two forms of infective larvae (L3), ensheathed and exsheathed. However, the mechanisms of action remain unkno...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2010.09.011
更新日期：2011-12-01 00:00:00
abstract：:"Below is an essay by Prof. Tanabe originally written in Japanese. It gives an insight to Prof. Tanabe's inquiring mind and his approach to science. He also seek, as always, to inspire and nudge the young to scientific discovery". ...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2014.11.010
更新日期：2015-06-01 00:00:00
abstract：:Control of morbidity associated with schistosomiasis via chemotherapy largely relies on the drug praziquantel. Repeated therapy with praziquantel has created concerns about the possible selection of resistant worms and necessitated the search for novel drugs to treat schistosomiasis. Here, a murine model was infected ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2018.03.006
更新日期：2018-08-01 00:00:00
abstract：:Fasciola gigantica is considered the major pathogen causing fasciolosis in Africa; however, molecular characterization of this fluke has not been adequately elucidated. It is important to scientifically elucidate the dispersal history of F. gigantica by analyzing its genetic diversity. Fasciola flukes from Nigeria wer...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2016.10.010
更新日期：2017-02-01 00:00:00
abstract：:Larval infection with Echinococcus multilocularis starts with the intrahepatic postoncospheral development of a metacestode that-at its mature stage-consists of an inner germinal and an outer laminated layer (GL & LL). In certain cases, an appropriate host immune response may inhibit parasite proliferation. Several li...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2005.11.006
更新日期：2006-01-01 00:00:00
abstract：:In the malarial parasite Plasmodium falciparum, the conserved ribosomal stalk protein P2 (PfP2) exhibits extra-ribosomal stage-specific oligomerization and trafficking to the host red cell membrane. Antibodies directed against PfP2 arrested cell division. We sought to examine whether P2 from a closely related Apicompl...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2014.08.006
更新日期：2015-02-01 00:00:00
abstract：:Three hundred and forty-nine autopsy cases of schistosomiasis japonica were divided into two groups, based on the pathomorphology. Frequent regressive hepatic lesions such as active schistosomal lesion and destruction of limiting plates characterized the first group. The second group showed reparative hepatic lesions ...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2003.09.004
更新日期：2003-12-01 00:00:00
abstract：:Fifty members of a novel class of antimicrobial compounds, 2-(4-R-phenoxymethyl)benzoic acid thioureides, were synthesized and characterized with respect to their activities against three parasites of human relevance, namely the protozoa Giardia lamblia and Toxoplasma gondii, and the larval (metacestode) stage of the ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2008.12.003
更新日期：2009-06-01 00:00:00
