Abstract:
:European liver fluke (Opisthorchis felineus) and Asian liver fluke (Opisthorchis viverrini) are similar in morphology but comparative pathology of the infections has not been described. We therefore did comparative histopathology of both parasites in an experimental animal model. The study was conducted in 3 groups of 105 Syrian golden hamsters; the first and second groups fed with 50 metacercariae of O. felineus (OF) or O. viverrini (OV) and the last group was uninfected controls. Five hamsters in each group were euthanized on weeks 1, 2, 4, 8, 12 and 24 post-infection. The liver tissue was fixed and processed for routine histopathology and immunohistochemistry for proliferation markers (BrdU or PCNA). Overall, the liver histopathology of O. felineus and O. viverrini infection was generally similar. However, various histopathogical features including intense inflammation, fibrosis, biliary and goblet cell hyperplasia and dysplasia occurred earlier in the OF group. In addition, the existence of precancerous lesions such as cholangiofibrosis in a long-term infection was observed only in this group. O. felineus is larger in size than O. viverrini which, together with its excreted and secreted antigens, likely is crucial in the induction of liver fluke induced disease. The differences in nature and timing of the histopathological profile indicate that opisthorchiasis caused by the European liver fluke O. felineus is more pathogenic than its Asian relative O. viverrini.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Lvova MN,Tangkawattana S,Balthaisong S,Katokhin AV,Mordvinov VA,Sripa Bdoi
10.1016/j.parint.2011.08.005subject
Has Abstractpub_date
2012-03-01 00:00:00pages
167-72issue
1eissn
1383-5769issn
1873-0329pii
S1383-5769(11)00124-3journal_volume
61pub_type
杂志文章abstract::Toxoplasma gondii is a protozoan parasite that infects a wide variety of warm-blooded animals and humans, in which it causes opportunistic disease. As an obligate intracellular parasite, T. gondii must invade a host cell to survive and replicate during infection. Recent studies suggest that T. gondii secretes a variet...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/s1383-5769(98)00042-7
更新日期:1999-03-01 00:00:00
abstract::Haintestinum amplum n. g., n. sp. is described from the scrawled cowfish, Acanthostracion quadricornis, collected in the Eastern Gulf of Mexico off Florida, USA. The new species is relatively large and shares characters of the Apocreadiidae and Megaperidae but conforms to the diagnosis of neither. It belongs in a new ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2013.11.007
更新日期:2014-04-01 00:00:00
abstract::Diphyllobothrium hottai Yazaki, Fukumoto & Abe, 1988 was described based on the morphology of adult worms recovered from golden hamsters that had been experimentally infected with plerocercoids obtained from Japanese surf smelts (Hypomesus pretiosus japonicus) and olive rainbow smelts (Osmerus eperlanus mordax). Altho...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2016.06.011
更新日期:2016-10-01 00:00:00
abstract::In murine leishmaniasis, the induction of the T-helper type 1 (Th1) response contributes to infection resistance, whereas the establishment of the Th2 response makes the mice susceptible to infection. Interleukin-12 (IL-12) plays a pivotal role in the diversification of immune responses to the Th1 type. In this study,...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/s1383-5769(01)00070-8
更新日期:2001-07-01 00:00:00
abstract::Larval infection with Echinococcus multilocularis starts with the intrahepatic postoncospheral development of a metacestode that-at its mature stage-consists of an inner germinal and an outer laminated layer (GL & LL). In certain cases, an appropriate host immune response may inhibit parasite proliferation. Several li...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2005.11.006
更新日期:2006-01-01 00:00:00
abstract::Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) expressed on the surface of parasitized red blood cells (PRBCs) mediate adhesion of PRBCs to host vascular endothelial receptors and is considered responsible for pathogenesis of severe P. falciparum malaria. The present study was undertaken to measure cell...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2006.11.003
更新日期:2007-03-01 00:00:00
abstract::This study was conducted both to assess the prevalence of parasitic infections in two neighboring villages of Manisa province in Turkey, with different socioeconomic levels and investigate the influences of some individual and environmental factors on these infections. A total of 100 school children were enrolled and ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2007.01.005
更新日期:2007-06-01 00:00:00
abstract::Hemoplasmosis caused by Mycoplasma spp. have been associated with major economic losses in the global dairy production. Hemoplasma studies in the Philippines are limited despite its potential impact. This study mainly aimed to detect the presence of hemoplasma species in dairy water buffaloes and cattle and know their...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2019.02.004
更新日期:2019-06-01 00:00:00
abstract::Although there is a great diversity of techniques and antigens used in the serodiagnosis of canine visceral leishmaniasis (CVL), total sensitivity and specificity have not yet been found. Since the use of amastigote forms in the indirect immunofluorescence assay has shown an improvement in the specificity of the test ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2020.102177
更新日期:2020-12-01 00:00:00
abstract::"Below is an essay by Prof. Tanabe originally written in Japanese. It gives an insight to Prof. Tanabe's inquiring mind and his approach to science. He also seek, as always, to inspire and nudge the young to scientific discovery". ...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2014.11.010
更新日期:2015-06-01 00:00:00
abstract::The advances in microscopy combined to the invaluable progress carried by the utilization of molecular, immunological or immunochemical markers and the implementation of more powerful imaging technologies have yielded great improvements to the knowledge of the interaction between microorganisms and their hosts, notabl...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2013.07.011
更新日期:2014-02-01 00:00:00
abstract::The parasite Giardia intestinalis undergoes a differentiation process that allows it to infect its mammal host. That process is excystation. We examined the importance of protein phosphorylation during the passage from cyst to trophozoite. Cysts obtained from patients with giardiasis were excysted in vitro and the sol...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2009.10.005
更新日期:2010-03-01 00:00:00
abstract::Tick-borne protozoan and rickettsial diseases are a major threat to livestock in tropical and sub-tropical regions of Africa. In this study we investigated the presence and distribution of Theileria spp., Babesia ovis, Anaplasma ovis, Anaplasma phagocytophilum, Ehrlichia ruminantium and SFG Rickettsia in sheep and goa...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2017.11.002
更新日期:2018-04-01 00:00:00
abstract::The asexual blood stages of the Plasmodium falciparum parasite are responsible for inducing the clinical symptoms and the most severe presentations of malaria infection that causes frequent mortality and morbidity in tropical and subtropical areas of the world, making the blood stages of infection a key target of new ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2018.05.012
更新日期:2018-10-01 00:00:00
abstract::Taeniasis/cysticercosis has been reported from several provinces of Indonesia: Papua (=former Irian Jaya), Bali, North Sumatra, East Nusa Tenggara, South East Sulawesi, Lampung, North Sulawesi, Jakarta, West Kalimantan, and East Java. The highest level of endemicity of taeniasis/cysticercosis has been found in Papua. ...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2005.11.025
更新日期:2006-01-01 00:00:00
abstract::Diplozoids (Diplozoidae, Monogenea) are fish ectoparasites with a direct life cycle without intermediate hosts. Their free swimming larva, the oncomiracidium, hatches from eggs, invades a fish host and metamorphoses into a post-oncomiracidial larval stage, the diporpa. Later, two diporpae fuse and live as a pair in cr...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2007.01.010
更新日期:2007-09-01 00:00:00
abstract::The necropsy of an adult male leopard, Panthera pardus, shot in the Kruger National Park, revealed the presence of large numbers of Armillifer armillatus nymphs in the intestine, liver, spleen, mesentery, peritoneal fold, mediastinum and lungs. The animal had been observed to be blind in the right eye and severely deb...
journal_title:Parasitology international
pub_type:
doi:10.1016/j.parint.2019.102029
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND/AIMS:The aim of this study was to determine the prevalence and significance of intestinal protozoa, specially Blastocystis spp., and to perform PCR-based subtype classification for understanding the importance of Blastocystis spp. in the pathogenesis of gastrointestinal disorders in post-traumatic splenectom...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.12.004
更新日期:2016-12-01 00:00:00
abstract::Genetic diversity of Plasmodium falciparum is intimately associated with morbidity, mortality and malaria control strategies. It is therefore imperative to study genetic makeup and population structure of this parasite in endemic areas. In Kong Mong Tha, an isolated village in western Thailand, the majority of P. falc...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2013.09.011
更新日期:2015-06-01 00:00:00
abstract::A cat excreting Echinococcus multilocularis eggs was recently identified in Hokkaido, representing the first such observation in Japan. The cat was raised free-range and frequently ate rodents. Fecal egg examination revealed eggs of taeniids (EPG: 440) and Spirometra spp. (EPG: >1000). PCR targeting part of the mitoch...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2008.07.001
更新日期:2008-12-01 00:00:00
abstract::Extralymphatic filariasis is an uncommon phenomenon that can be caused by several lymphatic filarial species, including zoonotic filaria of animal origins. In this study, we report a case of a 64-year-old Thai woman who presented with a lump in her left breast that was diagnosed with invasive ductal carcinoma. At the ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2020.102203
更新日期:2021-02-01 00:00:00
abstract::Cystic echinococcosis is a zoonotic disease caused by the larval stage of the cestode Echinococcus granulosus. The drugs commonly used against cystic echinococcosis are benzimidazoles. Unfortunately, 20%-40% of cases do not respond favorably to such chemotherapy. Consequently, the search of new therapeutic alternative...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.06.005
更新日期:2015-10-01 00:00:00
abstract::Gastrointestinal parasites including Eimeria spp. are known to affect domestic animal productivity causing watery or lethal bloody diarrhea. However, there are few reports on the detailed distribution of bovine Eimeria spp. in cattle, particularly in developing tropical and sub-tropical areas. Using a total of 289 fec...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2019.101927
更新日期:2019-10-01 00:00:00
abstract::Toxoplasmosis is a concern in both human and veterinary medicine, and the consumption of undercooked meat infected with Toxoplasma gondii is a major risk factor in human infection. Establishing the prevalence of the parasite in food-producing livestock is essential to reduce the risk of human infection. This study aim...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.07.004
更新日期:2015-12-01 00:00:00
abstract::Helminths are able to modulate and suppress the hosts' immune response in order to promote their own survival. This ability to alter immune responses could be of potential detriment to the host if it interferes with the development of protective immune responses against other infections. However, helminth infections h...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2009.02.001
更新日期:2009-06-01 00:00:00
abstract::This report describes a rare case of ophthalmic dirofilariasis in a 2-year-old boy with redness, irritation, pain and foreign body sensation in the right eye. Slit lamp examination demonstrated a thread-like whitish nematode in the anterior chamber of the right eye that twisted around itself. The nematode worm (35mm l...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2016.10.022
更新日期:2017-02-01 00:00:00
abstract::A recombinant pore-forming peptide of Clonorchis sinensis, clonorin, was evaluated for serodiagnostic reagent of clonorchiasis by enzyme-linked immunosorbent assay detecting IgG antibody. Recombinant clonorin showed 100% specificity and low sensitivity for sera of human clonorchiasis. In contrast, C. sinensis crude an...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/s1383-5769(03)00002-3
更新日期:2003-06-01 00:00:00
abstract::Neospora caninum is an intracellular protozoan that infects many domestic and wild animals. Domestic dogs and other canids function as definitive hosts, while other mammals serve as natural intermediate hosts. In the present study, the brain tissues of bats collected in Yunnan Province, Southern China were tested by N...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2018.03.002
更新日期:2018-08-01 00:00:00
abstract::Three species of the genus Capsala including Capsala naffari n. sp., C. neothunni (Yamaguti, 1968) and C. nozawae (Goto, 1894) are recorded and described from the buccal cavity of mackerel tuna Euthynnus affinis caught from Emirate coasts. Capsala naffari can be differentiated by its lateral spiniform teeth, which ext...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/s1383-5769(02)00033-8
更新日期:2002-12-01 00:00:00
abstract::Visceral leishmaniasis (VL) is a life-threatening vector borne disease caused by the Leishmania donovani species complex. In Nepal, it is transmitted to humans by L donovani infected Phlebotomus argentipes sand flies [12]. The pathogenesis of VL is complex, and the clinical presentation ranges from asymptomatic infect...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2020.102236
更新日期:2021-02-01 00:00:00