Abstract：
:Helminths are able to modulate and suppress the hosts' immune response in order to promote their own survival. This ability to alter immune responses could be of potential detriment to the host if it interferes with the development of protective immune responses against other infections. However, helminth infections have also been suggested to be beneficial in the control of excessive inflammatory reactions. In this review I will highlight some of the data suggesting both positive and negative effects of helminth infections in humans and in experimental models.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Helmby Hdoi
10.1016/j.parint.2009.02.001subject
Has Abstractpub_date
2009-06-01 00:00:00pages
121-7issue
2eissn
1383-5769issn
1873-0329pii
S1383-5769(09)00027-0journal_volume
58pub_type
杂志文章,评审abstract：:Toxoplasma gondii is a protozoan parasite that infects a wide variety of warm-blooded animals and humans, in which it causes opportunistic disease. As an obligate intracellular parasite, T. gondii must invade a host cell to survive and replicate during infection. Recent studies suggest that T. gondii secretes a variet...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/s1383-5769(98)00042-7
更新日期：1999-03-01 00:00:00
abstract：:Malaria is caused by five species of Plasmodium in humans. Microscopy is currently used for pathogen detection, requiring considerable training and technical expertise as the parasites are often difficult to differentiate morphologically. Rapid diagnostic tests are as reliable as microscopy and offer faster diagnoses ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2018.01.005
更新日期：2018-06-01 00:00:00
abstract：:The prevalence of Theileria equi and Babesia caballi was determined in equid blood samples in five provinces of the Black Sea region of Turkey by using the indirect fluorescent antibody test (IFAT). Of 153 samples, 53 (34.6%) and 33 (21.5%) were seropositive to B. caballi and T. equi, respectively. In addition, 8 (5.2...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2007.12.009
更新日期：2008-06-01 00:00:00
abstract：:The discovery of new compounds active against Toxoplasma gondii is extremely important due to the severe disease caused by this pathogen in immunocompromised hosts and to congenital infection. Type II fatty acid biosynthesis has shown to be a promising target for drug intervention in toxoplasmosis. Here we describe th...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.08.004
更新日期：2009-12-01 00:00:00
abstract：:Intestinal mucous cell numbers and their glycoconjugate composition were investigated by histochemical methods in uninfected chub, Squalius cephalus, and in conspecifics naturally parasitised with the acanthocephalan Pomphorhynchus laevis. A sub-population of 42 chub from the River Tiber (Perugia, Italy) were sampled ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2014.11.018
更新日期：2015-04-01 00:00:00
abstract：:The procyclic form of Trypanosoma brucei expresses procyclin surface glycoproteins with unusual glycosylphosphatidylinositol-anchor side chain structures that contain branched N-acetyllactosamine and lacto-N-biose units. The glycosyltransferase TbGT8 is involved in the synthesis of the branched side chain through its ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2014.01.007
更新日期：2014-06-01 00:00:00
abstract：:Malaria is a disease caused by Plasmodium parasites that affects hundreds of millions of people. Plasmodium proteases are involved in invasion, erythrocyte egress and degradation of host proteins. Falcipains are well-studied cysteine peptidases located in P. falciparum food vacuoles that participate in hemoglobin degr...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2017.12.005
更新日期：2018-04-01 00:00:00
abstract：:Coding regions of double stranded RNA molecules from 3 human faecal samples containing Cryptosporidium hominis, C. felis and C. meleagridis were characterised by sequencing and compared with that previously obtained for C. parvum. Sequences outside the coding regions were also obtained. Overall similarities of between...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2006.06.006
更新日期：2006-12-01 00:00:00
abstract：:There has long been a debate as to the specific status of the cestode Taenia asiatica, with some people regarding it as a distinct species and some preferring to recognize it as a strain of Taenia saginata. The balance of current opinion seems to be that T. asiatica is a distinct species. In this study we performed an...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.10.007
更新日期：2010-03-01 00:00:00
abstract：:The parasite Entamoeba histolytica causes intestinal amebiasis and amebic liver abscess as its main extraintestinal manifestation. To study the in vivo events related to inflammation and the interactions between hosts and parasites during amebiasis, we designed a novel model of host-parasite interactions using cellulo...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2016.08.009
更新日期：2016-12-01 00:00:00
abstract：:The complete mitochondrial (mt) genome sequence of Triodontophorus brevicauda, an intestinal equine nematode parasite was determined for the first time. The circular T. brevicauda mt genome is 14,305 bp in length and contains 36 genes, of which 12 code for protein, 22 for transfer RNA, and two for ribosomal RNA, and l...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.06.006
更新日期：2015-10-01 00:00:00
abstract：:Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) expressed on the surface of parasitized red blood cells (PRBCs) mediate adhesion of PRBCs to host vascular endothelial receptors and is considered responsible for pathogenesis of severe P. falciparum malaria. The present study was undertaken to measure cell...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2006.11.003
更新日期：2007-03-01 00:00:00
abstract：:Leishmaniasis is one of the major infectious diseases affecting the poorest regions of the world. The present study evaluated the antileishmanial activity of a guaianolide purified from the hydroalcoholic extract of aerial parts of Tanacetum parthenium (L.) Schultz Bip. The isolated compound showed activity against th...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2010.08.005
更新日期：2010-12-01 00:00:00
abstract：:We present evidence demonstrating that genes encoding enzymes essential for successful blood-feeding are differentially induced in the midgut of the hard tick Haemaphysalis longicornis. Three serine proteinase genes (HlSP, HlSP2 and HlSP3) isolated from H. longicornis midgut exhibit protein sequence similarity with ot...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2008.08.003
更新日期：2008-12-01 00:00:00
abstract：:Lymphatic filariasis is endemic in India. Out of 128 million infected individuals worldwide, India accounts for 48 million cases [Manson's Tropical Diseases, 21st Ed. p 1488]. Filariasis can have protean manifestations, but Tropical pulmonary eosinophilia and chyluria are unusual manifestations reported mainly from So...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2007.03.002
更新日期：2007-09-01 00:00:00
abstract：:Alleviating morbidity due to lymphatic filariasis (LF)-especially in elderly patients who are rather ignorant-is presently the biggest challenge for the national filariasis campaign. We introduced two follow-up schemes and compared each other to address three key programmatic issues (1) locating patients, (2) educatin...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2017.11.005
更新日期：2018-04-01 00:00:00
abstract：:Neospora caninum is an important cause of abortion in cattle worldwide. Dogs act as final hosts shedding oocysts in the environment. They can also harbour the extraintestinal stage of the parasite and this may be associated with a fairly rare neuromuscular condition. The sera of 781 dogs from the Algiers District were...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.08.008
更新日期：2009-12-01 00:00:00
abstract：:Neosporosis caused by Neospora caninum is a serious disease in cattle and dogs worldwide. It is the major cause of abortion and neonatal mortality in cattle. In this study, we evaluated the anti-N. caninum activity of Chinese medicine extracts (curcumin, artemether), herbicides (atrazine, glyphosate), anticoccidiosis ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.08.002
更新日期：2015-12-01 00:00:00
abstract：:Three species of the genus Capsala including Capsala naffari n. sp., C. neothunni (Yamaguti, 1968) and C. nozawae (Goto, 1894) are recorded and described from the buccal cavity of mackerel tuna Euthynnus affinis caught from Emirate coasts. Capsala naffari can be differentiated by its lateral spiniform teeth, which ext...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(02)00033-8
更新日期：2002-12-01 00:00:00
abstract：:We have previously reported a significant decrease in serum PON1 activity after Nippostrongylus brasiliensis infection in Wistar rats in association with the inflammatory response mounted against the parasite in the migratory phase of infection. However, the roles of intestinal phase and the associated oxidative stres...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.03.001
更新日期：2009-06-01 00:00:00
abstract：:Toxoplasmosis is a concern in both human and veterinary medicine, and the consumption of undercooked meat infected with Toxoplasma gondii is a major risk factor in human infection. Establishing the prevalence of the parasite in food-producing livestock is essential to reduce the risk of human infection. This study aim...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.07.004
更新日期：2015-12-01 00:00:00
abstract：:A strategy to engineer a strain of Culex mosquitoes refractory to filarial transmission is described. A requirement for success of the strategy is identification of a flight muscle-specific promoter that functions in the mosquito. A GFP marker gene under the control of the promoter region of the Drosophila melanogaste...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2004.04.002
更新日期：2004-12-01 00:00:00
abstract：:Cystic echinococcosis is a zoonotic disease caused by the larval stage of the cestode Echinococcus granulosus. The drugs commonly used against cystic echinococcosis are benzimidazoles. Unfortunately, 20%-40% of cases do not respond favorably to such chemotherapy. Consequently, the search of new therapeutic alternative...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.06.005
更新日期：2015-10-01 00:00:00
abstract：:Visceral leishmaniasis (VL) is a life-threatening vector borne disease caused by the Leishmania donovani species complex. In Nepal, it is transmitted to humans by L donovani infected Phlebotomus argentipes sand flies [12]. The pathogenesis of VL is complex, and the clinical presentation ranges from asymptomatic infect...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102236
更新日期：2021-02-01 00:00:00
abstract：:Marine fishes represent the important components of the diet in the coastal areas of China and they are also natural hosts of various parasites. However, to date, little is known about the occurrence of ascaridoid parasites in the frequently consumed marine fishes in China. In order to determine the presence of ascari...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.11.002
更新日期：2016-04-01 00:00:00
abstract：:The asexual erythrocytic cycle of the protozoan parasite Plasmodium falciparum is responsible for the pathogenesis of malaria and causes the overwhelming majority of malaria deaths. Rapidly increasing parasitaemia during this 48hour cycle threatens the survival of the human host and the parasite prior to transmission ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2016.07.007
更新日期：2016-12-01 00:00:00
abstract：:The accurate characterization of Schistosoma japonicum has important implications for analyzing genetic variation and would provide basic data for disease control. Previous studies using proteins, coding sequences, and especially antigen-coding genes showed lower genetic variation among S. japonicum isolates from main...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.01.008
更新日期：2011-06-01 00:00:00
abstract：:European liver fluke (Opisthorchis felineus) and Asian liver fluke (Opisthorchis viverrini) are similar in morphology but comparative pathology of the infections has not been described. We therefore did comparative histopathology of both parasites in an experimental animal model. The study was conducted in 3 groups of...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.08.005
更新日期：2012-03-01 00:00:00
abstract：:Dientamoeba fragilis is an intestinal protozoan, an inhabitant of the human gastrointestinal tract, with a worldwide distribution. The reported prevalence of D. fragilis varies worldwide in different populations between 0.3% and 82.9%, and its role as a pathogen is still unclear. The parasite has been identified in th...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102227
更新日期：2021-02-01 00:00:00
abstract：:Taeniasis/cysticercosis has been reported from several provinces of Indonesia: Papua (=former Irian Jaya), Bali, North Sumatra, East Nusa Tenggara, South East Sulawesi, Lampung, North Sulawesi, Jakarta, West Kalimantan, and East Java. The highest level of endemicity of taeniasis/cysticercosis has been found in Papua. ...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2005.11.025
更新日期：2006-01-01 00:00:00
