Abstract:
:A strategy to engineer a strain of Culex mosquitoes refractory to filarial transmission is described. A requirement for success of the strategy is identification of a flight muscle-specific promoter that functions in the mosquito. A GFP marker gene under the control of the promoter region of the Drosophila melanogaster act88F gene was inserted into the genome of Culex quinquefasciatus. Transformation was confirmed by Mendelian genetics. Hybridization of a genomic Southern blot to a radiolabeled probe verified that the entire donor plasmid integrated into the mosquito genome. GFP expression in the transgenic mosquitoes was restricted to the flight muscles.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Allen ML,Christensen BMdoi
10.1016/j.parint.2004.04.002subject
Has Abstractpub_date
2004-12-01 00:00:00pages
307-14issue
4eissn
1383-5769issn
1873-0329pii
S1383576904000601journal_volume
53pub_type
杂志文章abstract::The asexual blood stages of the Plasmodium falciparum parasite are responsible for inducing the clinical symptoms and the most severe presentations of malaria infection that causes frequent mortality and morbidity in tropical and subtropical areas of the world, making the blood stages of infection a key target of new ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2018.05.012
更新日期:2018-10-01 00:00:00
abstract::This study aims to detect the antischistosomal properties of the plants' Chenopodium ambrosioides, Conyza dioscorides and Sesbania sesban methanol extract against Schistosoma mansoni in infected mice, including determination of total protein and albumin levels and the activities of alanine and aspartate transaminases ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2011.06.016
更新日期:2011-12-01 00:00:00
abstract::Fasciola flukes from eastern India were characterized on the basis of spermatogenesis status and nuclear ITS1. Both Fasciola gigantica and aspermic Fasciola flukes were detected in Imphal, Kohima, and Gantoku districts. The sequences of mitochondrial nad1 were analyzed to infer their phylogenetical relationship with n...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.04.004
更新日期:2015-10-01 00:00:00
abstract::The studies on Cryptosporidium infections of animals in Turkey mostly rely on microscopic observation. Few data are available regarding the prevalence of Cryptosporidium genotypes and subtypes infection. The aim of this study is to analyse the detection of Cryptosporidium genotypes and subtypes from young ruminants. A...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2020.102163
更新日期:2020-12-01 00:00:00
abstract::Visceral leishmaniasis (VL) is a life-threatening vector borne disease caused by the Leishmania donovani species complex. In Nepal, it is transmitted to humans by L donovani infected Phlebotomus argentipes sand flies [12]. The pathogenesis of VL is complex, and the clinical presentation ranges from asymptomatic infect...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2020.102236
更新日期:2021-02-01 00:00:00
abstract::The present work provides a detailed morphological and molecular description of Anoplocephala manubriata in elephants. Adult worms were recovered during an autopsy of a wild elephant in Elephant Transit Home, Udawalawe, Sri Lanka. Necropsy findings revealed a severe cestode infection in the small intestine. These tape...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2017.02.007
更新日期:2017-06-01 00:00:00
abstract::Three species of the genus Capsala including Capsala naffari n. sp., C. neothunni (Yamaguti, 1968) and C. nozawae (Goto, 1894) are recorded and described from the buccal cavity of mackerel tuna Euthynnus affinis caught from Emirate coasts. Capsala naffari can be differentiated by its lateral spiniform teeth, which ext...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/s1383-5769(02)00033-8
更新日期:2002-12-01 00:00:00
abstract::Lymphatic filariasis is endemic in India. Out of 128 million infected individuals worldwide, India accounts for 48 million cases [Manson's Tropical Diseases, 21st Ed. p 1488]. Filariasis can have protean manifestations, but Tropical pulmonary eosinophilia and chyluria are unusual manifestations reported mainly from So...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2007.03.002
更新日期:2007-09-01 00:00:00
abstract::Haintestinum amplum n. g., n. sp. is described from the scrawled cowfish, Acanthostracion quadricornis, collected in the Eastern Gulf of Mexico off Florida, USA. The new species is relatively large and shares characters of the Apocreadiidae and Megaperidae but conforms to the diagnosis of neither. It belongs in a new ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2013.11.007
更新日期:2014-04-01 00:00:00
abstract::Fasciola gigantica is considered the major pathogen causing fasciolosis in Africa; however, molecular characterization of this fluke has not been adequately elucidated. It is important to scientifically elucidate the dispersal history of F. gigantica by analyzing its genetic diversity. Fasciola flukes from Nigeria wer...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2016.10.010
更新日期:2017-02-01 00:00:00
abstract::In this work, we characterized the gene encoding iron superoxide dismutase-A (FeSOD-A) in wild-type (WTS) and antimony-resistant (SbR) L. (Viannia) braziliensis and L. (Leishmania) infantum lines, which were selected in vitro. FeSOD-A transcript and protein expression were similar in all tested lines; however, specifi...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2014.11.001
更新日期:2015-04-01 00:00:00
abstract::The taxonomic framework of Ligophorus, monogenean specialists of the gills of grey mullets (Mugilidae), is evaluated and its interspecific relationships are assessed for the first time using molecular data. The position of Ligophorus within the paraphyletic Ancyrocephalinae is re-assessed based on newly sequenced spec...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2012.06.004
更新日期:2012-12-01 00:00:00
abstract::Alveolar echinococcosis (AE) of the liver caused by the metacestode of the fox tapeworm Echinococcus multilocularis is characterized by a multivesicular structure surrounded by an extensive fibro-inflammatory host reaction. The lesions behave like a slow-growing liver cancer, without sharp limits between the parasitic...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2005.11.053
更新日期:2006-01-01 00:00:00
abstract::Pinworm parasites commonly infect laboratory mice with high prevalence even in well-managed animal colonies. Although often considered as irrelevant, these parasites if undetected may significantly interfere with the experimental settings and alter the interpretation of final results. There are a few reports documenti...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2005.10.005
更新日期:2006-06-01 00:00:00
abstract::Two hyperapolytic species of Acanthobothrium Blanchard, 1848 have been collected from Discopyge tschudii Heckel, 1846 and Zapteryx brevirostris (Müller et Henle) along the coast of Argentina. Acanthobothrium stefaniae sp. n. from D. tschudii is a category one species (i.e., it is less than 15 mm in total length, posse...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2018.04.001
更新日期:2018-08-01 00:00:00
abstract::The parasite Entamoeba histolytica causes intestinal amebiasis and amebic liver abscess as its main extraintestinal manifestation. To study the in vivo events related to inflammation and the interactions between hosts and parasites during amebiasis, we designed a novel model of host-parasite interactions using cellulo...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2016.08.009
更新日期:2016-12-01 00:00:00
abstract::The prevalence of Theileria equi and Babesia caballi was determined in equid blood samples in five provinces of the Black Sea region of Turkey by using the indirect fluorescent antibody test (IFAT). Of 153 samples, 53 (34.6%) and 33 (21.5%) were seropositive to B. caballi and T. equi, respectively. In addition, 8 (5.2...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2007.12.009
更新日期:2008-06-01 00:00:00
abstract::Three different monoclonal antibodies were produced against Trypanosona cruzi proteasomes. These antibodies were shown to react with a single 27-kDa band on immunoblots of purified proteasomes. Using a 7E5 monoclonal antibody (IgG1) that recognized the alpha5 subunit of protozoan protease we have studied the intracell...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2009.07.012
更新日期:2009-12-01 00:00:00
abstract::There is limited knowledge about parasites of the endangered Ryukyu long-furred rat, Diplothrix legata (Murinae, Rodentia) endemic to Okinawa, Tokunoshima, and Amami-Oshima Islands in Japan. In the present study, postmortem histopathological examination of an individual found on Amami-Oshima Island revealed a mixed he...
journal_title:Parasitology international
pub_type:
doi:10.1016/j.parint.2020.102058
更新日期:2020-06-01 00:00:00
abstract::Brazilian sardine is emerging as a promising species in Aquaculture. This study describes for the first time a case of parasitic infestation by Amyloodinium in Brazilian sardines Sardinella brasiliensis obtained from natural spawning in captivity. The sardines kept in nurseries were naturally parasitized by the amylod...
journal_title:Parasitology international
pub_type:
doi:10.1016/j.parint.2020.102091
更新日期:2020-06-01 00:00:00
abstract::Extralymphatic filariasis is an uncommon phenomenon that can be caused by several lymphatic filarial species, including zoonotic filaria of animal origins. In this study, we report a case of a 64-year-old Thai woman who presented with a lump in her left breast that was diagnosed with invasive ductal carcinoma. At the ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2020.102203
更新日期:2021-02-01 00:00:00
abstract::Few anthelminthic drugs are available for human use despite the significant burden caused by helminth infections. We studied the activities of mangostin, a major bioactive xanthone isolated from the pericarp and fruit of Garcinia mangostana and of the synthetic derivative mangostin diacetate. Mangostin and mangostin d...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2012.01.004
更新日期:2012-06-01 00:00:00
abstract::Toxoplasma gondii and Neospora caninum are two closely related protozoan parasites which can cause abortion and significant economic losses in sheep and goats. However, it is yet to know whether black-bone sheep and goats are infected with T. gondii and N. caninum in China. In the present investigation, the seropreval...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2019.102041
更新日期:2020-04-01 00:00:00
abstract::Structure and pattern of helminth component communities parasitizing grebes and loons are poorly understood. Here we analyze the prevalence, intensity and diversity of helminths in 505 Czech grebes (Podiceps cristatus, Podiceps nigricollis, Tachybaptus ruficollis) and loons (Gavia arctica, Gavia stellata) collected be...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.05.012
更新日期:2015-10-01 00:00:00
abstract::Leishmaniasis is one of the major infectious diseases affecting the poorest regions of the world. The present study evaluated the antileishmanial activity of a guaianolide purified from the hydroalcoholic extract of aerial parts of Tanacetum parthenium (L.) Schultz Bip. The isolated compound showed activity against th...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2010.08.005
更新日期:2010-12-01 00:00:00
abstract::Schistosomiasis is endemic in Indonesia in two isolated areas, Lindu valley and Napu valley, both located in the Province of Central Sulawesi. In 1940, a prevalence survey was initiated in Lake Lindu, which indicated a Schistosoma japonicum infection prevalence of 56% among the population of Anca, Tomado and Langko vi...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2008.04.008
更新日期:2008-09-01 00:00:00
abstract::Control of morbidity associated with schistosomiasis via chemotherapy largely relies on the drug praziquantel. Repeated therapy with praziquantel has created concerns about the possible selection of resistant worms and necessitated the search for novel drugs to treat schistosomiasis. Here, a murine model was infected ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2018.03.006
更新日期:2018-08-01 00:00:00
abstract::Host-parasite interaction during infection with the liver fluke Opisthorchis viverrini plays an important role in opisthorchiasis-associated cholangiocarcinoma via nitric oxide (NO) production. Host cells induce nitric oxide synthase (NOS)-dependent DNA damage and secrete Ras-related C3 botulinum toxin substrate (Rac)...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2011.06.017
更新日期:2012-03-01 00:00:00
abstract::The salivary glands of Rhipicephalus sanguineus males at stages: unfed (control), at day seven post-attachment, and at days three and seven post-detachment from the host were examined using methods of enzymatic analysis and cell viability. At these stages of feeding, different staining patterns were observed in the ce...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2008.04.012
更新日期:2008-09-01 00:00:00
abstract::This paper presents the morphological, histological, molecular and ultrastructural data on Myxobolus lomi sp. nov., a parasite of the gill filaments of Prochilodus lineatus from the Peixes River (48º06'38″W; 22º 49'53.1″S), São Paulo State, Brazil. From 20 P. lineatus specimens examined, 90.0% (n=18) were infected. Th...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2013.11.008
更新日期:2014-04-01 00:00:00