Abstract：
:Dientamoeba fragilis is an intestinal protozoan, an inhabitant of the human gastrointestinal tract, with a worldwide distribution. The reported prevalence of D. fragilis varies worldwide in different populations between 0.3% and 82.9%, and its role as a pathogen is still unclear. The parasite has been identified in the faeces of asymptomatic patients and with different acute and chronic symptoms, like abdominal pain, diarrhoea, flatulence, nausea and vomiting. The aims of this study were to evaluate the prevalence of D. fragilis in the North-East of Italy, and the clinical improvement of symptoms after recommended treatment with paromomycin or metronidazole. Furthermore, a literature review of D. fragilis prevalence studies in Italy was carried out to show the Italian situation. Of 575 enrolled people, 85 (14.8%) were positive for D. fragilis. The most prevalent symptoms were abdominal pain 28.2%, anal itching 27.1%, watery diarrhoea 18.8%, meteorism 16.5% and nausea/lack of appetite 14.1%. The high rate of anal itching was unexpected, because it wasn't a common symptom. 32 patients were co-infected with B. hominis (37.7%) and three with G. lamblia (3.5%). Our study showed paromomycin had a high efficacy for treatment of D. fragilis infections 100.0% (45/45), while caution must be used when using metronidazole 53.3% (24/40). We recommend paromomycin for empirical treatment, given its great effectiveness in our population.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Clemente L,Pasut M,Carlet R,Ruscio M,Fontana Fdoi
10.1016/j.parint.2020.102227subject
Has Abstractpub_date
2021-02-01 00:00:00pages
102227eissn
1383-5769issn
1873-0329pii
S1383-5769(20)30177-Xjournal_volume
80pub_type
杂志文章abstract：:There has long been a debate as to the specific status of the cestode Taenia asiatica, with some people regarding it as a distinct species and some preferring to recognize it as a strain of Taenia saginata. The balance of current opinion seems to be that T. asiatica is a distinct species. In this study we performed an...
journal_title：Parasitology international
pub_type： 杂志文章
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journal_title：Parasitology international
pub_type： 杂志文章
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journal_title：Parasitology international
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doi：10.1016/s1383-5769(02)00004-1
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journal_title：Parasitology international
pub_type： 杂志文章
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journal_title：Parasitology international
pub_type： 杂志文章
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journal_title：Parasitology international
pub_type： 杂志文章
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.08.004
更新日期：2009-12-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
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更新日期：2000-12-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.12.004
更新日期：2012-06-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.08.005
更新日期：2012-03-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.05.003
更新日期：2009-09-01 00:00:00
abstract：:The parasite Entamoeba histolytica causes intestinal amebiasis and amebic liver abscess as its main extraintestinal manifestation. To study the in vivo events related to inflammation and the interactions between hosts and parasites during amebiasis, we designed a novel model of host-parasite interactions using cellulo...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2016.08.009
更新日期：2016-12-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.05.012
更新日期：2015-10-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2007.09.007
更新日期：2008-03-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2005.06.002
更新日期：2005-12-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2016.02.011
更新日期：2016-10-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.07.002
更新日期：2015-12-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
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更新日期：2020-02-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
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更新日期：2018-08-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2016.07.007
更新日期：2016-12-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
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更新日期：2020-10-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2014.01.007
更新日期：2014-06-01 00:00:00
abstract：:Toxoplasma gondii takes two different life cycle stages within intermediate hosts including humans. Tachyzoites proliferate during the acute stage, and they transform into cysts to establish a chronic infection preferentially in the brain. IFN-γ production by infiltrated CD4+ and CD8+ T cells is required for the preve...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2019.102030
更新日期：2020-06-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(00)00049-0
更新日期：2000-09-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2019.102041
更新日期：2020-04-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2018.01.001
更新日期：2018-06-01 00:00:00
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journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2007.01.010
更新日期：2007-09-01 00:00:00
abstract：:Neospora caninum is an important cause of abortion in cattle worldwide. Dogs act as final hosts shedding oocysts in the environment. They can also harbour the extraintestinal stage of the parasite and this may be associated with a fairly rare neuromuscular condition. The sera of 781 dogs from the Algiers District were...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.08.008
更新日期：2009-12-01 00:00:00
abstract：:Hydroethidine has been used as a viability dye in various haemoparasites, including Plasmodium species. We compared flow cytometric quantification by hydroethidine and thiazole orange in P. falciparum. Dead parasites that did not develop or replicate exhibited high levels of DNA fragmentation and abnormal microscopic ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2012.07.002
更新日期：2012-12-01 00:00:00
abstract：:In murine leishmaniasis, the induction of the T-helper type 1 (Th1) response contributes to infection resistance, whereas the establishment of the Th2 response makes the mice susceptible to infection. Interleukin-12 (IL-12) plays a pivotal role in the diversification of immune responses to the Th1 type. In this study,...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(01)00070-8
更新日期：2001-07-01 00:00:00
