Abstract:
:Research into the roles played by Hox and related homeotic gene families in the diverse and complex developmental programmes exhibited by parasitic flatworms (Platyhelminthes) can hardly be said to have begun, and thus presents considerable opportunity for new research. Although featured in some of the earliest screens for homeotic genes outside Drosophila and mice, surveys in parasitic flatworms are few in number and almost nothing is yet known of where or when the genes are expressed during ontogeny. This contrasts sharply with a significant body of literature concerning Hox genes in free-living flatworms which have long served as models for the study of regeneration and the maintenance of omnipotent cell lines. Nevertheless, available information suggests that the complement of Hox genes and other classes of homeobox-containing genes in parasitic flatworms is typical of their free-living cousins and of other members of the Lophotrochozoa. Recent work on Schistosoma combined with information on Hox gene expression in planarians indicates that at least some disruption of the clustered genomic arrangement of the genes, as well as of the strict spatial and temporal colinear patterns of expression typical in other groups, may be characteristic of flatworms. However, available data on the genomic arrangement and expression of flatworm Hox genes is so limited at present that such generalities are highly tenuous. Moreover, a basic underlying pattern of colinearity is still observed in their spatial expression patterns making them suitable as cell or region-specific markers. I discuss a number of fundamental developmental questions and some of the challenges to addressing them in relation to each of the major parasitic lineages. In addition, I present newly characterized Hox genes from the model tapeworm Hymenolepis and analyze these by Bayesian inference together with >100 Hox and ParaHox homeodomains of flatworms and select lophotrochozoan taxa, providing a phylogenetic scaffold for their identification.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Olson PDdoi
10.1016/j.parint.2007.09.007subject
Has Abstractpub_date
2008-03-01 00:00:00pages
8-17issue
1eissn
1383-5769issn
1873-0329pii
S1383-5769(07)00127-4journal_volume
57pub_type
杂志文章,评审abstract::Malaria is a disease caused by Plasmodium parasites that affects hundreds of millions of people. Plasmodium proteases are involved in invasion, erythrocyte egress and degradation of host proteins. Falcipains are well-studied cysteine peptidases located in P. falciparum food vacuoles that participate in hemoglobin degr...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2017.12.005
更新日期:2018-04-01 00:00:00
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journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2006.08.004
更新日期:2006-12-01 00:00:00
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journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/s1383-5769(00)00069-6
更新日期:2001-03-01 00:00:00
abstract::A schistosome genome project was initiated by the World Health Organization in 1994 with the notion that the best prospects for identifying new targets for drugs, vaccines, and diagnostic development lie in schistosome gene discovery, development of chromosome maps, whole genome sequencing and genome analysis. Schisto...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2004.01.009
更新日期:2004-06-01 00:00:00
abstract::Visceral pentastomiasis (porocephalosis) caused by Armillifer armillatus larvae was incidentally diagnosed in a female striped hyena (Hyaena hyaena) of unknown age which died unexpectedly in 2013. The hyena had been imported from Tanzania 8years earlier and have been since then in a zoo in Chiang Mai, northern Thailan...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.10.004
更新日期:2016-02-01 00:00:00
abstract::Diphyllobothrium hottai Yazaki, Fukumoto & Abe, 1988 was described based on the morphology of adult worms recovered from golden hamsters that had been experimentally infected with plerocercoids obtained from Japanese surf smelts (Hypomesus pretiosus japonicus) and olive rainbow smelts (Osmerus eperlanus mordax). Altho...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2016.06.011
更新日期:2016-10-01 00:00:00
abstract::Strongyloides stercoralis is a parasitic nematode and a major pathogen responsible for human strongyloidiasis. The presence of this species in the dog population has led to an interest in studying the phylogenetic relationships among Strongyloides spp. in carnivore hosts. In the present study, Strongyloides spp. from ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2020.102151
更新日期:2020-10-01 00:00:00
abstract::In Shiqu County of the Qinghai-Tibet plateau, many wild and domestic mammals are involved in the transmission cycles of Echinococcus spp. Echinococcus multilocularis and Echinococcus granulosus genotype G1 (sheep strain) are sympatrically distributed in the plateau. In 1995, we identified a unique strobilate stage of ...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2005.11.035
更新日期:2006-01-01 00:00:00
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journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2011.01.008
更新日期:2011-06-01 00:00:00
abstract::Henneguya guanduensis was originally described as a gill parasite of the Hoplosternum litoralle, a siluriform fish belonging to the Callichthyidae family. A study was undertaken with 58 specimens of H. litoralle taken from Batalha River in the state of São Paulo. The fish were collected and examined searching for lesi...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2019.01.009
更新日期:2019-06-01 00:00:00
abstract::Fasciola flukes from eastern India were characterized on the basis of spermatogenesis status and nuclear ITS1. Both Fasciola gigantica and aspermic Fasciola flukes were detected in Imphal, Kohima, and Gantoku districts. The sequences of mitochondrial nad1 were analyzed to infer their phylogenetical relationship with n...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.04.004
更新日期:2015-10-01 00:00:00
abstract::The stomach bot fly species in Asian elephants has long been known as Cobboldia elephantis. However, there is no genetic information available for this species to date. Here, we report that a third-instar fly larva was excreted from a captive Asian elephant four months after export from an elephant camp in Myanmar to ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2019.102035
更新日期:2020-04-01 00:00:00
abstract::Newly collected material of Cercopithifilaria rugosicauda from roe deer Capreolus capreolus was analysed and compared to descriptions of C. rugosicauda from Austria and Hungary. The present specimens were assigned to the genus Cercopithifilaria using both morphological and molecular analyses. Complementary morphologic...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2014.07.011
更新日期:2014-12-01 00:00:00
abstract::In the early stage of research on Clonorchis and clonorchiasis, Japanese parasitologists made a tremendous contribution on the elucidation of the life cycle of this parasite and on the epidemiology of the disease. Harujiro Kobayashi first identified cyprinoid fish as the second intermediate hosts for Clonorchis sinens...
journal_title:Parasitology international
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.parint.2011.06.003
更新日期:2012-03-01 00:00:00
abstract::The raccoon dog (Nyctereutes procyonoides viverrinus) is known to acquire canine heartworm (Dirofilaria immitis) infection. We surveyed the prevalence of heartworm infection in free-ranging raccoon dogs in the Nishi-Tama (Tokyo) and Kanagawa areas of Japan. A total of 75 raccoon dog carcasses, including 29 animals fro...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/s1383-5769(00)00049-0
更新日期:2000-09-01 00:00:00
abstract::In murine leishmaniasis, the induction of the T-helper type 1 (Th1) response contributes to infection resistance, whereas the establishment of the Th2 response makes the mice susceptible to infection. Interleukin-12 (IL-12) plays a pivotal role in the diversification of immune responses to the Th1 type. In this study,...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/s1383-5769(01)00070-8
更新日期:2001-07-01 00:00:00
abstract::This review analyzes the literature in search of an answer to the fact that, in general, tapeworms are very difficult to recover. The results and comments of the authors that have searched for Taenia solium, either to define the local prevalence in different countries of Latin America, to assess the efficacy of cestoc...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2005.11.018
更新日期:2006-01-01 00:00:00
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journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2012.09.001
更新日期:2013-02-01 00:00:00
abstract::Haintestinum amplum n. g., n. sp. is described from the scrawled cowfish, Acanthostracion quadricornis, collected in the Eastern Gulf of Mexico off Florida, USA. The new species is relatively large and shares characters of the Apocreadiidae and Megaperidae but conforms to the diagnosis of neither. It belongs in a new ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2013.11.007
更新日期:2014-04-01 00:00:00
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journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/s1383-5769(98)00041-5
更新日期:1999-03-01 00:00:00
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journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2009.07.004
更新日期:2009-12-01 00:00:00
abstract::The present work provides a detailed morphological and molecular description of Anoplocephala manubriata in elephants. Adult worms were recovered during an autopsy of a wild elephant in Elephant Transit Home, Udawalawe, Sri Lanka. Necropsy findings revealed a severe cestode infection in the small intestine. These tape...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2017.02.007
更新日期:2017-06-01 00:00:00
abstract::The salmon louse (Lepeophtheirus salmonis (Krøyer 1837)) is an ectoparasitic copepod which represents a major pathogen of wild and farmed salmonid fishes in the marine environment. In order to facilitate research on this ecologically and economically important parasite, a hatchery and culturing system permitting the c...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2009.08.009
更新日期:2009-12-01 00:00:00
abstract::Roundworms of the genus Baylisascaris are natural parasites primarily of wild carnivores, and they can occasionally cause infection in humans and animals. Infection results in visceral larva migrans and/or neural larva migrans, which can be severe or fatal in some animals. Recently, Baylisascaris nematodes isolated fr...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.03.003
更新日期:2015-10-01 00:00:00
abstract::Two new species of bucephalids (Digenea: Bucephalidae) were found parasitizing freshwater fishes of Argentina. Prosorhynchoides cambapuntaensis sp. n. from Salminus maxillosus (Characidae) is characterised by the tegument covered with two kinds of spines, scale-like spines anteriorly and fine spines posteriorly; uteri...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2004.01.014
更新日期:2004-09-01 00:00:00
abstract::Schistosoma mansoni enzymes play important roles in host-parasite interactions and are potential targets for immunological and/or pharmacological attack. The aim of this study was to comparatively assess the presence of hydrolytic activities (phosphatases, glycosidases, aminopeptidases) in soluble (SF) and membrane (M...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2016.09.015
更新日期:2017-02-01 00:00:00
abstract::There has long been a debate as to the specific status of the cestode Taenia asiatica, with some people regarding it as a distinct species and some preferring to recognize it as a strain of Taenia saginata. The balance of current opinion seems to be that T. asiatica is a distinct species. In this study we performed an...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2009.10.007
更新日期:2010-03-01 00:00:00
abstract::Septin4 (Sept4) belongs to Septin family and may be involved in apoptosis, vesicle trafficking and other cell processes. In this study, we attempted to investigate the effect of Sept4 in hepatic fibrosis induced by Schistosoma japonicum. ICR mice infected with S. japonicum for 12weeks were treated with PBS, Ad-ctr and...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.07.002
更新日期:2015-12-01 00:00:00
abstract::Opisthorchiasis caused by the carcinogenic liver fluke Opisthorchis viverrini is a major foodborne parasitic zoonotic disease in Thailand and neighboring Mekong countries. The infection is associated with several hepatobiliary diseases including cholangiocarcinoma (CCA). The rates of CCA in regions where the parasite ...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2016.11.013
更新日期:2017-08-01 00:00:00
abstract::Brasicystis bennetti Thatcher, 1979 was first described from specimens obtained from the subcutaneous tissues of the mouth and operculum of Plagioscyion squamosissimus from the Amazon River in Brazil, however since 2008, Brasicystis has been considered a genus inquirendum. This study reviews some of the diagnostic cha...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2013.01.001
更新日期:2013-04-01 00:00:00