Abstract:
:Immunodeficient mice were studied to determine their suitability as models in investigating the role of Taenia taeniaeformis larval products in the development of gastric hyperplasia. Recombinant active gene 2 (RAG2)-deficient and severe combined immune-deficient (SCID) mice were studied as candidate animal models. RAG2-deficient mice inoculated orally with T. taeniaeformis eggs developed gastric hyperplasia with alcian blue-periodic acid-Schiff-positive cell proliferation similar to those of rats. SCID mice inoculated with different doses and routes of T. taeniaeformis in vitro-hatched oncospheres and those orally inoculated with eggs resulted also in different degrees of gastric hyperplasia. Influence of inoculation forms of parasite, doses and routes of inoculation on initiation of hyperplastic gastropathy was suggested to be dependent on number and size of developed larvae. Both RAG2-deficient and SCID mice with hyperplastic mucosa were observed with significant loss of parietal cells. Apparent decrease in parietal cell number was observed in SCID mice at 2 weeks after intraperitoneal inoculation with oncospheres before hyperplastic lesions developed. Earliest occurrence of gastric hyperplasia in SCID mice was observed at 3 weeks after oral inoculation of in vitro-hatched oncospheres, sooner than orally inoculated rats. The results suggested that these immunodeficient mice could be used as animal models to study factors involved in T. taeniaeformis-induced gastric mucous cell hyperplasia.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Lagapa JT,Konno K,Oku Y,Nonaka N,Ito M,Kamiya Mdoi
10.1016/s1383-5769(01)00108-8subject
Has Abstractpub_date
2002-03-01 00:00:00pages
81-9issue
1eissn
1383-5769issn
1873-0329pii
S1383576901001088journal_volume
51pub_type
杂志文章abstract::The host-parasite relationship is one of the main themes of modern parasitology. Recent revolutions in science, including the development of various fluorescent proteins/probes and two-photon microscopy, have made it possible to directly visualize and study the mechanisms underlying the interaction between the host an...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2016.02.011
更新日期:2016-10-01 00:00:00
abstract::The procyclic form of Trypanosoma brucei expresses procyclin surface glycoproteins with unusual glycosylphosphatidylinositol-anchor side chain structures that contain branched N-acetyllactosamine and lacto-N-biose units. The glycosyltransferase TbGT8 is involved in the synthesis of the branched side chain through its ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2014.01.007
更新日期:2014-06-01 00:00:00
abstract::Tick-borne protozoan and rickettsial diseases are a major threat to livestock in tropical and sub-tropical regions of Africa. In this study we investigated the presence and distribution of Theileria spp., Babesia ovis, Anaplasma ovis, Anaplasma phagocytophilum, Ehrlichia ruminantium and SFG Rickettsia in sheep and goa...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2017.11.002
更新日期:2018-04-01 00:00:00
abstract::Human intestinal sarcocystosis (HIS), caused by Sarcocystis species, is acquired by eating undercooked meat from sarcocyst-containing cattle (S. hominis, S. heydorni) and pigs (S. suihominis). We report on the detection of human intestinal Sarcocystis infections in a cross-sectional survey of Strongyloides stercoralis...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2017.04.010
更新日期:2017-10-01 00:00:00
abstract::In Shiqu County of the Qinghai-Tibet plateau, many wild and domestic mammals are involved in the transmission cycles of Echinococcus spp. Echinococcus multilocularis and Echinococcus granulosus genotype G1 (sheep strain) are sympatrically distributed in the plateau. In 1995, we identified a unique strobilate stage of ...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2005.11.035
更新日期:2006-01-01 00:00:00
abstract::To evaluate the geographic distribution of Giardia intestinalis genotypes in Nablus, West Bank, Palestine, a genotyping study was performed using clinical fecal samples. Microscopic examination confirmed that 8 of 69 (11.6%) samples were G. intestinalis positive, and subsequent genotyping analyses targeting the small-...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2009.04.002
更新日期:2009-09-01 00:00:00
abstract::Serum samples from 2970 (1400 sows, 1570 fattening) pigs, from 100 farms in the 10 main swine production regions in Spain were tested for antibodies against T. gondii by the modified agglutination test (MAT). Antibodies to T. gondii (MAT 1:25 or higher) were detected in 492 pigs (16.6%, 9.7% in fattening pigs and 24.2...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2010.06.001
更新日期:2010-09-01 00:00:00
abstract::The stomach bot fly species in Asian elephants has long been known as Cobboldia elephantis. However, there is no genetic information available for this species to date. Here, we report that a third-instar fly larva was excreted from a captive Asian elephant four months after export from an elephant camp in Myanmar to ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2019.102035
更新日期:2020-04-01 00:00:00
abstract::Diphyllobothrium hottai Yazaki, Fukumoto & Abe, 1988 was described based on the morphology of adult worms recovered from golden hamsters that had been experimentally infected with plerocercoids obtained from Japanese surf smelts (Hypomesus pretiosus japonicus) and olive rainbow smelts (Osmerus eperlanus mordax). Altho...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2016.06.011
更新日期:2016-10-01 00:00:00
abstract::Strongyloides stercoralis is a parasitic nematode and a major pathogen responsible for human strongyloidiasis. The presence of this species in the dog population has led to an interest in studying the phylogenetic relationships among Strongyloides spp. in carnivore hosts. In the present study, Strongyloides spp. from ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2020.102151
更新日期:2020-10-01 00:00:00
abstract::Marine fishes represent the important components of the diet in the coastal areas of China and they are also natural hosts of various parasites. However, to date, little is known about the occurrence of ascaridoid parasites in the frequently consumed marine fishes in China. In order to determine the presence of ascari...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.11.002
更新日期:2016-04-01 00:00:00
abstract::Fasciola spp. in Myanmar were characterized on the basis of spermatogenesis status and DNA markers of nuclear internal transcribed spacer 1 (ITS1) and mitochondrial NADH dehydrogenase subunit 1 (nad1). We collected 88 adult flukes from Yangon, Lashio, and Myitkyina. Spermatogenesis status was analyzed by the presence ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2011.08.007
更新日期:2011-12-01 00:00:00
abstract::Fasciolosis is an economically important disease of livestock caused by Fasciola hepatica, Fasciola gigantica, and aspermic Fasciola flukes. The aspermic Fasciola flukes have been discriminated morphologically from the two other species by the absence of sperm in their seminal vesicles. To date, the molecular discrimi...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.12.002
更新日期:2016-06-01 00:00:00
abstract::The phospholipid metabolism of Plasmodium falciparum-infected erythrocytes has been shown to be an effective pharmacological target for novel chemotherapy. Thirty-seven monoquaternary ammonium derivatives analogous to choline were screened for their potential antiprotozoal activity against P. falciparum and Leishmania...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2007.09.006
更新日期:2008-06-01 00:00:00
abstract::Several Sarcocystis spp. have carnivores as definitive host and sarcocysts are common in muscles of herbivores (intermediate host). However, sarcocysts have been found in muscles of wild and domestic carnivores suggesting they are intermediate host for some Sarcocystis spp. Here, we report mature sarcocysts in the mus...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2017.01.021
更新日期:2017-06-01 00:00:00
abstract::Gastrointestinal parasites including Eimeria spp. are known to affect domestic animal productivity causing watery or lethal bloody diarrhea. However, there are few reports on the detailed distribution of bovine Eimeria spp. in cattle, particularly in developing tropical and sub-tropical areas. Using a total of 289 fec...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2019.101927
更新日期:2019-10-01 00:00:00
abstract::The largest subunit of eukaryotic RNA polymerase II (RNA Pol II) of several members of Kinetoplastida order and other early diverging eukaryote contains a serine, tyrosine and proline-rich domain in the carboxyl-terminal instead of the typical heptapeptides repeats found in most eukaryotes. The lack of these repeats s...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/s1383-5769(03)00009-6
更新日期:2003-09-01 00:00:00
abstract::The protozoan Trypanosoma cruzi is a parasite exposed to several environmental stressors inside its invertebrate and vertebrate hosts. Although stress conditions are involved in its differentiation processes, little information is available about the stress response proteins engaged in these activities. This work repo...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2017.10.009
更新日期:2018-04-01 00:00:00
abstract::We have previously reported a significant decrease in serum PON1 activity after Nippostrongylus brasiliensis infection in Wistar rats in association with the inflammatory response mounted against the parasite in the migratory phase of infection. However, the roles of intestinal phase and the associated oxidative stres...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2009.03.001
更新日期:2009-06-01 00:00:00
abstract::Schistosomiasis is one of the most prevalent and serious parasitic diseases in the world and remains an important public health problem in China. Screening and discovery of an effective vaccine candidate or new drug target is crucial for the control of this disease. In this study, we cloned a cDNA encoding Schistosoma...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2012.03.005
更新日期:2012-09-01 00:00:00
abstract::Miamiensis avidus causes scuticociliatosis in cultured olive flounders (Paralichthys olivaceus), leading to economic losses in aquaculture in Korea. Quantitative evaluation of the viability of M. avidus is important to develop an effective vaccine or chemotherapeutic agent against it. We used a colorimetric assay base...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2020.102093
更新日期:2020-06-01 00:00:00
abstract::Alternative strategies are being designed to identify candidates among drugs already available on the market that could be used in combination to improve the efficacy of Chagas disease treatment. This work evaluates the effect of the association of clomipramine (CLO) with benznidazole (BZN) for the treatment of experi...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2013.02.004
更新日期:2013-06-01 00:00:00
abstract::Toxoplasma gondii takes two different life cycle stages within intermediate hosts including humans. Tachyzoites proliferate during the acute stage, and they transform into cysts to establish a chronic infection preferentially in the brain. IFN-γ production by infiltrated CD4+ and CD8+ T cells is required for the preve...
journal_title:Parasitology international
pub_type: 杂志文章,评审
doi:10.1016/j.parint.2019.102030
更新日期:2020-06-01 00:00:00
abstract::The accurate characterization of Schistosoma japonicum has important implications for analyzing genetic variation and would provide basic data for disease control. Previous studies using proteins, coding sequences, and especially antigen-coding genes showed lower genetic variation among S. japonicum isolates from main...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2011.01.008
更新日期:2011-06-01 00:00:00
abstract::Owing to the need to combat the spread of acaricide-resistant ticks, the development of long-term biological control has become a hot topic for tick control. In this study, we investigated the pathogenicity of three Beauveria bassiana isolates on the engorged female Rhipicephalus (Boophilus) microplus ticks using diff...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2013.04.008
更新日期:2013-10-01 00:00:00
abstract::The asexual erythrocytic cycle of the protozoan parasite Plasmodium falciparum is responsible for the pathogenesis of malaria and causes the overwhelming majority of malaria deaths. Rapidly increasing parasitaemia during this 48hour cycle threatens the survival of the human host and the parasite prior to transmission ...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2016.07.007
更新日期:2016-12-01 00:00:00
abstract::In the early stage of research on Clonorchis and clonorchiasis, Japanese parasitologists made a tremendous contribution on the elucidation of the life cycle of this parasite and on the epidemiology of the disease. Harujiro Kobayashi first identified cyprinoid fish as the second intermediate hosts for Clonorchis sinens...
journal_title:Parasitology international
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.parint.2011.06.003
更新日期:2012-03-01 00:00:00
abstract::Gnathostomiasis is an emerging zoonosis in Mexico. However, for most endemic zones, the source of human infection has not been established. During 2000-2003, we investigated 2168 vertebrates (2047 fish, 31 amphibians, 4 reptiles, 19 birds and 67 mammals) from 39 localities distributed in nine states. We registered 7 v...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2004.10.001
更新日期:2005-03-01 00:00:00
abstract::The salmon louse (Lepeophtheirus salmonis (Krøyer 1837)) is an ectoparasitic copepod which represents a major pathogen of wild and farmed salmonid fishes in the marine environment. In order to facilitate research on this ecologically and economically important parasite, a hatchery and culturing system permitting the c...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2009.08.009
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND/AIMS:The aim of this study was to determine the prevalence and significance of intestinal protozoa, specially Blastocystis spp., and to perform PCR-based subtype classification for understanding the importance of Blastocystis spp. in the pathogenesis of gastrointestinal disorders in post-traumatic splenectom...
journal_title:Parasitology international
pub_type: 杂志文章
doi:10.1016/j.parint.2015.12.004
更新日期:2016-12-01 00:00:00