Abstract：
:We have proposed a mathematical model for the transmission of Plasmodium vivax malaria quantitatively, which is adjusted to the infected region, Guadalcanal, in the Solomon Islands. The simulation of a transmission model will be instrumental in planning the malaria control strategy. A characteristic of the life cycle of P. vivax is that a sporozoite injected into the blood stream by a mosquito bite may sometimes stay in a hepatocyte as a hypnozoite. Therefore, we have incorporated a phenomenon of renewed infections caused by a relapse into the transmission model. Also through the simulations we have attempted to evaluate the decline in prevalence caused by the programs of selective mass drug administration (MDA) and vector control such as the distribution of permethrin-treated bednets. The simulations have indicated that the concentrated repetition of MDA at 1-week intervals would reduce the prevalence of vivax malaria swiftly in the beginning and would keep the parasite rate below 1% for a few years but the prevalence would increase thereafter. In contrast, the parasite rate would remain below 1% for a long time if a trial of 1 or 2 times MDA is accompanied with some reduction of the vectorial capacity by the enforcement of vector control. In any case, it is important to beware of relapse cases because even after the execution of MDA it takes a long time to decrease the proportion of hypnozoite carriers.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Ishikawa H,Ishii A,Nagai N,Ohmae H,Harada M,Suguri S,Leafasia Jdoi
10.1016/s1383-5769(02)00084-3subject
Has Abstractpub_date
2003-03-01 00:00:00pages
81-93issue
1eissn
1383-5769issn
1873-0329pii
S1383576902000843journal_volume
52pub_type
杂志文章abstract：:The liver fluke, Opisthorchis viverrini, causes serious public-health problems in the Lower Mekong Basin. This study aimed to clarify whether O. viverrini populations may be genetically divided into sub-specific taxa. We collected 6 populations of O. viverrini from different places in Cambodia, Lao PDR, and Thailand, ...
journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
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journal_title：Parasitology international
pub_type： 杂志文章
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更新日期：2015-02-01 00:00:00
