Abstract：
:The clinical features of neurocysticercosis (NCC) largely depend on the number, type, size, localization and stage of development of cysticerci, as well as on the host immune response against the parasite. Seizures are widely reported to be the most common symptom, occurring in 70-90% of patients, while NCC is considered to be the main cause of late-onset epilepsy in endemic areas. When cysticerci lodge within the ventricular system, life-threatening acute intracranial hypertension secondary to hydrocephalus may develop. Cysts in the subarachnoid space may invade the Sylvian fissure and grow to large sizes (giant cysts) causing intracranial hypertension with hemiparesis, partial seizures or other focal neurological signs. Racemose cysts in the basal cisterns can cause an intense inflammatory reaction, fibrosis and progressive thickening of the leptomeninges at the base of the brain. In approximately 60% of the cases, there is an obstruction of the cerebrospinal fluid (CSF) circulation, resulting in hydrocephalus and intracranial hypertension. When hydrocephalus secondary to cysticercotic meningitis is present, the mortality rate is high (50%) and most patients die within 2 years after CSF shunting. Therefore, ventricular and basal cisternal locations are considered to be malignant forms of NCC. The diagnosis of NCC is based upon neuroimaging studies, laboratory analysis of the CSF and antibody detection in the serum. Nowadays, albendazole is considered the medication of choice for the therapy of NCC. Its main use is for symptomatic patients showing multiple viable brain parenchymal cysticerci.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Takayanagui OM,Odashima NSdoi
10.1016/j.parint.2005.11.016subject
Has Abstractpub_date
2006-01-01 00:00:00pages
S111-5eissn
1383-5769issn
1873-0329pii
S1383-5769(05)00120-0journal_volume
55 Supplpub_type
杂志文章,评审abstract：BACKGROUND/AIMS:The aim of this study was to determine the prevalence and significance of intestinal protozoa, specially Blastocystis spp., and to perform PCR-based subtype classification for understanding the importance of Blastocystis spp. in the pathogenesis of gastrointestinal disorders in post-traumatic splenectom...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.12.004
更新日期：2016-12-01 00:00:00
abstract：:The procyclic form of Trypanosoma brucei expresses procyclin surface glycoproteins with unusual glycosylphosphatidylinositol-anchor side chain structures that contain branched N-acetyllactosamine and lacto-N-biose units. The glycosyltransferase TbGT8 is involved in the synthesis of the branched side chain through its ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2014.01.007
更新日期：2014-06-01 00:00:00
abstract：:A cat excreting Echinococcus multilocularis eggs was recently identified in Hokkaido, representing the first such observation in Japan. The cat was raised free-range and frequently ate rodents. Fecal egg examination revealed eggs of taeniids (EPG: 440) and Spirometra spp. (EPG: >1000). PCR targeting part of the mitoch...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2008.07.001
更新日期：2008-12-01 00:00:00
abstract：:It has been reported that three human Taenia species are distributed in Indonesia: Taenia solium, Taenia asiatica and Taenia saginata. T. asiatica is well known in North Sumatra, especially on Samosir island in Lake Toba. T. solium and T. saginata are known from Bali. T. solium is most serious public health issue in P...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2005.11.024
更新日期：2006-01-01 00:00:00
abstract：:Strongyloides stercoralis is a parasitic nematode and a major pathogen responsible for human strongyloidiasis. The presence of this species in the dog population has led to an interest in studying the phylogenetic relationships among Strongyloides spp. in carnivore hosts. In the present study, Strongyloides spp. from ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102151
更新日期：2020-10-01 00:00:00
abstract：:We have proposed a mathematical model for the transmission of Plasmodium vivax malaria quantitatively, which is adjusted to the infected region, Guadalcanal, in the Solomon Islands. The simulation of a transmission model will be instrumental in planning the malaria control strategy. A characteristic of the life cycle ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(02)00084-3
更新日期：2003-03-01 00:00:00
abstract：:Malaria is caused by five species of Plasmodium in humans. Microscopy is currently used for pathogen detection, requiring considerable training and technical expertise as the parasites are often difficult to differentiate morphologically. Rapid diagnostic tests are as reliable as microscopy and offer faster diagnoses ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2018.01.005
更新日期：2018-06-01 00:00:00
abstract：:"Below is an essay by Prof. Tanabe originally written in Japanese. It gives an insight to Prof. Tanabe's inquiring mind and his approach to science. He also seek, as always, to inspire and nudge the young to scientific discovery". ...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2014.11.010
更新日期：2015-06-01 00:00:00
abstract：:The discovery of new compounds active against Toxoplasma gondii is extremely important due to the severe disease caused by this pathogen in immunocompromised hosts and to congenital infection. Type II fatty acid biosynthesis has shown to be a promising target for drug intervention in toxoplasmosis. Here we describe th...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.08.004
更新日期：2009-12-01 00:00:00
abstract：:Plants rich in condensed tannins are an alternative to chemical anthelmintics to control gastrointestinal nematodes (GINs) in ruminants. Previous functional studies have shown that sainfoin extracts affect the two forms of infective larvae (L3), ensheathed and exsheathed. However, the mechanisms of action remain unkno...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2010.09.011
更新日期：2011-12-01 00:00:00
abstract：:Gyrodactylus medaka n. sp. (Monogenea: Gyrodactylidae) is described from the skin, fins, and gills of medaka Oryzias latipes (Beloniformes: Adrianichthyidae) from Japan. This new species was collected from wild medaka in Hiroshima, Aichi, Saga, and Kumamoto prefectures, and laboratory-reared medaka in Chiba and Aichi ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2018.06.010
更新日期：2018-10-01 00:00:00
abstract：:Malaria is a disease caused by Plasmodium parasites that affects hundreds of millions of people. Plasmodium proteases are involved in invasion, erythrocyte egress and degradation of host proteins. Falcipains are well-studied cysteine peptidases located in P. falciparum food vacuoles that participate in hemoglobin degr...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2017.12.005
更新日期：2018-04-01 00:00:00
abstract：:The occurrence of parasitic copepods of the family Caligidae on wild and cultured marine fishes from Chamela Bay, on the Pacific coast of Mexico, is reported. A total of 16 species of Caligus and 1 species of Lepeophtheirus were found on 19 wild fish species. The description of Caligus chamelensis n. sp. parasitizing ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2013.09.005
更新日期：2014-02-01 00:00:00
abstract：:The liver fluke, Opisthorchis viverrini, causes serious public-health problems in the Lower Mekong Basin. This study aimed to clarify whether O. viverrini populations may be genetically divided into sub-specific taxa. We collected 6 populations of O. viverrini from different places in Cambodia, Lao PDR, and Thailand, ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2010.02.009
更新日期：2010-06-01 00:00:00
abstract：:A survey was carried out to investigate the occurrence of Sarcocystis infection in the loin (Musculus longissimus) of Japanese and imported beef. In all, the muscle tissue of 482 samples were examined by histological method. The prevalence of Sarcocystis unspecified species cysts was lower in Japanese beef (total 6.31...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(98)00041-5
更新日期：1999-03-01 00:00:00
abstract：:The effects of praziquantel and artesunate on the tegument of adult Schistosoma mekongi harboured in mice were compared using scanning electron microscopy (SEM). Forty-two mice infected with S. mekongi for 49 days were treated intragastrically with either 300 mg/kg praziquantel or 300 mg/kg artesunate. Mice were sacri...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2005.04.001
更新日期：2005-09-01 00:00:00
abstract：:The anti-Trichomonas vaginalis activity of Hypericum polyanthemum extract obtained by supercritical fluid extraction (50°C, 150bar) and the chemical compounds isolated and purified from this extract (benzopyrans HP1, HP2, HP3, and phloroglucinol derivative uliginosin B) were assessed. All samples had anti-T. vaginalis...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2012.10.006
更新日期：2013-04-01 00:00:00
abstract：:In Shiqu County of the Qinghai-Tibet plateau, many wild and domestic mammals are involved in the transmission cycles of Echinococcus spp. Echinococcus multilocularis and Echinococcus granulosus genotype G1 (sheep strain) are sympatrically distributed in the plateau. In 1995, we identified a unique strobilate stage of ...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/j.parint.2005.11.035
更新日期：2006-01-01 00:00:00
abstract：:Giardia intestinalis (G. intestinalis) is a flagellate parasite which has been considered the most common protozoan infecting human. Molecular techniques are of great value in studying the taxonomy, the zoonotic potential of animal isolates and the correlation between the genetic variability of the parasite and the ra...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.09.006
更新日期：2011-12-01 00:00:00
abstract：:Granuloma modulation induced by antigen is an attractive model for vaccination studies of experimental schistosomiasis to test the effect of anti-pathology vaccine. We describe here an immunization procedure with culture derived macrophages-pulsed PIII, a known anionic antigen purified from S. mansoni adult worm, invo...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(02)00031-4
更新日期：2002-09-01 00:00:00
abstract：:The asexual blood stages of the Plasmodium falciparum parasite are responsible for inducing the clinical symptoms and the most severe presentations of malaria infection that causes frequent mortality and morbidity in tropical and subtropical areas of the world, making the blood stages of infection a key target of new ...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2018.05.012
更新日期：2018-10-01 00:00:00
abstract：:The accurate characterization of Schistosoma japonicum has important implications for analyzing genetic variation and would provide basic data for disease control. Previous studies using proteins, coding sequences, and especially antigen-coding genes showed lower genetic variation among S. japonicum isolates from main...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2011.01.008
更新日期：2011-06-01 00:00:00
abstract：:A case of Acanthocephala infection in a 5-year-old female rehabilitated and released black-bellied pangolin (Phataginus tetradactyla), which was part of a post-release monitoring program of a pangolin research operation in the Central African Republic, is described. This represents the first report of Acanthocephala i...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2020.102182
更新日期：2021-02-01 00:00:00
abstract：:Except for imported cases, we have had no new Schistosoma japonicum infection in Japan since 1977. But there are still two habitats of the intermediate snail host: Oncomelania nosophora in the previous endemic areas of Kofu Basin and Obitsu. O. nosophora from Kofu Basin and Obitsu are susceptible to Chinese and Philip...
journal_title：Parasitology international
pub_type： 杂志文章,评审
doi：10.1016/s1383-5769(03)00058-8
更新日期：2003-12-01 00:00:00
abstract：:Several Sarcocystis spp. have carnivores as definitive host and sarcocysts are common in muscles of herbivores (intermediate host). However, sarcocysts have been found in muscles of wild and domestic carnivores suggesting they are intermediate host for some Sarcocystis spp. Here, we report mature sarcocysts in the mus...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2017.01.021
更新日期：2017-06-01 00:00:00
abstract：:Septin4 (Sept4) belongs to Septin family and may be involved in apoptosis, vesicle trafficking and other cell processes. In this study, we attempted to investigate the effect of Sept4 in hepatic fibrosis induced by Schistosoma japonicum. ICR mice infected with S. japonicum for 12weeks were treated with PBS, Ad-ctr and...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.07.002
更新日期：2015-12-01 00:00:00
abstract：:The antimalarial activity of the hot-water extract of Hydrangea macrophylla var. Otaksa leaves was evaluated against Plasmodium yoelii 17XL in mice. Non-treated control mice died from 6 to 7 days after infection, but mice treated with the leaf extract survived during the experiment. Mice given the extract orally showe...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/s1383-5769(00)00069-6
更新日期：2001-03-01 00:00:00
abstract：:The parasite Giardia intestinalis undergoes a differentiation process that allows it to infect its mammal host. That process is excystation. We examined the importance of protein phosphorylation during the passage from cyst to trophozoite. Cysts obtained from patients with giardiasis were excysted in vitro and the sol...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2009.10.005
更新日期：2010-03-01 00:00:00
abstract：:The protozoan Trypanosoma cruzi is a parasite exposed to several environmental stressors inside its invertebrate and vertebrate hosts. Although stress conditions are involved in its differentiation processes, little information is available about the stress response proteins engaged in these activities. This work repo...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2017.10.009
更新日期：2018-04-01 00:00:00
abstract：:Toxoplasmosis is a concern in both human and veterinary medicine, and the consumption of undercooked meat infected with Toxoplasma gondii is a major risk factor in human infection. Establishing the prevalence of the parasite in food-producing livestock is essential to reduce the risk of human infection. This study aim...
journal_title：Parasitology international
pub_type： 杂志文章
doi：10.1016/j.parint.2015.07.004
更新日期：2015-12-01 00:00:00
