Fast calculation of 3D radiofrequency ablation zone based on a closed-form solution of heat conduction equation fitted by ex vivo measurements.

abstract：:Fluorescence diffuse optical tomography (fDOT) provides 3D images of fluorescence distributions in biological tissue, which represent molecular and cellular processes. The image reconstruction problem is highly ill-posed and requires regularisation techniques to stabilise and find meaningful solutions. Quadratic regul...

journal_title：Physics in medicine and biology

authors： Correia T,Koch M,Ale A,Ntziachristos V,Arridge S

更新日期：2016-02-21 00:00:00

abstract：:An X-ray technique has been developed to enable reproducible and quantitative data to be obtained from radiographs taken by a diagnostic X-ray machine. Careful attention has been paid to the alignment of the specimen and the diagnostic tube and to operating conditions. The choice of X-ray spectrum is described togethe...

journal_title：Physics in medicine and biology

authors： King SD

更新日期：1977-07-01 00:00:00

abstract：:The use of deformable image registration methods in the context of adaptive radiotherapy leads to uncertainties in the simulation of the administered dose distributions during the treatment course. Evaluation of these methods is a prerequisite to decide if a plan adaptation will improve the individual treatment. Curre...

journal_title：Physics in medicine and biology

authors： Teske H,Bartelheimer K,Meis J,Bendl R,Stoiber EM,Giske K

更新日期：2017-06-21 00:00:00

abstract：:Grating-based x-ray phase-contrast imaging provides three simultaneous image channels originating from a single image acquisition. While the phase signal provides direct access to the electron density in tomography, there is additional information on sub-resolutional structural information which is called dark-field s...

journal_title：Physics in medicine and biology

authors： Braig EM,Pfeiffer D,Willner M,Sellerer T,Taphorn K,Petrich C,Scholz J,Petzold L,Birnbacher L,Dierolf M,Pfeiffer F,Herzen J

更新日期：2020-09-18 00:00:00

abstract：:Radiation therapy is an image-guided process whose success critically depends on the imaging modality used for treatment planning and the level of integration of the available imaging information. In this work, we establish a dose optimization framework for incorporating metabolic information from functional imaging m...

journal_title：Physics in medicine and biology

authors： Xing L,Cotrutz C,Hunjan S,Boyer AL,Adalsteinsson E,Spielman D

更新日期：2002-10-21 00:00:00

abstract：:Few quantitative data are available on the kinetics of polymerization reactions in polymer gel (PAG) dosimeters and their long-term stability. Post-irradiation polymerization reactions have been found to continue for several weeks, posing questions regarding dosimeter stability and its achievement. In this paper we re...

journal_title：Physics in medicine and biology

authors： McJury M,Oldham M,Leach MO,Webb S

更新日期：1999-08-01 00:00:00

abstract：:The theory of task-based assessment of image quality is reviewed in the context of imaging with ionizing radiation, and objective figures of merit (FOMs) for image quality are summarized. The variation of the FOMs with the task, the observer and especially with the mean number of photons recorded in the image is discu...

journal_title：Physics in medicine and biology

authors： Barrett HH,Myers KJ,Hoeschen C,Kupinski MA,Little MP

更新日期：2015-01-21 00:00:00

abstract：:A number of heating sources are available for minimally invasive thermal therapy of tumours. The purpose of this work was to compare, theoretically, the heating characteristics of interstitial microwave, laser and ultrasound sources in three tissue sites: breast, brain and liver. Using a numerical method, the heating ...

journal_title：Physics in medicine and biology

authors： Skinner MG,Iizuka MN,Kolios MC,Sherar MD

更新日期：1998-12-01 00:00:00

abstract：:This paper reports an inverse arc-modulated radiation therapy planning technique based on linear models. It is implemented with a two-step procedure. First, fluence maps for 36 fixed-gantry beams are generated using a linear model-based intensity-modulated radiation therapy (IMRT) optimization algorithm. The 2D fluenc...

journal_title：Physics in medicine and biology

authors： Zhu X,Thongphiew D,McMahon R,Li T,Chankong V,Yin FF,Wu QJ

更新日期：2010-07-07 00:00:00

abstract：:The diagnosis of hepatocellular carcinoma (HCC) usually occurs at late stages in the disease when there are few effective treatment options. The measurement of the concentration of tumour markers in the serum of patients is a complementary tool frequently used for the interpretation of diagnostic imaging results. It i...

journal_title：Physics in medicine and biology

authors： Elshemey WM,Desouky OS,Mohammed MS,Elsayed AA,el-Houseini ME

更新日期：2003-09-07 00:00:00

abstract：:Accurate real-time prediction of respiratory motion is desirable for effective motion management in radiotherapy for lung tumor targets. Recently, nonparametric methods have been developed and their efficacy in predicting one-dimensional respiratory-type motion has been demonstrated. To exploit the correlation among v...

journal_title：Physics in medicine and biology

authors： Ruan D,Keall P

更新日期：2010-06-07 00:00:00

abstract：:In response to the recognized fragility of reactor-produced (99)Mo supply, direct production of (99m)Tc via (100)Mo(p,2n)(99m)Tc reaction using medical cyclotrons has been investigated. However, due to the existence of other Molybdenum (Mo) isotopes in the target, in parallel with (99m)Tc, other technetium (Tc) radioa...

journal_title：Physics in medicine and biology

authors： Hou X,Tanguay J,Buckley K,Schaffer P,Bénard F,Ruth TJ,Celler A

更新日期：2016-01-21 00:00:00

abstract：:The poor agreement in the photon calibrations of tissue-equivalent ionisation chambers between different participants in two major neutron dosimetry intercomparisons is noted. The methods of converting measurements made with a calibrated secondary standard exposure meter to the absorbed dose in the wall of a tissue-eq...

journal_title：Physics in medicine and biology

authors： Williams JR,Greening JR

更新日期：1980-03-01 00:00:00

abstract：:To increase the scanning speed of cone-beam CT, a scanning configuration with three pairs of x-ray sources and panel detectors was proposed. In this paper, we apply the M-line-based backprojected filtration algorithm to this scanning configuration and propose a fast implementation for this algorithm. Compared with exi...

journal_title：Physics in medicine and biology

authors： Zhao Y,Zhu Y,Zhang P

更新日期：2010-12-07 00:00:00

abstract：:Absorbed dose values were determined under the reference conditions in a phantom irradiated by high-energy photon beams with quality varying between 60Co gamma rays and 25 MV X-rays, using four commonly employed types of ionisation chamber. The ionisation chamber readings were converted to absorbed dose values applyin...

journal_title：Physics in medicine and biology

authors： Mijnheer BJ,Wittkämper FW

更新日期：1986-04-01 00:00:00

abstract：:Microbeam radiation therapy (MRT) is a pre-clinical, spatially-fractionated treatment modality noted for its ability to achieve a large differential response between normal and tumoral tissues. In the present study, TOPAS Monte Carlo (MC) simulations were used to optimize the design of a compact, affordable multi-slit...

journal_title：Physics in medicine and biology

authors： Esplen NM,Chergui L,Johnstone CD,Bazalova-Carter M

更新日期：2018-08-29 00:00:00

abstract：:In this note a technique is described for direct aperture optimization of components deliverable by a variable aperture collimator (VAC) for intensity-modulated radiation therapy. The first key result found was that, provided a large number of VAC components were selected for optimization, the resulting fluence profil...

journal_title：Physics in medicine and biology

authors： Webb S

更新日期：2004-03-07 00:00:00

abstract：:Radiotherapy calculations often involve complex geometries such as interfaces between materials of vastly differing atomic number, such as lung, bone and/or air interfaces. Monte Carlo methods have been used to calculate accurately the perturbation effects of the interfaces. However, these methods can be computational...

journal_title：Physics in medicine and biology

authors： Gifford KA,Horton JL,Wareing TA,Failla G,Mourtada F

更新日期：2006-05-07 00:00:00

abstract：:A 3D anatomical computational model is developed to assess thermal effects due to exposure to the electromagnetic field required to power a new investigational active implantable microvalve for the treatment of glaucoma. Such a device, located in the temporal superior eye quadrant, produces a filtering bleb, which is ...

journal_title：Physics in medicine and biology

authors： Schaumburg F,Guarnieri FA

更新日期：2017-05-07 00:00:00

abstract：:Plutonium-239 and americium-241 were administered to adult hamsters in various chemical forms and their absorption from the gut was measured. The results have been compared with published data on other species in order to derive values for the estimated absorption of these actinides in man. On the basis of current kno...

journal_title：Physics in medicine and biology

authors： Stather JW,Harrison JD,Rodwell P,David AJ

更新日期：1979-03-01 00:00:00

abstract：:The quality of thorax and pelvis transmission scans and therefore of attenuation correction in PET depends on patient thickness and transmission rod source strength. The purpose of the present study was to assess the feasibility of using count-based transmission scans, thereby guaranteeing more consistent image qualit...

journal_title：Physics in medicine and biology

authors： Boellaard R,van Lingen A,van Balen SC,Lammertsma AA

更新日期：2004-02-21 00:00:00

abstract：:Compact gamma cameras with a square-shaped monolithic scintillator crystal and an array of silicon photomultipliers (SiPMs) are actively being developed for applications in areas such as small animal imaging, cancer diagnostics and radiotracer guided surgery. Statistical methods of position reconstruction, which are p...

journal_title：Physics in medicine and biology

authors： Morozov A,Alves F,Marcos J,Martins R,Pereira L,Solovov V,Chepel V

更新日期：2017-05-07 00:00:00

abstract：:This paper presents two 4D mathematical observer models for the detection of motion defects in 4D gated medical images. Their performance was compared with results from human observers in detecting a regional motion abnormality in simulated 4D gated myocardial perfusion (MP) SPECT images. The first 4D mathematical obs...

journal_title：Physics in medicine and biology

authors： Lee TS,Frey EC,Tsui BM

更新日期：2015-04-07 00:00:00

abstract：:The purpose of this study was to derive a complete set of correction and perturbation factors for output factors (OF) and dose profiles. Modern small field detectors were investigated including a plastic scintillator (Exradin W1, SI), a liquid ionization chamber (microLion 31018, PTW), an unshielded diode (Exradin D1V...

journal_title：Physics in medicine and biology

authors： Papaconstadopoulos P,Tessier F,Seuntjens J

更新日期：2014-10-07 00:00:00

abstract：:For proton therapy, an accurate conversion of CT HU to relative stopping power (RSP) is essential. Validation of the conversion based on real tissue samples is more direct than the current practice solely based on tissue substitutes and can potentially address variations over the population. Based on a novel dose exti...

journal_title：Physics in medicine and biology

authors： Zhang R,Baer E,Jee KW,Sharp GC,Flanz J,Lu HM

更新日期：2017-06-23 00:00:00

abstract：:Dosimetry of proton beams is generally evaluated in liquid water, or alternatively in solid phantoms via water equivalent ratios (WER). WER is defined as the ratio of proton range in liquid water to that in a phantom of certain material. Presently, WER is not available in the literature neither for a wide range of ene...

journal_title：Physics in medicine and biology

authors： Safigholi H,Song WY

更新日期：2018-07-27 00:00:00

abstract：:Over the course of radiation therapy, a patient's anatomy may change substantially. The relatively recent addition of frequent in-room imaging to assist with patient localization has provided a database of images that may be used to recalculate dose distributions for adaptive radiotherapy purposes. The TomoTherapy Hi-...

journal_title：Physics in medicine and biology

authors： Pukala J,Meeks SL,Bova FJ,Langen KM

更新日期：2011-12-21 00:00:00

abstract：:Ultrasound-based elastography including strain elastography, acoustic radiation force impulse (ARFI) imaging, point shear wave elastography and supersonic shear imaging (SSI) have been used to differentiate breast tumors among other clinical applications. The objective of this study is to extend a previously published...

journal_title：Physics in medicine and biology

authors： Wang Y,Peng B,Jiang J

更新日期：2017-03-07 00:00:00

abstract：:Single monochromator charge-coupled device (CCD) array spectroradiometers have the advantage of ease of use and speed compared with double grating instruments. Their inherently inferior stray-light rejection, however, can critically affect their accuracy in phototherapy and research-related dosimetry applications. Thi...

journal_title：Physics in medicine and biology

authors： Coleman A,Sarkany R,Walker S

更新日期：2008-09-21 00:00:00

abstract：:Magnetic Resonance Electrical Impedance Tomography (MREIT) is an MRI method that enables mapping of internal conductivity and/or current density via measurements of magnetic flux density signals. The MREIT measures only the z-component of the induced magnetic flux density B = (Bx, By, Bz) by external current injection...

journal_title：Physics in medicine and biology

authors： Jeong WC,Chauhan M,Sajib SZ,Kim HJ,Serša I,Kwon OI,Woo EJ

更新日期：2014-09-07 00:00:00