Direct aperture optimization for a variable aperture collimator for intensity-modulated radiation therapy.

abstract：:Cylindrical ionization chambers with varying radii have been used to determine the displacement effect at distances between 10 mm and 40 mm from 60Co and 192Ir brachytherapy sources. Agreement with published values of the displacement factor for external 60Co beams is obtained. The shift between the centre of the ioni...

journal_title：Physics in medicine and biology

authors： Tölli H,Johansson KA

更新日期：1993-10-01 00:00:00

abstract：:Monte Carlo simulation of beam modifiers such as physical wedges and compensating filters has been performed with a rectilinear voxel geometry module. A modified version of the EGS4/DOSXYZ code has been developed for this purpose. The new implementations have been validated against the BEAM Monte Carlo code using its ...

journal_title：Physics in medicine and biology

authors： Spezi E,Lewis DG,Smith CW

更新日期：2001-11-01 00:00:00

abstract：:Measurements of lung nodule volume with multi-detector computed tomography (MDCT) have been shown to be more accurate and precise compared to conventional lower dimensional measurements. Quantifying the size of lesions is potentially more difficult when the object-to-background contrast is low as with lesions in the l...

journal_title：Physics in medicine and biology

authors： Li Q,Gavrielides MA,Zeng R,Myers KJ,Sahiner B,Petrick N

更新日期：2015-01-21 00:00:00

abstract：:The aim of this study was to evaluate angiogenic compositions and tumour response in the course of neoadjuvant chemotherapy in patients with locally advanced breast cancer (LABC) using dynamic contrast-enhanced (DCE) MRI. Thirteen patients with LABC underwent serial DCE MRI during the course of chemotherapy. DCE MRI w...

journal_title：Physics in medicine and biology

authors： Chang YC,Huang CS,Liu YJ,Chen JH,Lu YS,Tseng WY

更新日期：2004-08-21 00:00:00

abstract：:A radiofrequency and field-gradient pulse sequence is presented permitting the non-invasive, volume-selective and spectroscopically resolved determination of incoherent transport parameters with the aid of an NMR field-gradient method. With proton NMR, diffusion or (quasi-incoherent) perfusion coefficients as low as 1...

journal_title：Physics in medicine and biology

authors： Klammler F,Kimmich R

更新日期：1990-01-01 00:00:00

abstract：:In this study we present a three-dimensional (3D) reconstruction algorithm for magneto-acoustic tomography with magnetic induction (MAT-MI) based on the characteristics of the ultrasound transducer. The algorithm is investigated to solve the blur problem of the MAT-MI acoustic source image, which is caused by the ultr...

journal_title：Physics in medicine and biology

authors： Ma R,Zhou X,Zhang S,Yin T,Liu Z

更新日期：2016-12-21 00:00:00

abstract：:The results of optimization of inverse treatment plans depend on a choice of the objective function. Even when the optimal solution for a given cost function can be obtained, a better solution may exist for a given clinical scenario and it could be obtained with a revised objective function. In the approach presented ...

journal_title：Physics in medicine and biology

authors： Bednarz G,Michalski D,Anne PR,Valicenti RK

更新日期：2004-06-21 00:00:00

abstract：:A method using both patient geometric and dosimetric information was proposed to predict dose-volume histograms (DVHs) of organs at risk (OARs) for a nasopharyngeal cancer (NPC) intensity-modulated radiation therapy (IMRT) plan. A total of 106 nine-field IMRT NPC plans were used in this study. Twenty-six plans were ra...

journal_title：Physics in medicine and biology

authors： Jiao SX,Chen LX,Zhu JH,Wang ML,Liu XW

更新日期：2019-12-05 00:00:00

abstract：:Reference dosimetry in the presence of a strong magnetic field is challenging. Ionisation chambers have shown to be strongly affected by magnetic fields. There is a need for robust and stable detectors in MRI-guided radiotherapy (MRIgRT). This study investigates the behaviour of the alanine dosimeter in magnetic field...

journal_title：Physics in medicine and biology

authors： Billas I,Bouchard H,Oelfke U,Shipley D,Gouldstone C,Duane S

更新日期：2020-06-03 00:00:00

abstract：:Evaluation of the radioisotopic purity of technetium-99m (99mTc) produced in GBq amounts by proton bombardment of enriched molibdenum-100 (100Mo) metallic targets at low proton energies (i.e. within 15-20 MeV) is conducted. This energy range was chosen since it is easily achievable by many conventional medical cyclotr...

journal_title：Physics in medicine and biology

authors： Uzunov NM,Melendez-Alafort L,Bello M,Cicoria G,Zagni F,De Nardo L,Selva A,Mou L,Rossi-Alvarez C,Pupillo G,Di Domenico G,Uccelli L,Boschi A,Groppi F,Salvini A,Taibi A,Duatti A,Martini P,Pasquali M,Loriggiola M,Mare

更新日期：2018-09-19 00:00:00

abstract：:Magnetic resonance and ultrasound elastography techniques are now important tools for staging high-grade fibrosis in patients with chronic liver disease. However, uncertainty remains about the effects of simple accumulation of fat (steatosis) and inflammation (steatohepatitis) on the parameters that can be measured us...

journal_title：Physics in medicine and biology

authors： Parker KJ,Ormachea J,Drage MG,Kim H,Hah Z

更新日期：2018-05-17 00:00:00

abstract：:Radiochromic leuco crystal violet (LCV) micelle gel dosimeters are promising three-dimensional radiation dosimeters because of their spatial stability and suitability for optical readout. The effects of surfactant type and surfactant concentration on dose sensitivity of LCV micelle gels are tested, demonstrating that ...

journal_title：Physics in medicine and biology

authors： Nasr AT,Alexander K,Schreiner LJ,McAuley KB

更新日期：2015-06-21 00:00:00

abstract：:Ultra-wideband (UWB) electromagnetic pulses of nanosecond duration, or nanopulses, have recently been approved by the Federal Communications Commission for a number of different applications. They are also being explored for applications in biotechnology and medicine. The simulation of the propagation of a nanopulse t...

journal_title：Physics in medicine and biology

authors： Simicevic N

更新日期：2005-11-07 00:00:00

abstract：:Lymphedema is a common condition involving an abnormal accumulation of lymphatic fluid in the interstitial space that causes swelling, most often in the arm(s) and leg(s). Lymphedema is a significant lifelong concern that can be congenital or develop following cancer treatment or cancer metastasis. Common methods of e...

journal_title：Physics in medicine and biology

authors： Righetti R,Garra BS,Mobbs LM,Kraemer-Chant CM,Ophir J,Krouskop TA

更新日期：2007-11-07 00:00:00

abstract：:All dosimetry protocols recommend the use of plane-parallel chambers for dose determination in electron beams with energies below 10-15 MeV. The protocols have assumed chamber perturbation effects to be negligible. The new AAPM Protocol (TG39) includes a cavity replacement factor prepl that differs from unity for some...

journal_title：Physics in medicine and biology

authors： Nilsson B,Montelius A,Andreo P

更新日期：1996-04-01 00:00:00

abstract：:The total ionisation produced by ions stopped in nitrogen, methane and carbon dioxide has been measured in the energy range 25-375 keV using a chamber described previously. The chamber was operated alternately as a proportional counter and as an ionisation chamber to measure respectively the particle rate and the tota...

journal_title：Physics in medicine and biology

authors： Nguyen VD,Chemtob M,Chary J,Posny F,Parmentier N

更新日期：1980-05-01 00:00:00

abstract：:Factors affecting the accuracy of the in vivo measurement of cutaneous pigments and blood oxygenation by reflectance spectrophotometry have been examined. It was found that stray light, the amounts of haemoglobin and melanin, and the level of blood oxygenation all contributed to the measured reflectance and had to be ...

journal_title：Physics in medicine and biology

authors： Hajizadeh-Saffar M,Feather JW,Dawson JB

更新日期：1990-09-01 00:00:00

abstract：:Peripheral neural stimulation is a major problem in current gradient coil designs. Induced current problems in patients relate directly to gradient strength and modulation frequency. Present designs of gradient coil tend to limit ultra-high-speed imaging methods such as echo-planar imaging (EPI) and echo-volumar imagi...

journal_title：Physics in medicine and biology

authors： Mansfield P,Haywood B

更新日期：2008-04-07 00:00:00

abstract：:All available imaging devices in nuclear medicine have finite energy resolution. This leads to inclusion of scattered radiation, which in turn degrades the image quality. Different scatter correction schemes therefore try to eliminate the effect of scattered radiation. On the other hand, improvement of the camera's in...

journal_title：Physics in medicine and biology

authors： Wirth V

更新日期：1989-01-01 00:00:00

abstract：:Multileaf collimator (MLC) calibration and quality control is a time-consuming procedure typically involving the processing, scanning and analysis of films to measure leaf and collimator positions. Faster and more reliable calibration procedures are required for these tasks, especially with the introduction of intensi...

journal_title：Physics in medicine and biology

authors： Baker SJ,Budgell GJ,MacKay RI

更新日期：2005-04-07 00:00:00

abstract：:Planning of radiotherapy is often difficult due to restrictions on morphological images. New imaging techniques enable the integration of biological information into treatment planning and help to improve the detection of vital and aggressive tumour areas. This might improve clinical outcome. However, nowadays morphol...

journal_title：Physics in medicine and biology

authors： Neff T,Kiessling F,Brix G,Baudendistel K,Zechmann C,Giesel FL,Bendl R

更新日期：2005-09-07 00:00:00

abstract：:Most tissue characterization methods use RF data originating from backscattering processes in the insonified tissue. Characterization of the tissue of a thin layer (e.g., an artery wall) poses problems because of the small amount of data available. The tissue layer may be so thin that there are no RF data that are not...

journal_title：Physics in medicine and biology

authors： Linssen FM,Hoeks AP,Brands PJ

更新日期：1991-10-01 00:00:00

abstract：:Quantification of nuclear medicine image data is a prerequisite for personalized absorbed dose calculations and quantitative biodistribution studies. The spatial response of a detector is a governing factor affecting the accuracy of image quantification, and the aim of this work was to model this impact. To simulate s...

journal_title：Physics in medicine and biology

authors： Holstensson M,Partridge M,Buckley SE,Flux GD

更新日期：2010-03-21 00:00:00

abstract：:A novel transmission detector (IBA Dosimetry, Germany) developed as an IMRT quality assurance tool, intended for in vivo patient dose measurements, is studied here. The goal of this investigation is to use Monte Carlo techniques to characterize treatment beam parameters in the presence of the detector and to compare t...

journal_title：Physics in medicine and biology

authors： Asuni G,Jensen JM,McCurdy BM

更新日期：2011-02-21 00:00:00

abstract：:The enormous advances in the understanding of human anatomy, physiology and pathology in recent decades have led to ever-improving methods of disease prevention, diagnosis and treatment. Many of these achievements have been enabled, at least in part, by advances in ionizing radiation detectors. Radiology has been tran...

journal_title：Physics in medicine and biology

authors： Seco J,Clasie B,Partridge M

更新日期：2014-10-21 00:00:00

abstract：:A formalism is proposed for the estimation of mean glandular dose for breast tomosynthesis, which is a simple extension of the UK, European and IAEA protocols for dosimetry in conventional projection mammography. The formalism introduces t-factors for the calculation of breast dose from a single projection and T-facto...

journal_title：Physics in medicine and biology

authors： Dance DR,Young KC,van Engen RE

更新日期：2011-01-21 00:00:00

abstract：:Monte Carlo simulation was used to calculate correction factors for output factor (OF), percentage depth-dose (PDD), and off-axis ratio (OAR) measurements with the CyberKnife M6 System. These include the first such data for the InCise MLC. Simulated detectors include diodes, air-filled microchambers, a synthetic micro...

journal_title：Physics in medicine and biology

authors： Francescon P,Kilby W,Noll JM,Masi L,Satariano N,Russo S

更新日期：2017-02-07 00:00:00

abstract：:The measured attenuation correction technique is widely used in cardiac positron tomographic studies. However, the success of this technique is limited because of insufficient counting statistics achievable in practical transmission scan times, and of the scattered radiation in transmission measurement which leads to ...

journal_title：Physics in medicine and biology

authors： Yu SK,Nahmias C

更新日期：1996-10-01 00:00:00

abstract：:Simultaneous near-infrared spectroscopy (NIRS) and magnetic resonance imaging (MRI) were used to investigate the correlation between tumour vascular oxygenation and tissue oxygen tension dynamics in rat breast 13762NF tumours with respect to hyperoxic gas breathing. NIRS directly detected global variations in the oxyg...

journal_title：Physics in medicine and biology

authors： Xia M,Kodibagkar V,Liu H,Mason RP

更新日期：2006-01-07 00:00:00

abstract：:A dedicated small-animal x-ray micro computed tomography (micro-CT) system has been developed to screen laboratory small animals such as mice and rats. The micro-CT system consists of an indirect-detection flat-panel x-ray detector with a field-of-view of 120 x 120 mm2, a microfocus x-ray source, a rotational subject ...

journal_title：Physics in medicine and biology

authors： Lee SC,Kim HK,Chun IK,Cho MH,Lee SY,Cho MH

更新日期：2003-12-21 00:00:00