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In vitro susceptibility of Mycobacterium avium complex to antibacterial agents.

Abstract：

:In vitro agar dilution susceptibility studies were performed utilizing 20 isolates (24 against rifamycin) of Mycobacterium avium complex against several antimicrobial agents not routinely tested in the mycobacteriology laboratory. Thirteen strains were susceptible to gentamicin at 4 micrograms/ml, 20 to amikacin at 8 micrograms/ml, 18 to streptomycin at 8 micrograms/ml, 20 to kanamycin at 8 micrograms/ml, 20 to trimethoprim/sulfamethoxazole at 2 micrograms/ml, 12 to sulfisoxazole at 10 micrograms/ml, 14 to rifabutin at 1 microgram/ml. No activity was found with penicillin G, cephapirin, moxalactam, vancomycin, clindamycin, erythromycin, trimethoprim, or minocycline. This data suggests a potential use of trimethoprim/sulfamethoxazole, sulfisoxazole, amikacin, gentamicin, and kanamycin in the treatment of infections caused by this group of organisms.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Davis CE Jr,Carpenter JL,Trevino S,Koch J,Ognibene AJ

doi

10.1016/0732-8893(87)90165-9

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

149-55

issue

3

eissn

0732-8893

issn

1879-0070

pii

0732-8893(87)90165-9

journal_volume

8

pub_type

杂志文章

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