White matter microstructural changes in pure Alzheimer's disease and subcortical vascular dementia.

abstract：:This study is aimed at assessing the prevalence and features of psychotic symptoms in a sample of 180 patients with Alzheimer's disease (AD). Sixty-four patients (35.5% of the sample) showed one or more psychotic symptoms. The presence of these symptoms correlated with the severity of the patients' cognitive impairmen...

journal_title：European journal of neurology

authors： Sala SD,Francescani A,Muggia S,Spinnler H

更新日期：1998-11-01 00:00:00

abstract：:Migraine is one of the most frequent disabling neurological conditions with a major impact on the patients' quality of life. To give evidence-based or expert recommendations for the different drug treatment procedures of the different migraine syndromes based on a literature search and an consensus in an expert panel....

journal_title：European journal of neurology

authors： Members of the task force:.,Evers S,Afra J,Frese A,Goadsby PJ,Linde M,May A,Sándor PS

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:Observational study to evaluate long-term effects of deep brain stimulation (DBS) of the globus pallidus internus (GPi) and the ventral intermediate thalamic nucleus (VIM) on patients with medically refractory myoclonus dystonia (MD). BACKGROUND:More recently, pallidal as well as thalamic DBS have been appli...

journal_title：European journal of neurology

authors： Krause P,Koch K,Gruber D,Kupsch A,Gharabaghi A,Schneider GH,Kühn AA

更新日期：2021-01-16 00:00:00

abstract：BACKGROUND:Cardiac (123) I-metaiodobenzylguanidine ((123) I-MIBG) uptake in patients with idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) is markedly reduced, as in Parkinson's disease (PD). METHODS:We performed (123) I-MIBG scintigrams on patients with iRBD and PD. After the initial (123) I-MIBG sc...

journal_title：European journal of neurology

authors： Miyamoto T,Miyamoto M,Iwanami M,Hirata K

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mutations in the PLA2G6 gene are causative of PLA2G6-associated neurodegeneration (PLAN), a spectrum of neurodegenerative conditions including infantile, childhood and adult onset forms. METHODS:Seventeen North African patients with a clinical suspicion of infantile-onset PLAN underwent clinical...

journal_title：European journal of neurology

authors： Romani M,Kraoua I,Micalizzi A,Klaa H,Benrhouma H,Drissi C,Turki I,Castellana S,Mazza T,Valente EM,Gouider-Khouja N

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Functional connectivity studies revealed alterations within thalamic, salience, and default mode networks in restless legs syndrome patients. METHODS:Eighty-two patients with restless legs syndrome (untreated, n = 30; on dopaminergic medication, n = 42; on alpha-2-delta ligands as mono- or polyt...

journal_title：European journal of neurology

authors： Tuovinen N,Stefani A,Mitterling T,Heidbreder A,Frauscher B,Gizewski ER,Poewe W,Högl B,Scherfler C

更新日期：2021-02-01 00:00:00

abstract：:The aim of this study was to compare the clinically based prevalence of myasthenia gravis (MG) with the prevalence of laboratory-confirmed cases. All patients with a diagnosis of MG living in Estonia as on 1 January 1997 were asked to participate in re-examination. The criteria for laboratory-supported MG were weaknes...

journal_title：European journal of neurology

authors： Oöpik M,Puksa L,Lüüs SM,Kaasik AE,Jakobsen J

更新日期：2008-03-01 00:00:00

abstract：:The authors report results of a retrospective pilot study showing a strong association between patients with stroke/TIA and the presence of circulating IgG and IgA antibodies to Chlamydia pneumoniae. These results support the hypothesis that chronic active or persistent infection may play a role in the mechanism of th...

journal_title：European journal of neurology

authors： Bucurescu G,Stieritz DD

更新日期：2003-07-01 00:00:00

abstract：:One of the main goals when treating spasticity is to relieve pain and improve function. Intramuscular injection of botulinum toxin type A (BTX-A) has gained widespread acceptance in the treatment of spastic cerebral palsy. Several studies have clearly shown the short-term functional benefit of BTX-A treatment. Informa...

journal_title：European journal of neurology

authors： Linder M,Schindler G,Michaelis U,Stein S,Kirschner J,Mall V,Berweck S,Korinthenberg R,Heinen F

更新日期：2001-11-01 00:00:00

abstract：:We examined the prevalence and correlates of apathy and irritability in a consecutive series of 101 patients with probable Alzheimer's disease (AD). Based on clinical criteria, 46 (46%) patients had apathy, and 13 (13%) patients had irritability. Apathy was significantly associated with more severe impairments in acti...

journal_title：European journal of neurology

authors： Starkstein SE,Migliorelli R,Manes F,Tesón A,Petracca G,Chemerinski E,Sabe L,Leiguarda R

更新日期：1995-12-01 00:00:00

abstract：:Registration of all hospitalized stroke patients is practiced in Sweden in order to assess care quality. Data in this register, Riks-Stroke (RS), may be biased due to incomplete registration. The purpose of this paper was to report changes in stroke outcome in relation to fluctuations in registration. Patients registe...

journal_title：European journal of neurology

authors： Appelros P,Samuelsson M,Karlsson-Tivenius S,Lokander M,Terént A

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Multiple mitochondrial DNA (mtDNA) deletions usually have a mendelian inheritance secondary to mutation in nuclear genes. One of these is the Twinkle gene whose mutation is responsible for autosomal dominant progressive external ophthalmoplegia (PEO). The number of reported cases with mainly myopathic sympto...

journal_title：European journal of neurology

authors： Martin-Negrier ML,Sole G,Jardel C,Vital C,Ferrer X,Vital A

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mutations in the glucocerebrosidase (GBA) gene have been implicated in the development of Parkinson's disease (PD). However, recent screenings for GBA mutations in PD subjects from different ethnic populations have yielded contradictory results. METHODS:We performed a case-control study to look ...

journal_title：European journal of neurology

authors： Hu FY,Xi J,Guo J,Yu LH,Liu L,He XH,Liu ZL,Zou XY,Xu YM

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although erenumab has demonstrated significant reduction in migraine frequency and improved quality of life in studies lasting 3 to 12 months, little is known about long-term therapy. METHODS:This study was an open-label, 5-year treatment phase following a 12-week, double-blind, placebo-controll...

journal_title：European journal of neurology

authors： Ashina M,Goadsby PJ,Reuter U,Silberstein S,Dodick DW,Xue F,Zhang F,Paiva da Silva Lima G,Cheng S,Mikol DD

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND AND PURPOSE:Antecedent surgery has been described to trigger Guillain-Barré syndrome (GBS), but its evidence is poor and based on case reports only. METHODS:We performed a retrospective analysis of 63 patients with GBS admitted to the University Hospital Basel and University Children's Hospital Basel from J...

journal_title：European journal of neurology

authors： Gensicke H,Datta AN,Dill P,Schindler C,Fischer D

更新日期：2012-09-01 00:00:00

abstract：:Multiple sclerosis (MS) is a T-cell-mediated autoimmune demyelinating disease of the central nervous system, associated with an altered cytokine network. We previously assayed peripheral blood T-lymphocyte binding for two prototypic cytokines, tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), and foun...

journal_title：European journal of neurology

authors： Bongioanni P,Lombardo F,Moscato G,Mosti S,Meucci G

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although there is growing and convincing evidence that socially deprived patients are at higher risk of stroke and worse outcomes, it remains controversial whether or not they suffer more severe stroke. This study aimed to evaluate the influence of social deprivation on initial clinical severity ...

journal_title：European journal of neurology

authors： Béjot Y,Guilloteau A,Joux J,Lannuzel A,Mimeau E,Mislin-Tritsch C,Fournel I,Bonithon-Kopp C,INDIA Study Group.

更新日期：2017-05-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a risk factor for cardiovascular disorders and different types of stroke. The present retrospective study investigates whether COPD is also a risk factor for the development of seizures in stroke patients. The study population consisted of 237 patients with stroke-relate...

journal_title：European journal of neurology

authors： De Reuck J,Proot P,Van Maele G

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate the prevalence of TOR1A, GNAL and THAP1 variants as the cause of dystonia in a cohort of Spanish patients with isolated dystonia and in the literature. METHODS:A population of 2028 subjects (including 1053 patients with different subtypes of isolated dystonia and 975 healthy controls)...

journal_title：European journal of neurology

authors： Gómez-Garre P,Jesús S,Periñán MT,Adarmes A,Alonso-Canovas A,Blanco-Ollero A,Buiza-Rueda D,Carrillo F,Catalán-Alonso MJ,Del Val J,Escamilla-Sevilla F,Espinosa-Rosso R,Fernández-Moreno MC,García-Moreno JM,García-Ruiz PJ,Giaco

更新日期：2020-11-11 00:00:00

abstract：:The incidence of the neuropathological lesions and the severity of the clinical symptoms in multiple sclerosis (MS) are correlated with the amount of the transferred autoreactive T cells. The balance between the T helper 1 (Th1) and T helper 2 (Th2) cytokine phenotypes may affect the activity of the disease in MS pati...

journal_title：European journal of neurology

authors： Ersoy E,Kuş CN,Sener U,Coker I,Zorlu Y

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dimethyl fumarate (DMF) causes a mean lymphocyte count drop of approximately 30% in relapsing-remitting multiple sclerosis (RRMS) patients. The relationship between this reduction and DMF effectiveness is controversial. The objective was to investigate if the decrease in absolute lymphocyte count...

journal_title：European journal of neurology

authors： Tsantes E,Curti E,Ferraro D,Lugaresi A,Baldi E,Montepietra S,Immovilli P,Simone AM,Mancinelli L,Strumia S,Vitetta F,Foschi M,Ferri C,Ferrarini C,Sola P,Granella F

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subthreshold depression (SubD) is characterized by clinically relevant depressive symptoms not meeting criteria for major depression. The possible association of SubD with subjective cognitive complaints and/or objective cognitive impairments was investigated in a sample of consecutive, non-demen...

journal_title：European journal of neurology

authors： Santangelo G,Vitale C,Trojano L,Angrisano MG,Picillo M,Errico D,Agosti V,Grossi D,Barone P

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Peritumoral brain edema in glioblastoma patients is a frequently encountered phenomenon that strongly contributes to neurological signs and symptoms. The role of peritumoral edema as a prognostic factor is controversial. MATERIALS AND METHODS:This multi-centre clinical retrospective study included 110 patie...

journal_title：European journal of neurology

authors： Schoenegger K,Oberndorfer S,Wuschitz B,Struhal W,Hainfellner J,Prayer D,Heinzl H,Lahrmann H,Marosi C,Grisold W

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the genetic contribution to stroke risk is well known, it remains unclear if young-onset stroke has a stronger genetic contribution than old-onset stroke. This study aims to compare the heritability of ischaemic stroke risk between young and old, using common genetic variants from whole-...

journal_title：European journal of neurology

authors： Bluher A,Devan WJ,Holliday EG,Nalls M,Parolo S,Bione S,Giese AK,Boncoraglio GB,Maguire JM,Müller-Nurasyid M,Gieger C,Meschia JF,Rosand J,Rolfs A,Kittner SJ,Mitchell BD,O'Connell JR,Cheng YC

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite numerous studies, the role of patent foramen ovale (PFO) as a risk factor for stroke due to paradoxical embolism is still controversial. On the assumption that specific lesion patterns, in particular multiple acute ischaemic lesions on diffusion-weighted magnetic resonance imaging, indica...

journal_title：European journal of neurology

authors： Feurer R,Sadikovic S,Esposito L,Schwarze J,Bockelbrink A,Hemmer B,Sander D,Poppert H

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is well established that patient-related constitutional features predispose to focal peripheral neuropathies. Some of these risk factors were investigated in common focal neuropathies encountered in patients referred for electromyography. METHODS:Gender, age, height and body mass index (BMI) ...

journal_title：European journal of neurology

authors： Martínez-Aparicio C,Jääskeläinen SK,Puksa L,Reche-Lorite F,Torné-Poyatos P,Paniagua Soto J,Falck B

更新日期：2020-03-01 00:00:00

abstract：:We report here 39 cases in which definite multiple sclerosis (MS) was precipitated or exacerbated by specific hyperextension-hyperflexion cervical cord trauma. The worsening or onset of the symptomatic disease bore a striking temporal relationship to the focal injury. Our data suggests that central nervous system (CNS...

journal_title：European journal of neurology

authors： Chaudhuri A,Behan PO

更新日期：2001-11-01 00:00:00

abstract：:Recent studies suggest an association between Chlamydia pneumoniae infection with atherosclerosis, including cerebrovascular disease. We investigated the prevalence of Chlamydial seropositivity in patients with acute ischaemic stroke syndrome compared with age- and sex-matched control subjects. Specific antibodies (Ig...

journal_title：European journal of neurology

authors： Madre JG,Garcia JL,Gonzalez RC,Montero JM,Paniagua EB,Escribano JR,Martinez JD,Cenjor RF

更新日期：2002-05-01 00:00:00

abstract：:Neurosarcoidosis occurs in 5-15% of sarcoidosis cases. Approximately 50% of patients with neurosarcoidosis present with a neurological disease at the time sarcoidosis is first diagnosed. Spinal sarcoidosis is rare. We report the case of a 61-year-old man with a highly aspecific intramedullary lesion as the first manif...

journal_title：European journal of neurology

authors： Caneparo D,Lucetti C,Nuti A,Cipriani G,Tessa C,Fazzi P,Bonuccelli U

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Consensus guidelines on the definition, investigation, and treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) have been previously published in European Journal of Neurology and Journal of the Peripheral Nervous System. OBJECTIVES:To revise these guidelines. METHODS:Disease exper...

journal_title：European journal of neurology

authors： Van den Bergh PY,Hadden RD,Bouche P,Cornblath DR,Hahn A,Illa I,Koski CL,Léger JM,Nobile-Orazio E,Pollard J,Sommer C,van Doorn PA,van Schaik IN,European Federation of Neurological Societies.,Peripheral Nerve Society.

更新日期：2010-03-01 00:00:00