A national stroke quality register: 12 years experience from a participating hospital.

abstract：BACKGROUND:Migraine with aura (MA) has been found to be a risk factor for cardiovascular disease including ischaemic stroke and myocardial infarction. Studies have also reported a higher prevalence of unfavourable cardiovascular risk factors amongst migraineurs, but results have been conflicting as to whether this is r...

journal_title：European journal of neurology

authors： Winsvold BS,Hagen K,Aamodt AH,Stovner LJ,Holmen J,Zwart JA

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The burden of multiple sclerosis (MS) includes fatigue, depression and worsening of health-related quality of life (HRQOL). These changes have not been yet measured in neuromyelitis optica (NMO). Our aim was to assess the HRQOL, fatigue and depression in NMO. METHODS:We administered French validated self-qu...

journal_title：European journal of neurology

authors： Chanson JB,Zéphir H,Collongues N,Outteryck O,Blanc F,Fleury M,Vermersch P,de Seze J

更新日期：2011-06-01 00:00:00

abstract：:To study the efficacy and safety of tolperisone - a centrally acting muscle relaxant with membrane stabilizing activity - in the treatment of stroke-related spasticity. This was a randomized, double-blind, placebo-controlled, multicenter study with parallel groups. Treatment lasted 12 weeks and was started with a titr...

journal_title：European journal of neurology

authors： Stamenova P,Koytchev R,Kuhn K,Hansen C,Horvath F,Ramm S,Pongratz D

更新日期：2005-06-01 00:00:00

abstract：:Digital subtraction angiography (DSA) is considered to be the 'gold standard' for confirmation of severe (70-99%) stenoses of internal carotid arteries (ICAs). However, it is associated with a risk of complications. The aim of this study was to assess the accuracy of ultrasonography (US), computed tomographic angiogra...

journal_title：European journal of neurology

authors： Herzig R,Burval S,Krupka B,Vlachová I,Urbánek K,Mares J

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Cognitive tests are known to be influenced by language, culture and education. In addition, there may be an impact of 'epoch' in cognition, because there is secular increase in scores of IQ tests in children. If we assume this is a long lasting process, then it should persist later in life. METHODS:To test ...

journal_title：European journal of neurology

authors： Morgado J,Rocha CS,Maruta C,Guerreiro M,Martins IP

更新日期：2010-05-01 00:00:00

abstract：:The natural history of thymoma remains unpredictable because of the possibility of recurrence not infrequent after resection, but generally confined to the mediastinum Rufini et al. (1997). ...

journal_title：European journal of neurology

authors： Moretti R,Nasuelli D,Torre P,Antonello RM,Cazzato G,Stanta G

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Migraine is a complex and disabling neurological disorder, the exact neurological mechanisms of which remain unclear. The thalamus is considered to be the hub of the central processing and integration of nociceptive information, as well as the modulation of these processes. METHODS:A total of 48...

journal_title：European journal of neurology

authors： Qin ZX,Su JJ,He XW,Zhu Q,Cui YY,Zhang JL,Wang MX,Gao TT,Tang W,Hu Y,Liu YS,Qiao Y,Liu JR,Li JQ,Du XX

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cognitive impairment is common in Parkinson's disease (PD), even in the early stages. We aimed to assess the relationship between insulin-like growth factor-1 (IGF-1) and cognitive functions in early, drug-naïve patients with PD. METHODS:Serum IGF-1 was measured in 65 early, drug-naïve patients ...

journal_title：European journal of neurology

authors： Pellecchia MT,Santangelo G,Picillo M,Pivonello R,Longo K,Pivonello C,Vitale C,Amboni M,De Rosa A,Moccia M,Erro R,De Michele G,Santoro L,Colao A,Barone P

更新日期：2014-05-01 00:00:00

abstract：:Phosphorylated α-synuclein (phosαSYN) containing inclusions in neurons (Lewy bodies, LB) and nerve terminals (Lewy neurites, LN), the pathological hallmark of Parkinson's disease (PD), are not confined to the central nervous system, but have also been reported in peripheral tissues. However, the usefulness of αSYN/pho...

journal_title：European journal of neurology

authors： Schneider SA,Boettner M,Alexoudi A,Zorenkov D,Deuschl G,Wedel T

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The expanded repeat length in ATXN1 negatively correlates with age at onset (AAO) of spinocerebellar ataxia type 1 (SCA1) but can explain only part of it, indicating that other factors affect AAO. Some studies have explored the influence of non-causative CAG repeats on the AAO of SCA patients. Ho...

journal_title：European journal of neurology

authors： Wang P,Chen Z,Peng Y,Cao L,Li X,Wang C,Yang H,Peng H,Shi Y,Zhou X,Li T,Feng L,Wu C,Qiu R,Xia K,Tang B,Jiang H

更新日期：2019-08-01 00:00:00

abstract：:The present review of epidemiologic studies on migraine and headache in Europe is part of a larger initiative by the European Brain Council to estimate the costs incurred because of brain disorders. Summarizing the data on 1-year prevalence, the proportion of adults in Europe reporting headache was 51%, migraine 14%, ...

journal_title：European journal of neurology

authors： Stovner LJ,Zwart JA,Hagen K,Terwindt GM,Pascual J

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The purpose of the study is to investigate the epidemiology and medical expenses of Wilson's disease in Taiwan. METHODS:Cases of Wilson's disease were identified from the National Health Insurance Research Database with corresponding International Classification of Diseases, Ninth Revision (ICD-9) code 275....

journal_title：European journal of neurology

authors： Lai CH,Tseng HF

更新日期：2010-06-01 00:00:00

abstract：:The genetic underpinnings of frontotemporal dementia (FTD), a rare yet early onset disorder still remains elusive. As FTD is characterized by a serotonergic deficit in the frontal lobe, and as some symptoms of FTD resemble conditions of monoamino oxidase A (MAO-A) deficiency, MAO-A is an attractive candidate gene for ...

journal_title：European journal of neurology

authors： Reif A,Scarpini E,Venturelli E,Töpner T,Fenoglio C,Lesch KP,Galimberti D

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with the cerebellar variant of multiple system atrophy (MSA-C) often show cognitive deficits in various cognitive domains. The association between morphometric changes in cortical and subcortical structures and cognitive impairments in MSA-C were investigated to explore the neural correl...

journal_title：European journal of neurology

authors： Lee MJ,Shin JH,Seoung JK,Lee JH,Yoon U,Oh JH,Jung DS,Kim EJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with chronic focal epilepsy may have atrophy of brain structures important for the generation and maintenance of seizures. However, little research has been conducted in patients with newly diagnosed focal epilepsy (NDfE), despite it being a crucial point in time for understanding the un...

journal_title：European journal of neurology

authors： Leek NJ,Neason M,Kreilkamp BAK,de Bezenac C,Ziso B,Elkommos S,Das K,Marson AG,Keller SS

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Falling is considered an important public health problem among older people. A recent cross-sectional study suggested that cognitive frailty (CF) is associated with falls. We aimed to explore whether CF is a risk factor for falls in a population-based longitudinal study. METHODS:Using data from ...

journal_title：European journal of neurology

authors： Ma Y,Li X,Pan Y,Zhao R,Wang X,Jiang X,Li S

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intrathecal immunoglobulin (Ig) synthesis occurs in various chronic inflammatory neurological diseases. Different formulae have been developed for quantitative determination of Ig synthesis within the cerebrospinal fluid (CSF) compartment. The hyperbolic formula of Reiber is frequently used which...

journal_title：European journal of neurology

authors： Auer M,Hegen H,Zeileis A,Deisenhammer F

更新日期：2016-04-01 00:00:00

abstract：:We present the baseline characteristics of 101 patients with normal pressure hydrocephalus (NPH), entering a study that evaluates the diagnostic reliability of CSF outflow resistance. Patients were assessed by a gait scale consisting of 10 features of walking and the number of steps and seconds necessary for 10 m, a d...

journal_title：European journal of neurology

authors： Boon AJ,Tans JT,Delwel EJ,Egeler-Peerdeman SM,Hanlo PW,Wurzer JA,Hermans J

更新日期：1997-01-01 00:00:00

abstract：:Multiple sclerosis (MS) is a T-cell-mediated autoimmune demyelinating disease of the central nervous system, associated with an altered cytokine network. We previously assayed peripheral blood T-lymphocyte binding for two prototypic cytokines, tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), and foun...

journal_title：European journal of neurology

authors： Bongioanni P,Lombardo F,Moscato G,Mosti S,Meucci G

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In a longitudinal population-based dataset of patients with multiple sclerosis (MS), we have previously observed a substantial increase in the female to male sex ratio in Canada over the last 50 years. Here, we aimed to determine whether this change in sex ratio is related to the clinical course ...

journal_title：European journal of neurology

authors： Ramagopalan SV,Byrnes JK,Orton SM,Dyment DA,Guimond C,Yee IM,Ebers GC,Sadovnick AD

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Venous drainage of dural arteriovenous fistula (DAVF) with dementia has never been reported. The aim of this study was to discover if specific vascular conditions exist to develop dementia in patients with DAVF. METHODS:Venous drainage in patients embolized in our centre between 1996 and 2012 fo...

journal_title：European journal of neurology

authors： Labeyrie MA,Lenck S,Saint-Maurice JP,Bresson D,Houdart E

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anticipatory postural adjustments (APAs), prior to step initiation, are bradykinetic in advanced Parkinson's disease (PD) and may be one of the factors associated with 'start hesitation'. However, little is known about APAs in the early stage of PD. In this study, we determined whether body-worn ...

journal_title：European journal of neurology

authors： Mancini M,Zampieri C,Carlson-Kuhta P,Chiari L,Horak FB

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:The presence of the apolipoprotein E (ApoE) 4 genotype is associated with an earlier age of onset for Alzheimer's disease (AD) and several other neurodegenerative disorders. The objective of this study was to investigate the effect of ApoE genotypes on the clinical course of amyotrophic lateral sclerosis (AL...

journal_title：European journal of neurology

authors： Jawaid A,Poon M,Strutt AM,Rice LK,McDowell EJ,Salamone AR,Qureshi SU,Simpson E,Appel SH,York MK,Schulz PE

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited cerebral small vessel disease that may lead to disability and whose phenotype modulators are still unknown. METHODS:In the MIcrovascular LEukoencephalopathy Study (MILES), we asse...

journal_title：European journal of neurology

authors： Ciolli L,Pescini F,Salvadori E,Del Bene A,Pracucci G,Poggesi A,Nannucci S,Valenti R,Basile AM,Squarzanti F,Bianchi S,Dotti MT,Adriano E,Balestrino M,Federico A,Gandolfo C,Inzitari D,Pantoni L

更新日期：2014-01-01 00:00:00

abstract：:Studies of the cephalic vascular system have markedly contributed towards an understanding of the mechanisms of migraine pain. Whereas cerebral blood flow changes, and thereby changes in the arterioles, correlate poorly with migraine headache, abnormal regulation of the large cranial arteries seems to play a significa...

journal_title：European journal of neurology

authors： Thomsen LL

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:CACNA1S encodes Cav 1.1, a voltage sensor for muscle excitation-contraction coupling, which activates the ryanodine receptor 1 (RYR1) leading to calcium release from the sarcoplasmic reticulum. CACNA1S mutations cause hypokalemic periodic paralysis, malignant hyperthermia and congenital myopathy....

journal_title：European journal of neurology

authors： Anandan C,Cipriani MA,Laughlin RS,Niu Z,Milone M

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence for effective treatment options for orthostatic hypotension (OH) in Parkinson's disease (PD) is scarce. Elevation of cholinergic tone with pyridostigmine bromide has been reported as a way to improve blood pressure (bp) regulation in neurogenic hypotension without causing supine hyperten...

journal_title：European journal of neurology

authors： Schreglmann SR,Büchele F,Sommerauer M,Epprecht L,Kägi G,Hägele-Link S,Götze O,Zimmerli L,Waldvogel D,Baumann CR

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The involvement of metabolic factors in the development of dementia has received much attention. However, previous studies have yielded conflicting results regarding how blood adipocytokine level impacts cognitive decline and dementia. This study aimed to clarify whether serum high-molecular-weig...

journal_title：European journal of neurology

authors： Kitagawa K,Miwa K,Okazaki S,Sakaguchi M,Mochizuki H

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fabry disease is an X-linked disease, and enzyme-based screening methods are not suitable for female patients. METHODS:In total, 1000 young stroke patients (18-55 years, 661 with ischaemic stroke and 339 with hypertensive intracerebral hemorrhage) were recruited. The Sequenom iPLEX assay was use...

journal_title：European journal of neurology

authors： Lee TH,Yang JT,Lee JD,Chang KC,Peng TI,Chang TY,Huang KL,Liu CH,Ryu SJ,Burlina AP

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Superficial siderosis of the central nervous system is a sporadic finding in magnetic resonance imaging, resulting from recurrent bleedings into the subarachnoid space. This study aimed to determine the frequency of spinal dural cerebrospinal fluid (CSF) leaks amongst patients with a symmetric in...

journal_title：European journal of neurology

authors： Friedauer L,Rezny-Kasprzak B,Steinmetz H,du Mesnil de Rochemont R,Foerch C

更新日期：2020-10-24 00:00:00