当前位置： SCI文献检索 > AMERICAN JOURNAL OF NEPHROLOGY期刊下所有文献 > Low levels of serum ferritin lead to adequate hemoglobin levels and good survival in hemodialysis patients.

Low levels of serum ferritin lead to adequate hemoglobin levels and good survival in hemodialysis patients.

Abstract：

BACKGROUND:The optimal level of serum ferritin (s-ft) for anemia control and good survival in hemodialysis (HD) patients remains unclear. A 10-year survey was performed to clarify the appropriate quantities of s-ft and investigate the relationships among s-ft, transferrin saturation (TSAT), and mortality in HD patients. METHODS:HD outpatients (n = 125) treated with erythropoiesis-stimulating agents (ESA) were followed for 10 years. The ESA and low-dose iron supplement dosages were adjusted to maintain the hemoglobin (Hb) at 10-11 g/dl, according to Japanese guidelines. The Kaplan-Meier method, log-rank tests, and the Cox proportional hazards model were used for performing the statistical analyses. The interactions among the Hb, s-ft, and TSAT were analyzed using a multiple linear regression model. Patients with TSAT ≥20% were classified according to the s-ft cutoff values: group 1 (s-ft <30 ng/ml); group 2 (s-ft 30-80 ng/ml); group 3 (s-ft >80 ng/ml); TSAT <20% was a predictor of poor outcome. RESULTS:The survival rate in group 2 was significantly higher than that in other groups (p = 0.013), and the Cox proportional hazards model analysis showed a good effect of low levels of s-ft on patients' survival. The multiple linear regression model showed a strong effect of s-ft on the Hb (log [s-ft], β-coefficient -0.45: 95% confidence interval -0.65 to -0.26, p < 0.001). CONCLUSION:This study revealed that low levels of s-ft have a beneficial effect on the outcome of HD patients receiving ESA. Thus, the optimal s-ft level might be lower than that established previously for these patients.

journal_name

Am J Nephrol

journal_title

American journal of nephrology

authors

Ogawa C,Tsuchiya K,Kanda F,Maeda T

doi

10.1159/000370317

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

561-70

issue

6

eissn

0250-8095

issn

1421-9670

pii

000370317

journal_volume

40

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF NEPHROLOGY文献大全
  • Intradialytic exercise in hemodialysis patients: a systematic review and meta-analysis.

    abstract：BACKGROUND AND OBJECTIVE:Hemodialysis (HD) patients are more inactive, leading to poor functional capacity and quality of life; this may be reversed with intradialytic exercise training. To systematically evaluate the efficacy and safety of intradialytic exercise for HD patients, we conducted a meta-analysis of the pub...

    journal_title：American journal of nephrology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1159/000368722

    authors： Sheng K,Zhang P,Chen L,Cheng J,Wu C,Chen J

    更新日期：2014-01-01 00:00:00

  • Albuminuria Testing by Race and Ethnicity among Patients with Hypertension with and without Diabetes.

    abstract：BACKGROUND:Detection of chronic kidney disease (CKD) with urine albumin-to-creatinine ratio (UACR) among patients with hypertension (HTN) provides an opportunity for early treatment, potentially mitigating risk of CKD progression and cardiovascular complications. Differences in UACR testing patterns among racial/ethnic...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000500706

    authors： Lee J,Chu C,Guzman D,Fontil V,Velasquez A,Powe NR,Tuot DS

    更新日期：2019-01-01 00:00:00

  • Elevated osteoprotegerin predicts declining renal function in elderly women: a 10-year prospective cohort study.

    abstract：BACKGROUND:Elevated osteoprotegerin (OPG) levels are inversely correlated with creatinine clearance and end-stage renal disease in patients with diabetes, however its role in predicting decline in renal function and progression to a more advanced stage disease in the elderly general population is unknown. METHODS:This...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000357787

    authors： Lewis JR,Lim WH,Zhu K,Wong G,Dhaliwal SS,Lim EM,Ueland T,Bollerslev J,Prince RL

    更新日期：2014-01-01 00:00:00

  • Primary renal hematuria presenting as unilateral gross hematuria.

    abstract：:A patient with unilateral gross hematuria was found to have mesangial proliferation and IgM deposition on renal biopsy, consistent with the entity of primary renal hematuria. This case refutes previous assumptions that renal biopsy is normal in patients with unilateral hematuria. Glomerular lesions may be more common ...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000167127

    authors： Tapp DC,Whitaker WR,Copley JB

    更新日期：1986-01-01 00:00:00

  • Research Themes and Trends in Ten Top-Ranked Nephrology Journals: A Text Mining Analysis.

    abstract：BACKGROUND:Nephrology research is expanding, and harnessing the much-needed information and data for the practice of evidence-based medicine is becoming more challenging. In this study, we used the natural language processing and text mining approach to mitigate some of these challenges. METHODS:We analyzed 17,412 abs...

    journal_title：American journal of nephrology

    pub_type： 杂志文章,评审

    doi：10.1159/000504871

    authors： Zengul FD,Lee T,Delen D,Almehmi A,Ivankova NV,Mehta T,Topuz K

    更新日期：2020-01-01 00:00:00

  • Universal Sustained Viral Response to the Combination of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir with/without Ribavirin in Patients on Hemodialysis Infected with Hepatitis C Virus Genotypes 1 and 4.

    abstract：BACKGROUND:Hepatitis C virus (HCV) infection is highly prevalent among patients on hemodialysis (HD) and is associated with poor prognosis. Treatment with interferon and ribavirin is poorly tolerated, and few data are available on the impact of new direct-acting antivirals (DAAs). This study was intended to analyze the...

    journal_title：American journal of nephrology

    pub_type： 杂志文章,多中心研究

    doi：10.1159/000454819

    authors： Abad S,Vega A,Hernández E,Mérida E,de Sequera P,Albalate M,Macías N,Milla M,López-Gómez JM

    更新日期：2017-01-01 00:00:00

  • Origins and early reception of clinical dialysis.

    abstract：:Several medical inventors in Europe and North America brought the artificial kidney (hemodialysis) to practical usefulness in the late 1940s, but there were very few early successes. It was used at first for only desperate cases of acute renal failure. Renal authorities in the 'metabolic' tradition favored newly quant...

    journal_title：American journal of nephrology

    pub_type： 历史文章,杂志文章

    doi：10.1159/000169117

    authors： Peitzman SJ

    更新日期：1997-01-01 00:00:00

  • Histopathologic Features that Predict Transplant Glomerulopathy Progression in a Chinese Cohort.

    abstract：BACKGROUND:Transplant glomerulopathy (TG) represents a major cause of long-term allograft failure and is the leading cause of overall post-transplant proteinuria. The extent to which histopathologic features predicts prognostication is uncertain. METHODS:A single-center retrospective cohort with biopsy-proven TG was i...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000500043

    authors： Li X,Chen J,Cheng D,Wang W,Xie K,Zhang M,Xu F,Wen J,Tang Z

    更新日期：2019-01-01 00:00:00

  • Healthy behaviors, risk factor control and awareness of chronic kidney disease.

    abstract：BACKGROUND/AIMS:The association between chronic kidney disease (CKD) awareness and healthy behaviors is unknown. We examined whether CKD self-recognition is associated with healthy behaviors and achieving risk-reduction targets known to decrease risk of cardiovascular morbidity and CKD progression. METHODS:CKD awarene...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000346712

    authors： Tuot DS,Plantinga LC,Judd SE,Muntner P,Hsu CY,Warnock DG,Gutiérrez OM,Safford M,Powe NR,McClellan WM,REGARDS Investigators.

    更新日期：2013-01-01 00:00:00

  • Proteinuria and progression in human glomerular diseases.

    abstract：:Proteinuria is characteristic of many glomerular conditions, and often exceeds 2-3 g/24 h. There are several possible routes by which such profuse proteinuria might contribute to progression of the underlying pathology, whatever its type. First, proteinuria leads to a transit of protein through glomerular structures, ...

    journal_title：American journal of nephrology

    pub_type： 杂志文章,评审

    doi：10.1159/000168199

    authors： Cameron JS

    更新日期：1990-01-01 00:00:00

  • Clinical implications of antineutrophil cytoplasmic antibody test in lupus nephritis.

    abstract：:To elucidate the prevalence and clinical implications of antineutrophil cytoplasmic antibody (ANCA) in lupus nephritis (LN), we examined ANCA by indirect immunofluorescence and by ELISA against antilactoferrin (anti-LF) and antimyeloperoxidase (anti-MPO) antibody. To discriminate perinuclear ANCA (pANCA) with antinucl...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000013557

    authors： Chin HJ,Ahn C,Lim CS,Chung HK,Lee JG,Song YW,Lee HS,Han JS,Kim S,Lee JS

    更新日期：2000-01-01 00:00:00

  • Sevoflurane protects against acute kidney injury in a small-size liver transplantation model.

    abstract：BACKGROUND:Living donor liver transplantation (LDLT) patients run the risk of developing acute kidney injury (AKI) and subsequent chronic kidney disease, affecting morbidity and mortality. Sevoflurane has anti-inflammation properties, and renal ischemia/reperfusion under sevoflurane anesthesia resulted in drastic impro...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000319623

    authors： Kong HY,Zhu SM,Wang LQ,He Y,Xie HY,Zheng SS

    更新日期：2010-01-01 00:00:00

  • Increased Incident Ischemic Stroke Risk in Advanced Kidney Disease: A Large-Scale Real-World Data Study.

    abstract：INTRODUCTION:Evidence using real-world data is sparse regarding the effects of oral anticoagulants (OACs) among patients with kidney disease. The aim of this study was to investigate the effects of kidney disease on ischemic stroke (IS) or systemic embolism (SE) among patients taking OAC, using large-scale real-world d...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000509567

    authors： Maeda T,Nishi T,Funakoshi S,Tada K,Tsuji M,Satoh A,Kawazoe M,Yoshimura C,Arima H

    更新日期：2020-01-01 00:00:00

  • Cardiovascular Outcomes in Action to Control Cardiovascular Risk in Diabetes: Impact of Blood Pressure Level and Presence of Kidney Disease.

    abstract：BACKGROUND:Persons with chronic kidney disease (CKD) represent a population prone to cardiovascular disease (CVD) but vulnerable to adverse medication effects. We assessed the impact of intensive antihypertensive therapy on the cerebrovascular and other CVD outcomes in high-risk patients with type 2 diabetes and baseli...

    journal_title：American journal of nephrology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1159/000446122

    authors： Papademetriou V,Zaheer M,Doumas M,Lovato L,Applegate WB,Tsioufis C,Mottle A,Punthakee Z,Cushman WC,ACCORD Study Group.

    更新日期：2016-01-01 00:00:00

  • Association of Acute Kidney Injury with Cardiovascular Events and Death in Systolic Blood Pressure Intervention Trial.

    abstract：RATIONALE AND OBJECTIVE:In the Systolic Blood Pressure Intervention Trial, the possible relationships between acute kidney injury (AKI) and risk of major cardiovascular events and death are not known. STUDY DESIGN:Post hoc analysis of a multicenter, randomized, controlled, open-label clinical trial. SETTING AND PARTI...

    journal_title：American journal of nephrology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1159/000499574

    authors： Dieter BP,Daratha KB,McPherson SM,Short R,Alicic RZ,Tuttle KR

    更新日期：2019-01-01 00:00:00

  • CYP3A4 and CYP3A5 polymorphisms and blood pressure response to amlodipine among African-American men and women with early hypertensive renal disease.

    abstract：PURPOSE:To explore the association between CYP3A4 and CYP3A5 gene polymorphisms and blood pressure response to amlodipine among participants from the African-American Study of Kidney Disease and Hypertension Trial randomized to amlodipine (n = 164). METHODS:Cox proportional hazards models were used to determine the ri...

    journal_title：American journal of nephrology

    pub_type： 杂志文章,随机对照试验

    doi：10.1159/000258688

    authors： Bhatnagar V,Garcia EP,O'Connor DT,Brophy VH,Alcaraz J,Richard E,Bakris GL,Middleton JP,Norris KC,Wright J,Hiremath L,Contreras G,Appel LJ,Lipkowitz MS,AASK Study Investigators.

    更新日期：2010-01-01 00:00:00

  • Effect of first and subsequent use of hemodialyzers on patient well-being. Analysis of the incidence of symptoms and events and description of a syndrome associated with new dialyzer use.

    abstract：:To determine the effect of multiple dialyzer use on intradialytic symptoms, data from 26,592 successive dialyses on 147 patients were analyzed. Over the 26-month period of study 4,933 new dialyzers were used. All symptoms, considered together, occurred 1.3 times more frequently during the initial than during the subse...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000167063

    authors： Robson MD,Charoenpanich R,Kant KS,Peterson DW,Flynn J,Cathey M,Pollak VE

    更新日期：1986-01-01 00:00:00

  • Distal nephron function in Bartter's syndrome: abnormal conductance to chloride in the cortical collecting tubule?

    abstract：:Five patients with the clinical patterns of Bartter's syndrome underwent a series of clearance studies in order to characterize the underlying tubule defect. Free water generation during maximal water diuresis (CH2O), expressed as percentage of the distal delivery (CH2O + CCl), was lower in the patients (72.5 +/- 3.2%...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000168451

    authors： Colussi G,Rombolà G,Verde G,Airaghi C,Loli P,Minetti L

    更新日期：1992-01-01 00:00:00

  • Rapidly progressive interstitial renal fibrosis associated with Chinese herbal medications.

    abstract：BACKGROUND/AIM:Nephropathy after ingestion of Chinese herbs is known as a rapidly progressive form of interstitial renal fibrosis after a slimming regimen containing aristolochic acid that was identified first in Belgium. Intake of traditional Chinese herbal medicines is very popular in Taiwan. So we looked for similar...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000046647

    authors： Chang CH,Wang YM,Yang AH,Chiang SS

    更新日期：2001-11-01 00:00:00

  • CAPD-associated peritonitis caused by Alcaligenes xylosoxidans sp. xylosoxidans.

    abstract：:Alcaligenes xylosoxidans is an uncommon cause of peritonitis in patients on maintenance continuous ambulatory peritoneal dialysis (CAPD). Peritonitis caused by A. xylosoxidans usually carries a poor prognosis because of the pathogen's virulence and its universal resistance to most antimicrobial agents. Even after earl...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000046657

    authors： Tang S,Cheng CC,Tse KC,Li FK,Choy BY,Chan TM,Lai KN

    更新日期：2001-11-01 00:00:00

  • Treatment of hepatitis B virus associated glomerulonephritis with recombinant human alpha interferon.

    abstract：:To evaluate the therapeutic effect of recombinant human alpha-interferon (alpha-IFN) on hepatitis B virus associated glomerulonephritis (HBV-GN) and the relationship between the seroconversion of viral antigens and the change of proteinuria, the hepatitis B viral markers and urinary protein were monitored during alpha...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000169083

    authors： Chung DR,Yang WS,Kim SB,Yu E,Chung YH,Lee Y,Park JS

    更新日期：1997-01-01 00:00:00

  • D-penicillamine-induced crescentic glomerulonephritis and antimyeloperoxidase antibodies in a patient with scleroderma. Case report and review of the literature.

    abstract：:Therapeutic use of D-penicillamine has been associated with a range of adverse effects. We present a patient with scleroderma, treated with D-penicillamine for 5 years, who developed severe renal failure due to rapidly progressive glomerulonephritis with both crescents and subepithelial immune deposits on renal biopsy...

    journal_title：American journal of nephrology

    pub_type： 杂志文章,评审

    doi：10.1159/000169183

    authors： Karpinski J,Jothy S,Radoux V,Levy M,Baran D

    更新日期：1997-01-01 00:00:00

  • Influence of Judaism and Jewish physicians on Greek and Byzantine medicine and their contribution to nephrology.

    abstract：:Both the Old Testament and the Talmud contain a great deal of information on medicine, nephrology, health and disease. The basic premise of early Jewish medicine is based on the notion that disease is due to structural changes in internal organs. This is in contrast to the mythical dogma of humoralism as the basis of ...

    journal_title：American journal of nephrology

    pub_type： 传,历史文章,杂志文章

    doi：10.1159/000169107

    authors： Massry SG,Smogorzewski M,Hazani E,Shasha SM

    更新日期：1997-01-01 00:00:00

  • Elevated preoperative phosphorus levels are an independent risk factor for cardiovascular mortality.

    abstract：BACKGROUND/AIMS:Serum phosphorus levels have been associated with adverse long-term outcome in several populations, however, no prior studies evaluated short-term postoperative outcome. The present study evaluated the predictive value of phosphorus levels on 30-day outcome after vascular surgery. METHODS:The study inc...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000315856

    authors： van Kuijk JP,Flu WJ,Chonchol M,Valentijn TM,Verhagen HJ,Bax JJ,Poldermans D

    更新日期：2010-01-01 00:00:00

  • Albuminuria Regression and All-Cause Mortality among Insulin-Treated Patients with Type 2 Diabetes: Analysis of a Large UK Primary Care Cohort.

    abstract：BACKGROUND:Overt albuminuria (urinary albumin-creatinine ratio [ACR] > 300 mg/g) is an established risk factor for progression of nephropathy and total mortality. However, whether a reduction in ACR translates into a reduction in mortality and/or cardiovascular (CV) events among insulin-treated patients with type 2 dia...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000496276

    authors： Anyanwagu U,Donnelly R,Idris I

    更新日期：2019-01-01 00:00:00

  • Tetracycline-inducible gene expression in conditionally immortalized mouse podocytes.

    abstract：BACKGROUND:Conditionally immortalized podocytes are valuable research tools but are difficult to efficiently transfect and do not provide graded transgene expression. METHODS:Conditionally immortalized mouse podocyte cell lines were established employing a tetracycline-inducible system. Glomerular cells, isolated from...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000151770

    authors： Kajiyama H,Titus S,Austin CP,Chiotos K,Matsumoto T,Sakairi T,Kopp JB

    更新日期：2009-01-01 00:00:00

  • Recovery of minimal change nephrotic syndrome and acute renal failure in a patient withRenal cell carcinoma.

    abstract：:We describe a 78-year-old patient with nephrotic syndrome due to minimal-change glomerulopathy, associated with a renal adenocarcinoma. Oliguric acute renal failure requiring hemodialysis was also observed. Surgical removal of the tumor and corticosteroid therapy resulted in resolution of the nephrotic state and impro...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000013365

    authors： Auguet T,Lorenzo A,Colomer E,Zamora A,García C,Martínez-Vea A,Richart C,Oliver JA

    更新日期：1998-01-01 00:00:00

  • Polymorphic genes for kinin receptors, nephropathy and blood pressure in type 2 diabetic patients.

    abstract：BACKGROUND/AIMS:There is evidence that hereditary predisposition contributes to the development of diabetic nephropathy and hypertension. Polymorphisms in the genes for bradykinin receptors (B(1)R and B(2)R) were found to be associated with decreased risk of the development of end-stage renal disease. This study examin...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000068035

    authors： Zychma MJ,Gumprecht J,Trautsolt W,Szydlowska I,Grzeszczak W

    更新日期：2003-03-01 00:00:00

  • Peritoneal sclerosis in peritoneal dialysis patients.

    abstract：:Peritoneal sclerosis, a disorder similar to that previously identified in nonuremic patients, is being noted in peritoneal dialysis patients with increasing frequency. The etiology in dialysis patients remains unknown. An association with previous or ongoing peritoneal inflammation or irritation suggests that the inci...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000166799

    authors： Ing TS,Daugirdas JT,Gandhi VC

    更新日期：1984-01-01 00:00:00

  • Impact of Serum Bicarbonate Levels on Muscle Mass and Kidney Function in Pre-Dialysis Chronic Kidney Disease Patients.

    abstract：BACKGROUND:Treatment of metabolic acidosis to target the higher serum bicarbonate level than guideline recommendation may downregulate muscle protein degradation and improve renal function among chronic kidney disease (CKD) patients. We conducted a study to test the effects of increased serum bicarbonate level on muscl...

    journal_title：American journal of nephrology

    pub_type： 杂志文章

    doi：10.1159/000504557

    authors： Kittiskulnam P,Srijaruneruang S,Chulakadabba A,Thokanit NS,Praditpornsilpa K,Tungsanga K,Eiam-Ong S

    更新日期：2020-01-01 00:00:00