Quality of life among long-term survivors of intensive care.

abstract：:The metabolic support of critically ill patients is a relatively new topic of active research and discussion, and surprisingly little is known about the effects of critical illness on metabolic physiology and activity. The metabolic changes seen in critical illness are highly complex, and how and when to treat them ar...

journal_title：Critical care medicine

authors： Vincent JL

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To elucidate sources of variability in the estimate of treatment effects in a successful phase 3 trial in severe sepsis and to assess their implications on the design of future clinical trials. DESIGN:Retrospective evaluation of prospectively defined subgroups from a large phase 3, placebo-controlled clinica...

journal_title：Critical care medicine

authors： Macias WL,Vallet B,Bernard GR,Vincent JL,Laterre PF,Nelson DR,Derchak PA,Dhainaut JF

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To describe opioid use after ICU admission, identify factors associated with chronic opioid use after critical care, and determine if chronic opioid use is associated with an increased risk of death. DESIGN:Retrospective cohort study. SETTING:Sweden including all registered ICU admissions between 2010 and 2...

journal_title：Critical care medicine

authors： von Oelreich E,Eriksson M,Sjölund KF,Discacciati A,Larsson E,Oldner A

更新日期：2021-01-28 00:00:00

abstract：:Assessment of creatinine clearance (CC) in ICU patients was compared using three methods. The reference method (CC 24 h) used measurements of serum creatinine and urinary creatinine after collection of urine over a 24-h period. The other two methods were predictive methods: the Kampmann nomogram and the formula develo...

journal_title：Critical care medicine

authors： Martin C,Alaya M,Bras J,Saux P,Gouin F

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVE:Fibrotic changes are initiated early in acute respiratory distress syndrome. This may involve overproliferation of alveolar type II cells. In an animal model of acute respiratory distress syndrome, we have shown that the administration of an adenoviral vector overexpressing the 70-kd heat shock protein (AdHSP...

journal_title：Critical care medicine

authors： Bromberg Z,Raj N,Goloubinoff P,Deutschman CS,Weiss YG

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between behavioral alterations and changes in monoaminergic systems provoked by ischemia-reperfusion liver injury in rats. DESIGN:Prospective, randomized, controlled animal study. SETTING:University animal laboratory. SUBJECTS:Male Wistar rats. INTERVENTIONS:Acute liver fai...

journal_title：Critical care medicine

authors： Adachi N,Inoue H,Arai T

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:Acute respiratory distress syndrome is occasionally seen in newborn infants due to a severe inflammatory process in the lungs that affects capillary-alveolar permeability, epithelial integrity, and type I and II pneumocyte function. The aim of this study was to investigate the effect of a topically applied nu...

journal_title：Critical care medicine

authors： Ankermann T,Reisner A,Wiemann T,Krams M,Köhler H,Krause MF

更新日期：2005-06-01 00:00:00

abstract：:Capnography is a valuable tool in the management of cardiac arrest, since end-tidal CO2 (PetCO2) correlates well with cardiac output and there are no other suitable noninvasive ways to measure this important variable during resuscitation. Animal studies also suggest that PetCO2 correlates well with the likelihood of r...

journal_title：Critical care medicine

authors： Callaham M,Barton C

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:To describe the long-term health-related quality of life (HRQL) of survivors of sepsis and to evaluate the reliability and validity of the medical outcomes study Short Form-36 (SF-36) in this population. STUDY DESIGN:Cross-sectional survey. SETTING:University intensive care unit. PATIENTS:Surviving patient...

journal_title：Critical care medicine

authors： Heyland DK,Hopman W,Coo H,Tranmer J,McColl MA

更新日期：2000-11-01 00:00:00

abstract：:offstudied hemodynamic and renal effects of increasing the dosage of dopamine (DP) by 5 micrograms/kg X min, in 7 patients with peritonitis and clinical findings of septic shock, all of whom were already receiving variable dosages of DP. Stroke index (SI) (p less than .01), except in 3 cases, and mean arterial pressur...

journal_title：Critical care medicine

authors： de la Cal MA,Miravalles E,Pascual T,Esteban A,Ruiz-Santana S

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:Intracranial pressure (ICP) monitoring is frequently used in intensive care treatment of patients with intracranial hemorrhage. Data demonstrating an improved outcome from this intervention are lacking. We analyzed standardized mortality ratios in patients with and without ICP monitoring to determine its effi...

journal_title：Critical care medicine

authors： Valentin A,Lang T,Karnik R,Ammerer HP,Ploder J,Slany J

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:Restoration of myocardial blood flow after ischemia triggers an inflammatory response involving toll-like receptors. Toll-like receptor 2 deficiency is associated with a reduced infarct size after myocardial ischemia and reperfusion. Because a marked mortality was observed in C3HeN wild-type mice, which was a...

journal_title：Critical care medicine

authors： Mersmann J,Koch A,Tran N,Zimmermann R,Granja TF,Larmann J,Herzog C,Theilmeier G,Bornstein SR,Kirschning CJ,Zacharowski K

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To determine whether clinically relevant airspace concentrations of beta2-adrenergic agonists stimulated maximal alveolar fluid clearance rates and to determine whether beta2 agonist therapy decreased pulmonary edema in experimental acute lung injury. DESIGN:Prospective randomized laboratory investigation. ...

journal_title：Critical care medicine

authors： McAuley DF,Frank JA,Fang X,Matthay MA

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVES:Brain death induces a massive inflammatory response. However, the influence of this inflammatory response on organ procurement, transplantation, and recipient outcome is unknown. We describe the inflammatory response characteristics in brain-dead organ donors and examine associations with organ transplantati...

journal_title：Critical care medicine

authors： Murugan R,Venkataraman R,Wahed AS,Elder M,Hergenroeder G,Carter M,Madden NJ,Powner D,Kellum JA,HIDonOR Study Investigators.

更新日期：2008-06-01 00:00:00

abstract：:Changes in pulmonary function and the development of atelectasis in the postoperative period have been well documented in the adult population. The use of incentive spirometry has been shown to be effective in the prevention of these postoperative complications. At the Hospital of Sick Children, we studied 17 children...

journal_title：Critical care medicine

authors： Krastins I,Corey ML,McLeod A,Edmonds J,Levison H,Moes F

更新日期：1982-08-01 00:00:00

abstract：OBJECTIVE:To study the pharmacokinetics of dopamine in hemodynamically stable adult patients. DESIGN:Prospective clinical study. SETTING:University hospital intensive care unit. PATIENTS:Fourteen patients (aged 43 to 73 yrs) recovering from esophageal surgery. INTERVENTION:Dopamine was infused and blood samples wer...

journal_title：Critical care medicine

authors： Le Corre P,Malledant Y,Tanguy M,Le Verge R

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:To determine the frequency and effects of weaning-related myocardial ischemia on weaning outcomes in patients with coronary artery disease. DESIGN:Prospective cohort study. SETTING:Medical and cardiac intensive care units of a 300-bed teaching community hospital. MEASUREMENTS AND MAIN RESULTS:Three-lead ST...

journal_title：Critical care medicine

authors： Srivastava S,Chatila W,Amoateng-Adjepong Y,Kanagasegar S,Jacob B,Zarich S,Manthous CA

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the pathophysiology involved in hypocalcemia in septic shock and to investigate the value of calcium administration. DESIGN:Prospective, randomized placebo-controlled trial with parallel groups. SETTING:Animal research laboratory at the University Hospital of Uppsala. SUBJECTS:Twenty-four pigs ...

journal_title：Critical care medicine

authors： Carlstedt F,Eriksson M,Kiiski R,Larsson A,Lind L

更新日期：2000-08-01 00:00:00

abstract：:The effect of positive-pressure ventilation (PPV) with PEEP on the release of alpha-atrial natriuretic peptide (ANP) was investigated in both humans and an experimental model. In the human study, systemic artery blood samples from 22 critically ill patients were analyzed for ANP. Seventeen of these patients received P...

journal_title：Critical care medicine

authors： Teba L,Dedhia HV,Schiebel FG,Blehschmidt NG,Lindner WJ

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:To determine the long-term outcome of noninvasive ventilation in chronic obstructive pulmonary disease patients who refused intubation for acute hypercapnic respiratory failure. DESIGN:Prospective, observational study. SETTING:Noninvasive ventilation unit in an acute regional hospital in Hong Kong. METHODS...

journal_title：Critical care medicine

authors： Chu CM,Chan VL,Wong IW,Leung WS,Lin AW,Cheung KF

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Heptafluoropropane is an inert gas commercially used as propellant for inhalers. Since heptafluoropropane can be detected in low concentrations, it could also be used as a tracer gas to measure functional residual capacity and ventilation homogeneity. The aim of the present study was to validate functional re...

journal_title：Critical care medicine

authors： Proquitté H,Kusztrich A,Auwärter V,Pragst F,Wauer RR,Schmalisch G

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To determine the utility of thoracic computed tomography (TCT) in the initial assessment of critically ill patients with chest injuries. DESIGN:Prospective observational study of cohorts. SETTING:Trauma intensive care unit (ICU) of a Spanish Level III hospital (US equivalent Level I). PATIENTS:Three hundre...

journal_title：Critical care medicine

authors： Guerrero-López F,Vázquez-Mata G,Alcázar-Romero PP,Fernández-Mondéjar E,Aguayo-Hoyos E,Linde-Valverde CM

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Procalcitonin (PCT), a marker of bacterial sepsis, may also act as a mediator of the inflammatory response to infection, and thus influence outcome. OBJECTIVE:To investigate the relationship between PCT, interleukin (IL)-10, tumor necrosis factor (TNF), organ failure, and mortality in pediatric septic shock...

journal_title：Critical care medicine

authors： Hatherill M,Tibby SM,Turner C,Ratnavel N,Murdoch IA

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:The emergency department (ED) often serves as the first site for the recognition and treatment of patients with suspected severe sepsis. However, few evaluations of the national epidemiology and distribution of severe sepsis in the ED exist. We sought to determine national estimates of the number, timing, ED ...

journal_title：Critical care medicine

authors： Wang HE,Shapiro NI,Angus DC,Yealy DM

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVES:Peripherally inserted central catheters are increasingly used in ICU as an alternative to centrally inserted central catheters for IV infusion. However, their reliability for hemodynamic measurements with transpulmonary thermodilution is currently unknown. We investigated the agreement between transpulmonary...

journal_title：Critical care medicine

authors： D'Arrigo S,Sandroni C,Cacciola S,Dell'Anna AM,Pittiruti M,Annetta MG,Colosimo C,Antonelli M

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVES:Chronic subdural hematoma is a commonly encountered disease in neurosurgic practice, whereas its increasing prevalence is compatible with the ageing population. Recommendations concerning postoperative thrombosis prophylaxis after burr-hole drainage of chronic subdural hematoma are lacking. The aim of this s...

journal_title：Critical care medicine

authors： Licci M,Kamenova M,Guzman R,Mariani L,Soleman J

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Granulocyte colony-stimulating factor is widely prescribed to hasten recovery from cancer chemotherapy-induced neutropenia and has been reported to induce pulmonary toxicity. However, circumstances and mechanisms of this toxicity remain poorly known. DESIGN:To reproduce a routine situation in cancer patients...

journal_title：Critical care medicine

authors： Azoulay E,Attalah H,Yang K,Jouault H,Schlemmer B,Brun-Buisson C,Brochard L,Harf A,Delclaux C

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:To investigate aortic functional alterations in the acute phase of aneurysmal subarachnoid hemorrhage and to evaluate the relationship between potential cardiovascular alterations and delayed cerebral infarctions or poor Glasgow Outcome Scale score at discharge from critical care unit. DESIGN:Prospective ob...

journal_title：Critical care medicine

authors： Papanikolaou J,Makris D,Karakitsos D,Saranteas T,Karabinis A,Kostopanagiotou G,Zakynthinos E

更新日期：2012-01-01 00:00:00

abstract：:Traumatic injuries occur in > 20 million children each year and are the leading source of death in children over the age of 1 yr. Mechanisms of injury and subsequent therapies for critically injured children are diverse. This review will focus on resources and management strategies for caring for the severely injured ...

journal_title：Critical care medicine

authors： White JR,Dalton HJ

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:This study evaluates the ability of perflubron to inhibit pulmonary neutrophil accumulation during partial liquid ventilation (PLV) in the setting of acute lung injury. DESIGN:Randomized, controlled, nonblinded study. SETTING:Research laboratory at a university. SUBJECTS:Male, Sprague-Dawley rats (n = 120,...

journal_title：Critical care medicine

authors： Colton DM,Till GO,Johnson KJ,Dean SB,Bartlett RH,Hirschl RB

更新日期：1998-10-01 00:00:00