Dose-related hemodynamic and renal effects of dopamine in septic shock.

abstract：OBJECTIVES:To compare the incidence of withdrawal or withholding of life support (WD/WHLS), and to identify similarities and differences in the process of the withdrawal of life support (WDLS) between teaching and community hospitals' intensive care units (ICUs). DESIGN:Prospective cohort study, with some data obtaine...

journal_title：Critical care medicine

authors： Keenan SP,Busche KD,Chen LM,Esmail R,Inman KJ,Sibbald WJ

更新日期：1998-02-01 00:00:00

abstract：:The objectives of this article were to review the causes and extent of hospital-associated infectious diarrhea and associated risks in the general hospital ward and intensive care unit (ICU), to compare microorganisms with similar symptoms to aid in recognition that will lead to timely and appropriate treatment and co...

journal_title：Critical care medicine

authors： Bobo LD,Dubberke ER

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Hemoglobin (Hb) induces vasoconstriction by heme group binding nitric oxide in an irreversible fashion. Recent in vitro studies indicate that the thiol groups in Hb reversibly bind nitric oxide and participate in trans-nitrosylation reactions with other thiols. Sepsis is a pathophysiologic state characterize...

journal_title：Critical care medicine

authors： Tejedor C,Lorente JA,Delgado MA,Fernández-Segoviano P,De Paula M,Tobalina R,Alonso M,Moscoso A,Soto F,Blázquez J,Esteban A

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:Very elderly persons admitted to ICUs are at high risk of death. To document life-sustaining interventions (mechanical ventilation, vasopressors, renal replacement therapy) provided in the ICU and outcomes of care. DESIGN:Multicenter, prospective cohort study. SETTING:ICUs of 24 Canadian hospitals. PARTICI...

journal_title：Critical care medicine

authors： Heyland D,Cook D,Bagshaw SM,Garland A,Stelfox HT,Mehta S,Dodek P,Kutsogiannis J,Burns K,Muscedere J,Turgeon AF,Fowler R,Jiang X,Day AG,Canadian Critical Care Trials Group.,Canadian Researchers at the End of Life Network.

更新日期：2015-07-01 00:00:00

abstract：:Critical decreases in oxygen delivery (DO2) and mixed venous oxygen saturation (SvO2) are associated with anaerobic metabolism and, therefore, lactic acidosis. We studied 50 consecutive patients with sepsis and 50 consecutive patients with acute myocardial infarction (AMI) in whom the arterial blood lactate was greate...

journal_title：Critical care medicine

authors： Astiz ME,Rackow EC,Kaufman B,Falk JL,Weil MH

更新日期：1988-07-01 00:00:00

abstract：:Estimations of blood glucose in the range 0-80 mg/dl were performed using the Chemstrip bG and StatTek Glucose Low Level test strips. Estimations of glucose levels closely approximated values obtained by a quantitative, enzymatic reference method; both appear to be excellent screening tests for hypoglycemia. There wer...

journal_title：Critical care medicine

authors： Maisels MJ,Lee CA

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVES:The mortality outcome of mechanical ventilation, a key intervention in the critically ill, has been variously reported to be determined by intensive care patient volume. We determined the volume-(mortality)-outcome relationship of mechanically ventilated patients whose records were contributed to the Austral...

journal_title：Critical care medicine

authors： Moran JL,Solomon PJ,ANZICS Centre for Outcome and Resource Evaluation of the Australian and New Zealand Intensive Care Society.

更新日期：2012-03-01 00:00:00

abstract：:The disciplines of critical care and palliative care may initially seem to be polar opposites, yet they share fundamental features. Both focus on the sickest patients in the healthcare system. Each discipline's primary goal-extending life for critical care and comfort and quality of life for palliative care-represents...

journal_title：Critical care medicine

authors： Byock I

更新日期：2006-11-01 00:00:00

abstract：:Bed rest is frequently prescribed for critically ill patients because it is assumed to be beneficial for preventing complications, for conserving scarce metabolic resources, and for providing patient comfort. Furthermore, higher levels of physical activity in critically ill patients have been assumed to be impractical...

journal_title：Critical care medicine

authors： Brower RG

更新日期：2009-10-01 00:00:00

abstract：:Clinically, asystole or a bradyarrhythmia may follow countershock of ventricular fibrillation (VF) in up to 40% of attempts. This study evaluated the effects of artificial cardiac pacing, calcium chloride (CaCl2), and epinephrine in postcountershock asystole/bradycardia. Micromanometer catheters were positioned in the...

journal_title：Critical care medicine

authors： Niemann JT,Adomian GE,Garner D,Rosborough JP

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:In the pathogenesis of disseminated intravascular coagulation, dysfunctional natural anticoagulant pathways appear to play a pivotal role. In this article, we will address the mechanisms that contribute to this defect in the regulation of coagulation activation. Furthermore, we will explore the experimental a...

journal_title：Critical care medicine

authors： Levi M,de Jonge E,van der Poll T

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:To determine bronchoalveolar lavage (BAL) fluid concentrations of keratinocyte growth factor (KGF) and hepatocyte growth factor (HGF), two potent growth factors for alveolar type II epithelial cells, in patients with acute respiratory distress syndrome (ARDS). DESIGN:Prospective study. SETTING:An adult tra...

journal_title：Critical care medicine

authors： Stern JB,Fierobe L,Paugam C,Rolland C,Dehoux M,Petiet A,Dombret MC,Mantz J,Aubier M,Crestani B

更新日期：2000-07-01 00:00:00

abstract：:The EEGs of 40 infants paralyzed with D-tubocurarine or pancuronium during the neonatal period were reviewed retrospectively. The 23 infants who survived were re-examined at 1-3 yr of age. Sixteen infants had normal or mildly abnormal EEGs in the neonatal period; 3 died of nonneurologic causes; the remainder were norm...

journal_title：Critical care medicine

authors： Tharp BR,Laboyrie PM

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVE:To investigate a role of the opiate system during acute hypoxic hypoxia, the effects of naloxone and morphine on hypoxic survival rate were investigated in awake adult mice. DESIGN:Prospective, randomized, animal trial. SETTING:University research laboratory. SUBJECTS:Male dd-Y mice (n = 864 in experiment ...

journal_title：Critical care medicine

authors： Endoh H,Taga K,Yamakura T,Sato K,Watanabe I,Fukuda S,Shimoji K

更新日期：1999-09-01 00:00:00

abstract：:The validity of the urinary urea nitrogen (UUN) estimate of total urinary nitrogen (TUN) was tested in patients who required iv nutrition. UUN and TUN were determined in 120 urine collections from ten preoperative, 13 postoperative, and 11 stressed patients. The relationship between TUN and UUN was examined by linear ...

journal_title：Critical care medicine

authors： Loder PB,Kee AJ,Horsburgh R,Jones M,Smith RC

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE:Levosimendan is a novel inodilator that improves cardiac contractility by sensitizing troponin C to calcium. This drug has proved to be effective in treating advanced congestive heart failure but has not been evaluated in septic settings. The purpose of the present study was to study the effects of this drug ...

journal_title：Critical care medicine

authors： Oldner A,Konrad D,Weitzberg E,Rudehill A,Rossi P,Wanecek M

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVES:To investigate aortic functional alterations in the acute phase of aneurysmal subarachnoid hemorrhage and to evaluate the relationship between potential cardiovascular alterations and delayed cerebral infarctions or poor Glasgow Outcome Scale score at discharge from critical care unit. DESIGN:Prospective ob...

journal_title：Critical care medicine

authors： Papanikolaou J,Makris D,Karakitsos D,Saranteas T,Karabinis A,Kostopanagiotou G,Zakynthinos E

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To determine whether base excess, base excess caused by unmeasured anions, and anion gap can predict lactate in adult critically ill patients, and also to determine whether acid-base variables can predict mortality in these patients. DESIGN:Retrospective study. SETTING:Adult intensive care unit of tertiary ...

journal_title：Critical care medicine

authors： Rocktaeschel J,Morimatsu H,Uchino S,Bellomo R

更新日期：2003-08-01 00:00:00

abstract：:The authors placed Swan-Ganz catheters in 11 preterm and 2 term infants with severe cardiopulmonary distress. The infants ranged in weight from 1100-4000 g. The procedure was performed in the neonatal ICU by jugular venous cutdown. Intracardiac pressures and oxygen saturations were measured in each chamber entered. Th...

journal_title：Critical care medicine

authors： Todres ID,Crone RK,Rogers MC,Shannon DC

更新日期：1979-08-01 00:00:00

abstract：OBJECTIVE:Acute lung injury secondary to smoke inhalation is a major source of morbidity and mortality in burn patients. We tested the hypothesis that nebulized epinephrine would ameliorate pulmonary dysfunction secondary to acute lung injury by reducing airway hyperemia and edema formation and mediating bronchodilatat...

journal_title：Critical care medicine

authors： Lange M,Hamahata A,Traber DL,Cox RA,Kulp GA,Nakano Y,Traber LD,Herndon DN,Enkhbaatar P

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Prevalence and causes of sex-based differences in morbidity and mortality secondary to cardiovascular disease remain controversial. Cardiac troponin I (cTnI) is a sensitive and specific marker for myocardial injury. Serial cTnI measurements have been used to identify perioperative myocardial cell injury. OB...

journal_title：Critical care medicine

authors： Schwarzenberger JC,Sun LS,Pesce MA,Heyer EJ,Delphin E,Almeida GM,Wood M

更新日期：2003-03-01 00:00:00

abstract：:One hundred patients were ventilated with high-frequency jet ventilation (HFJV) during the initial 24-h postoperative period in the surgical and neurosurgical ICUs. Eighty-three were successfully weaned, 2 could not be ventilated adequately with HFJV, and 15 with criteria of acute respiratory failure received HFJV for...

journal_title：Critical care medicine

authors： Sladen A,Guntupalli K,Marquez J,Klain M

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:Cocaine, which first made its appearance >1,000 yrs ago, is now widely used throughout the world. The physiologic responses to cocaine may cause severe pathologic effects. This review highlights the many critical care challenges resulting from these effects. DESIGN:Historical vignettes, epidemiologic factors...

journal_title：Critical care medicine

authors： Shanti CM,Lucas CE

更新日期：2003-06-01 00:00:00

abstract：:Among Gram-positive pathogens, Staphylococcus aureus is the leading cause of death from nosocomial pneumonia. The bacterium developed progressive resistance to beta-lactams, and methicillin-resistant strains emerged in the 1980s. In consequence, vancomycin has become the drug of choice for treatment of this infection ...

journal_title：Critical care medicine

authors： Bodi M,Ardanuy C,Rello J

更新日期：2001-04-01 00:00:00

abstract：:We previously reported that small volume infusions of 7.5% NaCl in 6% dextran-70 (HSD) are superior to equal volumes of normal saline (NS) or 7.5% NaCl in the ability to resuscitate animals from an otherwise lethal hemorrhage. In the present experiment, we evaluated organ blood flow in unanesthetized swine bled 46 ml/...

journal_title：Critical care medicine

authors： Maningas PA

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVES:Although studies have indicated that adrenal insufficiency occurs after severe trauma and hemorrhagic shock, it remains controversial whether adrenal function is depressed during the late stage of polymicrobial sepsis. DESIGN:Prospective, controlled animal study. SETTING:A university research laboratory. ...

journal_title：Critical care medicine

authors： Koo DJ,Jackman D,Chaudry IH,Wang P

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:To compare the effectiveness and safety of the hemoglobin-based nitric oxide scavenger, pyridoxalated hemoglobin polyoxyethylene, against placebo in patients with vasopressor-dependent distributive shock. DESIGN:Multicenter, randomized, placebo-controlled, open-label study. SETTING:Sixty-one participating I...

journal_title：Critical care medicine

authors： Vincent JL,Privalle CT,Singer M,Lorente JA,Boehm E,Meier-Hellmann A,Darius H,Ferrer R,Sirvent JM,Marx G,DeAngelo J

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:To determine whether aerosolized antibiotics can be delivered efficiently to the lower respiratory tract in mechanically ventilated patients and to define possible clinical responses to these agents. DESIGN:Prospective serial study with cases as their own control. SETTING:A 10-bed respiratory care unit for...

journal_title：Critical care medicine

authors： Palmer LB,Smaldone GC,Simon SR,O'Riordan TG,Cuccia A

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVES:To explore the effects of dobutamine and norepinephrine on the global cardiovascular response and on the relationship between oxygen uptake (VO2) and oxygen delivery (DO2) during an acute reduction in blood flow associated with tamponade. DESIGN:Prospective, randomized, controlled acute intervention study. ...

journal_title：Critical care medicine

authors： Zhang H,Spapen H,Vincent JL

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:This report will describe the preparations for and the provision of care of two patients with Ebola virus disease in the biocontainment unit at the University of Nebraska Medical Center. DATA SOURCES:Patient medical records. STUDY SELECTION:Not applicable. DATA EXTRACTION:Not applicable. DATA SYNTHESIS:No...

journal_title：Critical care medicine

authors： Johnson DW,Sullivan JN,Piquette CA,Hewlett AL,Bailey KL,Smith PW,Kalil AC,Lisco SJ

更新日期：2015-06-01 00:00:00