Validity of urinary urea nitrogen as a measure of total urinary nitrogen in adult patients requiring parenteral nutrition.

abstract：OBJECTIVE:Cortisol clearance is reduced in sepsis and may contribute to the development of impaired adrenocortical function that is thought to contribute to the pathophysiology of critical illness-related corticosteroid insufficiency. We sought to assess adrenocortical function using computer-assisted numerical modelin...

journal_title：Critical care medicine

authors： Dorin RI,Qualls CR,Torpy DJ,Schrader RM,Urban FK 3rd

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:To evaluate the use of multifrequency bioelectrical impedance analysis to predict creatinine/urea clearance based on 24 hours urine collection. A practical formula was developed, and its performance was compared with that of established formulas such as Cockcroft-Gault, Modification of Diet in Renal Disease,...

journal_title：Critical care medicine

authors： de Jong LAA,Otten-Helmers AG,Spronk PE,van Kan HJM

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:Spread of multidrug-resistant organisms within the intensive care unit (ICU) results in substantial morbidity and mortality. Novel strategies are needed to reduce transmission. This study sought to determine if the use of daily chlorhexidine bathing would decrease the incidence of colonization and bloodstream...

journal_title：Critical care medicine

authors： Climo MW,Sepkowitz KA,Zuccotti G,Fraser VJ,Warren DK,Perl TM,Speck K,Jernigan JA,Robles JR,Wong ES

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:Bag-mask ventilation is commonly used prior to tracheal intubation; however, the epidemiology, risk factors, and clinical implications of difficult bag-mask ventilation among critically ill children are not well studied. This study aims to describe prevalence and risk factors for pediatric difficult bag-mask...

journal_title：Critical care medicine

authors： Daigle CH,Fiadjoe JE,Laverriere EK,Bruins BB,Lockman JL,Shults J,Krawiec C,Harwayne-Gidansky I,Page-Goertz C,Furlong-Dillard J,Nadkarni VM,Nishisaki A,National Emergency Airway Registry for Children (NEAR4KIDS) Investigators and

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:The impact of recruitment maneuvers on gas exchange, hemodynamics, alveolar recruitment, and hyperinflation is highly variable among patients with acute respiratory distress syndrome. The objective was to determine whether differences in lung morphology, defined as differences in the pulmonary distribution o...

journal_title：Critical care medicine

authors： Constantin JM,Grasso S,Chanques G,Aufort S,Futier E,Sebbane M,Jung B,Gallix B,Bazin JE,Rouby JJ,Jaber S

更新日期：2010-04-01 00:00:00

abstract：RATIONALE:Life and death triage decisions are made daily by intensive care unit physicians. Admission to an intensive care unit is denied when intensive care unit resources are constrained, especially for the elderly. OBJECTIVE:To determine the effect of intensive care unit triage decisions on mortality and intensive ...

journal_title：Critical care medicine

authors： Sprung CL,Artigas A,Kesecioglu J,Pezzi A,Wiis J,Pirracchio R,Baras M,Edbrooke DL,Pesenti A,Bakker J,Hargreaves C,Gurman G,Cohen SL,Lippert A,Payen D,Corbella D,Iapichino G

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:The objectives of this article are to introduce and explore a novel paradigm based on complex nonlinear systems, and to evaluate its application to critical care research regarding the systemic host response and multiple organ dysfunction syndrome (MODS). DATA SOURCES:Published original work, review article...

journal_title：Critical care medicine

authors： Seely AJ,Christou NV

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Nutritional support is an essential component of the management of critically ill and injured ICU patients. Optimal provision of calories and protein has been demonstrated to reduce morbidity, mortally, and length of ICU and hospital stay. Yet, a large proportion of ICU patients receive inadequate nutrition....

journal_title：Critical care medicine

authors： Marik PE

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:Increases in exhaled nitric oxide have been demonstrated to originate from the lungs of rats after septic lung injury. The aim of this study was to investigate whether treatment with the nitric oxide synthase inhibitor N-nitro-L-arginine methyl ester (L-NAME) would prevent lipopolysaccharide (LPS)-induced in...

journal_title：Critical care medicine

authors： Aaron SD,Valenza F,Volgyesi G,Mullen JB,Slutsky AS,Stewart TE

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:To describe the long-term health-related quality of life (HRQL) of survivors of sepsis and to evaluate the reliability and validity of the medical outcomes study Short Form-36 (SF-36) in this population. STUDY DESIGN:Cross-sectional survey. SETTING:University intensive care unit. PATIENTS:Surviving patient...

journal_title：Critical care medicine

authors： Heyland DK,Hopman W,Coo H,Tranmer J,McColl MA

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To compare silver-coated and uncoated central venous catheters regarding bacterial colonization. To assess the relative contribution of catheter hub and skin colonization to catheter tip colonization. DESIGN:Prospective, randomized clinical trial. SETTING:Intensive care unit in a university hospital. PATIE...

journal_title：Critical care medicine

authors： Bach A,Eberhardt H,Frick A,Schmidt H,Böttiger BW,Martin E

更新日期：1999-03-01 00:00:00

abstract：:An 8-yr-old child suffered traumatic bilateral pneumothoraces and a ruptured right main bronchus. Surgical repair of the bronchus was postponed for 18 h after a definite diagnosis was established due to severe hypoxemia and hypercarbia. Only left endobronchial high-frequency ventilation with muscle relaxation correcte...

journal_title：Critical care medicine

authors： Pizov R,Shir Y,Eimerl D,Uretzky G,Milgalter E,Cotev S

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE:To systematically investigate the effect of altering release time during airway pressure release ventilation in a neonatal animal model before and after oleic acid-induced acute lung injury. DESIGN:Prospective, nonrandomized, controlled study with repeated measures. SETTING:University research laboratory. ...

journal_title：Critical care medicine

authors： Martin LD,Wetzel RC

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Pneumonia accounts for almost half of intensive care unit (ICU) infections and nearly 60% of deaths from nosocomial infections. It increases hospital stay by 7-9 days, crude mortality by 70% and attributable mortality by 30%. OBJECTIVE:Our purpose was to assess the impact of standard operating procedures ad...

journal_title：Critical care medicine

authors： Nachtigall I,Tamarkin A,Tafelski S,Deja M,Halle E,Gastmeier P,Wernecke KD,Bauer T,Kastrup M,Spies C

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To describe the philosophy and approach to patient care called evidence based medicine, and to highlight how it can enhance the practice of intensive care. DATA SOURCES:We searched MEDLINE, reference lists, and our personal files to identify relevant literature. STUDY SELECTION:Articles on intensive care pr...

journal_title：Critical care medicine

authors： Cook DJ,Sibbald WJ,Vincent JL,Cerra FB

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:To investigate whether a redistribution of blood flow from the mucosa to the muscular layer of the intestinal wall contributes to the observed increased arterial-mucosal Pco2 gradient and the decreased mucosal tonometric pH during endotoxic shock. DESIGN:A prospective, controlled, animal study. SETTING:Anim...

journal_title：Critical care medicine

authors： Revelly JP,Ayuse T,Brienza N,Fessler HE,Robotham JL

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:Transfusion of red blood cells has been linked to disappointing clinical outcomes in the critically ill, but specific mechanisms of organ dysfunction after transfusion remain poorly understood. We tested the hypothesis that red blood cell storage impairs the ability of red blood cells to release adenosine-5'-...

journal_title：Critical care medicine

authors： Zhu H,Zennadi R,Xu BX,Eu JP,Torok JA,Telen MJ,McMahon TJ

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Hemorrhage in trauma is a significant challenge, accounting for 30% to 40% of all fatalities, second only to central nervous system injury as a cause of death. However, hemorrhagic death is the leading preventable cause of mortality in combat casualties and typically occurs within 6 to 24 hrs of injury. In c...

journal_title：Critical care medicine

authors： Perkins JG,Cap AP,Weiss BM,Reid TJ,Bolan CD

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To study the course of gastric regional PCO2 (PrCO2) in patients with cardiogenic shock requiring intra-aortic balloon (IAB) counterpulsation and the prognostic value of PrCO2 in this patient population. DESIGN:A prospective, observational clinical study. SETTING:Medical intensive care unit in a university ...

journal_title：Critical care medicine

authors： Janssens U,Graf J,Koch KC,vom Dahl J,Hanrath P

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND AND METHODS:In the present study, we evaluated the effect of N-acetylcysteine treatment in a nonseptic shock model induced by zymosan in the rat. Animals were randomly divided into eight groups (ten animals in each group). The first group was treated with ip administration of saline solution (0.90% NaCl) and...

journal_title：Critical care medicine

authors： Cuzzocrea S,Costantino G,Mazzon E,Caputi AP

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:Patients with severe sepsis have high mortality that is improved by timely, often expensive, treatments. Patients without insurance are more likely to delay seeking care; they may also receive less intense care. DESIGN:We performed a retrospective analysis of administrative database-Healthcare Costs and Util...

journal_title：Critical care medicine

authors： Kumar G,Taneja A,Majumdar T,Jacobs ER,Whittle J,Nanchal R,Milwaukee Initiative in Critical Care Outcomes Research (MICCOR) Group of Investigators.

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:To characterize the rates of accidental removal of endotracheal tubes, nasogastric tubes, central venous catheters, and arterial catheters. To assess the efficacy of corrective measures aimed at reducing the accidental removal of these devices. DESIGN:Prospective, observational, and interventional study. S...

journal_title：Critical care medicine

authors： Carrión MI,Ayuso D,Marcos M,Paz Robles M,de la Cal MA,Alía I,Esteban A

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of lorazepam and midazolam for long-term sedation of critically ill, mechanically ventilated patients. DESIGN:Double-blind, randomized, controlled study. SETTING:Medical intensive care unit in a university teaching hospital. PATIENTS:Sixty-four evaluable adult patients admitte...

journal_title：Critical care medicine

authors： Swart EL,van Schijndel RJ,van Loenen AC,Thijs LG

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVES:To compare sleep, work hours, and behavioral alertness in faculty and fellows during a randomized trial of nighttime in-hospital intensivist staffing compared with a standard daytime intensivist model. DESIGN:Prospective observational study. SETTING:Medical ICU of a tertiary care academic medical center du...

journal_title：Critical care medicine

authors： Bakhru RN,Basner M,Kerlin MP,Halpern SD,Hansen-Flaschen J,Rosen IM,Dinges DF,Schweickert WD

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:The high incidence of lower lobe collapse in adult intensive care patients is well described. We aimed to document the incidence and distribution of acute lobar collapse in the pediatric intensive care setting. The influence of anatomical and pathophysiological differences between the adult and pediatric resp...

journal_title：Critical care medicine

authors： Thomas K,Habibi P,Britto J,Owens CM

更新日期：1999-08-01 00:00:00

abstract：:Last year, >28,000 people received organ transplants from >14,000 donors in the United States. Unfortunately, the wait list now tops 91,000, with the gap between recipient needs and available donor organs at around 60,000. This has motivated a host of efforts to increase organ supply, including driver's license and do...

journal_title：Critical care medicine

authors： Aulisio MP,Devita M,Luebke D

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:To assess survival after cardiac arrest and to determine whether age is an independent determinant of late mortality or poor neurologic outcome. DESIGN:Analyses using results of Brain Resuscitation Clinical Trial I (1979 to 1984) and Brain Resuscitation Clinical Trial II (1984 to 1989), two randomized, doubl...

journal_title：Critical care medicine

authors： Rogove HJ,Safar P,Sutton-Tyrrell K,Abramson NS

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:To determine risk factors for nosocomial pneumonia in critically ill trauma patients. DESIGN:Prospective cohort study. SETTING:The trauma intensive care unit (ICU) of a 1500-bed tertiary-care hospital. PATIENTS:All critically ill trauma patients (n = 103) admitted consecutively between November 1995 and Oc...

journal_title：Critical care medicine

authors： Tejada Artigas A,Bello Dronda S,Chacón Vallés E,Muñoz Marco J,Villuendas Usón MC,Figueras P,Suarez FJ,Hernández A

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:To investigate the concentrations of reduced and total glutathione in relation to the muscle free amino acid pattern in critically ill patients and matched healthy controls. DESIGN:Prospective case control. SETTING:University hospital intensive care unit (ICU). PATIENTS:Eleven critically ill patients in th...

journal_title：Critical care medicine

authors： Hammarqvist F,Luo JL,Cotgreave IA,Andersson K,Wernerman J

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:Within minutes of reperfusing ischemic cardiomyocytes, oxidant stress dramatically increases and is associated with postresuscitation injury. Because mitochondria produce deleterious oxidants and useful metabolic substrates, utilization of electron transport chain inhibitors against reperfusion injury, though...

journal_title：Critical care medicine

authors： Anderson TC,Li CQ,Shao ZH,Hoang T,Chan KC,Hamann KJ,Becker LB,Vanden Hoek TL

更新日期：2006-12-01 00:00:00