Enteral nutrition in the critically ill: myths and misconceptions.

abstract：OBJECTIVE:The requirement for a blood transfusion after trauma is associated with an increased risk of acute lung injury. Residual leukocytes contaminating red cells are potential mediators of this syndrome. The goal of this trial was to test our hypothesis that prestorage leukoreduction of blood would reduce rates of ...

journal_title：Critical care medicine

authors： Watkins TR,Rubenfeld GD,Martin TR,Nester TA,Caldwell E,Billgren J,Ruzinski J,Nathens AB

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To determine the frequency and effects of weaning-related myocardial ischemia on weaning outcomes in patients with coronary artery disease. DESIGN:Prospective cohort study. SETTING:Medical and cardiac intensive care units of a 300-bed teaching community hospital. MEASUREMENTS AND MAIN RESULTS:Three-lead ST...

journal_title：Critical care medicine

authors： Srivastava S,Chatila W,Amoateng-Adjepong Y,Kanagasegar S,Jacob B,Zarich S,Manthous CA

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVES:This study was designed to assess the effects on macrocirculation and microcirculation of adding an intra-aortic balloon pump to peripheral venoarterial extracorporeal membrane oxygenation in patients with severe cardiogenic shock and little/no residual left ventricular ejection. DESIGN:A prospective, singl...

journal_title：Critical care medicine

authors： Petroni T,Harrois A,Amour J,Lebreton G,Brechot N,Tanaka S,Luyt CE,Trouillet JL,Chastre J,Leprince P,Duranteau J,Combes A

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To determine whether a correlation exists between concentrations of intracellular and extracellular potassium and to determine the frequency of ventricular ectopy in patients after cardiac operations. DESIGN:Prospective, observational clinical evaluation. SETTING:Surgical-respiratory intensive care unit of ...

journal_title：Critical care medicine

authors： Johnson RG,Shafique T,Sirois C,Weintraub RM,Comunale ME

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:Increasing evidence, including publication of the Transfusion Requirements in Critical Care trial in 1999, supports a lower hemoglobin threshold for RBC transfusion in ICU patients. However, little is known regarding the influence of this evidence on clinical practice over time in a large population-based coh...

journal_title：Critical care medicine

authors： Murphy DJ,Needham DM,Netzer G,Zeger SL,Colantuoni E,Ness P,Pronovost PJ,Berenholtz SM

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:Pneumothorax is a frequent complication during mechanical ventilation. Electrical impedance tomography (EIT) is a noninvasive tool that allows real-time imaging of regional ventilation. The purpose of this study was to 1) identify characteristic changes in the EIT signals associated with pneumothoraces; 2) d...

journal_title：Critical care medicine

authors： Costa EL,Chaves CN,Gomes S,Beraldo MA,Volpe MS,Tucci MR,Schettino IA,Bohm SH,Carvalho CR,Tanaka H,Lima RG,Amato MB

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:Granulocyte transfusions have been used to treat immune cell dysfunction in sepsis. As granulocyte transfusions can trigger tissue injury via local effects of neutrophils, we hypothesized that extracorporeal treatment of plasma using granulocytes would prove beneficial while having less side effects. DESIGN...

journal_title：Critical care medicine

authors： Sauer M,Altrichter J,Kreutzer HJ,Lögters T,Scholz M,Nöldge-Schomburg G,Schmidt R,Mitzner SR

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:In 1991, the American College of Chest Physicians (ACCP) and the Society of Critical Care Medicine (SCCM) convened a "Consensus Conference," the goals of which were "to provide a conceptual and a practical framework to define the systemic inflammatory response to infection, which is a progressive injurious pr...

journal_title：Critical care medicine

authors： Levy MM,Fink MP,Marshall JC,Abraham E,Angus D,Cook D,Cohen J,Opal SM,Vincent JL,Ramsay G,SCCM\/ESICM\/ACCP\/ATS\/SIS.

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:To evaluate the internal consistency, validity, responsiveness, and minimal important difference of the Functional Status Score for the ICU, a physical function measure designed for the ICU. DESIGN:Clinimetric analysis. SETTINGS:Five international datasets from the United States, Australia, and Brazil. PA...

journal_title：Critical care medicine

authors： Huang M,Chan KS,Zanni JM,Parry SM,Neto SG,Neto JA,da Silva VZ,Kho ME,Needham DM

更新日期：2016-12-01 00:00:00

abstract：:Last year, >28,000 people received organ transplants from >14,000 donors in the United States. Unfortunately, the wait list now tops 91,000, with the gap between recipient needs and available donor organs at around 60,000. This has motivated a host of efforts to increase organ supply, including driver's license and do...

journal_title：Critical care medicine

authors： Aulisio MP,Devita M,Luebke D

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:To determine whether peptic activity in bronchoalveolar fluid, due to the presence of the gastric proteolytic enzyme pepsin, could serve as a biochemical marker for pulmonary aspiration of gastric contents. DESIGN:Prospective, experimental trial. SETTING:A university animal research laboratory. SUBJECTS:Th...

journal_title：Critical care medicine

authors： Badellino MM,Buckman RF Jr,Malaspina PJ,Eynon CA,O'Brien GM,Kueppers F

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVES:Our goal was to "reverse translate" the human response to surgical sepsis into the mouse by modifying a widely adopted murine intra-abdominal sepsis model to engender a phenotype that conforms to current sepsis definitions and follows the most recent expert recommendations for animal preclinical sepsis resea...

journal_title：Critical care medicine

authors： Stortz JA,Hollen MK,Nacionales DC,Horiguchi H,Ungaro R,Dirain ML,Wang Z,Wu Q,Wu KK,Kumar A,Foster TC,Stewart BD,Ross JA,Segal M,Bihorac A,Brakenridge S,Moore FA,Wohlgemuth SE,Leeuwenburgh C,Mohr AM,Moldawer LL,E

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:Reviews of patient safety efforts suggest that technical/administrative change must be augmented by global factors such as organizational culture and climate. The objective was to outline a comprehensive model for healthcare climate and test one of its elements, the nursing subclimate, in terms of several pa...

journal_title：Critical care medicine

authors： Zohar D,Livne Y,Tenne-Gazit O,Admi H,Donchin Y

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:Unplanned readmission of hospitalized patients to an intensive care unit (ICU) is associated with a worse outcome, but our ability to identify who is likely to deteriorate after ICU dismissal is limited. The objective of this study is to develop and validate a numerical index, named the Stability and Workload...

journal_title：Critical care medicine

authors： Gajic O,Malinchoc M,Comfere TB,Harris MR,Achouiti A,Yilmaz M,Schultz MJ,Hubmayr RD,Afessa B,Farmer JC

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Increased intracranial pressure (ICP) worsens the outcome of acute liver failure (ALF). This study investigates the underlying pathophysiological mechanisms and evaluates the therapeutic effect of albumin dialysis in ALF with use of the Molecular Adsorbents Recirculating System without hemofiltration/dialysi...

journal_title：Critical care medicine

authors： Sen S,Rose C,Ytrebø LM,Davies NA,Nedredal GI,Drevland SS,Kjønnø M,Prinzen FW,Hodges SJ,Deutz NE,Williams R,Butterworth RF,Revhaug A,Jalan R

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:To systematically investigate the effect of altering release time during airway pressure release ventilation in a neonatal animal model before and after oleic acid-induced acute lung injury. DESIGN:Prospective, nonrandomized, controlled study with repeated measures. SETTING:University research laboratory. ...

journal_title：Critical care medicine

authors： Martin LD,Wetzel RC

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:To investigate glycemic dynamics and its relation with mortality in critically ill patients. We searched for differences in complexity of the glycemic profile between survivors and nonsurvivors in patients admitted to a multidisciplinary intensive care unit. DESIGN:Prospective, observational study, convenien...

journal_title：Critical care medicine

authors： Lundelin K,Vigil L,Bua S,Gomez-Mestre I,Honrubia T,Varela M

更新日期：2010-03-01 00:00:00

abstract：:The definition of sepsis has been recently modified to accommodate emerging knowledge in the field, while at the same time being recognized as challenging, if not impossible, to define. Here, we seek to clarify the current understanding of sepsis as one that has been typically framed as a disorder of inflammation to o...

journal_title：Critical care medicine

authors： Alverdy JC,Krezalek MA

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:Acinetobacter baumannii complex bacteremia has been identified increasingly in critical patients admitted in ICUs. Notably, A. baumannii complex bacteremia has a high mortality rate, yet the risk factors associated with mortality remain unclear and controversial. DESIGN:Retrospective study. SETTING:All adu...

journal_title：Critical care medicine

authors： Lee HY,Chen CL,Wu SR,Huang CW,Chiu CH

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To cost adult intensive care by determining inputs to production, resource consumption per patient, and total cost per intensive care unit (ICU) stay. DESIGN:Prospective cost-accounting analysis of each patient stay in the ICU, over a 1-yr period. SETTING:An 11-bed, medical/surgical adult ICU, in a 932-bad ...

journal_title：Critical care medicine

authors： Noseworthy TW,Konopad E,Shustack A,Johnston R,Grace M

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:To describe a case of hepatic subcapsular hematoma causing an acute Budd-Chiari-like syndrome, leading to hepatic compartment syndrome, which combines compression of intrahepatic vessels on CT, acute liver failure, and refractory shock. DESIGN:Case report. SETTING:Surgical ICU of a university teaching hospi...

journal_title：Critical care medicine

authors： Marcaire F,Malavieille F,Pichot-Delahaye V,Floccard B,Rimmelé T

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:a) To determine whether pentoxifylline has a preventive effect on the decrease in PaO2 that is caused by oleic acid, and whether pentoxifylline facilitates normalization of PaO2 from the decreased state. b) To examine whether pentoxifylline can attenuate an increase in pulmonary vascular permeability that is...

journal_title：Critical care medicine

authors： Moriuchi H,Yuizono T

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVES:To describe the most common serious adverse effects and organ toxicities associated with emerging therapies for cancer that may necessitate admission to the ICU. DATA SOURCES AND STUDY SELECTION:PubMed and Medline search of relevant articles in English on the management of adverse effects of immunotherapy f...

journal_title：Critical care medicine

authors： Gutierrez C,McEvoy C,Munshi L,Stephens RS,Detsky ME,Nates JL,Pastores SM

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of the technique of selective decontamination of the digestive tract in preventing the development of secondary infection and its influence on morbidity and mortality rates in multiple trauma patients with chest injuries requiring intermittent positive-pressure ventilation. DESIGN:Pr...

journal_title：Critical care medicine

authors： Hammond JM,Potgieter PD,Saunders GL

更新日期：1994-01-01 00:00:00

abstract：:Thirty-three patients underwent extensive cardiorespiratory monitoring during cardiac surgery. Recordings of measurements, with derived variables, were made preoperatively, postoperatively, and after extubation approximately 3 h after operation. The data provide a reference that allows decisions on whether the conditi...

journal_title：Critical care medicine

authors： Prakash O,Meij S,v d Borden B,Saxena PR

更新日期：1981-07-01 00:00:00

abstract：OBJECTIVE:This study determined the time course for inhibition of lipopolysaccharide-induced acute lung injury following a single dose of genistein. In addition, the study investigated whether a multiple dosing schedule with genistein retained the inhibitory effects on acute lung injury, nuclear factor-kappaB activatio...

journal_title：Critical care medicine

authors： Kang JL,Lee HW,Lee HS,Pack IS,Castranova V,Koh Y

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To compare and evaluate the potential benefit of two different anticoagulation regimens during endotoxemia in an ovine model. DESIGN:Animal prospective randomized and controlled study following preliminary dose-range study conforming with the Guide for the Care and Use of Laboratory Animals as promulgated by...

journal_title：Critical care medicine

authors： Schiffer ER,Reber G,De Moerloose P,Morel DR

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVES:We reviewed randomized trials of adult ICU patients of interventions hypothesized to reduce delirium burden to determine whether interventions that are more effective at reducing delirium duration are associated with a reduction in short-term mortality. DATA SOURCES:We searched CINHAHL, EMBASE, MEDLINE, and...

journal_title：Critical care medicine

authors： Al-Qadheeb NS,Balk EM,Fraser GL,Skrobik Y,Riker RR,Kress JP,Whitehead S,Devlin JW

更新日期：2014-06-01 00:00:00

abstract：:Prolonged therapeutic paralysis with pancuronium is commonly used in ICUs to facilitate mechanical ventilation of patients with respiratory failure. Sedation is usually given concomitantly to reduce patient discomfort, but assessment of its adequacy is made difficult by the paralysis. We recently cared for a former IC...

journal_title：Critical care medicine

authors： Parker MM,Schubert W,Shelhamer JH,Parrillo JE

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that PaCO2 levels generated during permissive hypercapnia may enhance arterial oxygenation, when ventilation is maintained. DESIGN:Prospective study. SETTING:Research laboratory in a hospital. SUBJECTS:One group of eight mongrel dogs (four male; four female). INTERVENTIONS:The dogs ...

journal_title：Critical care medicine

authors： Torbati D,Mangino MJ,Garcia E,Estrada M,Totapally BR,Wolfsdorf J

更新日期：1998-11-01 00:00:00