Evaluation of unfractionated heparin and recombinant hirudin on survival in a sustained ovine endotoxin shock model.

abstract：OBJECTIVES:To evaluate the frequency of unsuspected posterior vessel wall penetration of the internal jugular vein during ultrasound-guided needle cannulation. DESIGN:Prospective, single-blinded observational study. SETTING:Urban level I emergency department with an annual census of 80,000. PATIENTS:Residents who ha...

journal_title：Critical care medicine

authors： Blaivas M,Adhikari S

更新日期：2009-08-01 00:00:00

abstract：:An 8-yr-old child suffered traumatic bilateral pneumothoraces and a ruptured right main bronchus. Surgical repair of the bronchus was postponed for 18 h after a definite diagnosis was established due to severe hypoxemia and hypercarbia. Only left endobronchial high-frequency ventilation with muscle relaxation correcte...

journal_title：Critical care medicine

authors： Pizov R,Shir Y,Eimerl D,Uretzky G,Milgalter E,Cotev S

更新日期：1987-12-01 00:00:00

abstract：:We evaluated 95 extubated neonates to determine if certain risk factors could predict the development of laryngeal injury. Risk factors were recorded prospectively during the intubation period and correlated with laryngeal injury determined by laryngoscopy after extubation. Duration of intubation greater than or equal...

journal_title：Critical care medicine

authors： Fan LL,Flynn JW,Pathak DR

更新日期：1983-06-01 00:00:00

abstract：:In the last three decades, numerous articles on plasma catecholamine concentrations in various settings have been published in the medical literature. Despite this abundance of information, no summary article has analyzed the species variations in circulating catecholamine concentrations. In this paper, the plasma cat...

journal_title：Critical care medicine

authors： Hart BB,Stanford GG,Ziegler MG,Lake CR,Chernow B

更新日期：1989-11-01 00:00:00

abstract：:Reproducibility of thermal-dye extravascular lung water (EVLW) estimation by a lung water computer was studied by performing ten consecutive measurements in 45 critically ill patients. EVLW ranged over a wide spectrum from 187 to 1163 ml (2.4 to 18.6 ml/kg). The mean coefficient of variation of ten consecutive measure...

journal_title：Critical care medicine

authors： Laggner AN,Lenz K,Druml W,Kleinberger G

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVE:Granulocyte colony-stimulating factor is widely prescribed to hasten recovery from cancer chemotherapy-induced neutropenia and has been reported to induce pulmonary toxicity. However, circumstances and mechanisms of this toxicity remain poorly known. DESIGN:To reproduce a routine situation in cancer patients...

journal_title：Critical care medicine

authors： Azoulay E,Attalah H,Yang K,Jouault H,Schlemmer B,Brun-Buisson C,Brochard L,Harf A,Delclaux C

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the role of cholesterol and lipoproteins in children with severe meningococcal sepsis. DESIGN:Retrospective observational study. SETTING:A university-affiliated pediatric intensive care unit. PATIENTS:Fifty-seven patients admitted to the pediatric intensive care unit with meningococcal sepsis o...

journal_title：Critical care medicine

authors： Vermont CL,den Brinker M,Kâkeci N,de Kleijn ED,de Rijke YB,Joosten KF,de Groot R,Hazelzet JA

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To investigate a role of the opiate system during acute hypoxic hypoxia, the effects of naloxone and morphine on hypoxic survival rate were investigated in awake adult mice. DESIGN:Prospective, randomized, animal trial. SETTING:University research laboratory. SUBJECTS:Male dd-Y mice (n = 864 in experiment ...

journal_title：Critical care medicine

authors： Endoh H,Taga K,Yamakura T,Sato K,Watanabe I,Fukuda S,Shimoji K

更新日期：1999-09-01 00:00:00

abstract：:Healthcare systems spend considerable resources collecting and processing blood cultures for the detection of blood stream pathogens. The process is initiated with the collection of blood cultures that depend upon proper skin disinfection, collection of an adequate number of specimens and volume of blood, and prompt p...

journal_title：Critical care medicine

authors： Murray PR,Masur H

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Persistent pulmonary hypertension of the newborn is characterized by the presence of intense vasoconstriction and vascular remodeling. Protein tyrosine phosphorylation has been recognized as a critical regulatory element in signal transduction, because it is dynamically regulated by the opposing actions of pr...

journal_title：Critical care medicine

authors： Berkenbosch JW,Baribeau J,Ferretti E,Perreault T

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:Although the development of ventilator-associated pneumonia (VAP) is assumed to increase costs of intensive care unit stay, it is unknown whether prevention of VAP by means of oropharyngeal decontamination is cost-effective. Because of wide ranges of individual patient costs, crude cost comparisons did not sh...

journal_title：Critical care medicine

authors： van Nieuwenhoven CA,Buskens E,Bergmans DC,van Tiel FH,Ramsay G,Bonten MJ

更新日期：2004-01-01 00:00:00

abstract：:The venous-arterial PCO2 gradient may increase in certain low-flow states, such as CPR and canine endotoxemia. To determine whether venous hypercarbia also occurs in hemorrhagic shock, we studied 12 anesthetized, mechanically ventilated dogs. We performed laparotomies on the animals, inserting catheters into their ren...

journal_title：Critical care medicine

authors： Benjamin E,Paluch TA,Berger SR,Premus G,Wu C,Iberti TJ

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:We sought to investigate if the chloride content of fluids used in resuscitation was associated with short- and long-term outcomes. DESIGN:We identified patients who received large-volume fluid resuscitation, defined as greater than 60 mL/kg over a 24-hour period. Chloride load was determined for each patien...

journal_title：Critical care medicine

authors： Sen A,Keener CM,Sileanu FE,Foldes E,Clermont G,Murugan R,Kellum JA

更新日期：2017-02-01 00:00:00

abstract：:The Hemoccult slide test is used frequently to test for the presence of occult blood in samples of gastric juice obtained from critically ill patients. The purpose of this study was to investigate the accuracy of this test to determine the presence of blood in human gastric juice at various pH values. Gastric aspirate...

journal_title：Critical care medicine

authors： Long PC,Wilentz KV,Sudlow G,Skillman JJ

更新日期：1982-10-01 00:00:00

abstract：:This report is intended to familiarize the reader with the current legislation concerning state definitions of death, the pertinent judicial decisions concerning termination of life support and the current status of medical/ethical committees. However, it is of paramount importance to all health care personnel to beco...

journal_title：Critical care medicine

authors： Wallace-Barnhill G,Roth MD,Briggs BA,Bastron DR,Barrocas A

更新日期：1982-01-01 00:00:00

abstract：:The care of critically ill children has become more complex and demanding. This document establishes recommendations for developing regionalized integration of the care of these children into the emergency medical services system. These recommendations were developed by pediatricians with expertise in pediatric critic...

journal_title：Critical care medicine

authors：

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Acute lung injury with subsequent pneumonia and sepsis represents a major cause of morbidity and mortality in thermally injured patients. Production of nitric oxide by the neuronal and inducible nitric oxide synthase may be critically involved in the pathophysiology of the disease process at different time po...

journal_title：Critical care medicine

authors： Lange M,Connelly R,Traber DL,Hamahata A,Cox RA,Nakano Y,Bansal K,Esechie A,von Borzyskowski S,Jonkam C,Traber LD,Hawkins HK,Herndon DN,Enkhbaatar P

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Mechanical ventilation can cause ventilator-induced brain injury via afferent vagal signaling and hippocampal neurotransmitter imbalances. The triggering mechanisms for vagal signaling during mechanical ventilation are unknown. The objective of this study was to assess whether pulmonary transient receptor po...

journal_title：Critical care medicine

authors： González-López A,López-Alonso I,Pickerodt PA,von Haefen C,Amado-Rodríguez L,Reimann H,Niendorf T,Kuebler W,Albaiceta GM,Francis RCE,Spies CD

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To examine the effects of hypertonic (7.5%) saline-6% dextran 70 (HSD) and isotonic (0.9%) saline-6% dextran 70 (ISD) on cardiovascular function and intestinal perfusion in experimental endotoxin shock. DESIGN:Experimental, randomized, unblinded, interventional study. SETTING:University experimental animal ...

journal_title：Critical care medicine

authors： Oi Y,Aneman A,Svensson M,Ewert S,Dahlqvist M,Haljamäe H

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVES:To define the features of human amniotic mesenchymal stromal cell secretome and its protective properties in experimental models of acute brain injury. DESIGN:Prospective experimental study. SETTING:Laboratory research. SUBJECTS:C57Bl/6 mice. INTERVENTIONS:Mice subjected to sham or traumatic brain injury...

journal_title：Critical care medicine

authors： Pischiutta F,Brunelli L,Romele P,Silini A,Sammali E,Paracchini L,Marchini S,Talamini L,Bigini P,Boncoraglio GB,Pastorelli R,De Simoni MG,Parolini O,Zanier ER

更新日期：2016-11-01 00:00:00

abstract：:Quality improvement (QI) activities have been done as long as medicine has been practiced and are integral to safety and efficacy of patient care. The 20th century witnessed sophisticated advances of QI methods, with concurrent advances in research ethics. The suggestion that some interventional QI activities resemble...

journal_title：Critical care medicine

authors： Kofke WA,Rie MA

更新日期：2003-03-01 00:00:00

abstract：:Clinical impressions about the problem of defibrillation during states of acid-base imbalance and hypoxia have been influenced by studies involving the effect of these derangements on the ventricular fibrillation threshold. Based on body weight, energy requirements for defibrillation in normal dogs were compared to re...

journal_title：Critical care medicine

authors： Yakaitis RW,Thomas JD,Mahaffey JE

更新日期：1975-07-01 00:00:00

abstract：OBJECTIVE:In rodent models, enhanced formation of nitric oxide and formation of peroxynitrite have been implicated in the pathogenesis of various forms of shock. Here we examined the effect of mercaptoethylguanidine (MEG), an inducible nitric oxide synthase inhibitor and peroxynitrite scavenger, in a severe hemorrhagic...

journal_title：Critical care medicine

authors： Szabó A,Hake P,Salzman AL,Szabó C

更新日期：1999-07-01 00:00:00

abstract：:The hemodynamic effects of digitalis were examined in ten patients with acute cardiac failure. Administration of 10 micrograms/kg of digoxin iv resulted in significant increases in cardiac index, stroke volume index, and left ventricular stroke work index within one hour in five patients with acute myocardial infarcti...

journal_title：Critical care medicine

authors： Rackow EC,Packman MI,Weil MH

更新日期：1987-11-01 00:00:00

abstract：:Computers are commonly used to serve many functions in today's modern intensive care unit. One of the most intriguing and perhaps most challenging applications of computers has been to attempt to improve medical education. With the introduction of the first computer, medical educators began looking for ways to incorpo...

journal_title：Critical care medicine

authors： Tegtmeyer K,Ibsen L,Goldstein B

更新日期：2001-08-01 00:00:00

abstract：:The need for closed-loop control of blood pressure in acute hypertension after cardiac surgery was evaluated by estimating the amount of nurse-time required to adjust the infusion rate of sodium nitroprusside. The evaluation consisted of a nationwide telephone survey of head nurses in postsurgical ICUs at 9 institutio...

journal_title：Critical care medicine

authors： Mitchell RR

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Neurologic dysfunction, coma, and seizures are common in obstetric patients in the intensive care unit. OBJECTIVE:To review common neurologic disorders resulting in critical illness in pregnancy. REVIEW:Obstetric disorders causing coma and seizures include eclampsia, acute fatty liver of pregnancy, and amn...

journal_title：Critical care medicine

authors： Karnad DR,Guntupalli KK

更新日期：2005-10-01 00:00:00

abstract：:A portable video image-processor unit used to evaluate bedside digital subtraction angiography yields sufficient information on the major arterial vessels and the heart, using standard x-ray equipment at fluoroscopic energy levels. This unit should contribute to the evaluation of the critically ill patient in the ICU....

journal_title：Critical care medicine

authors： Janssen JH,Ackermans J,Tijdens F,Verstraelen B,de Zwaan C,Bär F,Brugada P

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:To determine the impact of adding a month of critical care training in the postgraduate year (PGY)-2 on the critical care skills of PGY-3 residents. DESIGN:Prospective, nonrandomized. SETTING:The internal medicine (IM) residency program of a tertiary care medical center. STUDY SUBJECTS:The study subjects i...

journal_title：Critical care medicine

authors： Mullon JJ,Gajic O,Gali B,Ficalora RD,Kolars JC,Afessa B

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND METHODS:A study was performed to examine the effects of the calcium-channel blocker levemopamil on neurologic outcome and neuropathology in a clinically relevant model of complete global cerebral ischemia (ventricular fibrillation in cats). Levemopamil was administered to cats starting 5 mins after resus...

journal_title：Critical care medicine

authors： Fleischer JE,Nakakimura K,Drummond JC,Scheller MS,Zornow MH,Grafe MR,Shapiro HM

更新日期：1992-01-01 00:00:00