Protection of Brain Injury by Amniotic Mesenchymal Stromal Cell-Secreted Metabolites.

abstract：OBJECTIVE:The renal effects of dopamine in critically ill patients remain controversial. Low-dose dobutamine has been reported to improve renal function. We compared the effects of various doses of dopamine and dobutamine on renal function in critically ill patients. DESIGN:Prospective, single-blind, randomized study....

journal_title：Critical care medicine

authors： Ichai C,Soubielle J,Carles M,Giunti C,Grimaud D

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:To determine: a) any heart site or tissue-specific differences in the response to increased perfusion potassium concentrations, and b) the cellular site (intracellular vs. extracellular) of the effect of calcium on reversing electrocardiographic effects of hyperkalemia. DESIGN:In vitro prospective, repeated...

journal_title：Critical care medicine

authors： Bisogno JL,Langley A,Von Dreele MM

更新日期：1994-04-01 00:00:00

abstract：:Right ventricular size and contractility were evaluated using two-dimensional echocardiography during the first days of respiratory support in 23 patients requiring mechanical ventilation for acute respiratory failure. Nine patients had normal echocardiographic right ventricular function, and nine other patients had a...

journal_title：Critical care medicine

authors： Jardin F,Gueret P,Dubourg O,Farcot JC,Margairaz A,Bourdarias JP

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVE:To investigate the interrelationship between cardiac surgery, age, circulating concentrations of the vitamin D hormone 1,25-dihydroxyvitamin D, and clinical outcome. DESIGN:Prospective, monocentric, two-arm parallel study. SETTING:Tertiary Heart and Diabetes Center in the Federal State of North Rhine-Westph...

journal_title：Critical care medicine

authors： Börgermann J,Lazouski K,Kuhn J,Dreier J,Schmidt M,Gilis-Januszewski T,Knabbe C,Gummert JF,Zittermann A

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:Although discussing a prognosis is a duty of physicians caring for critically ill patients, little is known about surrogate decision-makers' beliefs about physicians' ability to prognosticate. We sought to determine: 1) surrogates' beliefs about whether physicians can accurately prognosticate for critically ...

journal_title：Critical care medicine

authors： Zier LS,Burack JH,Micco G,Chipman AK,Frank JA,Luce JM,White DB

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:End-of-life practices vary worldwide. The objective was to demonstrate that there is no clear-cut distinction between treatments administered to relieve pain and suffering and those intended to shorten the dying process. DESIGN:Secondary analysis of a prospective, observational study. SETTING:Thirty-seven i...

journal_title：Critical care medicine

authors： Sprung CL,Ledoux D,Bulow HH,Lippert A,Wennberg E,Baras M,Ricou B,Sjokvist P,Wallis C,Maia P,Thijs LG,Solsona Duran J,ETHICUS Study Group.

更新日期：2008-01-01 00:00:00

abstract：:End tidal CO2 tension (PetCO2) and transcutaneous CO2 tension (PtcCO2) were compared with arterial CO2 (PaCO2) before and after withdrawal of mechanical ventilation in 20 patients predisposed to hypercarbia. With stable PaCO2 during mechanical ventilation, the correlation coefficient (r) between PaCO2 and PetCO2 was ....

journal_title：Critical care medicine

authors： Healey CJ,Fedullo AJ,Swinburne AJ,Wahl GW

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:This article analyzes, from a legal perspective, a recent phenomenon involving a clash between the values of attending medical personnel and the instructions of surrogate decision-makers acting on behalf of incompetent patients. Some hospitals have gone to court to challenge decisions by surrogates to continu...

journal_title：Critical care medicine

authors： Cantor NL

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVES:Measurement of blood lactate concentration in the early management of sepsis is an important step in severity assessment. High blood lactate levels in the early phase of sepsis have classically been thought to be related to tissue hypoxia, but other factors could intervene. We hypothesized that the activatio...

journal_title：Critical care medicine

authors： Contenti J,Occelli C,Corraze H,Lemoël F,Levraut J

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVES:Lung-protective ventilation for acute respiratory distress syndrome aims for providing sufficient oxygenation and carbon dioxide clearance, while limiting the harmful effects of mechanical ventilation. "Flow-controlled ventilation", providing a constant expiratory flow, has been suggested as a new lung-prote...

journal_title：Critical care medicine

authors： Schmidt J,Wenzel C,Spassov S,Borgmann S,Lin Z,Wollborn J,Weber J,Haberstroh J,Meckel S,Eiden S,Wirth S,Schumann S

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:Expert task forces have proposed that adult critical care medicine services should be regionalized in order to improve outcomes. However, it is currently unknown if high intensive care unit (ICU) patient volumes are associated with reduced mortality rate. The objective was to investigate whether high-volume I...

journal_title：Critical care medicine

authors： Glance LG,Li Y,Osler TM,Dick A,Mukamel DB

更新日期：2006-07-01 00:00:00

abstract：:Prolonged therapeutic paralysis with pancuronium is commonly used in ICUs to facilitate mechanical ventilation of patients with respiratory failure. Sedation is usually given concomitantly to reduce patient discomfort, but assessment of its adequacy is made difficult by the paralysis. We recently cared for a former IC...

journal_title：Critical care medicine

authors： Parker MM,Schubert W,Shelhamer JH,Parrillo JE

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To examine variations in case-mix, structure, resource use, and outcome performance among teaching and nonteaching intensive care units (ICU). DESIGN:Prospective inception cohort study. PATIENTS:A consecutive sample of 15,297 patients at 35 hospitals, which compared 8,269 patients admitted to 20 teaching IC...

journal_title：Critical care medicine

authors： Zimmerman JE,Shortell SM,Knaus WA,Rousseau DM,Wagner DP,Gillies RR,Draper EA,Devers K

更新日期：1993-10-01 00:00:00

abstract：:Flow rates and pressure recording accuracy were compared for Argyle 14-, 16-, and 18-ga double-lumen and Edwards 7-Fr triple-lumen CVP catheters. Physiologic saline solution was pressure-infused into dogs through one lumen and CVP was measured via the other lumen. CVP accuracy was unaltered by simultaneous rapid infus...

journal_title：Critical care medicine

authors： Ikeda S,Schweiss JF

更新日期：1985-07-01 00:00:00

abstract：:Varying concentrations of lipopolysaccharide (LPS) and mannan suspensions were mixed with either saline or plasma from normal volunteers, heated to 100 degrees C for 10 min, and then subjected to the limulus amebocyte lysate test (LAL). A positive LAL in saline required minimum LPS and mannan concentrations of 10(-11)...

journal_title：Critical care medicine

authors： Hosotsubo KK,Takezawa J,Nishijima MK,Takahashi H,Shimada Y,Yoshiya I

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:To examine the accuracy of brain multimodal monitoring-consisting of intracranial pressure, brain tissue PO2, and cerebral microdialysis--in detecting cerebral hypoperfusion in patients with severe traumatic brain injury. DESIGN:Prospective single-center study. PATIENTS:Patients with severe traumatic brain ...

journal_title：Critical care medicine

authors： Bouzat P,Marques-Vidal P,Zerlauth JB,Sala N,Suys T,Schoettker P,Bloch J,Daniel RT,Levivier M,Meuli R,Oddo M

更新日期：2015-02-01 00:00:00

abstract：:The Pediatric Risk of Mortality (PRISM) score was developed from the Physiologic Stability Index (PSI) to reduce the number of physiologic variables required for pediatric ICU (PICU) mortality risk assessment and to obtain an objective weighting of the remaining variables. Univariate and multivariate statistical techn...

journal_title：Critical care medicine

authors： Pollack MM,Ruttimann UE,Getson PR

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVES:To perform a scoping literature review of cognitive, psychiatric, and quality of life outcomes in adults undergoing extracorporeal membrane oxygenation for any indication. DATA SOURCES:We searched PubMed, EMBASE, Cochrane Library, Web of Science, CINAHL, and PsycINFO from inception to June 2019. STUDY SELE...

journal_title：Critical care medicine

authors： Khan IR,Saulle M,Oldham MA,Weber MT,Schifitto G,Lee HB

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:Fever is common and associated with increased mortality among patients admitted to adult ICUs, yet recent literature suggests that the incidence of fever may be decreasing. The objective of this study was to determine whether the incidence of fever in adult ICUs changed over time and the factors responsible ...

journal_title：Critical care medicine

authors： Niven DJ,Stelfox HT,Shahpori R,Laupland KB

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:To determine the frequency of advance directives or directives disclosed by healthcare agents and their influence on decisions to withdraw/withhold life-sustaining care in neurocritically ill adults. DATA SOURCES:PubMed, Embase, and Cochrane databases. STUDY SELECTION:Screening was performed using predefin...

journal_title：Critical care medicine

authors： Sutter R,Meyer-Zehnder B,Baumann SM,Marsch S,Pargger H

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:In 2003, critical care and infectious disease experts representing 11 international organizations developed management guidelines for the use of corticosteroid therapy in patients with sepsis and septic shock that would be of practical use for the bedside clinician, under the auspices of the Surviving Sepsis ...

journal_title：Critical care medicine

authors： Keh D,Sprung CL

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the pathophysiology involved in hypocalcemia in septic shock and to investigate the value of calcium administration. DESIGN:Prospective, randomized placebo-controlled trial with parallel groups. SETTING:Animal research laboratory at the University Hospital of Uppsala. SUBJECTS:Twenty-four pigs ...

journal_title：Critical care medicine

authors： Carlstedt F,Eriksson M,Kiiski R,Larsson A,Lind L

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:Pathogens that cause pneumonia may be treated in a targeted fashion by antibiotics, but if this therapy fails, then treatment involves only nonspecific supportive measures, independent of the inciting infection. The purpose of this study was to determine whether host response is similar after disparate infect...

journal_title：Critical care medicine

authors： McConnell KW,McDunn JE,Clark AT,Dunne WM,Dixon DJ,Turnbull IR,Dipasco PJ,Osberghaus WF,Sherman B,Martin JR,Walter MJ,Cobb JP,Buchman TG,Hotchkiss RS,Coopersmith CM

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Families and other surrogate decisionmakers for chronically critically ill patients often lack information about patient prognosis or options for care. This study describes an approach to develop and validate a printed information brochure about chronic critical illness aimed at improving comprehension of the...

journal_title：Critical care medicine

authors： Carson SS,Vu M,Danis M,Camhi SL,Scheunemann LP,Cox CE,Hanson LC,Nelson JE

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To assess the effects of step-changes in tidal volume on work of breathing during lung-protective ventilation in patients with acute lung injury (ALI) or the acute respiratory distress syndrome (ARDS). DESIGN:Prospective, nonconsecutive patients with ALI/ARDS. SETTING:Adult surgical, trauma, and medical int...

journal_title：Critical care medicine

authors： Kallet RH,Campbell AR,Dicker RA,Katz JA,Mackersie RC

更新日期：2006-01-01 00:00:00

abstract：:Percutaneous cholecystostomy was employed successfully as an alternative to cholecystectomy for the treatment of acute cholecystitis with perforation in an elderly woman. The procedure, performed portably in the cardiac care unit, was selected because progressive cardiac and renal decompensation made the patient an ex...

journal_title：Critical care medicine

authors： Longmaid HE 3rd,Bassett JG,Gottlieb H

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVE:Resuscitation of hemorrhagic hypotension after traumatic brain injury is challenging. A hemoglobin-based oxygen carrier may offer advantages. The novel therapeutic hemoglobin-based oxygen carrier, polynitroxylated pegylated hemoglobin (PNPH), may represent a neuroprotective hemoglobin-based oxygen carrier for...

journal_title：Critical care medicine

authors： Shellington DK,Du L,Wu X,Exo J,Vagni V,Ma L,Janesko-Feldman K,Clark RS,Bayir H,Dixon CE,Jenkins LW,Hsia CJ,Kochanek PM

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Toxic free radicals cause dysfunction of respiratory muscles, probably leading to respiratory distress. Exposure to high concentrations of oxygen generates plenty of free radicals. Lidocaine scavenges the reactive molecules. The purposes of the current study were first to examine whether hyperoxia impairs dia...

journal_title：Critical care medicine

authors： Nishina K,Mikawa K,Shiga M,Kodama S,Kagawa T,Maekawa N,Obara H

更新日期：2000-06-01 00:00:00

abstract：:In the pathogenesis of sepsis, inflammation and coagulation play a pivotal role. Increasing evidence points to an extensive cross-talk between these two systems, whereby inflammation leads to activation of coagulation, and coagulation also considerably affects inflammatory activity. Molecular pathways that contribute ...

journal_title：Critical care medicine

authors： Levi M,van der Poll T

更新日期：2010-02-01 00:00:00

abstract：:The focus on improving education in critical care medicine must begin early in medical school training and further be promoted during residency if there is to be an increase in intensivists in the hospital workforce. This is "critical" to healthcare reform movements that are endorsing full-time critical care coverage ...

journal_title：Critical care medicine

authors： Croley WC,Rothenberg DM

更新日期：2007-02-01 00:00:00