Research ethics and law of healthcare system quality improvement: the conflict of cost containment and quality.

abstract：OBJECTIVE:To describe a case of intentional ingestion of hand sanitizer in our hospital and to review published cases and those reported to the American Association of Poison Control Centers' National Poison Data System. DESIGN:A case report, a literature review of published cases, and a query of the National Poison D...

journal_title：Critical care medicine

authors： Gormley NJ,Bronstein AC,Rasimas JJ,Pao M,Wratney AT,Sun J,Austin HA,Suffredini AF

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:The adrenal gland is the endocrine organ most commonly involved in patients infected with human immunodeficiency virus (HIV). It is important to recognize patients with adrenal insufficiency, because this disorder may be fatal if untreated. The incidence of adrenal insufficiency in critically ill HIV-infected...

journal_title：Critical care medicine

authors： Marik PE,Kiminyo K,Zaloga GP

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:Develop a scoring system that can assess the management of septic shock by individuals and teams. DESIGN:Retrospective review of videotapes of critical care house staff managing a standardized simulation of septic shock. SETTING:Academic medical center; videotapes were made in a recreated intensive care uni...

journal_title：Critical care medicine

authors： Ottestad E,Boulet JR,Lighthall GK

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To review current knowledge about the impact of prolonged mechanical ventilation on diaphragmatic function and biology. MEASUREMENTS:Systematic literature review. CONCLUSIONS:Prolonged mechanical ventilation can promote diaphragmatic atrophy and contractile dysfunction. As few as 18 hrs of mechanical ventil...

journal_title：Critical care medicine

authors： Powers SK,Kavazis AN,Levine S

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:We sought to review findings from recent literature on the postresuscitation care of cardiac arrest patients using therapeutic hypothermia as part of nontrial treatment. DESIGN:Literature review. SETTING:Hospital-based environment. SUBJECTS:Patients initially resuscitated from cardiac arrest who underwent...

journal_title：Critical care medicine

authors： Sagalyn E,Band RA,Gaieski DF,Abella BS

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To assess the mortality rate and complications in a population of surgical patients with severe adult respiratory distress syndrome (ARDS) treated with positive end-expiratory pressure (PEEP) of > 15 cm H2O in an attempt to reduce intrapulmonary shunt to approximately 0.20 and reduce FIO2 to < 0.50. DESIGN:R...

journal_title：Critical care medicine

authors： DiRusso SM,Nelson LD,Safcsak K,Miller RS

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND METHODS:We postulated that low-dose heparin (10 IU/kg.hr) administered as a continuous iv infusion may prevent or ameliorate the induction of thrombin-induced disseminated intravascular coagulation in baboons under general anesthesia. In a nonrandomized experiment lasting 8 hrs, animals were divided into...

journal_title：Critical care medicine

authors： du Toit HJ,Coetzee AR,Chalton DO

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between treatment-related variables for Candida bloodstream infection and hospital mortality. DESIGN:Retrospective cohort analysis. SETTING:Thousand two hundred-bed academic medical center. PATIENTS:A total of 245 consecutive patients with Candida bloodstream infections who rece...

journal_title：Critical care medicine

authors： Labelle AJ,Micek ST,Roubinian N,Kollef MH

更新日期：2008-11-01 00:00:00

abstract：:The effect of halothane on electrodes covered with polypropylene and FEP teflon membranes, used for monitoring transcutaneous oxygen tension, was compared in vitro and in patients anesthetized with halothane. In vitro experiments with halothane showed a false increase in PO2 measured by the electrode covered with poly...

journal_title：Critical care medicine

authors： Samra SK

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVE:To assess survival after cardiac arrest and to determine whether age is an independent determinant of late mortality or poor neurologic outcome. DESIGN:Analyses using results of Brain Resuscitation Clinical Trial I (1979 to 1984) and Brain Resuscitation Clinical Trial II (1984 to 1989), two randomized, doubl...

journal_title：Critical care medicine

authors： Rogove HJ,Safar P,Sutton-Tyrrell K,Abramson NS

更新日期：1995-01-01 00:00:00

abstract：:Impedance respiratory monitoring is the standard technique for detecting apnea in infants. A miniature microphone/amplifier system has been used to sense breath sounds over the trachea in order to detect both central and obstructive apnea episodes in infants and children. The tracheal microphone has several advantages...

journal_title：Critical care medicine

authors： Beckerman RC,Wegmann MJ,Waring WW

更新日期：1982-06-01 00:00:00

abstract：OBJECTIVES:Muscle weakness associated with critical illness can be due to the illness itself, immobilization associated with it, and/or to concomitant use of drugs that affect neuromuscular transmission. This study investigated the contribution of immobilization per se to the muscle dysfunction, as well as the associat...

journal_title：Critical care medicine

authors： Ibebunjo C,Martyn JA

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVES:To track compliance by an interprofessional team with the Awakening and Breathing Coordination, Choice of drugs, Delirium monitoring and management, Early mobility, and Family engagement (ABCDEF) bundle in implementing the Pain, Agitation, and Delirium guidelines. The aim was to study the association between...

journal_title：Critical care medicine

authors： Barnes-Daly MA,Phillips G,Ely EW

更新日期：2017-02-01 00:00:00

abstract：CONTEXT:The results of studies on noninvasive positive pressure ventilation (NPPV) for acute hypoxemic respiratory failure unrelated to cardiogenic pulmonary edema have been inconsistent. OBJECTIVE:To assess the effect of NPPV on the rate of endotracheal intubation, intensive care unit and hospital length of stay, and...

journal_title：Critical care medicine

authors： Keenan SP,Sinuff T,Cook DJ,Hill NS

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To examine the pulmonary and cardiac function of children who survived an episode of acute hypoxemic respiratory failure. DESIGN:Descriptive cohort analysis. SETTING:Pediatric clinical research center of a university hospital. PATIENTS:Utilizing the criteria of PaO2 < 75 torr (< 10 kPa) with an FIO2 of > 0...

journal_title：Critical care medicine

authors： Weiss I,Ushay HM,DeBruin W,O'Loughlin J,Rosner I,Notterman D

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:To assess the value of soluble triggering receptor expressed on myeloid cells-1 as a biomarker of infection in patients with neutropenic fever comparing with procalcitonin and C-reactive protein. DESIGN:Prospective, comparative, single-center study. SETTING:Hematology ward at a university hospital. SUBJECT...

journal_title：Critical care medicine

authors： Lin CH,Yao M,Hsu SC,Ho CC,Lin MT,Lin CA,Hu FC,Yu CJ,Tien HF

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To determine if intracranial pressure monitor placement in patients with acute liver failure is associated with significant clinical outcomes. DESIGN:Retrospective multicenter cohort study. SETTING:Academic liver transplant centers comprising the U.S. Acute Liver Failure Study Group. PATIENTS:Adult critica...

journal_title：Critical care medicine

authors： Karvellas CJ,Fix OK,Battenhouse H,Durkalski V,Sanders C,Lee WM,U S Acute Liver Failure Study Group.

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the relationship of patient care variables to survival and functional outcome in the pediatric population with traumatic brain injury. DESIGN:Retrospective chart review. SETTING:A 16-bed pediatric critical care unit in an academic community children's hospital. PATIENT...

journal_title：Critical care medicine

authors： Hackbarth RM,Rzeszutko KM,Sturm G,Donders J,Kuldanek AS,Sanfilippo DJ

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the impact of an emergency department mechanical ventilation protocol on clinical outcomes and adherence to lung-protective ventilation in patients with acute respiratory distress syndrome. DESIGN:Quasi-experimental, before-after trial. SETTING:Emergency department and ICUs of an academic cente...

journal_title：Critical care medicine

authors： Fuller BM,Ferguson IT,Mohr NM,Drewry AM,Palmer C,Wessman BT,Ablordeppey E,Keeperman J,Stephens RJ,Briscoe CC,Kolomiets AA,Hotchkiss RS,Kollef MH

更新日期：2017-04-01 00:00:00

abstract：:The present trend in managed care has meant downsizing expectations concerning the availability of support for resuscitation research. This trend applies to funding possibilities from industry, governmental agencies, and nongovernmental agencies (Table 1). There will be increasing barriers to making innovations. Truth...

journal_title：Critical care medicine

authors： Thompson WL,Bellamy R,Cummins RO,Delooz HH,Dick W,Kochanek PM,Ornato JP,Ricci EM,Weil MH,Winter PM

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:The Sequential Organ Failure Assessment (SOFA) score was developed to quantify the severity of patients' illness, based on the degree of organ dysfunction. This study aimed to evaluate the accuracy and the reliability of SOFA scoring. DESIGN:Prospective study. SETTING:Adult intensive care unit (ICU) in a te...

journal_title：Critical care medicine

authors： Arts DG,de Keizer NF,Vroom MB,de Jonge E

更新日期：2005-09-01 00:00:00

abstract：:The tradition of clinical ultrasound in the hands of physicians who provide critical care to the most acutely ill patients stretches back into the 1980s and is rich with experiences from surgical, emergency medicine, and other practices. Now, as critical care ultrasound explodes around the world, it is important to re...

journal_title：Critical care medicine

authors： Kendall JL,Hoffenberg SR,Smith RS

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To improve control of blood glucose concentrations in critically ill patients through use of a bedside, nurse-managed, intravenous insulin nomogram. DESIGN:Retrospective, before-after cohort study. SETTING:Fifteen-bed mixed medical/surgical intensive care unit in a tertiary, teaching hospital. PATIENTS:A t...

journal_title：Critical care medicine

authors： Brown G,Dodek P

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVES:To evaluate the internal consistency, validity, responsiveness, and minimal important difference of the Functional Status Score for the ICU, a physical function measure designed for the ICU. DESIGN:Clinimetric analysis. SETTINGS:Five international datasets from the United States, Australia, and Brazil. PA...

journal_title：Critical care medicine

authors： Huang M,Chan KS,Zanni JM,Parry SM,Neto SG,Neto JA,da Silva VZ,Kho ME,Needham DM

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:Patients requiring admission to an ICU may subsequently experience cognitive decline. Our objective was to investigate longitudinal cognitive trajectories in older adults hospitalized in ICUs. We hypothesized that individuals hospitalized for critical illness develop greater cognitive decline compared with t...

journal_title：Critical care medicine

authors： Schulte PJ,Warner DO,Martin DP,Deljou A,Mielke MM,Knopman DS,Petersen RC,Weingarten TN,Warner MA,Rabinstein AA,Hanson AC,Schroeder DR,Sprung J

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:Levosimendan is a novel inodilator that improves cardiac contractility by sensitizing troponin C to calcium. This drug has proved to be effective in treating advanced congestive heart failure but has not been evaluated in septic settings. The purpose of the present study was to study the effects of this drug ...

journal_title：Critical care medicine

authors： Oldner A,Konrad D,Weitzberg E,Rudehill A,Rossi P,Wanecek M

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:The Acute Respiratory Distress Syndrome Network protocol recommends limiting tidal volume and plateau pressure; it also recommends increasing respiratory rate to prevent hypercapnia. We tested a strategy that combines the low tidal volume with lower respiratory rates and minimally invasive CO2 removal. SUBJE...

journal_title：Critical care medicine

authors： Grasso S,Stripoli T,Mazzone P,Pezzuto M,Lacitignola L,Centonze P,Guarracino A,Esposito C,Herrmann P,Quintel M,Trerotoli P,Bruno F,Crovace A,Staffieri F

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the impact of a comprehensive unit-based safety program on safety climate in a large cohort of intensive care units participating in the Keystone intensive care unit project. DESIGN/SETTING:A prospective cohort collaborative study to improve quality of care and safety culture by implementing and...

journal_title：Critical care medicine

authors： Sexton JB,Berenholtz SM,Goeschel CA,Watson SR,Holzmueller CG,Thompson DA,Hyzy RC,Marsteller JA,Schumacher K,Pronovost PJ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:One form of sepsis, or endotoxic shock, is a hyperactivated systemic response caused by excessive expression of proinflammatory mediators, which results from Gram-negative bacterial lipopolysaccharide-stimulated Toll-like receptor-4 signaling. This lipopolysaccharide signaling is known to consist of a MyD88-...

journal_title：Critical care medicine

authors： Benavides U,Gonzalez-Murguiondo M,Harii N,Lewis CJ,Schwartz AL,Giuliani C,Napolitano G,Dagia NM,Malgor R,McCall KD,Kohn LD

更新日期：2012-03-01 00:00:00

abstract：:Reimbursement policies are a critical step in the incorporation of new technologies and therapies into the clinical armamentarium. Reimbursement is an umbrella concept describing the process to manage and pay for healthcare services, including benefit coverage, coding, and payment processes. The technologies and servi...

journal_title：Critical care medicine

authors： Reaven NL,Rosenbloom J

更新日期：2009-07-01 00:00:00