The effect of daily bathing with chlorhexidine on the acquisition of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and healthcare-associated bloodstream infections: results of a quasi-experimental multicenter trial.

abstract：OBJECTIVE:To assess the statistical association of the Acute Physiology and Chronic Health Evaluation (APACHE II) score with multiple intervention and outcome variables in surgical ICU patients. DESIGN:Continuous data collection on every patient admitted to the surgical ICU for a 21-month period. MATERIALS AND METHOD...

journal_title：Critical care medicine

authors： Rutledge R,Fakhry SM,Rutherford EJ,Muakkassa F,Baker CC,Koruda M,Meyer AA

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:To compare the cardiopulmonary and peripheral circulatory effects of the nonselective nitric oxide synthase (NOS) inhibitor NG-nitro-L-arginine methyl ester (L-NAME) to the more selective inducible NOS inhibitor S-methylisothiourea (SMT) and to phenylephrine (PE) in endotoxic and normal swine. DESIGN:Prospec...

journal_title：Critical care medicine

authors： Cohen RI,Shapir Y,Davis A,Loona R,Scharf SM

更新日期：2000-09-01 00:00:00

abstract：:Critical Care Medicine encompasses an extremely broad scope. Examination questions were, therefore, chosen to cover a wide variety of critical care topics. A near Gaussian distribution of scores was found for all physician groups studied. We believe the low mean score of 15% reflects the general difficulty of the exam...

journal_title：Critical care medicine

authors： Veremakis C,Taylor RW

更新日期：1983-05-01 00:00:00

abstract：:Thromboembolic disease ranks among the most dangerous and common complication in the postoperative or post-traumatic patient. As previously mentioned, the incidence is increasing and fatalities from this complication have also risen substantially. The pathogenesis of thromboembolic disease and the predictability of it...

journal_title：Critical care medicine

authors： Evarts CM

更新日期：1976-03-01 00:00:00

abstract：OBJECTIVES:Increasing age is a well-recognized risk factor for in-hospital mortality in patients receiving extracorporeal membrane oxygenation for cardiogenic shock, but the shape of this relationship is unknown. In addition, the impact of age on hospital length of stay, patterns of patient disposition, and costs has b...

journal_title：Critical care medicine

authors： Chung M,Zhao Y,Strom JB,Shen C,Yeh RW

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:Survivors of critical illness in early life are at risk of long-term-memory and attention impairments. However, their neurobiologic substrates remain largely unknown. DESIGN:A prospective follow-up study. SETTING:Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands. PATIENTS:Thirty-eight scho...

journal_title：Critical care medicine

authors： Schiller RM,IJsselstijn H,Madderom MJ,Rietman AB,Smits M,van Heijst AFJ,Tibboel D,White T,Muetzel RL

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:When a patient is incompetent, the family is often considered to be a natural surrogate. The doctors' responsiveness to family wishes may vary. We explored if doctors' personal characteristics were associated with responsiveness to the relatives' wishes when admission to the intensive care unit (ICU) is consi...

journal_title：Critical care medicine

authors： Escher M,Perneger TV,Heidegger CP,Chevrolet JC

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Intensive care units (ICUs) are recognized as stressful environments. However, the conditions in which stressors may affect health professionals' performance and well-being and the conditions that potentially lead to impaired performance and staff psychological distress are not well understood. OBJECTIVES:T...

journal_title：Critical care medicine

authors： Piquette D,Reeves S,LeBlanc VR

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:There is growing recognition that high-quality care for patients and families in the ICU requires exemplary interprofessional collaboration and communication. One important aspect is how the ICU team makes complex decisions. However, no recommendations have been published on interprofessional shared decision...

journal_title：Critical care medicine

authors： Michalsen A,Long AC,DeKeyser Ganz F,White DB,Jensen HI,Metaxa V,Hartog CS,Latour JM,Truog RD,Kesecioglu J,Mahn AR,Curtis JR

更新日期：2019-09-01 00:00:00

abstract：:This report documents the validity of clinical measurements of oxygen consumption (VO2) and carbon dioxide production (VCO2) made with a new metabolic gas monitor (MGM) suitable for use in critically ill patients receiving mechanical ventilatory support. Paired samples of inspired and expired gases were obtained, and ...

journal_title：Critical care medicine

authors： Nelson LD,Anderson HB,Garcia H

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:Overdoses of calcium channel blocker agents result in hyperglycemia, primarily due to the blockade of pancreatic L-type calcium channels and insulin resistance on the cellular level. The clinical significance of the hyperglycemia in this setting has not previously been described. METHODS:This study is a ret...

journal_title：Critical care medicine

authors： Levine M,Boyer EW,Pozner CN,Geib AJ,Thomsen T,Mick N,Thomas SH

更新日期：2007-09-01 00:00:00

abstract：:In 179 healthy boys and girls, the relationship between body surface area (S) in dm2 and body weight (bw) in kg was investigated. The body surface was calculated from the DuBois and DuBois formula. For infants below 20 kg, the relationship followed the regression equation S=3.6kg + 9; r=0.996. For infants with bw betw...

journal_title：Critical care medicine

authors： Lindahl S,Okmian L

更新日期：1981-11-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to determine whether selective inflammatory cytokine concentrations within cerebrospinal fluid are useful markers for the differential diagnosis of aseptic and bacterial meningitis within neurosurgical patients. DESIGN:Prospective, open-label, observational, cohort stud...

journal_title：Critical care medicine

authors： Liu ZH,Tu PH,Chen NY,Yip PK,Bowes AL,Lee CC,Chan SH,Kung CC,Wang AY,Wu CT,Lee ST

更新日期：2015-11-01 00:00:00

abstract：:Instantaneous heart rate, indices of long-term and short-term heart-rate variability (HRV), and transcutaneous O2 (PtcO2) and CO2 (PtcCO2) tensions were recorded simultaneously on 164 occasions in 16 neonates. There was significant inverse correlation between PtcCO2 and both HRV indices, while no linear correlation wa...

journal_title：Critical care medicine

authors： Aärimaa T,Kero P,Välimäki I

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:Neutropenia recovery may be associated with an increased risk of respiratory function deterioration. A history of pneumonia complicating neutropenia has been identified as the leading cause of adult respiratory distress syndrome during neutropenia recovery in patients receiving anticancer chemotherapy, sugges...

journal_title：Critical care medicine

authors： Azoulay E,Attalah H,Yang K,Herigault S,Jouault H,Brun-Buisson C,Brochard L,Harf A,Schlemmer B,Delclaux C

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To evaluate whether current criteria for the diagnosis of brain death fulfill the requirement for the "irreversible cessation of all functions of the entire brain, including the brainstem." DATA SOURCES:Clinical, philosophical, legal, and public policy literature on the subject of brain death. DATA EXTRACTI...

journal_title：Critical care medicine

authors： Truog RD,Fackler JC

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVE:To determine the long-term outcome of noninvasive ventilation in chronic obstructive pulmonary disease patients who refused intubation for acute hypercapnic respiratory failure. DESIGN:Prospective, observational study. SETTING:Noninvasive ventilation unit in an acute regional hospital in Hong Kong. METHODS...

journal_title：Critical care medicine

authors： Chu CM,Chan VL,Wong IW,Leung WS,Lin AW,Cheung KF

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Subcutaneously administered low-molecular-weight heparins are widely used for prevention of venous thromboembolism. The appropriateness of the subcutaneous route in critically ill patients has never been established. OBJECTIVE:To determine anti-Xa activities in critically ill patients and in noncritically i...

journal_title：Critical care medicine

authors： Priglinger U,Delle Karth G,Geppert A,Joukhadar C,Graf S,Berger R,Hülsmann M,Spitzauer S,Pabinger I,Heinz G

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:Treatment of preterm infants with respiratory distress syndrome (RDS) with exogenous surfactant has greatly improved clinical outcome. Some infants require multiple doses, and it has not been studied whether these large amounts of exogenous surfactant disturb endogenous surfactant metabolism in humans. We stu...

journal_title：Critical care medicine

authors： Bunt JE,Carnielli VP,Janssen DJ,Wattimena JL,Hop WC,Sauer PJ,Zimmermann LJ

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that therapeutic hypercapnia enhances the proinflammatory responses to endotoxemia in the lung and spleen of rats. DESIGN:Prospective randomized study. SETTINGS:Hospital research institute. SUBJECTS:Forty-eight adult male rats. INTERVENTIONS:Rats were randomly assigned for a 24-hr p...

journal_title：Critical care medicine

authors： Norozian FM,Leoncio M,Torbati D,Meyer K,Raszynski A,Totapally BR

更新日期：2011-06-01 00:00:00

abstract：:A new device has been developed to estimate continuously and noninvasively cardiac output from the thoracic electrical bioimpedance (CObi). CObi was compared to cardiac output by thermodilution (COtd) in five anesthetized dogs. Blood pressure, blood volume, and blood flow were manipulated by hemorrhage and infusions o...

journal_title：Critical care medicine

authors： Tremper KK,Hufstedler SM,Barker SJ,Zaccari J,Harris D,Anderson S,Roohk V

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:To discuss a potential role for endothelial cell apoptosis in the pathogenesis of sepsis. DATA SOURCES:Studies published in biomedical journals and studies from the authors' laboratory. STUDY SELECTION:In vitro and in vivo studies of endothelial cell apoptosis in endotoxin and sepsis models. DATA EXTRACTIO...

journal_title：Critical care medicine

authors： Hotchkiss RS,Tinsley KW,Swanson PE,Karl IE

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVES:To measure total serum nitrite and nitrate concentrations in children with the sepsis syndrome as an indicator of endogenous nitric oxide production. To determine if there is an association between total serum nitrite and nitrate concentrations and vascular responsiveness to norepinephrine. DESIGN:A prospec...

journal_title：Critical care medicine

authors： Wong HR,Carcillo JA,Burckart G,Shah N,Janosky JE

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVES:To define a curriculum that outlines the core knowledge residents should possess upon completion of graduate training in order to be able to formulate and initiate a treatment plan for the critically ill patient. DATA SOURCES:Requirements for training program certification as outlined by the Accreditation C...

journal_title：Critical care medicine

authors：

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:To determine whether the difference between oxygen consumption (VO2) measured by metabolic gas monitoring systems and by the Fick principle is related to venous admixture, deadspace/tidal volume ratio, or alveolar-arterial oxygen tension gradient in critically ill patients. DESIGN:A prospective study. SETTI...

journal_title：Critical care medicine

authors： Myburgh JA,Webb RK,Worthley LI

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Acute lung injury secondary to smoke inhalation is a major source of morbidity and mortality in burn patients. We tested the hypothesis that nebulized epinephrine would ameliorate pulmonary dysfunction secondary to acute lung injury by reducing airway hyperemia and edema formation and mediating bronchodilatat...

journal_title：Critical care medicine

authors： Lange M,Hamahata A,Traber DL,Cox RA,Kulp GA,Nakano Y,Traber LD,Herndon DN,Enkhbaatar P

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To develop definitions of infection that can be used in clinical trials in patients with sepsis. CONTEXT:Infection is a key component of the definition of sepsis, yet there is currently no agreement on the definitions that should be used to identify specific infections in patients with sepsis. Agreeing on a ...

journal_title：Critical care medicine

authors： Calandra T,Cohen J,International Sepsis Forum Definition of Infection in the ICU Consensus Conference.

更新日期：2005-07-01 00:00:00

abstract：:High-frequency jet ventilation using a jet injector located at the right mainstem bronchus was superimposed on standard mechanical ventilation to ventilate the injured lung of a patient with unilateral massive atelectasis secondary to pulmonary hemorrhage. This technique of differential ventilation markedly improved a...

journal_title：Critical care medicine

authors： Nishimura M,Takezawa J,Nishijima MK,Taenaka N,Shimada Y,Yoshiya I,Fujimoto Y

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVES:To determine whether high rates of ineffective triggering within the first 24 hrs of mechanical ventilation (MV) are associated with longer MV duration and shorter ventilator-free survival (VFS). DESIGN:Prospective cohort study. SETTING:Medical intensive care unit (ICU) at an academic medical center. PATI...

journal_title：Critical care medicine

authors： de Wit M,Miller KB,Green DA,Ostman HE,Gennings C,Epstein SK

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:The current trend to manage critically ill hematologic patients admitted with acute respiratory failure is to perform noninvasive ventilation to avoid endotracheal intubation. However, failure of noninvasive ventilation may lead to an increased mortality. DESIGN:Retrospective study to determine the frequenc...

journal_title：Critical care medicine

authors： Adda M,Coquet I,Darmon M,Thiery G,Schlemmer B,Azoulay E

更新日期：2008-10-01 00:00:00