Admission of incompetent patients to intensive care: doctors' responsiveness to family wishes.

abstract：OBJECTIVE:The mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway is an essential component of innate immunity necessary for mediating proinflammatory responses in the setting of sepsis. We previously demonstrated that the mitogen-activated protein kinase 1/2 inhibitor trametinib pr...

journal_title：Critical care medicine

authors： Smith JA,Mayeux PR,Schnellmann RG

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Critically ill patients often develop large gastric residual volumes during nasogastric feeding as a result of poor gastroduodenal motility. Nasojejunal feeding may decrease the severity of this complication. The aim of this study was to determine whether nasojejunal feeding improved tolerance of enteral nutr...

journal_title：Critical care medicine

authors： Davies AR,Froomes PR,French CJ,Bellomo R,Gutteridge GA,Nyulasi I,Walker R,Sewell RB

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:Optimistic expectations about prognosis by surrogate decision-makers in ICUs are common, but there are few data about the causes and clinical consequences. Our objective was to determine the causes of optimistic expectations about prognosis among surrogates and whether it is associated with more use of life ...

journal_title：Critical care medicine

authors： White DB,Carson S,Anderson W,Steingrub J,Bird G,Curtis JR,Matthay M,Peterson M,Buddadhumaruk P,Shields AM,Ernecoff N,Shotsberger K,Weissfeld L,Chang CH,Pike F,Lo B,Hough CL

更新日期：2019-09-01 00:00:00

abstract：:Amikacin was introduced as the primary aminoglycoside in our hospital to prevent the further development of multiply resistant Gram-negative organisms. This study compares clinical and microbiological data before and after institution of this policy to evaluate the influence on clinical outcome in patients as well as ...

journal_title：Critical care medicine

authors： Hammond JM,Potgieter PD,Forder AA,Plumb H

更新日期：1990-06-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of norepinephrine on static (right atrial pressure, pulmonary artery occlusion pressure ) and dynamic (pulse pressure variation and arterial systolic pressure variation) preload indicators in experimental hemorrhagic shock. DESIGN:Prospective controlled experimental study. SETTING:...

journal_title：Critical care medicine

authors： Nouira S,Elatrous S,Dimassi S,Besbes L,Boukef R,Mohamed B,Abroug F

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to test the hypothesis that the right ventricle is more dilated during resuscitation from cardiac arrest caused by pulmonary embolism, compared with hypoxia and primary arrhythmia. DESIGN:Twenty-four pigs were anesthetized and cardiac arrest was induced using three different method...

journal_title：Critical care medicine

authors： Aagaard R,Caap P,Hansson NC,Bøtker MT,Granfeldt A,Løfgren B

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:Supplementation with tetrahydrobiopterin, a nitric oxide synthase cofactor, may reduce microvascular endothelial dysfunction in severe sepsis. We studied whether tetrahydrobiopterin administration exerts beneficial effects in an ovine septic shock model. DESIGN:Randomized animal study. SETTING:University ho...

journal_title：Critical care medicine

authors： He X,Su F,Velissaris D,Salgado DR,de Souza Barros D,Lorent S,Taccone FS,Vincent JL,De Backer D

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE AND DESIGN:To review and discuss selected literature, expert opinion, and conventional care of the hyperglycemic perioperative or critically ill patient. MAIN POINTS:Diabetes mellitus, the most commonly encountered perioperative endocrinopathy, continues to increase dramatically in prevalence. Diabetes is th...

journal_title：Critical care medicine

authors： Coursin DB,Connery LE,Ketzler JT

更新日期：2004-04-01 00:00:00

abstract：:A case of rabies was treated with intensive medical support. This led to a prolongation of life to 25 days. The neurologic progression of the disease was monitored clinically and with serial EEG. This prolonged course enabled us to witness and manage a wide variety of unusual complications including the adult respirat...

journal_title：Critical care medicine

authors： Udwadia ZF,Udwadia FE,Katrak SM,Dastur DK,Sekhar M,Lall A,Kumta A,Sane B

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:To investigate, in restrictive patients, the influence of pressure ramp slope values on the efficacy of pressure support ventilation. DESIGN:Prospective study. SETTING:A university hospital medical intensive care unit. PATIENTS:Twelve intubated restrictive patients. INTERVENTIONS:Patients were randomly as...

journal_title：Critical care medicine

authors： Bonmarchand G,Chevron V,Ménard JF,Girault C,Moritz-Berthelot F,Pasquis P,Leroy J

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVES:Endovascular treatment for acute ischemic stroke with a large vessel occlusion was recently shown to be effective. We aimed to develop a score capable of predicting large vessel occlusion eligible for endovascular treatment in the early hospital management. DESIGN:Retrospective, cohort study. SETTING:Two t...

journal_title：Critical care medicine

authors： Vanacker P,Heldner MR,Amiguet M,Faouzi M,Cras P,Ntaios G,Arnold M,Mattle HP,Gralla J,Fischer U,Michel P

更新日期：2016-06-01 00:00:00

abstract：:The Simplified Acute Physiology Score (SAPS), the Acute Physiology and Chronic Health Evaluation II (APACHE II), the Acute Physiology Score (APS), and the Coronary Prognostic Index (CPI), calculated within the first 24 h of ICU admission, were compared in 76 patients with acute myocardial infarction (AMI). Sixteen (21...

journal_title：Critical care medicine

authors： Moreau R,Soupison T,Vauquelin P,Derrida S,Beaucour H,Sicot C

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND AND METHODS:Calcium-channel blockers may attenuate vasospasm after transient ischemia and improve organ blood flow after resuscitation. Our aim was to assess the effect of diltiazem on systemic oxygen delivery and consumption, hemodynamics, electroencephalogram (EEG), and organ blood flow after restoration o...

journal_title：Critical care medicine

authors： Lindner KH,Prengel AW,Ahnefeld FW,Ensinger H,Schürmann W

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:To compare silver-coated and uncoated central venous catheters regarding bacterial colonization. To assess the relative contribution of catheter hub and skin colonization to catheter tip colonization. DESIGN:Prospective, randomized clinical trial. SETTING:Intensive care unit in a university hospital. PATIE...

journal_title：Critical care medicine

authors： Bach A,Eberhardt H,Frick A,Schmidt H,Böttiger BW,Martin E

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To review the rationale for the regionalization of adult critical care and discuss how lessons from the trauma experience may be relevant to this debate. DESIGN:Narrative review and opinion. RESULTS:Variation in the quality of critical care among hospitals has prompted calls for regionalization of care for ...

journal_title：Critical care medicine

authors： Kahn JM,Branas CC,Schwab CW,Asch DA

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:Significant mortality in patients with sepsis results from the development of multiple organ dysfunction syndrome. Small-volume resuscitation with 7.5% NaCl hypertonic saline has been proposed to restore physiologic hemodynamics in hemorrhagic shock. Therefore, we hypothesized that hypertonic saline resuscita...

journal_title：Critical care medicine

authors： Shih CC,Chen SJ,Chen A,Wu JY,Liaw WJ,Wu CC

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:The administration of endotoxin to healthy humans reduces cerebral blood flow but its influence on dynamic cerebral autoregulation remains unknown. We considered that a reduction in arterial carbon dioxide tension would attenuate cerebral perfusion and improve dynamic cerebral autoregulation in healthy subjec...

journal_title：Critical care medicine

authors： Brassard P,Kim YS,van Lieshout J,Secher NH,Rosenmeier JB

更新日期：2012-06-01 00:00:00

abstract：:In a series of 56 patients (24 uncomplicated postoperative and 32 septic patients), neopterin and elastase alpha 1 protease inhibitor complex (E-alpha 1 PI) plasma levels were measured daily. The clinical course of each patient was evaluated with the Multiple Organ Failure (MOF) score according to Goris. Neopterin cou...

journal_title：Critical care medicine

authors： Pacher R,Redl H,Frass M,Petzl DH,Schuster E,Woloszczuk W

更新日期：1989-03-01 00:00:00

abstract：:A commercially available gas-chromatograph (Sentorr Gas Analyzer, Ohio Medical Products, Madison, WI) was tested, featuring continuous measurement of in vivo PaO2 and PaCO2 by means of a thin, heparin-coated catheter, inserted through an indwelling arterial line. Gas tensions are displayed every 4 min. The probes had ...

journal_title：Critical care medicine

authors： Carlon GC,Kahn RC,Ray C Jr,Howland WS

更新日期：1980-07-01 00:00:00

abstract：OBJECTIVE:Clinical predictors for acute respiratory distress syndrome (ARDS) have been studied in few prospective studies. Although transfusions are common in the intensive care unit, the role of submassive transfusion in non-trauma-related ARDS has not been studied. We describe here the clinical predictors of ARDS ris...

journal_title：Critical care medicine

authors： Gong MN,Thompson BT,Williams P,Pothier L,Boyce PD,Christiani DC

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Acute respiratory distress syndrome is occasionally seen in newborn infants due to a severe inflammatory process in the lungs that affects capillary-alveolar permeability, epithelial integrity, and type I and II pneumocyte function. The aim of this study was to investigate the effect of a topically applied nu...

journal_title：Critical care medicine

authors： Ankermann T,Reisner A,Wiemann T,Krams M,Köhler H,Krause MF

更新日期：2005-06-01 00:00:00

abstract：:Intralipid elimination patterns were compared in 25 healthy controls, 12 patients recovering from uncomplicated cholecystectomy, and 25 critically ill patients. The intravenous fat tolerance test revealed a similar fractional removal rate (k2) in healthy controls and critically ill patients, but k2 was increased in ch...

journal_title：Critical care medicine

authors： Lindh A,Lindholm M,Rössner S

更新日期：1986-05-01 00:00:00

abstract：OBJECTIVES:To describe the impact of choice of therapy on renal recovery. DESIGN:Literature review. MAIN RESULTS:Randomized controlled trials conducted have not shown a benefit of continuous renal replacement therapy in mortality over intermittent renal replacement therapy. However, renal recovery is another importan...

journal_title：Critical care medicine

authors： Uchino S

更新日期：2008-04-01 00:00:00

abstract：:During the control period in this study, small premature infants, 1500 g in birth weight, had insensible water loss (IWL) of 2.28 g/kg/hr (equivlaent to 54 ml/kg/day), which is considerably higher than in full term infants. Under phototherapy, there was a significant increase in IWL (3.14 g/kg/hr) associated with incr...

journal_title：Critical care medicine

authors： Yeh TF,Vidyasagar D,Pildes RS

更新日期：1975-11-01 00:00:00

abstract：:Newer pulmonary function instruments make measurement of small airway function possible as a routine, inexpensive part of preoperative preparation of patients with obstructive lung disease. Patients with early stages of chronic obstructive lung disease have maldistribution of ventilation and perfusion producing an inc...

journal_title：Critical care medicine

authors： Chodoff P,Margand PM,Knowles CL

更新日期：1975-07-01 00:00:00

abstract：:It was found that, during 1974, it cost an average of $8842 ($12,909 in 1979) to care for a survivor of severe respiratory distress syndrome (RDS) who required mechanical ventilation in this ICU compared to $2448 ($3574 in 1979) for nonsurvivors. Death in 15 out of the 16 nonsurvivors was accompanied by grade III-IV i...

journal_title：Critical care medicine

authors： Shannon DC,Crone RK,Todres ID,Krishnamoorthy KS

更新日期：1981-02-01 00:00:00

abstract：OBJECTIVE:To study the rate of elimination of ethanol after a major burn trauma. DESIGN:Prospective, controlled study. SETTING:National burns unit in a Swedish university hospital. PATIENTS AND SUBJECTS:Eight consecutive patients suffering from 18%-72% total burned surface area and nine healthy male control subjects...

journal_title：Critical care medicine

authors： Zdolsek HJ,Sjöberg F,Lisander B,Jones AW

更新日期：1999-12-01 00:00:00

abstract：:We found that altering aspirating flow rate (ASR) and sample tubing length (STL) affected the response time and capnogram of 2 different side-stream capnometers. Increased flow rate shortened rise time, transit time, and total delay time (TDT), whereas increased STL increased transit and TDTs but not rise time. Increa...

journal_title：Critical care medicine

authors： Schena J,Thompson J,Crone RK

更新日期：1984-08-01 00:00:00

abstract：OBJECTIVES:Cognitive deficits after traumatic brain injury are a leading cause of disability worldwide, yet no effective pharmacologic treatments exist to improve cognition. Traumatic brain injury increases proinflammatory cytokines, which trigger excess function of α5 subunit-containing γ-aminobutyric acid type A rece...

journal_title：Critical care medicine

authors： Khodaei S,Avramescu S,Wang DS,Sheng H,Chan NK,Lecker I,Fernandez-Escobar A,Lei G,Dewar MB,Whissell PD,Baker AJ,Orser BA

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:To investigate family perceptions of having a nurse participating in family conferences and to assess the psychologic well being of the same families after ICU discharge. DESIGN:Mixed-method design with a qualitative study embedded in a single-center randomized study. SETTING:Twelve-bed medical-surgical IC...

journal_title：Critical care medicine

authors： Garrouste-Orgeas M,Max A,Lerin T,Grégoire C,Ruckly S,Kloeckner M,Brochon S,Pichot E,Simons C,El-Mhadri M,Bruel C,Philippart F,Fournier J,Tiercelet K,Timsit JF,Misset B

更新日期：2016-06-01 00:00:00