Comparison of two simplified severity scores (SAPS and APACHE II) for patients with acute myocardial infarction.

abstract：OBJECTIVE:Currently 162-325 mg aspirin is recommended for the treatment of acute coronary syndrome. We tested the effect of an additional loading dose of 250 mg aspirin at the onset of acute coronary syndrome in patients who were already on chronic therapy with 100 mg aspirin. DESIGN:This was a prospective trial in pa...

journal_title：Critical care medicine

authors： Fuchs I,Spiel AO,Frossard M,Derhaschnig U,Riedmüller E,Jilma B

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Spread of multidrug-resistant organisms within the intensive care unit (ICU) results in substantial morbidity and mortality. Novel strategies are needed to reduce transmission. This study sought to determine if the use of daily chlorhexidine bathing would decrease the incidence of colonization and bloodstream...

journal_title：Critical care medicine

authors： Climo MW,Sepkowitz KA,Zuccotti G,Fraser VJ,Warren DK,Perl TM,Speck K,Jernigan JA,Robles JR,Wong ES

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To determine the role of serum albumin concentration as a predictor of mechanical ventilation dependency. DESIGN:Prospective, observation trial. SETTING:Multidisciplinary intensive care unit (ICU) in a university hospital. PATIENTS:One hundred forty-five consecutive patients who required mechanical ventila...

journal_title：Critical care medicine

authors： Sapijaszko MJ,Brant R,Sandham D,Berthiaume Y

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:To determine whether mechanical ventilation using high tidal volume is associated with nonpulmonary organ dysfunction that can be attenuated by dexamethasone. DESIGN:Prospective randomized animal intervention study. SETTING:Animal care facility in a university hospital. SUBJECTS:Sedated and tracheostomized...

journal_title：Critical care medicine

authors： Nin N,Peñuelas O,de Paula M,Lorente JA,Fernández-Segoviano P,Esteban A

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To present electron micrographs of lung tissue obtained from a patient exposed to high ventilatory pressures in the context of pulmonary dysfunction and pulmonary hypertension. DESIGN:Case report. SETTING:Adult intensive care unit of a university-affiliated teaching hospital. PATIENTS:A patient exposed to ...

journal_title：Critical care medicine

authors： Hotchkiss JR,Simonson DA,Marek DJ,Marini JJ,Dries DJ

更新日期：2002-10-01 00:00:00

abstract：:Recent strides in computational biology and high-throughput technologies have generated considerable interest in understanding complex biological systems. The application of these technologies to critical illness and injury offers the potential to define adaptive and maladaptive programs of gene expression induced by ...

journal_title：Critical care medicine

authors： Cobb JP,Suffredini AF,Danner RL

更新日期：2008-10-01 00:00:00

abstract：:Twenty-one patients who underwent cardiopulmonary bypass for myocardial revascularization received postoperatively controlled mechanical ventilation (CMV) or intermittent mandatory ventilation (IMV), with or without positive end-expiratory pressure (PEEP). Functional residual capacity (FRC), right-to-left intrapulmona...

journal_title：Critical care medicine

authors： Downs JB,Mitchell LA

更新日期：1976-11-01 00:00:00

abstract：OBJECTIVE:High-frequency oscillation has been proposed for use in adult acute respiratory distress syndrome. However, limited data are available on the effect of pressure amplitude and rate (Hz) on tidal volumes delivered during high-frequency oscillation in adults. DESIGN:Prospective, animal model, lung injury study....

journal_title：Critical care medicine

authors： Sedeek KA,Takeuchi M,Suchodolski K,Kacmarek RM

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Vascular dysfunction plays a central role in sepsis, and it is characterized by hypotension and hyporesponsiveness to vasoconstrictors. Nitric oxide is regarded as a central element of sepsis vascular dysfunction. The high amounts of nitric oxide produced during sepsis are mainly derived from the inducible is...

journal_title：Critical care medicine

authors： Nardi GM,Scheschowitsch K,Ammar D,de Oliveira SK,Arruda TB,Assreuy J

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:The high incidence of lower lobe collapse in adult intensive care patients is well described. We aimed to document the incidence and distribution of acute lobar collapse in the pediatric intensive care setting. The influence of anatomical and pathophysiological differences between the adult and pediatric resp...

journal_title：Critical care medicine

authors： Thomas K,Habibi P,Britto J,Owens CM

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVES:High physical activity levels are associated with wide-ranging health benefits, disease prevention, and longevity. In the present study, we examined the impact of regular physical exercise on the severity of organ injury and survival probability, as well as characteristics of the systemic immune and metaboli...

journal_title：Critical care medicine

authors： Sossdorf M,Fischer J,Meyer S,Dahlke K,Wissuwa B,Seidel C,Schrepper A,Bockmeyer CL,Lupp A,Neugebauer S,Schmerler D,Rödel J,Claus RA,Otto GP

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Preoperative intra-aortic balloon pumping (IABP) improves the results of complex coronary surgery. However, its insertion may be harmful or contraindicated in cases of severe and diffuse atherosclerosis of the descending aorta and peripheral arteries. We sought to evaluate the efficacy and safety of transbrac...

journal_title：Critical care medicine

authors： Onorati F,Bilotta M,Pezzo F,Impiombato B,Caroleo S,Santangelo E,Renzulli A

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:Trauma induces a complex immune response that requires a systems biology research approach. Here, we used a novel technology, mass cytometry by time-of-flight, to comprehensively characterize the multicellular response to trauma. DESIGN:Peripheral blood mononuclear cells samples were stained with a 38-marker...

journal_title：Critical care medicine

authors： Seshadri A,Brat GA,Yorkgitis BK,Keegan J,Dolan J,Salim A,Askari R,Lederer JA

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:To determine whether mean arterial blood pressure excursions below the lower limit of cerebral blood flow autoregulation during cardiopulmonary bypass are associated with acute kidney injury after surgery. SETTING:Tertiary care medical center. PATIENTS:Four hundred ten patients undergoing cardiac surgery w...

journal_title：Critical care medicine

authors： Ono M,Arnaoutakis GJ,Fine DM,Brady K,Easley RB,Zheng Y,Brown C,Katz NM,Grams ME,Hogue CW

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:Ethicists advise that life-sustaining treatment decisions should be made in keeping with patient preferences. Until recently, there has been little systematic study of the impact of patient preferences on the use of various life-sustaining treatments or the consequent cost of hospital care. This prospective ...

journal_title：Critical care medicine

authors： Danis M,Mutran E,Garrett JM,Stearns SC,Slifkin RT,Hanson L,Williams JF,Churchill LR

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of increasing the preoxygenation period with 100% oxygen in the critically ill patient from 4 to 8 mins in preparation for emergency tracheal intubation. DESIGN:Nonrandomized, controlled trial. SETTING:Large, level one trauma center, tertiary care intensive care unit. PATIENT...

journal_title：Critical care medicine

authors： Mort TC,Waberski BH,Clive J

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Hyperammonemia is a key contributing factor for cerebral edema in acute liver failure. Continuous renal replacement therapy may help reduce ammonia levels. However, the optimal timing, mode, intensity, and duration of continuous renal replacement therapy in this setting are unknown. We aimed to study continu...

journal_title：Critical care medicine

authors： Warrillow S,Fisher C,Bellomo R

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:To evaluate if the up-regulation of vascular endothelial growth factor strengthens the protective effect of amniotic fluid stem cells in a renal ischemia-reperfusion injury model. DESIGN:Randomized animal study. SETTINGS:University research laboratory. SUBJECTS:A total of 40 males 12-week-old Wistar rats w...

journal_title：Critical care medicine

authors： Mori da Cunha MG,Zia S,Beckmann DV,Carlon MS,Arcolino FO,Albersen M,Pippi NL,Graça DL,Gysemans C,Carmeliet P,Levtchenko E,Deprest J,Toelen J

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:To assess whether, in patients under mechanical ventilation, fluid responsiveness is predicted by the effects of short respiratory holds on cardiac index estimated by esophageal Doppler. DESIGN:Prospective, monocentric study. SETTING:Medical ICU. PATIENTS:Twenty-eight adult patients with acute circulatory...

journal_title：Critical care medicine

authors： Dépret F,Jozwiak M,Teboul JL,Alphonsine JE,Richard C,Monnet X

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To compare the outcomes and the short- and long-term complications of percutaneous translaryngeal tracheostomy (TLT) and surgical tracheostomy (ST). DESIGN:Prospective, randomized clinical trial with 1-yr double-blind follow-up. SETTING:A general intensive care unit of a university hospital. PATIENTS:A tot...

journal_title：Critical care medicine

authors： Antonelli M,Michetti V,Di Palma A,Conti G,Pennisi MA,Arcangeli A,Montini L,Bocci MG,Bello G,Almadori G,Paludetti G,Proietti R

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To document the effects of propofol on the hemodynamic and inflammatory responses to endotoxemia in an animal model. DESIGN:Randomized, prospective laboratory study. SETTING:University experimental laboratory. SUBJECTS:Thirty-two male rats. INTERVENTIONS:The animals were randomly assigned to one of four g...

journal_title：Critical care medicine

authors： Taniguchi T,Yamamoto K,Ohmoto N,Ohta K,Kobayashi T

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the pathophysiology involved in hypocalcemia in septic shock and to investigate the value of calcium administration. DESIGN:Prospective, randomized placebo-controlled trial with parallel groups. SETTING:Animal research laboratory at the University Hospital of Uppsala. SUBJECTS:Twenty-four pigs ...

journal_title：Critical care medicine

authors： Carlstedt F,Eriksson M,Kiiski R,Larsson A,Lind L

更新日期：2000-08-01 00:00:00

abstract：:There is an increasing evidence that survivors of critical illness suffer from impaired health-related quality of life. There are relatively few studies that have evaluated the effect of interventions in clinical trials to improve these long-term outcomes. Studies to improve long-term outcomes after critical illness f...

journal_title：Critical care medicine

authors： Rubenfeld GD

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:Most studies have assessed conflict between clinicians and surrogate decision makers in ICUs from only clinicians' perspectives. It is unknown if surrogates' perceptions differ from clinicians'. We sought to determine the degree of agreement between physicians and surrogates about conflict and to identify pre...

journal_title：Critical care medicine

authors： Schuster RA,Hong SY,Arnold RM,White DB

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:To evaluate knowledge translation after publication of the target temperature management 33°C versus 36°C after out-of-hospital cardiac arrest trial and associated patient outcomes. Our primary hypothesis was that target temperature management at 36°C was rapidly adopted in Australian and New Zealand ICUs. S...

journal_title：Critical care medicine

authors： Salter R,Bailey M,Bellomo R,Eastwood G,Goodwin A,Nielsen N,Pilcher D,Nichol A,Saxena M,Shehabi Y,Young P,Australian and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation (ANZICS-CORE).

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:Secretoneurin is associated with cardiomyocyte Ca handling and improves risk prediction in patients with acute myocardial dysfunction. Whether secretoneurin improves risk assessment on top of established cardiac biomarkers and European System for Cardiac Operative Risk Evaluation II in patients undergoing ca...

journal_title：Critical care medicine

authors： Brynildsen J,Petäjä L,Myhre PL,Lyngbakken MN,Nygård S,Stridsberg M,Christensen G,Ottesen AH,Pettilä V,Omland T,Røsjø H

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To assess clinician perceptions of a machine learning-based early warning system to predict severe sepsis and septic shock (Early Warning System 2.0). DESIGN:Prospective observational study. SETTING:Tertiary teaching hospital in Philadelphia, PA. PATIENTS:Non-ICU admissions November-December 2016. INTERVE...

journal_title：Critical care medicine

authors： Ginestra JC,Giannini HM,Schweickert WD,Meadows L,Lynch MJ,Pavan K,Chivers CJ,Draugelis M,Donnelly PJ,Fuchs BD,Umscheid CA

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:To establish Department of Veterans Affairs' intensive care unit (ICU) costs from a database and to use this information to validate the Russell equation, the most commonly used method of calculating ICU costs. To compare and trend Department of Veterans Affairs' and nationwide (USA) ICU and healthcare costs...

journal_title：Critical care medicine

authors： Halpern NA,Bettes L,Greenstein R

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:Anemia increases risk of bleeding complications in the critically ill. In primary intracerebral hemorrhage (ICH), the most fatal type of stroke, outcome is largely dependent on the volume of hemorrhage into the brain. We investigated the relationship between anemia and clinical course of acute ICH. METHODS:S...

journal_title：Critical care medicine

authors： Kumar MA,Rost NS,Snider RW,Chanderraj R,Greenberg SM,Smith EE,Rosand J

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:This study aims to explore the relationship between team-leadership skills and quality of cardiopulmonary resuscitation in an adult cardiac-arrest simulation. Factors affecting team-leadership skills were also assessed. DESIGN:Forty advanced life-support providers leading a cardiac arrest team in a standardi...

journal_title：Critical care medicine

authors： Yeung JH,Ong GJ,Davies RP,Gao F,Perkins GD

更新日期：2012-09-01 00:00:00